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compositionComposition:DICLOFENAC-100MG
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Prescription Medicine
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Jonac Suppositories is used to relieve pain and inflammation. It contains Diclofenac, which works by blocking the chemical messengers that cause pain and swelling. In some cases, this medicine may cause side effects like nausea, vomiting, diarrhoea, heartburn and stomach pain. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

DICLOFENAC-100MG

Manufacturer/Marketer :

German Remedies Ltd

Consume Type :

Rectal

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Jonac Suppositories

Jonac Suppositories is a rectal suppository designed to relieve pain, swelling, and stiffness caused by painful joint and muscle conditions. It is commonly prescribed to manage symptoms of long-term inflammatory issues like arthritis, as well as sudden, painful flare-ups such as gout or post-surgical pain. By delivering the active medicine directly through the rectum, it offers an effective alternative for patients who cannot swallow tablets.

To get the most benefit, it is important to use this medicine consistently and at the exact times recommended by your doctor. Because of its design, this medicine is strictly for rectal use and must never be taken by mouth. Emptying your bowels before inserting the suppository can help it work more effectively. Combining this treatment with gentle joint movements and maintaining a healthy weight can also help ease joint strain.

While using Jonac Suppositories, some people may experience mild, temporary local irritation in the back passage or feel a temporary urge to pass stools. Most people tolerate this medicine well, but you must contact your doctor immediately if you notice serious symptoms such as bleeding from your back passage, severe stomach pain, or black, tarry stools.

Do not take this if you have an active stomach ulcer, severe heart failure, or a history of allergic reactions or asthma attacks triggered by other pain relievers. Before starting this treatment, always tell your doctor if you have high blood pressure, kidney disease, liver disease, or inflammatory bowel conditions.

This medicine can interact with other treatments like blood thinners and other oral pain relievers, while smoking or drinking alcohol can increase your risk of stomach bleeding. If you are pregnant, planning a pregnancy, breastfeeding, or are an older adult, you should consult your doctor before using Jonac Suppositories to ensure it is safe for you.

Uses of Jonac Suppositories

Jonac Suppositories is used in the treatment of pain and inflammation. The detailed uses of Jonac Suppositories are as follows:

  • Rheumatoid arthritis: Jonac Suppositories helps by reducing the painful joint swelling, stiffness, and inflammation associated with this chronic autoimmune condition.
  • Osteoarthritis: It targets pain and inflammation in wear-and-tear joint disease, allowing for improved physical mobility.
  • Ankylosing spondylitis: It relieves severe back pain and stiffness in this chronic spinal arthritis, helping you stay active.
  • Acute gout attacks: It quickly eases the intense, sudden joint pain and swelling caused by uric acid crystal buildup.
  • Post-operative pain: It provides effective pain relief after surgeries, especially when swallowing oral medication is difficult or not recommended.

Key Benefits

Jonac Suppositories provides pain relief and reduces stiffness, with rectal administration offering an alternative for patients who cannot take oral medicines.

The following are the benefits of this medication:

  • Provides an option for patients experiencing severe nausea or who are unable to swallow oral medicines.
  • Can be used when oral intake is restricted, such as during recovery from surgery.
  • Provides reliable and prolonged relief from constant pain and stiffness.
  • Helps improve pain-free movement and comfort during daily activities.
  • May reduce direct, immediate irritation to the stomach lining compared with oral pain relievers.
Side effects of Jonac Suppositories
  • Limit processed foods and eat more vegetables and fruits.
  • Exercise at least 30 minutes every day.
  • Maintain a healthy weight.
  • Quit smoking as it can worsen kidney damage.
  • Control your blood pressure and blood glucose.
  • Limit salt intake and alcohol consumption.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the steps to manage the medication-triggered Sinusitis (Sinus infection or Inflammation Of Sinuses):
  • Consult your doctor if you experience symptoms of sinusitis, such as nasal congestion, facial pain, or headaches, which may be triggered by your medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your sinusitis symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • If your doctor advises, you can use nasal decongestants or saline nasal sprays to help relieve nasal congestion and sinus pressure.
  • To help your body recover, get plenty of rest, stay hydrated, and engage in stress-reducing activities. If your symptoms persist or worsen, consult your doctor for further guidance.
Here are the steps to manage the medication-triggered Upper respiratory tract infection:
  • Inform your doctor about the symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids to help loosen and clear mucus from your nose, throat, and airways.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
Managing Medication-Triggered Bronchitis (Inflammation of the bronchial tubes): A Step-by-Step Guide:
  • If you experience symptoms like coughing, wheezing, chest tightness, or difficulty breathing after taking medication, seek medical attention immediately.
  • Your healthcare provider will work with you to stop the medication causing the reaction, start alternative treatments, and provide supportive therapy.
  • To manage symptoms and prevent complications, follow your doctor's advice to use inhalers or nebulizers as prescribed, practice good hygiene, avoid irritants, stay hydrated, and get plenty of rest.
  • Regularly track your symptoms and report any changes or concerns to your healthcare provider.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Check the label for directions before using Jonac Suppositories.
  • Empty your bowels before inserting the suppository. Lie on one side with your knees pulled up towards your chest. Remove the wrapper and insert the pointed end of the suppository into the rectum. Push the suppository as far as possible.
  • Wash your hands thoroughly before and after use.
  • Try not to empty your bowels for at least an hour after using Jonac Suppositories.

How Jonac Suppositories Works

Jonac Suppositories contains diclofenac, which belongs to a group of medicines called nonsteroidal anti-inflammatory drugs (NSAIDs). When your body experiences injury or inflammation, it produces chemical messengers called prostaglandins, which cause pain and swelling. This medicine works by blocking the specific enzymes (known as cyclooxygenase or COX enzymes) that are responsible for producing these prostaglandins. By stopping these chemicals at their source, Jonac Suppositories significantly lowers swelling, redness, and pain in the affected tissues, helping you feel much more comfortable.
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Alcohol

Unsafe

Avoid consumption of alcohol as it may increase the risk of gastrointestinal side effects.

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Pregnancy

Consult your doctor

Diclofenac should be used during the first 6 months of pregnancy only if necessary and advised by your doctor. It is not recommended for use in the last 3 months of pregnancy as it may harm the unborn child or cause problems at delivery. Hence, if you are pregnant or planning pregnancy, consult your doctor before starting Jonac Suppositories.

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Breast Feeding

Consult your doctor

Please consult the doctor if you are breastfeeding. Diclofenac should be avoided during lactation as it may pass into breast milk and cause undesirable effects in the infant.

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Driving

Caution

Occasionally, Jonac Suppositories may cause dizziness. Drive or operate machinery only if you are alert.

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Liver

Consult your doctor

Jonac Suppositories is not recommended if you have liver failure. Please consult the doctor if you have liver problems.

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Kidney

Consult your doctor

Jonac Suppositories is not recommended if you have kidney failure. Please consult the doctor if you have kidney problems.

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Children

Unsafe

Please consult the doctor. The doctor will determine the appropriate dose for use in children.

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Heart

Caution

Please inform your doctor if you have heart problems before using Jonac Suppositories, as it is contraindicated in patients with conditions like ischemic heart disease, stroke history, or congestive heart failure.

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Geriatrics

Consult your doctor

Please inform your doctor if you are geriatric before using Jonac Suppositories, as older adults are more prone to side effects like gastrointestinal bleeding and cardiovascular risks. Medical supervision is essential to ensure the lowest effective dose and safe use.

What if I have taken an overdose of Jonac Suppositories

If you accidentally use too many suppositories or if someone, especially a child, swallows one, seek immediate medical attention or contact a poison control centre right away.

Diet & Lifestyle Advise

  • Stay well hydrated: Drink plenty of water throughout the day to support healthy kidney function while using this medicine.
  • Choose fibre-rich foods: Include plenty of fruits, vegetables, and whole grains in your diet to help prevent constipation and make rectal administration more comfortable.
  • Choose low-impact exercise: Activities such as walking or swimming can help keep your joints flexible and strong without placing excessive stress on them.
  • Avoid smoking and alcohol: Avoid smoking and limit alcohol intake, as both can increase the risk of stomach or intestinal irritation and bleeding when taking NSAIDs.
health query

Have a query?

How Soon It Starts Working

  • The time required for Jonac Suppositories to start to work: Jonac Suppositories ideally shows its action within 1 hour after administration.
  • The time for which the effects of Jonac Suppositories last: The effect of Jonac Suppositories lasts for 8 hours.

What if you forget to take Jonac Suppositories

If you miss a dose, use it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and continue with your regular schedule. Do not use a double dose to make up for a missed one.

Storage

• Store Jonac Suppositories suppositories in a cool, dry place where the temperature stays below 25°C.

Drug Warnings

  • Check the suppository before use: Make sure the suppository is firm before inserting it. If it feels soft, chill it in the refrigerator while it is still in the wrapper until it becomes firm.
  • Do not cut the suppository: Use the suppository whole and do not cut or divide it. Dividing it may result in an uneven amount of medicine in each part.
  • Use only in the rectum: This medicine is meant for rectal use only. Do not swallow it or use it in any other way.
  • Avoid other NSAID painkillers: Do not take other oral NSAID painkillers, such as ibuprofen or naproxen, while using this medicine unless your doctor specifically tells you to. Taking them together can increase the risk of side effects.
  • Watch for dark stools: Check your stools for any unusual dark or tar-like appearance. Contact your doctor immediately if you notice this, as it may be a sign of bleeding in the digestive tract.
  • Be careful when driving: This medicine may sometimes cause dizziness or sleepiness. Avoid driving or operating machinery if you experience these effects.

Drug-Drug Interactions

verifiedApollotooltip
  • Blood thinners (e.g., warfarin): May significantly increase the risk of serious stomach and rectal bleeding.
  • Other NSAIDs (e.g., ibuprofen, aspirin): May increase the risk of stomach ulcers and digestive side effects.
  • Blood pressure medicines (e.g., lisinopril, furosemide): May reduce the effectiveness of your blood pressure medicine and increase the risk of kidney damage.
  • Mood stabilisers (e.g., lithium): May increase lithium levels in your blood to dangerous levels.
DiclofenacMeloxicam
Critical
DiclofenacDeferasirox
Severe

Drug-Drug Interactions

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DiclofenacMeloxicam
Critical
How does the drug interact with Jonac Suppositories:
Co-administration of Jonac Suppositories with Meloxicam can increase the risk or severity of gastrointestinal side effects.

How to manage the interaction:
Taking Meloxicam with Jonac Suppositories is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medication without doctor's advise.
DiclofenacDeferasirox
Severe
How does the drug interact with Jonac Suppositories:
Co-administration of Jonac Suppositories and deferasirox may increase your risk of developing stomach bleeding.

How to manage the interaction:
There may be a possible interaction between Jonac Suppositories and deferasirox but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience symptoms such as severe abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, and/or black, tarry stools, increased or decreased urination, fluid retention, swelling, shortness of breath, muscle cramps, weakness, confusion, and irregular heart rhythm. Do not stop using any medications without first talking to your doctor.
DiclofenacEnoxaparin
Severe
How does the drug interact with Jonac Suppositories:
Taking Jonac Suppositories with Enoxaparin can increase the risk of bleeding complications.

How to manage the interaction:
There may be a possible interaction between Jonac Suppositories and Enoxaparin, but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience any unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Do not discontinue any medications without consulting a doctor.
DiclofenacFurosemide
Severe
How does the drug interact with Jonac Suppositories:
Concomitant administration of Jonac Suppositories and furosemide may decrease the therapeutic efficacy of furosemide and adversely affect renal function.

How to manage the interaction:
There may be a possible interaction between Jonac Suppositories and furosemide, but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience symptoms like nausea, dizziness, irregular heartbeats, altered blood pressure, tingling. Do not stop using any medications without first talking to your doctor.
DiclofenacKetorolac
Severe
How does the drug interact with Jonac Suppositories:
Coadministration of Jonac Suppositories and Ketorolac can increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding and ulceration.

How to manage the interaction:
Co-administration of Jonac Suppositories and Ketorolac can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
DiclofenacNaproxen
Severe
How does the drug interact with Jonac Suppositories:
Coadministration of Jonac Suppositories and Naproxen can increase the risk or severity of side effects.

How to manage the interaction:
Taking Jonac Suppositories and Naproxen together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
DiclofenacKetoconazole
Severe
How does the drug interact with Jonac Suppositories:
Coadministration of Jonac Suppositories with Ketoconazole may increase the risk of liver problems.

How to manage the interaction:
There may be a possible interaction between Jonac Suppositories and Ketoconazole, but they can be taken together if a doctor has prescribed them. However, consult a doctor immediately if you have fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark colored urine, light colored stools, and/or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
DiclofenacCidofovir
Severe
How does the drug interact with Jonac Suppositories:
Coadministration of Jonac Suppositories with cidofovir may increase the risk of kidney problems.

How to manage the interaction:
Although taking Jonac Suppositories and cidofovir together can possibly cause an interaction, it can be taken if your doctor has suggested it. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
DiclofenacFondaparinux
Severe
How does the drug interact with Jonac Suppositories:
Coadministration of Jonac Suppositories with fondaparinux may increase the risk of bleeding.

How to manage the interaction:
There may be a possible interaction between Jonac Suppositories and Fondaparinux when taken together, but they can be taken together if your doctor has prescribed them. However, if you experience bleeding, severe back pain, dizziness, black or red stools, severe headache, weakness, and vomiting contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
DiclofenacTacrolimus
Severe
How does the drug interact with Jonac Suppositories:
Co-administration of Jonac Suppositories with tacrolimus may cause kidney problems.

How to manage the interaction:
Co-administration of Jonac Suppositories and Tacrolimus can lead to an interaction, it can be taken if advised by your doctor. However, consult your doctor if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
  • No clinically relevant food interactions were found.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[NON-STEROIDAL DRUG, ANTI- INFLAMMATORY AGENTS]

FAQs

Jonac Suppositories is used to relieve pain and inflammation in conditions affecting joints, tendons and muscles.
Jonac Suppositories works by inhibiting the synthesis of certain chemical messengers that cause pain and inflammation. Thereby, Jonac Suppositories helps provide relief from pain.
Jonac Suppositories might make it more difficult to conceive. Please consult the doctor if you have concerns regarding this.
It is advised to use the lowest effective dose for the shortest durations. However, use Jonac Suppositories for as long as it has been recommended by the doctor.
No, Jonac Suppositories suppositories are strictly designed for rectal use only. Swallowing them can cause severe throat irritation and will not work as intended. If you cannot use them rectally, talk to your doctor for an alternative.
This medicine is absorbed relatively quickly through the rectal lining. Many patients begin to feel relief from pain and stiffness within 30 minutes to an hour after insertion. Talk to your doctor if your pain does not improve.
You should avoid using this medicine during pregnancy, especially during the last three months, as it can harm the unborn baby or cause complications during delivery. Always talk to your doctor before using any medication while pregnant.
It is highly recommended to limit or avoid alcohol. Combining alcohol with this type of medicine increases the risk of stomach irritation, bleeding, and ulcers. Talk to your doctor or pharmacist if you have concerns.
If it feels soft, keep it in its foil or plastic wrapper and hold it under cold running water or place it in the refrigerator for a few minutes. It will harden quickly and be ready for use.
Taking these two medications together can greatly increase your risk of stomach ulcers and bleeding. You must talk to your doctor before combining them, as they will need to evaluate your safety.
If you use this medicine for a long period, your doctor may check your kidney function, liver function, and blood counts to ensure the medicine is not causing undetected strain on your body. Talk to your doctor to learn more.
Yes, some people may feel dizzy or sleepy after using this medicine. Avoid driving, riding a bike, or operating heavy machinery until you know how this medicine affects you. Talk to your doctor if this symptom persists.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Electronic Medicines Compendium (EMC). Pil.1044 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  2. Electronic Medicines Compendium (EMC). Pil.5750 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  3. Drugs.com Clinical Review Team. Voltarol Suppositories 12 5Mg Leaflet Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  4. Diclofenac Diclofenac. 1998. [Accessed on 02 Apr. 2019]Check here
  5. Diclofenac sodium [Prescribing Information]. 2021. [Accessed on 06 Apr. 2024]Check here
  6. Cipla Limited. REACTIN® 100 SR Tablets – Product Information [Internet]. Mumbai: Cipla Limited; [Accessed on 2025 Sep 17]Check here
  7. Dexcel Pharma Ltd. Electronic Medicines Compendium (EMC). [Revised in March 2022] [Accessed on 29th July 2024]Check here

Country of origin

India

Manufacturer/Marketer address

Zydus Tower, Satellite Cross Roads, Ahmedabad – 380015, Gujarat, India.
Other Info - JON0011

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