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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Ketograce DS Tablet is used to treat chronic kidney disease. It contains Alpha Ketoanalogue, which works by lowering urea levels in the blood and improving kidney function. In some cases, this medicine may cause side effects such as increased calcium levels, nausea, vomiting, diarrhoea, and abdominal pain. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Composition :

ALPHA KETOANALOGUE

Manufacturer/Marketer :

Biokindle Lifesciences Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Ketograce DS Tablet

Ketograce DS Tablet is widely used in the treatment of chronic kidney disease. Chronic kidney disease (CKD) is a long-term condition where the kidneys don't work as they should.

Ketograce DS Tablet contains Alpha Ketoanalogue, which prevents the unnecessary increase in urea levels in the blood due to the intake of non-essential amino acids in patients with kidney failure. Thereby improving renal function.

Not everyone who takes Ketograce DS Tablet will experience these side effects. Common side effects of Ketograce DS Tablet include increased calcium levels, nausea, vomiting, diarrhoea, and abdominal pain. Most of these side effects do not require medical attention and will resolve gradually over time.

Take Ketograce DS Tablet with food orally (by mouth). Depending on your medical condition, your doctor will decide the dose and duration of the medicine. However, it is advised not to take more than the prescribed dose of Ketograce DS Tablet .

Do not take Ketograce DS Tablet if you are allergic to any components present in Ketograce DS Tablet . Inform your physician if you are pregnant or a breastfeeding mother before using Ketograce DS Tablet . Please do not stop taking Ketograce DS Tablet without consulting your doctor. Avoid consuming alcohol during the treatment to avoid unpleasant side effects.

Uses of Ketograce DS Tablet

Ketograce DS Tablet used in the treatment of chronic kidney disease (CKD). The detailed uses of Ketograce DS Tablet are as follows:

  • Chronic Kidney Disease (CKD): Ketograce DS Tablet helps to manage CKD by reducing the accumulation of nitrogen waste products in the blood, slowing disease progression, and delaying the need for dialysis.
  • Kidney Function Support: Ketograce DS Tablet supports kidney function by reducing uremia and waste accumulation, providing essential amino acids, and reducing the strain on the kidneys.
  • Enhances Nutritional Status: Ketograce DS Tablet improves nutritional status with essential ketoacids, promoting protein synthesis, reducing muscle wasting, and enhancing overall health.

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Directions for Use

  • Ketograce DS Tablet can be taken with meals to increase absorption and effectively support the body's amino acid levels.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Dissolve the contents in a full glass of water or, as suggested by your doctor, stir well and drink it right away.
  • Do not store the dissolved mixture for later use.

Medicinal Benefits

  • Ketograce DS Tablet is used in the treatment of chronic kidney disease.
  • Ketograce DS Tablet is best if taken along with a low-protein diet, as it helps delay the progression of kidney diseases.
  • Make healthy lifestyle changes and ensure that your underlying conditions are well-managed.

How Ketograce DS Tablet Works

Ketograce DS Tablet contains 'Alpha Ketoanalogue', which prevents the unnecessary increase in urea levels in the blood due to the intake of non-essential amino acids in patients with kidney failure. Thereby improving renal function.

Storage

• Store in a cool and dry place away from sunlight.• Keep Ketograce DS Tablet out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Ketograce DS Tablet
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.

What if I have taken an overdose of Ketograce DS Tablet

Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include hypotension (low blood pressure), fever, rapid pulse, and general symptoms of shock. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

  • Do not take Ketograce DS Tablet if you are allergic to any components present in it.
  • It is advised not to stop taking Ketograce DS Tablet without consulting your doctor.
  • Ketograce DS Tablet should be used in pregnant and breastfeeding women only if clinically needed and the benefits outweigh the risks.
  • Avoid consuming alcohol along with Ketograce DS Tablet  as it may lead to unpleasant side effects.
  • People with chronic kidney disease (CKD) may need to closely monitor sodium and phosphorus in foods, especially if their kidney disease is advanced.
  • Ketograce DS Tablet is not recommended for use in children below 18 years of age as the safety has not been established.
  • It is always important to check the expiry of the medicine. Discard the medicine if it reaches the expiry date.
     

Drug-Drug Interactions

verifiedApollotooltip
TryptophanSafinamide
Critical
TryptophanTranylcypromine
Critical

Drug-Drug Interactions

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TryptophanSafinamide
Critical
How does the drug interact with Ketograce DS Tablet:
Taking Safinamide with Ketograce DS Tablet can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Safinamide with Ketograce DS Tablet is not recommended as it can possibly result in an interaction, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and loose stools. Do not discontinue any medications without consulting your doctor.
TryptophanTranylcypromine
Critical
How does the drug interact with Ketograce DS Tablet:
Taking tranylcypromine with Ketograce DS Tablet can increase the risk of serotonin syndrome ( high levels of serotonin in body which result in shivering, high fever, diarrhea & muscle stiffness) .

How to manage the interaction:
Taking Tranylcypromine with Ketograce DS Tablet is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
TryptophanParoxetine
Severe
How does the drug interact with Ketograce DS Tablet:
Coadministration of Paroxetine with Ketograce DS Tablet can increase the side effects of paroxetine.

How to manage the interaction:
Although there is a possible interaction between Paroxetine and Ketograce DS Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
TryptophanCyclobenzaprine
Severe
How does the drug interact with Ketograce DS Tablet:
Taking Cyclobenzaprine with Ketograce DS Tablet might raise serotonin hormone levels which can increase the risk of developing side effects.

How to manage the interaction:
Taking Cyclobenzaprine with Ketograce DS Tablet can possibly lead to an interaction. It can be taken if prescribed by doctor. However, if you experience fever, palpitations, excessive sweating, muscle spasm, or diarrhea, contact a doctor immediately. Do not discontinue the medications without consulting a doctor.
TryptophanVenlafaxine
Severe
How does the drug interact with Ketograce DS Tablet:
When venlafaxine is taken with Ketograce DS Tablet, the risk of serotonin syndrome increases (a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
There may be a possibility of interaction between Venlafaxine and Ketograce DS Tablet, but it can be taken if prescribed by a doctor. However, if you experience any of the following symptoms: confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea, seek immediate medical attention. Do not discontinue any medications without consulting a doctor.
TryptophanAmitriptyline
Severe
How does the drug interact with Ketograce DS Tablet:
Combining Ketograce DS Tablet with Amitriptyline can increase the risk of serotonin syndrome.(A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Although using Ketograce DS Tablet and Amitriptyline together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have symptoms such as confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Inform a doctor if you have recently taken amitriptyline. Do not discontinue any medications without consulting a doctor.
TryptophanClomipramine
Severe
How does the drug interact with Ketograce DS Tablet:
The combined use of Ketograce DS Tablet with clomipramine can cause serotonin syndrome. Serotonin syndrome is a condition in which a chemical called serotonin builds up in your body, causing signs and symptoms ranging from mild (shivering and diarrhea) to severe (muscle rigidity, fever, and seizures).

How to manage the interaction:
Although taking clomipramine and Ketograce DS Tablet together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience symptoms such as confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, incoordination, stomach pain, nausea, vomiting, and diarrhoea, consult the doctor. Do not discontinue any medications without consulting a doctor.
TryptophanPentazocine
Severe
How does the drug interact with Ketograce DS Tablet:
Coadministration of Pentazocine with Ketograce DS Tablet may increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Although there is a interaction between Pentazocine and Ketograce DS Tablet, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
TryptophanSelegiline
Severe
How does the drug interact with Ketograce DS Tablet:
When Ketograce DS Tablet is taken with Selegiline, may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
There may be a possibility of interaction between Ketograce DS Tablet and Selegiline, but it can be taken if prescribed by a doctor. If you notice any of these signs - like confusion, hallucination, fits, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea-call a doctor. Do not stop using any medications without a doctor's advice.
TryptophanDesvenlafaxine
Severe
How does the drug interact with Ketograce DS Tablet:
Co-administration of Ketograce DS Tablet and Desvenlafaxine might raise serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to severe side effects.

How to manage the interaction:
Co-administration of Ketograce DS Tablet and Desvenlafaxine can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea, consult the doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • ​​It is best if taken along with a low-protein diet as it helps delay the progression of kidney diseases.
  • People with kidney problems are advised to limit sodium in their diet, including added salt.
  • Olive oil is a healthy source of fat- and phosphorus-free source, making it an excellent option for people with kidney disease.
  • Bulgur is a whole-grain wheat product that is a terrific, kidney-friendly alternative to other whole grains high in phosphorus and potassium.
  • Blueberries are packed with nutrients and are one of the best sources of antioxidants you can eat.

Habit Forming

No

Therapeutic Class

NUTRITIONAL SUPPLEMENT

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Alcohol

Unsafe

You are recommended not to consume alcohol along with Ketograce DS Tablet to avoid unpleasant side effects.

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Pregnancy

Consult your doctor

Ketograce DS Tablet should be used in pregnant women only if clinically needed, and the benefits outweigh the risks. Please consult the doctor; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Caution should be exercised, and it is advisable to consult a doctor before using it. The doctor will prescribe if the doctor thinks the benefits outweigh the risks.

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Driving

Caution

Drive only if you are physically stable and mentally focused. If you experience drowsiness after taking this medication, you should not drive or operate machinery or vehicles.

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Liver

Consult your doctor

Inform your doctor before receiving the Ketograce DS Tablet if you have a liver impairment. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Safe if prescribed

Ketograce DS Tablet can be taken safely when prescribed. Usually, it does not affect the kidney.

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Children

Unsafe

The safety and efficacy of Ketograce DS Tablet in children have not been established. Ketograce DS Tablet is not recommended in children.

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Heart

Safe if prescribed

Ketograce DS Tablet is generally considered safe for heart patients when used at prescribed doses. However, please consult your doctor if you have any concerns.

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Geriatrics

Consult your doctor

Limited information is available regarding the usage of Ketograce DS Tablet in elders, so please consult a doctor if you have any concerns.

FAQs

Ketograce DS Tablet is used in the treatment of chronic kidney disease.

To treat your condition effectually, continue taking Ketograce DS Tablet for as long as your doctor has prescribed. Please do not stop taking Ketograce DS Tablet without consulting your doctor.

CKD is usually caused by various conditions such as high blood pressure, diabetes, high cholesterol, kidney infections, kidney inflammation, kidney stones that keep coming back, an enlarged prostate, and long-term or regular use of certain medicines such as lithium and non-steroidal anti-inflammatory drugs (NSAIDs).

CKD can be diagnosed using blood and urine tests. These tests look for high levels of certain substances in the blood and urine that show your kidneys are malfunctioning. The results of these tests can be used to determine the stage of your kidney disease.

There are usually no symptoms of kidney disease in the early stages. At a more advanced stage, symptoms can include tiredness, swollen ankles, feet or hands, shortness of breath, feeling sick, and blood in your pee (urine). It may only be diagnosed if you have a blood or urine test for another reason, and the results show a possible problem with your kidneys.

Ketograce DS Tablet mimics the same catabolic pathways as amino acids and works by improving the body's metabolism, thereby improving renal function.

Country of origin

India

Manufacturer/Marketer address

A/412, Siddhi Vinayak Towers, Off S G Highway, Makarba, Ahmedabad - 380051 , Gujarat, INDIA
Other Info - KET0553

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