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  3. Kefex-O Tablet

Kefex-O Tablet, Pack of 10 TabletS
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Kefex-O Tablet is used to treat infections caused by bacteria including pneumonia, gonorrhoea (a sexually transmitted disease), typhoid fever, infectious diarrhoea, and infections of the skin, eye/ear, bone, joint, abdomen, and prostate (male reproductive gland). It contains Ofloxacin, which works by killing bacteria that cause infections and preventing the further spread of the infection. In some cases, you may experience sleep problems, headache, dizziness, nausea, vomiting, diarrhoea, itching, external genital itching in women, vaginal inflammation (vaginitis) and taste changes. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions. Do not take this medicine with dairy products as it may lower its efficacy.

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Composition :

OFLOXACIN-200MG

Manufacturer/Marketer :

Kad'lak Life Sciences India Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Kefex-O Tablet

Kefex-O Tablet is used to treat infections caused by bacteria, including pneumonia, gonorrhoea (a sexually transmitted disease), typhoid fever, infectious diarrhoea, and infections of the skin, eye/ear, bone, joint, abdomen, and prostate (male reproductive gland). A bacterial infection is a condition in which bacteria grow in the body and cause infection. It can target any body part and multiple very quickly. 

Kefex-O Tablet contains antibacterial Ofloxacin, which helps in treating and preventing a wide range of bacterial infections. It is bactericidal and works by killing bacteria that cause infections.  It inhibits the repairing of bacterial cells and kills the bacteria, thereby preventing the further spread of the infection. Kefex-O Tablet is a broad-spectrum antibiotic against most Gram-negative bacteria, many Gram-positive bacteria, and some anaerobes bacteria (which live without oxygen).

Kefex-O Tablet should be taken in the dose and duration as advised by your doctor. It is advised to be taken with food and taken at a fixed time to achieve maximum effect. Do not take Kefex-O Tablet with dairy products as it may lower its efficacy. You may experience sleep problems, headache, dizziness, nausea, vomiting, diarrhoea, itching, external genital itching in women, vaginal inflammation (vaginitis) and taste changes in some cases. Most of these side effects of Kefex-O Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor. If you experience any allergic reaction symptoms such as rashes, itching, swelling, or shortness of breath, immediately contact the doctor.

Inform your doctor if you have any lung disease, muscle weakness (myasthenia gravis), sleeping disorder or difficulty sleeping (sleep apnoea), severe liver disease, or problem with alcohol or other prescription recreational drugs. Inform your doctor if you are planning to get pregnant, are pregnant, or are breastfeeding. Use of Kefex-O Tablet is associated with an increased risk of tendinitis and tendon (tough tissue that connects muscle to bone) rupture in all ages. People taking Kefex-O Tablet who are over 60 years old are at high risk, especially those who are taking any anti-allergic medicines like corticosteroid drugs. Kefex-O Tablet is contraindicated in people with kidney/heart diseases, and for those who have had lung transplants, its use is not recommended.

Uses of Kefex-O Tablet

Kefex-O Tablet is used in the treatment of bacterial infections. The detailed uses of Kefex-O Tablet are as follows:<br/>• Bacterial Infections: Kefex-O Tablet is commonly prescribed to treat a wide range of bacterial infections, including respiratory tract infections, urinary tract infections, and skin infections.<br/>• Sexually Transmitted Infections: Kefex-O Tablet can be used to manage sexually transmitted diseases such as gonorrhea and chlamydia effectively.<br/>• Chronic Obstructive Pulmonary Disease (COPD): Kefex-O Tablet is helpful in treating acute bacterial exacerbations in patients with COPD, improving symptoms and aiding recovery.<br/>• Infectious Diarrhea: Kefex-O Tablet is also effective in treating infectious diarrhea caused by certain bacterial strains.<br/>

Directions for Use

• Kefex-O Tablet can be taken with or without food as advised by your doctor.• It should be taken once a day or as recommended by the doctor.• Swallow Kefex-O Tablet as a whole with a glass of water.• Do not chew, crush or break it.

Medicinal Benefits

Kefex-O Tablet contains the antibiotic Ofloxacin, which helps in treating and preventing a wide range of bacterial infections caused by most Gram-negative bacteria, many Gram-positive bacteria, and some anaerobes bacteria (that live without oxygen). It is bactericidal in nature and works by killing bacteria that cause infections by preventing the formation of the cell wall required for living. It also inhibits the repair of bacterial cells. Altogether it kills the bacteria. Kefex-O Tablet has the advantage of good penetration in most deep tissues and body fluids. Hence, it is also suitable for the treatment of deep tissue and bone bacterial infections.

How Kefex-O Tablet Works

Kefex-O Tablet contains antibacterial Ofloxacin, which helps in treating and preventing a wide range of bacterial infections. It is bactericidal and works by killing bacteria that cause infections.  It inhibits the repairing of bacterial cells and kills the bacteria, thereby preventing the further spread of the infection.

Storage

Keep Kefex-O Tablet out of the sight and reach of children.
Side effects of Kefex-O Tablet
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

What if I have taken an overdose of Kefex-O Tablet

Do not take more than the prescribed dose of Kefex-O Tablet as it may cause overdose. The symptoms of overdose include nausea, dizziness, slurred speech, confusion, hot and cold flushes or numbness and swelling of the face. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not take Kefex-O Tablet if you are allergic or have had a severe reaction to ofloxacin or any other quinolone or fluoroquinolone antibiotics such as delafloxacin, gemifloxacin, levofloxacin, moxifloxacin, and ciprofloxacin. Taking Kefex-O Tablet may increase the chances of developing tendinitis (swelling of a fibrous tissue that connects a bone to a muscle) or have a tendon rupture (tearing of a fibrous tissue that connects a bone to a muscle). Inform your doctor if you have or have ever had a kidney, heart, or lung transplant, kidney disease, a joint or tendon disorder such as rheumatoid arthritis (an autoimmune disorder of joints causing pain, swelling, and loss of function), seizures (fits), epilepsy or if you participate in regular physical activity. Taking Kefex-O Tablet may worsen muscle weakness in people with myasthenia gravis (a nervous system disorder that causes muscle weakness) and cause severe difficulty breathing or death. Dairy products should be avoided along with Kefex-O Tablet. And also, exposure to sunlight should be avoided while taking Kefex-O Tablet as it may cause increased phototoxicity or photosensitivity. Patients with epilepsy and irregular heartbeat (QT prolongation) should tell their doctor before taking Kefex-O Tablet.

Drug-Drug Interactions

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CefiximeCholera, live attenuated
Severe

Drug-Drug Interactions

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CefiximeCholera, live attenuated
Severe
How does the drug interact with Kefex-O Tablet:
Co-administration of Kefex-O Tablet with Cholera vaccine may reduce the effectiveness of the vaccine.

How to manage the interaction:
Talk to your doctor before receiving the cholera vaccine if you are currently being treated with Kefex-O Tablet or have been treated within the last 14 days. To ensure adequate vaccine response, you should not receive cholera vaccine until at least 14 days after you complete your antibiotic therapy. Do not discontinue the medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Do not drink or eat a lot of caffeine-containing products such as coffee, tea, energy drinks, cola, or chocolate. Kefex-O Tablet may increase nervousness, sleeplessness, and anxiety caused by caffeine.

  • Probiotics should be taken after taking the full course of Kefex-O Tablet to restore some healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhea. Certain fermented foods like yogurt, cheese, sauerkraut, kombucha, and kimchi can help restore the intestine's good bacteria. 

  • Include more fiber-enriched food in your diet, as it can be easily digested by your gut bacteria, which helps stimulate their growth. Thus, fiber-rich foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains like whole-grain bread, brown rice should be included in your diet. Make sure you drink plenty of water or other fluids every day while you are taking Kefex-O Tablet.

  • Avoid alcoholic beverages with Kefex-O Tablet as it can make you dehydrated and may affect your sleep. This can make it harder for your body to aid the Kefex-O Tablet in fighting off infections.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS

Kefex-O Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Alcohol is not known to cause any unpleasant side effects if taken along with Kefex-O Tablet. But intake of alcohol with Kefex-O Tablet may damage your liver. So intake of Kefex-O Tablet should be avoided with Kefex-O Tablet.

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Pregnancy

Unsafe

Kefex-O Tablet is a pregnancy Category C medicine. It is not known whether Kefex-O Tablet will affect pregnant women or fetus or not. Hence, the intake of Kefex-O Tablet should be avoided if you are pregnant or planning to become pregnant as it may harm the baby.

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Breast Feeding

Caution

Kefex-O Tablet is excreted in human milk. But the amount of Kefex-O Tablet absorbed by the nursing infant is unknown. So, it should not be taken while breastfeeding.

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Driving

Caution

Kefex-O Tablet can affect alertness and coordination. So, operating machinery which requires concentration should be avoided.

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Liver

Caution

Kefex-O Tablet to be taken with caution, especially if you have a history of liver diseases/conditions. Your doctor may have to adjust the dose if there are symptoms of nausea, vomiting, loss of appetite, dark-colored urine, yellowing of or skin/eye.

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Kidney

Caution

Kefex-O Tablet to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Safe if prescribed

Kefex-O Tablet can be given to children but under child specialist medical supervision. Kefex-O Tablet is prescribed to the children to treat complicated urinary tract infections, anthrax infection, or plague infection.

Have a query?

FAQs

Kefex-O Tablet is used to treat bacterial infections, including pneumonia, gonorrhoea (a sexually transmitted disease), typhoid fever, infectious diarrhoea, and infections of the skin, eye/ear, bone, joint, abdomen, and prostate (male reproductive gland).

If you miss a dose of Kefex-O Tablet, take the missed dose as soon as you remember it. However, if it&#039;s almost time for the next dose, do not take a double dose to make up for a missed one.

No, Kefex-O Tablet should not be taken along with dairy products as it might affect the absorption and efficacy of Kefex-O Tablet. However, you can take it with a meal that includes these foods or drinks.

Kefex-O Tablet makes your skin sensitive to sunlight known as photosensitivity. So, prolonged exposure to sunlight or ultraviolet light should be avoided. In case of emergency, you should always wear sunscreen before going out.

Yes, after taking Kefex-O Tablet, you may have diarrhea. Kefex-O Tablet is an antibiotic that kills or prevents bacterial growth, so in case some good intestinal bacteria which aid in digestion might also get killed. So, drink plenty of fluids and take probiotics to prevent excessive loss of fluids from the body (dehydration).

No, Kefex-O Tablet should be taken in the dose and duration as advised by the doctor. If you take it in more than the recommended dose, it might cause unpleasant side effects. If you think your symptoms are not improving, please consult your doctor

You are recommended to take Kefex-O Tablet either 2 hours before or 2 hours after taking an antacid, multivitamin, or other product that has calcium/magnesium/aluminium/iron/zinc, antiulcer agent (sucralfate) or anti-HIV drug (didanosine).

Country of origin

India

Manufacturer/Marketer address

H.No. 5-5-35/39,Prasanthi Nagar, IDA Kukatpally, Hyderabad Hyderabad TG 500072 IN
Other Info - KEF0105

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:34 AM IST

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Reference

  1. https://medlineplus.gov/druginfo/meds/a691005.html
  2. https://www.drugs.com/mtm/ofloxacin.html
  3. https://www.gov.uk/drug-safety-update/fluoroquinolone-antibiotics-new-restrictions-and-precautions-for-use-due-to-very-rare-reports-of-disabling-and-potentially-long-lasting-or-irreversible-side-effects

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