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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Jbmune 500 Tablet is used to prevent the body from rejecting a transplanted organ, such as a kidney, heart, or liver. It contains Mycophenolate mofetil, which suppresses the immune system, allowing the transplanted graft to avoid rejection. This medicine may cause common side effects such as diarrhoea, vomiting, decreased white blood cell and red blood cell count, and infections. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and any pre-existing medical conditions.

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Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About Jbmune 500 Tablet

Jbmune 500 Tablet belongs to a class of medications called immunosuppressants used to prevent the body from rejecting a transplanted organ, such as a kidney, heart, or liver.

Jbmune 500 Tablet contains ‘Mycophenolate mofetil’, which works by suppressing the immune system, allowing the transplanted graft to avoid rejection.

The common side effects of Jbmune 500 Tablet are diarrhoea, vomiting, nausea, and headache. Most of these side effects do not require medical attention and resolve gradually over time. However, consult your doctor if any of these side effects persist or worsen.

Do not take Jbmune 500 Tablet if you are allergic to any of its ingredients, are pregnant, or breastfeeding. Avoid donating blood or sperm without informing your doctor. Please do not take any vaccinations as they may be less effective.

Uses of Jbmune 500 Tablet

Jbmune 500 Tablet is used in the prevention of organ transplant rejection. The detailed uses of Jbmune 500 Tablet are as follows:

  • Prevention of Organ Rejection: Jbmune 500 Tablet is used along with other immunosuppressants (such as corticosteroids and cyclosporine) to prevent the body from rejecting transplanted organs like the kidney, heart, or liver.
  • Steroid-Sparing Agent: In some cases, Mycophenolate is used in combination with or as an alternative to corticosteroids to reduce the long-term side effects of steroid treatment in autoimmune conditions.

Directions for Use

  • Jbmune 500 Tablet should be taken on an empty stomach, at least 1 hour or 2 hours after a meal or as directed by the doctor.
  • It is usually taken twice daily at the same time each day or as prescribed by your doctor.
  • Swallow Jbmune 500 Tablet as a whole with a glass of water.
  • Do not crush, chew, break it.

Medicinal Benefits

  • Jbmune 500 Tablet contains Mycophenolate mofetil, an immunosuppressant used primarily in organ transplant recipients.
  • It helps the body accept transplanted organs (like the kidney, heart, or liver) by suppressing immune responses.
  • Jbmune 500 Tablet inhibits the function of white blood cells (T and B lymphocytes), which are responsible for attacking transplanted organs.
  • It enhances the long-term success of organ transplantation.
  • Jbmune 500 Tablet is often used along with other immunosuppressants like tacrolimus or cyclosporine for optimal effect.
  • Preferred over long-term use of corticosteroids due to fewer chronic side effects.

How Jbmune 500 Tablet Works

Jbmune 500 Tablet contains Mycophenolate mofetil, which works by suppressing the immune system, allowing the transplanted graft to avoid rejection.

Storage

• Store in a cool and dry place away from sunlight.
• Keep Jbmune 500 Tablet out of the sight and reach of children.
• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Jbmune 500 Tablet
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Boost your immunity by including immune rich foods in your diet and always remember to stay hydrated.
  • Get sufficient sleep and manage stress which helps in improving white blood cell count.
  • Consult your doctor for an effective treatment to improve the blood cell count and get regular body check up to monitor changes in the count.
  • Try to prevent the factors that cause a decrease in white blood cells which may lead to impaired immunity.
  • Stay hydrated to support kidney and bladder health.
  • Rest on your back as advised by your doctor.
  • Limit physical strain for 1-2 weeks.
  • Avoid strenuous activities like running and contact sports.
  • Quit smoking to improve overall health.
  • Use pain medication responsibly.
  • Avoid foods that can irritate the urinary track, such as spicy or acidic foods.
  • Remember to consult your doctor for personalized advice and guidance on managing your symptoms and developing a treatment plan.
  • High levels of phosphate in the blood need immediate medical attention.
  • Get a physical examination and blood tests to identify factors causing high phosphate levels to manage the outcomes.
  • Avoid consuming phosphate rich foods like egg yolks, soft drinks, milk, chocolate etc.
  • Talk to your dietician and consume foods which can maintain ideal phosphorus levels.
  • Maintain a healthy weight and implement good habits to prevent stress and anxiety.

What if I have taken an overdose of Jbmune 500 Tablet

Do not take more than the prescribed dose of Jbmune 500 Tablet , as it may cause an overdose. Symptoms of an overdose include nausea, vomiting, stomach pain, diarrhoea, heartburn, fever, chills, or sore throat. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

  • Do not take Jbmune 500 Tablet if you are allergic to any of its ingredients.
  • Jbmune 500 Tablet must not be taken by women who are pregnant or who may become pregnant, as it may cause miscarriage or birth defects.
  • Inform your doctor before taking Jbmune 500 Tablet if you have a sign of infection such as a fever or sore throat, have any unexpected bruising or bleeding, have a history of digestive system problems such as a stomach ulcer, or have rare hereditary disorders such as Lesch-Nyhan or Kelley-Seegmiller syndrome (conditions caused by a deficiency of the enzyme hypoxanthine-guanine phosphoribosyl-transferase [HGPRT]).
  • Limit your exposure to sunlight as Jbmune 500 Tablet increases the risk of skin cancer.
  • Do not donate blood while taking Jbmune 500 Tablet and for at least 60 days after discontinuing the therapy.
  • Call your doctor right away if you think you or your partner is pregnant or if you miss a menstrual period.
  • Please do not take any vaccinations (live vaccines) as they will not be very effective.

Drug-Drug Interactions

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Mycophenolate MofetilClozapine
Severe
Mycophenolate MofetilMedicinal charcoal
Severe

Drug-Drug Interactions

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Mycophenolate MofetilClozapine
Severe
How does the drug interact with Jbmune 500 Tablet:
Combining Clozapine and Jbmune 500 Tablet can increase the risk of developing serious infections.

How to manage the interaction:
There may be a possibility of interaction between Clozapine and Jbmune 500 Tablet, but it can be taken if prescribed by a doctor. If you're having any of these symptoms like fever, chills, sore throat, or muscle aches, it's important to contact your doctor right away. They may be able to recommend other options for you that won't cause any problems. Don't worry, there are solutions available to help you feel better. Do not discontinue any medications without first consulting your doctor.
Mycophenolate MofetilMedicinal charcoal
Severe
How does the drug interact with Jbmune 500 Tablet:
Taking Jbmune 500 Tablet and Medicinal charcoal may decrease the blood levels of Jbmune 500 Tablet.

How to manage the interaction:
Taking Medicinal charcoal with Jbmune 500 Tablet together can possibly result in an interaction, it can be taken if a doctor has advised it. However, if you notice any unusual symptoms, you should consult a doctor immediately. Do not stop using any medications without consulting a doctor.
Mycophenolate MofetilTeriflunomide
Severe
How does the drug interact with Jbmune 500 Tablet:
Using teriflunomide together with Jbmune 500 Tablet may increase the risk of developing serious infections.

How to manage the interaction:
Although taking Jbmune 500 Tablet and Teriflunomide together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination call a doctor right away. Do not discontinue any medications without consulting a doctor.
Mycophenolate MofetilFingolimod
Severe
How does the drug interact with Jbmune 500 Tablet:
Using fingolimod together with Jbmune 500 Tablet may increase the risk of developing serious infections.

How to manage the interaction:
Although taking Jbmune 500 Tablet and Certolizumab together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination call a doctor right away. Do not discontinue any medications without consulting a doctor.
Mycophenolate MofetilLevonorgestrel
Severe
How does the drug interact with Jbmune 500 Tablet:
Taking Levonorgestrel with Jbmune 500 Tablet can decrease the levels of Levonorgestrel in the body. This increases the risk of severe bleeding and unintended pregnancy.

How to manage the interaction:
Although taking Jbmune 500 Tablet and Levonorgestrel together can cause an interaction, it can be taken if a doctor has suggested it. Contact a doctor if you experience worsening of your symptoms such as hot flashes, vaginal dryness, or abnormal bleeding. Do not discontinue any medication without consulting a doctor.
Mycophenolate MofetilInfliximab
Severe
How does the drug interact with Jbmune 500 Tablet:
Combining Infliximab and Jbmune 500 Tablet can increase the risk of developing serious infections.

How to manage the interaction:
Although taking Jbmune 500 Tablet and Infliximab together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination call a doctor right away. Do not discontinue any medications without consulting a doctor.
Mycophenolate MofetilCholestyramine
Severe
How does the drug interact with Jbmune 500 Tablet:
Co-administration of cholestyramine and Jbmune 500 Tablet may interfere with the action of Jbmune 500 Tablet.

How to manage the interaction:
Although taking cholestyramine and Jbmune 500 Tablet together can result in an interaction, they can be taken together if prescribed by a doctor. Do not stop using any medications without consulting a doctor.
Mycophenolate MofetilColestipol
Severe
How does the drug interact with Jbmune 500 Tablet:
Combining Jbmune 500 Tablet and Colestipol may interfere with the absorption of Jbmune 500 Tablet. This can increase the risk of developing serious infections.

How to manage the interaction:
Although taking Jbmune 500 Tablet and Colestipol together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience Nausea or vomiting, headache, drowsiness, dry mouth, fainting, fast, slow, pounding, or irregular heartbeat or pulse, fever or chills call a doctor right away. Do not discontinue any medications without consulting a doctor.
Mycophenolate MofetilBaricitinib
Severe
How does the drug interact with Jbmune 500 Tablet:
Combining baricitinib and Jbmune 500 Tablet can increase the risk of developing serious infections.

How to manage the interaction:
Although there is an interaction, baricitinib can be taken with Jbmune 500 Tablet if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor.
Mycophenolate MofetilColestyramine
Severe
How does the drug interact with Jbmune 500 Tablet:
Coadministration of Jbmune 500 Tablet and Colestyramine may decrease the blood levels of Jbmune 500 Tablet.

How to manage the interaction:
Although taking Cholestyramine and Jbmune 500 Tablet together can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience Constipation, Diarrhea, Stomach pain, Nausea, or Loss of appetite, consult a doctor. Do not stop using any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a well-balanced and healthy diet as it helps you to recover quickly. A dietitian will help you create a personalised diet plan tailored to your specific health condition.
  • Avoid eating raw or undercooked food.
  • Protect yourself from exposure to sunlight and soil. Wear a long-sleeved shirt, a hat, long pants, and closed-toe shoes when going outdoors. Also, wear sunscreen with high SPF.
  • Stay away from people who are sick.
  • Limit alcohol consumption and quit smoking.
  • Discuss your travel plans with your doctor at least two months in advance, especially if you plan to travel, especially to developing countries.

Habit Forming

No

Therapeutic Class

IMMUNOSUPPRESSANTS
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Alcohol

Caution

Consuming alcohol while taking Jbmune 500 Tablet may worsen the condition by increasing the risk of side effects.

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Pregnancy

Unsafe

Jbmune 500 Tablet is a pregnancy category D drug. It causes birth defects in the fetus. So, it is not recommended for use in pregnant women.

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Breast Feeding

Unsafe

Jbmune 500 Tablet is not recommended for breastfeeding mothers, as it may be excreted in the breast milk. However, your doctor may prescribe Jbmune 500 Tablet if the benefits outweigh the risks.

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Driving

Caution

Jbmune 500 Tablet may moderately affect your ability to drive. If you experience drowsiness, confusion, or numbness after taking Jbmune 500 Tablet , consult your doctor for advice, and avoid driving or operating machinery until you feel well again.

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Liver

Caution

Jbmune 500 Tablet should be used with caution in patients with liver diseases. Dose adjustments may be necessary.

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Kidney

Caution

Jbmune 500 Tablet should be used with caution in patients with kidney diseases. Dose adjustments may be necessary.

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Children

Caution

Jbmune 500 Tablet should be used with caution in children below 12 years of age. Dose adjustments may be necessary.

Have a query?

FAQs

Jbmune 500 Tablet is used to prevent the body from rejecting a transplanted organ such as a kidney, heart‚ or liver.

Jbmune 500 Tablet belongs to the group of medications called immunosuppressants. It works by weakening the immune system by inhibiting the production of cells or antibodies that attack foreign cells. This effect helps in stopping the immune system from targeting and rejecting the transplanted organ.

Jbmune 500 Tablet can suppress the immune system and can increase the risk of skin cancer. Therefore, it is advisable to avoid prolonged exposure to sunlight. Also, wear protective clothing that covers your head, neck, arms, and legs, and use a sunscreen lotion with a high SPF (sun protection factor).

Jbmune 500 Tablet can suppress the immune system. So, you should not donate blood while using Jbmune 500 Tablet and at least 60 days after stopping treatment, as it makes you more prone to infections. Besides, men should not donate sperm while using Jbmune 500 Tablet for at least 90 days after stopping the treatment.

It is not advised to get pregnant while using Jbmune 500 Tablet , as it may cause birth defects/congenital disabilities in the unborn baby. So, it would help if you took an effective and reliable contraceptive while using Jbmune 500 Tablet , even when men are taking Jbmune 500 Tablet .

Jbmune 500 Tablet is given to stop rejection of the transplanted organ. If you abruptly stop taking this drug, it might result in rejection of the transplanted organ. So, check with your doctor if you want to stop using Jbmune 500 Tablet .

Jbmune 500 Tablet may increase the risk of skin cancer as it reduces the body’s defences. Limit the amount of sunlight and UV light, wear protective clothing and use sunscreen with high SPF.

Your doctor has prescribed Jbmune 500 Tablet to suppress your immune system and prevent rejection of the transplanted kidney.

Jbmune 500 Tablet is not a steroid or chemotherapy medicine. It is an immunosuppressant used to prevent organ rejection after a transplant.

The doctor may recommend regular blood tests to check for signs of infection and blood count. Women of childbearing potential must provide a negative pregnancy test before the start of treatment.

As Jbmune 500 Tablet reduces the body’s defences, you may be at a higher risk of developing infections. Therefore, your doctor has advised you to avoid contact with a person who has chickenpox or shingles.

Jbmune 500 Tablet causes a high frequency of miscarriage and birth defects. Therefore, before the start of treatment, women of childbearing potential must provide a negative pregnancy test. Also, women who can become pregnant should use effective contraception during treatment and for 6 months after stopping Jbmune 500 Tablet . Two forms of contraception are preferable as this will reduce the risk of unintended pregnancy. Contact the doctor about the effective methods of contraception.

As a precaution, the male or his female partner must use reliable contraception during treatment and for 90 days after stopping Jbmune 500 Tablet .

The common side effects of Jbmune 500 Tablet are diarrhoea, vomiting, decreased white blood cell and red blood cell count, and infections. Most of these side effects do not require medical attention and resolve gradually over time. However, consult your doctor right away if any of these side effects persist or worsen.

Country of origin

India

Manufacturer/Marketer address

Cnergy It Park, 3Rd Floor Appa Saheb Marathe Marg, Prabhadevi, Mumbai 400025.
Other Info - JBM0001

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