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KABIROC 5ML INJECTION is used for Skeletal muscle relaxation during surgery or other medical procedures. It contains Rocuronium bromide. It relaxes the muscles by blocking the impulses from the nerves. Thus, it is easy to aid surgical procedures and ventilation of the lungs in elective and critical situations. Transient hypotension, hypertension, and feeling tired, weak, or dizzy are undesirable consequences during your procedure, just like other general anaesthetics, since your anaesthetist will immediately address any issues that emerge during your procedure.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Fresenius Kabi India Pvt Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About KABIROC 5ML INJECTION

KABIROC 5ML INJECTION is a specialised prescription injection used to temporarily relax muscles during surgical procedures or when a patient is on a breathing machine (ventilator) in intensive care. It helps relax the throat and vocal cords so a breathing tube can be inserted safely and easily before surgery.

Because of its specific medical purpose, this medicine is not for regular daily use. It is administered as a single injection or a continuous intravenous drip only when a patient is undergoing a procedure. No diet or lifestyle changes can replace its medical action, but resting after your procedure helps your muscles recover their strength faster.

While this medicine is highly effective under professional care, some patients may experience temporary muscle weakness, dizziness, or changes in blood pressure. It is important to inform your medical team immediately if you feel prolonged weakness or breathing difficulties as you wake up from anaesthesia.

Before undergoing any procedure involving this medicine, tell your doctor if you have neuromuscular disorders, liver damage, or kidney problems. You must not receive this medicine if you have a known history of severe allergic reactions to KABIROC 5ML INJECTION, other muscle relaxants, or bromides.

This medicine can interact with certain antibiotics and anaesthetics, which may prolong its muscle-relaxing effects. If you are pregnant, breastfeeding, or an elderly individual, your medical team will carefully adjust your care to ensure safety.

Uses of KABIROC 5ML INJECTION

KABIROC 5ML INJECTION is used during surgical procedures and intensive care to provide temporary muscle relaxation. The detailed uses of KABIROC 5ML INJECTION are as follows:

  • Skeletal muscle relaxation: It relaxes your body's muscles to prevent involuntary movements, allowing surgeons to perform delicate surgical procedures safely.
  • Facilitating mechanical ventilation: It relaxes the airway and chest muscles so that a breathing machine can support your lungs without resistance.
  • Tracheal intubation and Rapid Sequence Induction (RSI): It rapidly relaxes the throat muscles, enabling fast and safe insertion of a breathing tube during planned surgical procedures or emergency airway management (RSI).

Key Benefits

KABIROC 5ML INJECTION provides critical physical support during major surgeries and intensive care by producing controlled muscle relaxation. The detailed benefits of KABIROC 5ML INJECTION are as follows:

  • Surgical Support: By keeping the skeletal muscles completely relaxed, it ensures that surgical procedures can be carried out with the highest level of precision and safety, minimising physical stress on your body.
  • Ventilator Support: For patients in intensive care, it helps ease the discomfort of being connected to a ventilator. This allows the breathing machine to work in perfect harmony with the body, ensuring steady oxygen levels and allowing the lungs to heal with minimal effort.
Side effects of Kabiroc 5ml Injection
  • If you experience or encounter any severe allergic reaction, stop using medication and consult the doctor right away.
  • Tell your doctor about the allergic reaction, including the medication taken and any symptoms experienced.
  • Your doctor will evaluate the severity of the reaction and determine the best course of action.
  • To ensure a full recovery, follow your doctor's advice, attend scheduled follow-up appointments, and undergo recommended tests to monitor progress and adjust treatment as needed.
  • Physical therapy (includes strength and range of motion exercises) and occupational therapy (focuses on helping you live your everyday life with more comfort) may help in the treatment of myopathy.
  • Consult your doctor for medications to reduce inflammation, improve muscle function or treat underlying infections or conditions.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safety.
  • KABIROC 5ML INJECTION will be given to you by your anaesthetist in a hospital setting.
  • Do not self-administer.

How KABIROC 5ML INJECTION Works

KABIROC 5ML INJECTION contains rocuronium bromide, which temporarily blocks the chemical signals that travel between your nerves and your muscles. Under normal conditions, your nerves release a chemical messenger that binds to muscle receptors, telling the muscles to contract and move. KABIROC 5ML INJECTION attaches itself to these exact muscle receptors, acting like a shield. By blocking the chemical messenger from landing, it prevents the muscle from contracting, resulting in temporary and controlled muscle relaxation. The effect naturally wears off as the body processes and clears the medicine.
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption.

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Pregnancy

Caution

KABIROC 5ML INJECTION should be used in pregnant women only if clinically needed, and the benefits outweigh the risks. So, inform your doctor before receiving the KABIROC 5ML INJECTION if you are pregnant or planning for pregnancy. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Avoid breastfeeding for a certain period (at least 6 hours) after receiving a Rocuronium bromide injection as per the doctor's instructions.

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Driving

Unsafe

Patients should not drive or operate heavy machinery for a certain period of time. When rocuronium bromide is administered as part of a general anaesthetic, you may feel tired, weak, or dizzy for a short period of time. Your anesthesiologist can tell you how long the effects will remain.

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Liver

Caution

Caution should be exercised while using KABIROC 5ML INJECTION in patients with liver impairment. So, inform your doctor before receiving the KABIROC 5ML INJECTION if you have a liver impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Caution should be exercised while using KABIROC 5ML INJECTION in patients with Kidney impairment. So, inform your doctor before receiving the KABIROC 5ML INJECTION if you have a Kidney impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Safe if prescribed

KABIROC 5ML INJECTION can be used in children (newborns and adolescents).

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Heart

Caution

If you have a pre-existing or a history of heart disease, inform your doctor before receiving KABIROC 5ML INJECTION. Your doctor will weigh the benefits and potential risks before prescribing this medicine.

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Geriatrics

Consult your doctor

Please consult a doctor if you have any concerns regarding the use of KABIROC 5ML INJECTION in elderly patients.

What if I have taken an overdose of KABIROC 5ML INJECTION

In the highly unlikely event of an overdose in a clinical setting, healthcare professionals are fully trained to manage it immediately. They will support your breathing mechanically and may inject a specific reversal agent, such as sugammadex or neostigmine, to quickly restore normal muscle function.

Diet & Lifestyle Advise

  • Rest After the Procedure: Rest quietly for the first 24 hours after your procedure to give your muscles ample time to recover their strength and coordination.
  • Stay Hydrated: Drink plenty of water to help your kidneys flush the remaining medicine out of your system safely.
  • Avoid Strenuous Activities: Avoid lifting heavy weights, climbing ladders, or performing strenuous physical tasks until your doctor confirms your muscles have fully recovered.
  • Eat Light Meals: Eat light, soft, and easily digestible meals after your surgery to prevent nausea or stomach discomfort as your digestive system recovers from anaesthesia.
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How Soon It Starts Working

The time required for KABIROC 5ML INJECTION to start to work: KABIROC 5ML INJECTION shows its rapid action after the IV administration. The time for which the effects of KABIROC 5ML INJECTION last: The peak effect of KABIROC 5ML INJECTION lasts for a few hours.

What if you forget to take KABIROC 5ML INJECTION

Since this medicine is given only by medical experts during surgery or in an intensive care unit, a missed dose is not possible.

Storage

• In clinical settings, KABIROC 5ML INJECTION must be stored in a refrigerator at temperatures between 2°C and 8°C (36°F to 46°F) to ensure its stability.
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Keep Refrigerated. Do not freeze.Prepaid payment required.

Drug Warnings

  • Inspect the Solution: Confirm that your medical team inspects the solution before administration; it must be completely clear, colourless, and free of any visible particles.
  • Continuous Monitoring: Ensure that your breathing, oxygen levels, heart rate, and nerve-muscle depth (using nerve stimulation tools like Train-of-Four monitoring) are tracked continuously by a healthcare professional while this medicine is active.
  • Inform Your Anaesthesiologist: Tell your anaesthesiologist if you or anyone in your family has ever had a severe reaction to anaesthesia, such as a sudden high fever (malignant hyperthermia).
  • Avoid Driving: Do not drive, operate machinery, or make important decisions for at least 24 hours after receiving this injection, as your reflexes may be temporarily slowed.

Drug-Drug Interactions

verifiedApollotooltip
  • Certain antibiotics (such as aminoglycosides): May increase the muscle-relaxing effects of KABIROC 5ML INJECTION, potentially delaying the recovery of your muscle strength.
  • Inhaled anaesthetics: Can enhance and prolong the muscle-relaxing effects of this medicine during surgery.
  • Magnesium salts: May increase the depth and duration of muscle relaxation.
  • Corticosteroids: Long-term concurrent use alongside muscle relaxants in intensive care settings can increase the risk of prolonged muscle weakness (steroid-induced myopathy). 

Drug-Drug Interactions

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How does the drug interact with Kabiroc 5ml Injection:
When Rocuronium is used with Gentamicin, it can make the treatment more effective.

How to manage the interaction:
Co-administration of Kabiroc 5ml Injection with Gentamicin can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Kabiroc 5ml Injection:
Co-administration of amikacin with Kabiroc 5ml Injection enhances the effects of Kabiroc 5ml Injection leading to the risk of breathing problems.

How to manage the interaction:
Taking Kabiroc 5ml Injection with Amikacin together can result in an interaction, but it can be taken if your doctor has advised it. Consult your doctor if you experience shortness of breath, chest pain, or palpitation. Do not stop using any medications without a doctor's advice.
How does the drug interact with Kabiroc 5ml Injection:
Coadministration of Kabiroc 5ml Injection with Colistin may increase the side effects of Kabiroc 5ml Injection.

How to manage the interaction:
Although there is a possible interaction between Colistin and Kabiroc 5ml Injection, you can take these medicines together if prescribed by your doctor. However, if you experience an upset stomach, Rash, Dizziness, or Fever, consult a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Kabiroc 5ml Injection:
Coadministration of Kabiroc 5ml Injection with Streptomycin may increase the risk or severity of developing hearing loss, breathing problems, and kidney problems.

How to manage the interaction:
There may be a possibility of interaction between Kabiroc 5ml Injection and Streptomycin, but it can be taken if prescribed by a doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, swelling, increased or decreased urination, body aches, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • No clinically significant food interactions are known with KABIROC 5ML INJECTION when used as directed.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[MUSCLE RELAXANTS]

FAQs

KABIROC 5ML INJECTION is used for Skeletal muscle relaxation during surgery or other medical procedures.
KABIROC 5ML INJECTION contains Rocuronium bromide. It relaxes the muscles by blocking the impulses from the nerves. Thus, it is easy to aid surgical procedures and ventilation of the lungs in elective and critical situations.
You should not receive Rocuronium bromide if you are allergic to rocuronium or any of the other ingredients of this medicine.
You are typically given a sedative or general anaesthetic before this medicine is injected, meaning you will be asleep and will not feel any pain. Talk to your doctor to learn more about your procedure.
The muscle-relaxing effects generally last between 30 and 45 minutes, though this can vary depending on your dose and overall health. Talk to your doctor if you have concerns about your recovery timeline.
Yes, if needed, doctors can inject specific reversal medicines, most notably sugammadex (Bridion), to rapidly restore muscle function and strength. Talk to your doctor or anaesthesiologist for more details.
No, this medicine is strictly for hospital use and must only be administered by trained medical specialists in a controlled clinical environment. Talk to your doctor if you have questions about where your procedure will take place.
It is typically used during pregnancy only if the medical benefits clearly outweigh the potential risks, such as during an emergency caesarean section. Talk to your doctor if you are pregnant or breastfeeding.
It can occasionally cause minor, temporary changes in heart rate or blood pressure, which your medical team will monitor closely during the procedure. Talk to your doctor if you have a history of heart issues.
It is normal for your muscles to feel slightly weak or heavy as the effects of the muscle relaxant and anaesthesia gradually wear off. Talk to your doctor if this weakness persists or becomes concerning.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Fresenius Kabi AG? , Else-Kröner-Straße 1 ? , 61352 Bad Homburg , Germany
Other Info - KAB0027
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