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  3. Kefzone 1 gm Injection 1's

Kefzone 1 gm Injection 1's, Pack of 1
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Written By ,
Reviewed By Praneetha Akunuri , M.Pharmacy

Kefzone 1 gm Injection 1's is used to treat various bacterial infections such as respiratory tract (lungs) infection, urine infection, blood infection, meningitis (inflammation of the brain and spinal cord), gonorrhoea (sexually transmitted disease), skin, abdominal, bone, and joint infections. It contains Cefoperazone, which works by preventing the formation of bacterial cell covering necessary for their survival by binding to the penicillin-binding proteins (PBPs), thus preventing cross-linking of nascent peptidoglycan and killing the bacteria. It may cause diarrhoea, allergic reactions, abnormal liver function tests, and anaemia (low number of red blood cells). Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

CEFOPERAZONE-1000MG

Manufacturer/Marketer :

Ang Healthcare India Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Kefzone 1 gm Injection 1's

Kefzone 1 gm Injection 1's belongs to the group of medicines called antibiotics used to treat various bacterial infections such as respiratory tract (lungs) infection, urine infection, blood infection, meningitis (inflammation of the brain and spinal cord), gonorrhoea (sexually transmitted disease), skin, abdominal, bone, and joint infections. Bacterial infections are caused due to the multiplication of harmful bacteria inside or on the body. Infectious or harmful bacteria can make you sick and reproduce quickly in your body. These harmful bacteria produce chemicals known as toxins, which can damage tissue and make you ill. Kefzone 1 gm Injection 1's does not work against infections caused by the virus, including cold and flu.

Kefzone 1 gm Injection 1's is an antibiotic that contains Cefoperazone (cephalosporin antibiotic). Kefzone 1 gm Injection 1's works by preventing the formation of bacterial cell covering, which is necessary for their survival by binding to the penicillin-binding proteins (PBPs), thus preventing cross-linking of nascent peptidoglycan and killing the bacteria. Thereby, Kefzone 1 gm Injection 1's helps to treat bacterial infections.

You may experience diarrhoea, allergic reactions, abnormal liver function tests, and anaemia (a low number of red blood cells). Most of these side effects of Kefzone 1 gm Injection 1's do not require medical attention and gradually resolve over time. However, if they persist, consult your doctor.

Before starting Kefzone 1 gm Injection 1's, please inform your doctor if you have any allergy (against any antibiotic), kidney or liver problems. Do not take Kefzone 1 gm Injection 1's on your own as self-medication may lead to antibiotic-resistance in which antibiotics fail to act against specific bacterial infections. Inform your doctor before taking Kefzone 1 gm Injection 1's if you are pregnant or planning for pregnancy. Avoid taking Kefzone 1 gm Injection 1's if you are breastfeeding as Kefzone 1 gm Injection 1's may pass into breast milk. Avoid alcohol consumption while taking Kefzone 1 gm Injection 1's to prevent unpleasant side effects.

Uses of Kefzone 1 gm Injection 1's

Kefzone 1 gm Injection 1's is used to treat bacterial infections in various parts of the body. The detailed uses of Kefzone 1 gm Injection 1's are as follows: <br/>• Respiratory Infections: Kefzone 1 gm Injection 1's treats upper and lower respiratory tract infections, including pneumonia, by inhibiting bacterial growth.<br/>• Urinary Tract Infections (UTIs): Kefzone 1 gm Injection 1's treats UTIs by eliminating bacteria that cause infections in the urinary system.<br/>• Skin & Soft Tissue Infections: Kefzone 1 gm Injection 1's treats infected wounds, cellulitis, and abscesses by targeting and killing bacteria that cause these infections.<br/>• Bone & Joint Infections: Kefzone 1 gm Injection 1's treats bone and joint infections by managing bacterial growth and reducing inflammation.<br/>• Septicemia: Kefzone 1 gm Injection 1's treats bloodstream infections by killing bacteria that cause septicemia.<br/>• Meningitis: Kefzone 1 gm Injection 1's treats bacterial meningitis by targeting bacteria that cause inflammation in the brain and spinal cord.<br/>• Gonorrhea: Kefzone 1 gm Injection 1's treats gonorrhea by eliminating the bacteria that cause this infection.<br/>• Intra-abdominal Infections: Kefzone 1 gm Injection 1's treats intra-abdominal infections, including biliary and pelvic infections, by targeting bacteria that cause these infections.<br/>

Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication.• Kefzone 1 gm Injection 1's is administered by the doctor or nurse.• Do not self-administer.

Medicinal Benefits

Kefzone 1 gm Injection 1's belongs to the group of medicines called antibiotics used to treat various bacterial infections such as respiratory tract (lungs) infection, urine infection, blood infection, meningitis (inflammation of the brain and spinal cord), gonorrhoea (sexually transmitted disease), skin, abdominal, bone, and joint infections. Kefzone 1 gm Injection 1's contains Cefoperazone (cephalosporin antibiotic). It works by preventing the formation of bacterial cell covering, which is necessary for their survival by binding to the penicillin-binding proteins (PBPs), thus preventing cross-linking of nascent peptidoglycan and killing the bacteria. Thus, Kefzone 1 gm Injection 1's helps to treat bacterial infections.

How Kefzone 1 gm Injection 1's Works

Kefzone 1 gm Injection 1's is an antibiotic that contains Cefoperazone (cephalosporin antibiotic). Kefzone 1 gm Injection 1's works by preventing the formation of bacterial cell covering, which is necessary for their survival by binding to the penicillin-binding proteins (PBPs), thus preventing cross-linking of nascent peptidoglycan and kills the bacteria. Thereby, Kefzone 1 gm Injection 1's helps to treat bacterial infections.

Storage

• Store in a cool and dry place away from sunlight.• Keep Kefzone 1 gm Injection 1's out of the sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Kefzone 1 gm Injection
  • Drink plenty of water to stay hydrated.
  • Avoid foods that can cause black stools, such as liquorice, blueberries, and iron-rich foods.
  • Practice stress-reducing techniques like meditation, deep breathing, or yoga to help minimize stress-related digestive issues.
  • Avoid taking medications that can cause black stools, such as iron supplements or bismuth subsalicylate.
  • Monitor your stool colour, consistency, and frequency to identify any changes or patterns.
  • Seek medical attention if you experience persistent or severe black stools, abdominal pain, or other symptoms.
  • Get tested if your doctor suspects an underlying condition, such as gastrointestinal bleeding or ulcers.
  • Make lifestyle changes, such as getting regular exercise and quitting smoking, to help improve overall digestive health.
  • Chest pain may last for a while and needs immediate medical attention as it is a significant health issue to be attended to.
  • Take rest and refrain from doing physical activity for a while, and restart after a few days.
  • Try applying an ice pack to the strained area for at least 20 minutes thrice a day. Ice pack thus helps reduce inflammation.
  • Sit upright and maintain proper posture if there is persistent chest pain. • Use extra pillows to elevate your position and prop your chest up while sleeping.
Here are the steps to manage the medication-triggered Cough:
  • Tell your doctor about the cough symptoms you're experiencing, which may be triggered by your medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your cough symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids, such as water, tea, or soup, to help thin out mucus and soothe your throat.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your cough persists or worsens, consult your doctor for further guidance.
Here are the seven steps to manage medication-triggered Dyspnea (Difficulty Breathing or Shortness of Breath):
  • Tell your doctor immediately if you experience shortness of breath after taking medication.
  • Your doctor may adjust the medication regimen or dosage or give alternative medical procedures to minimize the symptoms of shortness of breath.
  • Monitor your oxygen levels and breathing rate regularly to track changes and potential side effects.
  • For controlling stress and anxiety, try relaxation techniques like deep breathing exercises, meditation, or yoga.
  • Make lifestyle changes, such as quitting smoking, exercising regularly, and maintaining a healthy weight.
  • Seek emergency medical attention if you experience severe shortness of breath, chest pain, or difficulty speaking.
  • Follow up regularly with your doctor to monitor progress, adjust treatment plans, and address any concerns or questions.
  • Drink warm fluids such as warm water with honey, broth, soup or herbal tea to soothe sore throat.
  • Gargle with warm salt water.
  • Suck on lozenges to increase the production of saliva and soothe your throat.
  • Use a humidifier to soothe sore throat as it adds moisture to the air and makes breathing easier.
  • Follow your doctor's advice to manage underlying conditions causing swollen glands.
  • Apply a warm compress to reduce swelling and ease discomfort.
  • Gargle with warm salt water to soothe swelling in your neck or throat.
  • Wash your hands frequently, especially after contact with sick individuals.
  • Exercise regularly, like walking or yoga, to boost your immune system.
  • Monitor symptoms and consult your doctor if swelling lasts, increases, or is accompanied by fever, weight loss, or night sweats.

What if I have taken an overdose of Kefzone 1 gm Injection 1's

Kefzone 1 gm Injection 1's is administered by a health care professional in a hospital setting. Hence, the chances of overdose are less. However, if you suspect any adverse reactions or unusual symptoms while on treatment with Kefzone 1 gm Injection 1's, please inform your doctor immediately.

Drug Warnings

After taking Kefzone 1 gm Injection 1's if you have allergy-like symptoms including rash, swelling of the face/lips/throat, difficulty in breathing, or tightness in the chest, immediately contact your doctor. Do not take Kefzone 1 gm Injection 1's if you have an allergy to Kefzone 1 gm Injection 1's, cephalosporins penicillin class of antibiotics as it may cause a skin rash, itching, and difficulty in breathing. People having liver disease or jaundice (yellowing of skin/eye) should not take Kefzone 1 gm Injection 1's, as it can damage your liver severely. You may have diarrhoea in some cases as a common side effect which can be managed by taking it with any probiotics and plenty of fluids. Do not take antacids along with Kefzone 1 gm Injection 1's; maintain a gap of 2-3 hours between both. Avoid alcohol consumption while taking Kefzone 1 gm Injection 1's to prevent unpleasant side-effects. Kefzone 1 gm Injection 1's may cause dizziness, so be cautious while driving. Inform your doctor about all the medicines you are taking and about your health condition to rule out any unpleasant side-effects.

Drug-Drug Interactions

verifiedApollotooltip
CeftriaxoneCalcium chloride
Critical
CeftriaxoneCalcium gluconate
Critical

Drug-Drug Interactions

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CeftriaxoneCalcium chloride
Critical
How does the drug interact with Kefzone 1 gm Injection:
Co-administration of Calcium chloride with Kefzone 1 gm Injection can increase the risk of side effects.

How to manage the interaction:
Taking Kefzone 1 gm Injection with Calcium chloride is not recommended, but can be taken together if prescribed by a doctor. However, consult your doctor if you experience any unusual symptoms contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
CeftriaxoneCalcium gluconate
Critical
How does the drug interact with Kefzone 1 gm Injection:
Co-administration of Calcium gluconate with Kefzone 1 gm Injection can increase the risk of adverse effects.

How to manage the interaction:
Taking Kefzone 1 gm Injection with Calcium gluconate is not recommended, but can be taken together if prescribed by a doctor. However, consult your doctor if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
CeftriaxoneCholera, live attenuated
Severe
How does the drug interact with Kefzone 1 gm Injection:
Taking the cholera vaccine after or along with Kefzone 1 gm Injection may reduce the activity of the vaccine.

How to manage the interaction:
Although taking Kefzone 1 gm Injection and Cholera, live attenuated together can evidently cause an interaction, it can be taken if your doctor has suggested it. To ensure adequate vaccine response, you should not receive cholera vaccine, live until at least 14 days after you complete your antibiotic therapy. In case you experience any unusual side effects, consult a doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Probiotics should be taken after taking the entire course of Kefzone 1 gm Injection 1's to restore some healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut, kombucha, and kimchi can help to restore the good bacteria of the intestine.
  • Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria, which helps stimulate their growth. Thus, fibre-rich foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains like whole-grain bread and brown rice should be included in your diet.
  • Avoid intake of alcoholic beverages with Kefzone 1 gm Injection 1's as it can make you dehydrated and may affect your sleep. This can make it harder for your body to aid the Kefzone 1 gm Injection 1's in fighting off infections.

Habit Forming

No

Therapeutic Class

ANTI- BACTERIALS

Kefzone 1 gm Injection 1's Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

Avoid consuming alcohol while taking Kefzone 1 gm Injection 1's as it causes increased side effects.

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Pregnancy

Consult your doctor

Please consult your doctor if you are pregnant, your doctor will prescribe Kefzone 1 gm Injection 1's only if the benefits outweigh the risks.

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Breast Feeding

Caution

A small amount of Kefzone 1 gm Injection 1's may pass into breast milk. Avoid taking Kefzone 1 gm Injection 1's if you are breastfeeding unless prescribed.

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Driving

Caution

Kefzone 1 gm Injection 1's may cause dizziness in some people, so it may affect your ability to drive.

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Liver

Consult your doctor

Dose adjustment may be needed. Please consult your doctor before taking Kefzone 1 gm Injection 1's if you have liver impairment/liver disease.

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Kidney

Consult your doctor

Dose adjustment may be needed. Please consult your doctor if you have any concerns regarding this or if you have kidney impairment/kidney disease before taking Kefzone 1 gm Injection 1's.

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Children

Safe if prescribed

For children, Kefzone 1 gm Injection 1's is safe if prescribed by the doctor. Consult your doctor for more infoemation.

Have a query?

FAQs

Kefzone 1 gm Injection 1's is used to treat various bacterial infections, such as respiratory tract (lungs) infections, urine infections, blood infections, meningitis (inflammation of the brain and spinal cord), gonorrhoea (sexually transmitted disease), and skin, abdominal, bone, and joint infections.

Kefzone 1 gm Injection 1's is an antibiotic that contains Cefoperazone (cephalosporin antibiotic). Kefzone 1 gm Injection 1's works by preventing the formation of bacterial cell covering, which is necessary for their survival by binding to the penicillin-binding proteins (PBPs), thus preventing cross-linking of nascent peptidoglycan and kills the bacteria. Thereby, Kefzone 1 gm Injection 1's helps to treat bacterial infections.

Inform your doctor if you do not feel better even after finishing the full course of treatment. You must also inform your doctor if the symptoms get worse while using this medicine.

Usually, Kefzone 1 gm Injection 1's starts working soon after taking it. It may take a few days to kill all the dangerous bacteria and make you feel better.

Kefzone 1 gm Injection 1's may cause Clostridium difficile-associated diarrhoea (CDAD). Treatment with antibiotics alters the normal flora, leading to overgrowth of Clostridium difficile; this causes diarrhoea. Drink lots of fluids and eat fibre-rich food if you experience diarrhoea. If you find blood in your stools (tarry stools) or if you experience prolonged diarrhoea with abdominal pain, stop taking Kefzone 1 gm Injection 1's and consult your doctor. Do not take anti-diarrhoeal medicine on your own.

It's generally not recommended to consume alcohol while taking Kefzone 1 gm Injection 1's, as it can increase gastrointestinal issues, enhance sedative effects, and interfere with the antibiotic's effectiveness. Consult your doctor for personalized advice.

As Kefzone 1 gm Injection 1's is administered in a hospital by a healthcare provider, Therefore, the chances of missing a dose is less. However, if you have any concerns, contact your doctor. Do not self-administer.

Common side effects of Kefzone 1 gm Injection 1's include diarrhoea, allergic reactions, abnormal liver function tests, and anemia. Most of these side effects are temporary and resolve on their own. However, if they persist, consult your doctor for proper evaluation and guidance.

Country of origin

India

Manufacturer/Marketer address

14, Industrial Area Tilak Nagar, First Floor, Behind Subhash Nagar Metro Station, New Delhi, Delhi 110018
Other Info - KEF0138

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Reference

  1. https://go.drugbank.com/drugs/DB01329
  2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/050551s043lbl.pdf
  3. https://labeling.pfizer.com/ShowLabeling.aspx?id=14801#:~:text=Cefoperazone%20contains%2034%20mg%20sodium,The%20empirical%20formula%20is%20C25H26N9NaO8S2.
  4. https://www.mayoclinic.org/drugs-supplements/cefoperazone-intramuscular-route-intravenous-route/description/drg-20406573
  5. https://www.drugs.com/drug-interactions/cefoperazone-with-lasix-548-0-1146-676.html#:~:text=Interactions%20between%20your%20drugs&amp;text=Cephalosporin%20antibiotics%20like%20cefoperazone%20can,furosemide%20may%20increase%20that%20risk.

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