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  3. Ketoflam SR Tablet 10's

Ketoflam SR Tablet 10's, Pack of 10 TABLETS
Ketoflam SR Tablet 10's, Pack of 10 TABLETS
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Ketoflam SR Tablet contains flupirtine maleate which is an NSAID (Non-Steroidal Anti-Inflammatory Drugs) medicine. It is mainly used to relieve mild to moderate pain and swelling caused by osteoarthritis and rheumatoid arthritis, and also post-operative pain. This medicine inhibits cyclo-oxygenase (COX) enzymes and this helps reduce pain. You may experience certain common side effects such as dizziness, drowsiness, pruritus (itchy skin), dry mouth and gastric fullness, nausea and muscle tremor.
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Composition :

FLUPIRTINE MALEATE-400MG

Manufacturer/Marketer :

Lupin Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Ketoflam SR Tablet

Ketoflam SR Tablet belongs to a group of 'non-opioid analgesics' medicines used to relieve mild to moderate pain and inflammation associated with musculoskeletal pain. Pain is an unpleasant sensation and emotional experience associated with tissue damage. It allows the body to react and prevent further tissue damage. Pain can be short-term (acute) or long-term (chronic). Pain perception can differ from person to person, from tolerable to non-tolerable.

Ketoflam SR Tablet compromises of 'Flupirtine Maleate' that exerts dual effects by relaxing muscles and treating pain. It works by blocking the signals responsible for the sense of pain and inflammation produced at the sites of injury and damage.

Take Ketoflam SR Tablet as prescribed by your doctor. You are suggested to take Ketoflam SR Tablet as long as your doctor has prescribed it after checking your medical condition. Some persons may experience common side effects like dizziness, drowsiness, pruritus (itchy skin), dry mouth and gastric fullness, nausea and muscle tremor. Most of the side effects of Ketoflam SR Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Do not take Ketoflam SR Tablet if you are hypersensitive to any component present in Ketoflam SR Tablet . Pregnant and nursing mothers should not take Ketoflam SR Tablet unless prescribed by the doctor. Ketoflam SR Tablet may cause drowsiness and dizziness, so drive with caution. Ketoflam SR Tablet should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol while using Ketoflam SR Tablet as it could lead to increased drowsiness and dizziness; it might also increase stomach bleeding risk. Do not take other painkillers with Ketoflam SR Tablet unless prescribed by the doctor. Keep your doctor informed about your health condition and medicines to rule out any side effects. People with hepatic encephalopathy, myasthenia gravis, liver problems, or tinnitus should not take this medicine as it may lead to life-threatening conditions.

Uses of Ketoflam SR Tablet

Treatment of Pain

Directions for Use

• Take Ketoflam SR Tablet with food to prevent stomach upset or as advised by your doctor.• It is advised to take Ketoflam SR Tablet 3 times daily; however, follow your doctor's recommendation regarding the dosage and duration.• Swallow the tablet as a whole with a glass of water.• Do not crush, chew or break it.

Medicinal Benefits

Ketoflam SR Tablet is used to relieve mild to moderate pain and inflammation associated with muscle pain involving the musculoskeletal system, tension headaches, dental extraction, muscle spasm, tumour or cancer pain, and pain after trauma-related/orthopaedic surgery and injuries. Additionally, Ketoflam SR Tablet also relieves symptoms of abnormal menses cycle like menstrual period pain, premenstrual syndrome symptoms (PMS) and heavy menstrual period management in women. Ketoflam SR Tablet exerts dual effects by relaxing muscles and treating pain. It works by blocking the signals responsible for the sense of pain and inflammation produced at the sites of injury and damage. Ketoflam SR Tablet has better tolerability than other painkillers and has low gastric problems (like gastrointestinal bleeding, ulcer and blockage).

How Ketoflam SR Tablet Works

Ketoflam SR Tablet compromises of 'Flupirtine Maleate' that exerts dual effects by relaxing muscles and treating pain. It works by blocking the signals responsible for the sense of pain and inflammation produced at the sites of injury and damage.

Storage

• Store in a cool and dry place away from sunlight.
• Keep out of sight and reach of children.
• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Ketoflam SR Tablet
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Get enough sleep. Maintain a regular sleep cycle.
  • Eat a healthy diet and exercise regularly.
  • Manage stress with yoga or meditation.
  • Limit alcohol and caffeine.
  • Avoid driving or operating machinery unless you are alert.
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Notify your doctor immediately if you experience tremors or involuntary shaking after taking medication or adjusting your medication regimen.
  • Your doctor may adjust your medication regimen or recommend alternative techniques like relaxation, meditation, or journaling to alleviate tremor symptoms.
  • Your doctor may direct you to practice stress-reducing techniques, such as deep breathing exercises, yoga, or journaling.
  • Regular physical activity, such as walking or jogging, can help reduce anxiety and alleviate tremor symptoms.
  • Your doctor may recommend lifestyle changes, such as avoiding caffeine, getting enough sleep, and staying hydrated, to help manage tremors.
  • Maintain regular follow-up appointments with your doctor to monitor tremor symptoms and adjust treatment plans as needed.

What if I have taken an overdose of Ketoflam SR Tablet

Do not take more than the prescribed dose of Ketoflam SR Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

A person dealing with kidney problems, over 65 years of age or taking blood clotting (anticoagulants) medicines should only take Ketoflam SR Tablet after consulting with the doctor. Ketoflam SR Tablet is not recommended during pregnancy as the safety and efficacy are not established. However, your doctor may prescribe Ketoflam SR Tablet for you during pregnancy if the doctor feels the benefit to you outweighs the risk. While Ketoflam SR Tablet may pass in the lactating mother's breast milk, it is advisable to take it only if prescribed by your doctor. Ketoflam SR Tablet tends to cause stomach upset. Thus, consuming Ketoflam SR Tablet with meals is recommended to minimize gastric side effects. If you have a peptic ulcer diagnosis, Ketoflam SR Tablet is best avoided unless prescribed by your doctor. Ketoflam SR Tablet can cause liver injury when taken in large doses. Concomitant use of alcohol is best avoided as it aggravates liver toxicity. Although it is a safe medicine, it should be avoided in patients with kidney disease as the Ketoflam SR Tablet may hurt renal function. If you develop diarrhoea or vomiting when taking Ketoflam SR Tablet , consult your doctor about the continuation of Ketoflam SR Tablet as it can increase dehydration and lead to kidney damage. You should avoid consumption of alcohol during the treatment with Ketoflam SR Tablet as it may lead to an increased risk of liver damage. If you have a severe allergy to painkillers or have hepatic encephalopathy, myasthenia gravis any liver problems, then don't take the Ketoflam SR Tablet as it can cause serious side effects. 

Drug-Drug Interactions

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No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

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Drug-Food Interactions

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Diet & Lifestyle Advise

  • Rest well, and get plenty of sleep.
  • Massages can also be helpful.
  • Avoid freezing and hot temperatures.
  • Stay hydrated, and drink plenty of water.
  • Avoid wearing tight-fitting clothes; instead, wear loose garments.
  • Mild exercises such as jogging and walking are helpful for muscle stretching.
  • To avoid developing pressure sores, change your position every two hours.
  • Hot or cold therapy can help treat pain. Apply an ice pack or hot pack on the muscle for 15-20minutes.
  • Please do not go for heavy exercise as it may increase your joint pain in arthritis. Instead, you can do stretching and low-impact aerobic exercises like walking on a treadmill, bike riding, and swimming. You can also strengthen your muscle strength by lifting light weights.
  • Include more glucosamine, chondroitin sulfate, vitamin D, and calcium-enriched supplements. Besides this, turmeric and fish oils can help reduce inflammation in the tissue.

Habit Forming

No

Therapeutic Class

ANALGESICS
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Alcohol

Caution

Avoid consuming alcohol along with Ketoflam SR Tablet as it may lead to serious side effects.

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Pregnancy

Caution

There are no adequate and well-controlled studies on pregnant women. If you are pregnant, inform your doctor before taking Ketoflam SR Tablet . Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

If you are breastfeeding, inform your doctor before taking Ketoflam SR Tablet . Your doctor will prescribe only if the benefits outweigh the risks.

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Driving

Caution

Ketoflam SR Tablet causes drowsiness and dizziness, so drive only if you are alert.

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Liver

Caution

Take Ketoflam SR Tablet with caution if you have liver problems. Your doctor may suggest a liver function test based on your condition while taking this medicine.

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Kidney

Caution

Take Ketoflam SR Tablet with caution if you have kidney problems. Your doctor may suggest kidney function tests based on your condition while taking this medicine.

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Children

Caution

Ketoflam SR Tablet is not recommended for children under 12 years of age.

Have a query?

FAQs

Ketoflam SR Tablet belongs to a group of non-opioid analgesics medicines used to relieve mild to moderate pain and inflammation associated with musculoskeletal pain.

Ketoflam SR Tablet compromises of "Flupirtine Maleate" that exerts dual effects by relaxing muscles and treating pain. It works by blocking the signals responsible for the sense of pain and inflammation produced at the sites of injury and damage.

You can stop Ketoflam SR Tablet if it is only advised for short-term pain relief. In the case of long-term usage, it is advised to continue as advised by your doctor.

Ketoflam SR Tablet is used to relieve menstrual (period) pain, premenstrual syndrome (PMS) symptoms and management of excessively heavy periods. Take it as prescribed by the doctor.

For maximum benefits, take Ketoflam SR Tablet for the duration prescribed by your doctor.

A person dealing with kidney problems, over 65 years of age or taking blood clotting (anticoagulants) medicines should only take Ketoflam SR Tablet after consulting with the doctor. A person with liver problems (like hepatic encephalopathy), gall bladder problems (like cholestasis), muscle problems (like myasthenia gravis), chronic alcoholism, and biliary cirrhosis should avoid the use of Ketoflam SR Tablet unless prescribed by a doctor.

Persons taking Ketoflam SR Tablet may have false-positive results for urobilinogen, bilirubin and urine protein on urine test strips. So tell your lab assistant or doctor that you are taking Ketoflam SR Tablet before undergoing these diagnostics tests.

It is advised to avoid taking Ketoflam SR Tablet with medications containing paracetamol or carbamazepine as it can increase the sedative or muscle-relaxant properties of the medication.

Ketoflam SR Tablet should be taken orally. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

No, Ketoflam SR Tablet is not an antibiotic. It belongs to a group of medications called non-opioid analgesics, used to provide relief from mild to moderate pain and inflammation.

Although some clinical studies indicate that flupirtine maleate may be effective in treating fibromyalgia, it has not received official regulatory approval for this condition. Consult the doctor if you have fibromyalgia.

Ketoflam SR Tablet is often combined with paracetamol for enhanced pain relief. Flupirtine provides central analgesic and muscle relaxant effects, while paracetamol acts as a pain reliever. Together, they can offer more effective management of moderate to severe pain. However, Ketoflam SR Tablet should be taken with paracetamol only if advised by the doctor.

Yes, Ketoflam SR Tablet may cause liver toxicity when taken in larger doses. Therefore, avoid exceeding the recommended dose. Consult the doctor before taking Ketoflam SR Tablet if you have liver problems.

Yes, Ketoflam SR Tablet can be used to relieve pain associated with osteoarthritis and post-orthopaedic surgery. This is particularly beneficial for patients who cannot take NSAIDs due to the risk of NSAID-induced gastritis.

Case reports have noted that Ketoflam SR Tablet may cause green discolouration of urine, although this is uncommon. Consult the doctor if you notice this symptom.

Flupirtine maleate is not approved for the treatment of epilepsy. However, some animal studies have shown a beneficial effect of flupirtine for treating epilepsy and this effect is still being investigated.

Yes, you may experience withdrawal symptoms such as sweating, tremors and mood swings with long-term use of Ketoflam SR Tablet . Therefore, consult the doctor before stopping Ketoflam SR Tablet to prevent withdrawal symptoms.

The side effects of Ketoflam SR Tablet include nausea, drowsiness, dizziness, pruritus (itchy skin), dry mouth and gastric fullness, and muscle tremors. Consult the doctor if any of these symptoms persist or worsen.

Country of origin

India

Manufacturer/Marketer address

Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India Country of Origin: India
Other Info - KET0205

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Santoshini Reddy GDoctor badge

Reviewed By

Santoshini Reddy G

M Pharmacy

Last Updated

Jul 18, 2025 | 9:24 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://cdscoonline.gov.in/CDSCO/Drugs
  2. https://www.ema.europa.eu/en/news/restrictions-use-flupirtine-containing-medicines-cmdh-endorses-prac-recommendation#:~:text=Flupirtine%20is%20a%20non%2Dopioid,following%20orthopaedic%20surgery%20or%20injuries.
  3. https://www.mims.com/india/drug/info/viotensehttp://mri.cts-mrp.eu/download/DE_H_3519_001_FinalPL.pdf
  4. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3339720/

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