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  3. Ixapana 20Mg Capsule 6'S

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Ixapana 20Mg Capsule 6'S, Pack of 6 CapsuleS
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Ixapana 20Mg Capsule is an anti-cancer medicine used to treat multiple myeloma. It contains Panobinostat, which works by blocking the action of histone deacetylase in myeloma cells. Thereby, it can prevent myeloma cells from growing and multiplying. It should not be taken during pregnancy as it might cause fetal harm. Inform your doctor immediately if you are conceiving while on therapy. Advise women not to breastfeed while taking Ixapana 20Mg Capsule.

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Composition :

PANOBINOSTAT-20MG

Manufacturer/Marketer :

Emcure Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Ixapana 20Mg Capsule

Ixapana 20Mg Capsule belongs to the group of anti-cancer medicines used to treat multiple myeloma. Multiple myeloma, also known as myeloma, is a type of bone marrow cancer that affects several areas of the body, such as the spine, skull, pelvis, and ribs.

Ixapana 20Mg Capsule contains Panobinostat. It works by blocking the action of histone deacetylase in myeloma cells. Thereby, it can prevent myeloma cells from growing and multiplying.

Depending on your medical condition, you are advised to take Ixapana 20Mg Capsule for as long as your doctor prescribes it. Sometimes, you may experience common side effects, such as diarrhoea, fatigue, nausea, peripheral oedema, decreased appetite, pyrexia, vomiting and hematologic laboratory abnormalities. Do not be reluctant to talk with your doctor if you persistently experience any of these side effects.

Do not take Ixapana 20Mg Capsule if you are allergic to any of its components or if you are pregnant. Do not try to become pregnant as Ixapana 20Mg Capsule may cause Embryo-Fetal Toxicity. Advise women not to breastfeed while taking Ixapana 20Mg Capsule. Inform your doctor if you are suffering from Hepatic dysfunction, as this increases panobinostat exposure. Your doctor reduces the dose in patients with mild to moderate hepatic (liver) impairment. It is recommended not to be used in people with severe hepatic (liver) impairment. If you feel dizzy or lightheaded when taking panobinostat, you should not operate machinery or drive a car.

Uses of Ixapana 20Mg Capsule

Ixapana 20Mg Capsule is used in the treatment of Multiple myeloma. The detailed uses of Ixapana 20Mg Capsule are as follows:

  • Multiple Myeloma: Ixapana 20Mg Capsule is used in the treatment of Multiple Myeloma.

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Directions for Use

  • Ixapana 20Mg Capsule can be taken with or without food as prescribed by your doctor.
  • It is usually taken on days 1, 3, 5, 8, 10 and 12 of a 21-day (3-week) cycle for up to 16 cycles or as advised by your doctor.
  • Swallow the medicine as a whole with a glass of water.
  • Do not break, crush or chew Ixapana 20Mg Capsule.

Medicinal Benefits

Ixapana 20Mg Capsule contains Panobinostat, which belongs to the anti-cancer medicines used to treat multiple myeloma. It works by blocking the action of histone deacetylase in myeloma cells. Thereby, it can prevent myeloma cells from growing and multiplying.

How Ixapana 20Mg Capsule Works

Ixapana 20Mg Capsule contains Panobinostat. It works by blocking the action of histone deacetylase in myeloma cells. Thereby, it can prevent myeloma cells from growing and multiplying.

Storage

• Store in a cool and dry place away from sunlight.• Keep Ixapana 20Mg Capsule out of reach and sight of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Ixapana 20Mg Capsule
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Eat well-cooked food to minimize infection risk.
  • Practice good hand hygiene to prevent infections.
  • Avoid crowds and people with illnesses to reduce exposure.
  • Wear a mask when necessary to lower infection risk.
  • Rest adequately to support your body's healing process.
  • Stay hydrated by drinking plenty of water.
  • Regularly monitor blood cell counts for changes.
  • Seek immediate medical help if symptoms like fever, chills, or fatigue occur.
  • Consult your doctor right away if concerning symptoms arise.
  • Follow your doctor's guidance on managing myelosuppression and infection prevention.
  • Avoid alcohol as it may be harmful and worsen certain condition.
  • Take nutritional supplements only as advised by your doctor.
  • Limit sodium intake.
  • Consult your doctor for medications to treat your condition effectively.
  • Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
  • Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
  • Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
  • Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
  • If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
  • In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
  • Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
  • If you experience severe bleeding or bruising, seek emergency medical attention immediately.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.

What if I have taken an overdose of Ixapana 20Mg Capsule

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Ixapana 20Mg Capsule may include severe nausea, severe vomiting, severe diarrhoea, and easy bruising/bleeding. Seek immediate medical attention if you observe any symptoms or think you have taken too much. Do this even if there are no signs of discomfort or poisoning.

Drug Warnings

Do not take Ixapana 20Mg Capsule if you are allergic to any of its contents. Inform your doctor about your health condition and medications to rule out any side effects/interactions. Always take this medicine exactly as your doctor or healthcare professional has told you. To treat your condition effectually, continue taking Ixapana 20Mg Capsule for as long as your doctor has prescribed. Do not stop Ixapana 20Mg Capsule midway. Talk to your doctor before taking Ixapana 20Mg Capsule if you have severe allergic reactions to Ixapana 20Mg Capsule or other medicines or suffer from any medical illness. Avoid taking Ixapana 20Mg Capsule if you are pregnant or breastfeeding because this Ixapana 20Mg Capsule can cause harmful effects on the unborn baby. Both women and men using this Ixapana 20Mg Capsule should use birth control to avoid pregnancy. Inform your doctor if you have a history of low blood pressure; your doctor will closely monitor and manage it. If you are taking medication to help lower your blood pressure, you may need to reduce or discontinue it while taking panobinostat.

Drug-Drug Interactions

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PanobinostatRifabutin
Critical
PanobinostatEtodolac
Severe

Drug-Drug Interactions

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PanobinostatRifabutin
Critical
How does the drug interact with Ixapana 20Mg Capsule:
Taking Rifabutin and Ixapana 20Mg Capsule may significantly reduce the blood levels of Ixapana 20Mg Capsule.

How to manage the interaction:
Taking Rifabutin with Ixapana 20Mg Capsule is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately, iff you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
PanobinostatEtodolac
Severe
How does the drug interact with Ixapana 20Mg Capsule:
Use of Ixapana 20Mg Capsule with etodolac may increase the risk of bleeding and severe hemorrhage.

How to manage the interaction:
Taking Etodolac with Ixapana 20Mg Capsule together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, a severe headache, and/or weakness, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
PanobinostatLenvatinib
Severe
How does the drug interact with Ixapana 20Mg Capsule:
Coadministration of Ixapana 20Mg Capsule with lenvatinib can increase the risk of of an irregular heart rhythm.

How to manage the interaction:
Although there is an interaction between Lenvatinib and Ixapana 20Mg Capsule, they can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
PanobinostatPazopanib
Severe
How does the drug interact with Ixapana 20Mg Capsule:
Using Ixapana 20Mg Capsule together with pazopanib can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there is a possible interaction between Pazopanib and Ixapana 20Mg Capsule, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
PanobinostatParoxetine
Severe
How does the drug interact with Ixapana 20Mg Capsule:
Taking Ixapana 20Mg Capsule together with paroxetine may increase the risk of bleeding.

How to manage the interaction:
Although taking Paroxetine and Ixapana 20Mg Capsule together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, consult your doctor immediately if you experience any unusual bleeding or bruising, or have other signs and symptoms of bleeding such as dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop using any medications without a doctor's advice.
PanobinostatAmisulpride
Severe
How does the drug interact with Ixapana 20Mg Capsule:
Taking amisulpride with Ixapana 20Mg Capsule increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Although taking Amisulpride along with Ixapana 20Mg Capsule can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
PanobinostatNilotinib
Severe
How does the drug interact with Ixapana 20Mg Capsule:
Combining Ixapana 20Mg Capsule and nilotinib can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Ixapana 20Mg Capsule and nilotinib together can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
PanobinostatVenlafaxine
Severe
How does the drug interact with Ixapana 20Mg Capsule:
Although it is a very rare adverse effect, taking venlafaxine with Ixapana 20Mg Capsule increases the risk of an abnormal heart rhythm. If you're dealing with heart illnesses or electrolyte imbalances (for example, magnesium or potassium loss likely due to serious or prolonged diarrhoea or vomiting), you may be at greater risk.

How to manage the interaction:
There may be a possibility of interaction between Venlafaxine and Ixapana 20Mg Capsule, but it can be taken if prescribed by a doctor However, consult your doctor immediately if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat. Do not discontinue any medications without first consulting your doctor.
PanobinostatOndansetron
Severe
How does the drug interact with Ixapana 20Mg Capsule:
Taking Ondansetron with Ixapana 20Mg Capsule increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Co-administration of Ondansetron along with Ixapana 20Mg Capsule can result in an interaction, it can be taken if a doctor has advised it. However, consult a doctor if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat. Do not discontinue any medications without a doctor's advice.
PanobinostatAzithromycin
Severe
How does the drug interact with Ixapana 20Mg Capsule:
Taking Azithromycin with Ixapana 20Mg Capsule increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Although administration of azithromycin alongside Ixapana 20Mg Capsule can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Performing yoga may also help in improving both physical and mental health.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugars.

Habit Forming

No

Therapeutic Class

CHEMOTHERAPY

All Substitutes & Brand Comparisons

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Alcohol

Caution

Avoid alcohol consumption while on treatment with Ixapana 20Mg Capsule.

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Pregnancy

Unsafe

Ixapana 20Mg Capsule should not be taken during pregnancy as it might cause fetal harm. Inform your doctor immediately if you are conceiving while on therapy.

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Breast Feeding

Unsafe

You should not breastfeed when taking Ixapana 20Mg Capsule as it is unknown if the panobinostat can pass to your baby in the milk.

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Driving

Caution

Ixapana 20Mg Capsule can cause a drop in blood pressure, which can make you feel dizzy, lightheaded or like you are about to faint. If you feel dizzy or lightheaded when taking Ixapana 20Mg Capsule, you should not operate machinery or drive a car.

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Liver

Caution

Caution should be exercised. Monitor hepatic enzymes and adjust the dosage if abnormal liver function tests are observed during panobinostat therapy.

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Kidney

Caution

Limited information is available. Please inform your doctor before prescribing Ixapana 20Mg Capsule if you have kidney impairment. Your doctor will weigh the benefits and potential risks before prescribing Ixapana 20Mg Capsule.

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Children

Consult your doctor

The safety and efficacy of Ixapana 20Mg Capsule in children has not been established.

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Heart

Ixapana 20Mg Capsule should be used with caution and under medical supervision in patients with heart problems. Therefore, please consult your doctor before using Ixapana 20Mg Capsule.

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Geriatrics

Consult your doctor

Please consult a doctor before administering Ixapana 20Mg Capsule to geriatric patients. Your doctor will prescribe Ixapana 20Mg Capsule if the benefits outweigh the risks.

FAQs

Ixapana 20Mg Capsule is used to treat Multiple myeloma.

Ixapana 20Mg Capsule contains Panobinostat. It works by blocking the action of histone deacetylase in myeloma cells. Thereby, it can prevent myeloma cells from growing and multiplying.

Do not stop taking Ixapana 20Mg Capsule on your own. Depending on your medical condition, you are advised to take Ixapana 20Mg Capsule for as long as your doctor prescribes it. Do not hesitate to speak with your doctor if you experience difficulty taking Ixapana 20Mg Capsule.

No, it is unsafe to father a child while taking Ixapana 20Mg Capsule. It is recommended for sexually active men to use condoms while on treatment and for at least six months after their last dose of Ixapana 20Mg Capsule.

The amount of red blood cells, white blood cells, and platelets in your blood may decrease as a result of Ixapana 20Mg Capsule. This can lead to anaemia (shortness of breath, exhaustion, and weakness) and fatigue, and make you more prone to infection and increase your risk of bleeding. You will be given supportive medication to alleviate these adverse effects and increase your blood cell count if necessary.

Panobinostat can induce swelling in the hands, ankles, and feet (peripheral oedema). Fluid may also accumulate around the abdomen, making you feel bloated. Your doctor will discuss a treatment strategy for your fluid retention with you. Diuretics (water tablets) are typically used to assist your body in removing excess fluid.

Ixapana 20Mg Capsule should be used for the duration prescribed by the doctor. The exact duration depends on your situation, response to treatment, and overall health. Consult the doctor if you have any concerns.

No, it is not safe to use Ixapana 20Mg Capsule during pregnancy as it can harm the fetus. Use effective birth control during treatment and for at least one month after the final dose to prevent pregnancy. If you're pregnant or planning to become pregnant, consult your doctor.

Ixapana 20Mg Capsule can be taken with or without food. Swallow the medicine as a whole with water; do not crush or chew it.

Before taking Ixapana 20Mg Capsule, inform your doctor if you have any allergies or if you are taking any other medicines. Ixapana 20Mg Capsule can harm the foetus, so use birth control during treatment for 3 month after the last dose. Men should use condoms during treatment and for 90 days after the treatment. Inform your doctor before undergoing any surgery or dental procedure that you are taking Ixapana 20Mg Capsule.

Ixapana 20Mg Capsule is generally considered safe when used as directed by a healthcare professional. However, like all medications, it may have side effects and potential risks. Common side effects include fatigue, nausea, diarrhoea, and changes in blood cell counts. It is essential to follow your doctor's instructions and monitoring schedule to minimize risks.

No, it does not contain steroids. Ixapana 20Mg Capsule is a histone deacetylase inhibitor, which is used to treat certain types of cancer, such as multiple myeloma.

While taking Ixapana 20Mg Capsule, regular blood tests are crucial to monitor blood cell counts, liver function tests, and electrolyte levels. Your doctor may also recommend electrocardiograms to check heart rhythm and pregnancy tests for women of childbearing age.

The effect of Ixapana 20Mg Capsule is not permanent. Ixapana 20Mg Capsule is a targeted therapy that inhibits the growth of cancer cells, but it does not eliminate the cancer. Consult your doctor if you have concerns regarding it.

Ixapana 20Mg Capsule should not be taken during pregnancy as it can harm the developing foetus. Women of child-bearing potential should use effective contraception during treatment with Ixapana 20Mg Capsule and for 3 months after the last dose.

No, it doesn’t cause cancer. In fact, Ixapana 20Mg Capsule is an anti-cancer medication, specifically designed to treat certain types of cancer, such as multiple myeloma.

The common side effects of Ixapana 20Mg Capsule may include diarrhoea, fatigue, nausea, swelling in your extremities, decreased appetite, fever, vomiting, and changes in blood test results. Don't hesitate to talk to your doctor if you're persistently experiencing any of these side effects.

Ixapana 20Mg Capsule may impair male and female fertility. Talk to the doctor if you have any concerns regarding this.

Ixapana 20Mg Capsule may cause liver damage in some people. Consult the doctor if you notice signs of liver problems such as stomach pain (upper right side), loss of appetite, jaundice (yellowing of skin and eyes), or dark urine.

Country of origin

India

Manufacturer/Marketer address

255/2, Hinjawadi, Pune - 411057, India
Other Info - IXA0003

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Sep 18, 2025 | 11:51 AM IST

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Reference

  1. https://www.myeloma.org.uk/wp-content/uploads/2023/04/Myeloma-UK-Panobinostat-Treatment-Guide.pdf
  2. https://chemocare.com/druginfo/panobinostat
  3. https://www.clinicaltrialsarena.com/projects/farydak-panobinostat-treatment-multiple-myeloma/
  4. https://www.novartis.com/us-en/sites/novartis_us/files/farydak.pdf

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