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  3. Itolizac 100 mg Injection 1's

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Itolizac 100 mg Injection 1's, Pack of 1 INJECTION
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Itolizac 100 mg Injection is used to treat psoriasis. It contains Itolizumab which works by reducing the synthesis of substances that cause inflammation. In some cases, this medicine may cause side effects such as pain and swelling at the injection site, fever, itching, dizziness, and diarrhoea. Let the doctor know if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Composition :

ITOLIZUMAB-100MG

Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Itolizac 100 mg Injection

Itolizac 100 mg Injection belongs to the class of 'immunomodulators', primarily used to treat psoriasis. Psoriasis is a skin disorder in which skin cells multiply and form bumpy (uneven) red patches covered with white scales. Itolizac 100 mg Injection may also be used to treat autoimmune conditions like rheumatoid arthritis and multiple sclerosis. Itolizac 100 mg Injection is currently being used and trialled to treat cytokine storm (excessive immune response) in COVID-19 (Corona Virus Disease-19) patients. 

Itolizac 100 mg Injection consists of 'Itolizumab' that is a humanized recombinant IgG1 (Immunoglobulin G1) monoclonal antibody (that serve as a substitute antibody). It works by reducing the synthesis of cytokine, a substance released by the body that initiates an inflammatory response. Lately, Itolizac 100 mg Injection is also being used in COVID-19 infection to reduce the severity of inflammation and damage in the lungs. It is thought to decrease the cytokine storm, an excessive immune response in the lungs of a COVID-19 infected person.

Your doctor will decide the dose and duration based on the medical condition. Common side effects of Itolizac 100 mg Injection include pain and swelling at the injection site, upper respiratory tract infection, fever, itching, dizziness, and diarrhoea. These side effects are not familiar to everyone and vary individually. However, if the side effects are persistent, please reach out to your doctor.

Before starting Itolizac 100 mg Injection, inform your doctor if you have any liver, heart or kidney diseases, bone marrow suppression, weak immune system (HIV), tuberculosis, hepatitis B, and active infections. Let your doctor know if you are pregnant or breastfeeding before starting Itolizac 100 mg Injection. Itolizac 100 mg Injection may cause dizziness, so drive only if you are alert and focused. Itolizac 100 mg Injection should not be given to children and adolescents under 18 years of age as safety has not been established. Avoid consuming alcohol along with Itolizac 100 mg Injection as it could lead to increased dizziness. 

Uses of Itolizac 100 mg Injection

Treatment of Psoriasis, Rheumatoid arthritis, and COVID-19.

Have a query?

Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.• Itolizac 100 mg Injection will be administered by the doctor or healthcare professional.• Do not self-administer.

Medicinal Benefits

Itolizac 100 mg Injection treats inflammation in patients with psoriasis and rheumatoid arthritis. It contains 'Itolizumab,' which is a humanized recombinant IgG1 (Immunoglobulin G1) monoclonal antibody. It works by reducing the synthesis of cytokine, a substance released by the body that initiates an inflammatory response. Lately, Itolizac 100 mg Injection is also being used in COVID-19 infection to reduce breathing complications, the severity of inflammation, and damage in the lungs. It is being used to decrease the cytokine storm, an excessive immune response that occurs in the lungs of a COVID-19-infected person. 

How Itolizac 100 mg Injection Works

Itolizac 100 mg Injection consists of 'Itolizumab' that is a humanized recombinant IgG1 (Immunoglobulin G1) monoclonal antibody (that serve as a substitute antibody). It works by reducing the synthesis of cytokine, a substance released by the body that initiates an inflammatory response. Lately, Itolizac 100 mg Injection is also being used in COVID-19 infection to reduce the severity of inflammation and damage in the lungs. It is thought to decrease the cytokine storm, an excessive immune response in the lungs of a COVID-19 infected person.

Storage

• Store in a cool and dry place away from sunlight.• Keep out of sight and reach of children.• Cold chain - To be stored in cold places at 2ºC to 8ºC.
Side effects of Itolizac 100 mg Injection
  • Rest well; get enough sleep.
  • Wear comfortable layers of clothes and get to a warm place.
  • Drink warm fluids like coffee, tea or hot chocolate.
  • Warm up using a blanket or heating pad.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
Here are the steps to manage Joint Pain caused by medication usage:
  • Please inform your doctor about joint pain symptoms, as they may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Your doctor may prescribe common pain relievers if necessary to treat joint discomfort.
  • Maintaining a healthy lifestyle is key to relieving joint discomfort. Regular exercise, such as low-impact sports like walking, cycling, or swimming, should be combined with a well-balanced diet. Aim for 7-8 hours of sleep per night to assist your body in repairing and rebuilding tissue.
  • Applying heat or cold packs to the affected joint can help reduce pain and inflammation.
  • Please track when joint pain occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • If your joint pain is severe or prolonged, consult a doctor to rule out any underlying disorders that may require treatment.
  • Include omega-3 rich foods like fatty fish, ground flax, flaxseed oil, and walnuts.
  • Consume calcium-rich dairy products for bone health.
  • Eat green and leafy vegetables for essential nutrients.
  • Include lean protein sources like eggs and whole grains.
  • Use herbs and spices for added flavor and nutrition.
  • Choose fortified foods for extra nutritional benefits.
  • Get plenty of sleep for overall health and well-being.

What if I have taken an overdose of Itolizac 100 mg Injection

It is unlikely to overdose on parenteral medication as it is administered by a healthcare professional. However, seek medical attention if you experience any unusual symptoms. If you suspect you have taken an overdose, seek immediate medical attention. In case of overdose, it is recommended that the patient be monitored for any signs and symptoms of adverse reactions and that appropriate symptomatic treatment be initiated.

Drug Warnings

Inform your doctor if you have any liver, heart or kidney diseases, bone marrow suppression, low blood cell count, weak immune system (HIV), neutropenia (low levels of neutrophils), lymphopenia (low levels of lymphocytes), tuberculosis, hepatitis B, C, and active infections before starting Itolizac 100 mg Injection. Avoid close contact with people who have infections like chickenpox, measles, tuberculosis, and flu that can be easily spread. Thoroughly wash your hands to prevent the spread of infection. Do not take live vaccines while being treated with Itolizac 100 mg Injection to prevent any serious consequences. Itolizac 100 mg Injection may cause dizziness, so drive only if you are alert and focused. Avoid consuming alcohol along with Itolizac 100 mg Injection as it could lead to increased dizziness. Itolizac 100 mg Injection is not recommended in children and adolescents younger than 18 years of age as safety and efficacy is not established. Store Itolizac 100 mg Injection at temperatures of 2°C to 8°C. Do not freeze the vial.

Drug-Drug Interactions

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No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

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Diet & Lifestyle Advise

  • Maintain proper weight by following a healthy and well-balanced diet.
  • Avoid smoking and alcohol consumption.
  • Try to avoid stress by practising meditation or yoga.
  • Try including selenium-rich food sources like Brazil nuts, yellowfin tuna, rice, beans, whole-wheat bread, dairy products, ham, chicken, turkey, beef, eggs, pork, baked beans, mushrooms, oatmeal, and spinach.
  • Include zinc-rich sources like meat, shellfish, legumes, hemp seeds, nuts, eggs, dairy products, whole grains, potatoes, kale, and dark chocolate in your diet.
  • Cut down on sugar, salt and processed foods.
  • Drink plenty of water.

Habit Forming

No

Therapeutic Class

IMMUNOMODULATORS
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Alcohol

Caution

You are recommended to avoid alcohol consumption while taking Itolizac 100 mg Injection. Alcohol intake, along with Itolizac 100 mg Injection, may cause increased dizziness.

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Pregnancy

Unsafe

Itolizac 100 mg Injection is not recommended during pregnancy since it may have harmful effects on the developing baby. Your doctor will prescribe Itolizac 100 mg Injection only if the benefit outweighs the risk.

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Breast Feeding

Caution

It is not known if Itolizac 100 mg Injection passes into the breastmilk when used by breastfeeding mother. Your doctor will prescribe Itolizac 100 mg Injection only if the benefit outweighs the risk.

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Driving

Unsafe

Itolizac 100 mg Injection may make you feel dizzy. Do not drive or operate machinery if you experience dizziness.

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Liver

Caution

Please consult your doctor since Itolizac 100 mg Injection should be used with caution in patients with liver impairment/liver disease. Dose adjustment may be needed in patients with liver impairment. However, Itolizac 100 mg Injection is not recommended in patients with active liver diseases.

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Kidney

Caution

Please consult your doctor since Itolizac 100 mg Injection should be used with caution in patients with kidney impairment/kidney disease. Dose adjustment may be required.

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Children

Unsafe

Itolizac 100 mg Injection is not recommended in children and adolescents younger than 18 years of age.

FAQs

Itolizac 100 mg Injection contains Itolizumab, an immunomodulator. It reduces the synthesis of pro-inflammatory markers called cytokines. Thus, it helps in decreasing inflammation in various diseases like psoriasis, rheumatoid arthritis, and multiple sclerosis.

When a person is infected with the coronavirus, his/her immune system responds in such a way that it sends useful immune chemicals to the affected areas of the lungs to fight the infection. However, in some people, this release of immune chemicals is overactive, resulting in a cytokine storm, an excessive immune response in the lungs. This can further lead to severe breathing complications in an infected person. Itolizac 100 mg Injection reduces this cytokine storm and further prevents the inflammation and damage in the lungs of a COVID-19 infected person.

Itolizac 100 mg Injection is currently being used to decrease the negative outcome of the cytokine storm in critically, severely and moderately ill COVID-19 patients.

Itolizac 100 mg Injection is not recommended for every person infected with the coronavirus. Itolizac 100 mg Injection is only prescribed by doctors in patients with severe and critical COVID infection.

Itolizac 100 mg Injection is to be carefully administered with caution in patients under doctor's supervision only. The safety of Itolizac 100 mg Injection is not yet evaluated in conditions like neutropenia (low levels of neutrophils), lymphopenia (low levels of lymphocytes), AIDS, tuberculosis, hepatitis B and C.

Even if there is no improvement after administering Itolizac 100 mg Injection, your doctor may suggest an alternate course. Please note that Itolizac 100 mg Injection does not reverse the damage caused due to coronavirus infection, but it will further prevent the inflammation of the lungs. It is also advised to medically examine for other lung and heart related dysfunctions even the patient suffers breathlessness after Itolizac 100 mg Injection administration.

It is not recommended to get live attenuated vaccines while being treated with Itolizac 100 mg Injection. This may lead to serious conditions. Please consult a doctor before you start Itolizac 100 mg Injection if you are undergoing any vaccinations.

Country of origin

India

Manufacturer/Marketer address

Sun Pharmaceutical Industries Ltd., Sun House, Cts No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Other Info - ITO0055

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:28 PM IST

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Reference

  1. https://www.dovepress.com/spotlight-on-itolizumab-in-the-treatment-of-psoriasis-current-perspect-peer-reviewed-fulltext-article-PTT#:~:text=Itolizumab%20was%20efficacious%20with%20a,and%20efficacy%20of%20the%20drug.
  2. https://bioconweb.files.wordpress.com/2020/08/itolizumab-an-anti-cd6-monoclonal-antibody-as-a-potential-treatment-for-covid-19-complications.pdf
  3. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5527725/

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