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  3. Itapro SR 400 Tablet 4's

Itapro SR 400 Tablet 4's, Pack of 4 TABLETS
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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Itapro SR 400 Tablet is an antifungal medicine used to treat fungal infections of the mouth, throat, toenails, fingernails or lungs. It contains Itraconazole, which works by killing fungi. Some people may experience side effects such as nausea, headache, diarrhoea, tiredness, cough, cold, throat pain, back pain and stomach pain. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

ITRACONAZOLE-400MG

Manufacturer/Marketer :

Ajanta Pharma Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Itapro SR 400 Tablet

Itapro SR 400 Tablet is an antifungal medicine used to treat fungal infections of the mouth, throat, toenails, fingernails or lungs. Fungal infection is a disease in which a fungus attacks the tissue and causes infection. Fungal infections may be contagious (spread from one person to another).

Itapro SR 400 Tablet contains Itraconazole, an antifungal that works by inhibiting the production of ergosterol (a main component of cell membranes of fungi). Thereby, weakens and damages the fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents.Thus, it causes the main components of fungal cells to leak out, killing fungi and clearing the fungal infection.

Take Itapro SR 400 Tablet as prescribed. Your doctor will advise you on how often you take Itapro SR 400 Tablet based on your medical condition. Some people may experience nausea, headache, diarrhoea, tiredness, cough, cold, throat pain, back pain and stomach pain. Most of these side effects of Itapro SR 400 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Itapro SR 400 Tablet or any other medicines, please tell your doctor. Itapro SR 400 Tablet is a pregnancy category C drug and may cause harm to the unborn baby. However, if you are pregnant, planning for pregnancy or a nursing mother, it is advised to consult a doctor before using Itapro SR 400 Tablet. Do not take Itapro SR 400 Tablet if you have or have heart failure, as it may cause severe life-threatening adverse effects. If you have kidney, liver, heart or lung problems, inform your doctor before taking Itapro SR 400 Tablet. Avoid taking fentanyl (a strong opioid narcotic medicine) with Itapro SR 400 Tablet as it may cause severe breathing problems and can even lead to death. If you experience numbness or tingling in your hands or feet, stop taking Itapro SR 400 Tablet and consult your doctor immediately as they might be symptoms of nerve damage.

Uses of Itapro SR 400 Tablet

Itapro SR 400 Tablet is used in the treatment of fungal infections. The detailed uses of Itapro SR 400 Tablet are as follows:

  • Yeast Infection Treatment: Itapro SR 400 Tablet is commonly used to combat vaginal yeast infections caused by the Candida fungus.
  • Fungal Infection Management: Itapro SR 400 Tablet effectively treats various systemic fungal infections, especially in individuals with weakened immune systems.
  • Preventive Care: Doctors may prescribe Itapro SR 400 Tablet to prevent fungal infections in patients undergoing chemotherapy or those prone to such infections due to immune deficiencies.
  • Oral Thrush Treatment: Itapro SR 400 Tablet is also useful in managing oral candida (thrush), a fungal overgrowth in the mouth caused by Candida.

Directions for Use

• Take Itapro SR 400 Tablet with food to prevent stomach upset or as advised by your doctor. • Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use. • Swallow Itapro SR 400 Tablet as a whole with a glass of water. • Do not crush, chew or break it.

Medicinal Benefits

Itapro SR 400 Tablet is an antifungal used to treat fungal infections of the mouth, throat, toenails, fingernails or lungs. The fungal cell membranes are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Itapro SR 400 Tablet inhibits the production of ergosterol (a main component of the cell membranes of fungi). This weakens and damages the fungal cell membranes, causing the main components of fungal cells to leak out. Thus, it kills fungi and clears the fungal infection.

How Itapro SR 400 Tablet Works

Itapro SR 400 Tablet contains Itraconazole, an antifungal that works by inhibiting the production of ergosterol (a main component of the cell membranes of fungi). Thereby, weakens and damages the fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents.Thus, it causes the main components of fungal cells to leak out, killing fungi and clearing the fungal infection.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Itapro SR 400 Tablet
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Talk to your doctor about oral potassium supplements.
  • Eat potassium rich foods such as bananas, avocados, oranges, dark leafy greens, beans and peas, fish, spinach, milk and tomatoes.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • To help reduce symptoms, eat foods high in vitamin C, such as oranges, bell peppers and strawberries.
  • Lightly blow your nose to remove mucus; steer clear of blowing hard.
  • Infections can be prevented from spreading by washing hands frequently and staying away from other people.
  • If you have allergies, do your best to avoid triggering allergens that could contribute to a runny nose.
  • Don't smoke, as irritating the nasal passages can make a runny nose worse.
  • High levels of liver enzymes need immediate medical attention.
  • Watch your diet and consume low-fat foods, like green leafy vegetables, fish, whole grains, nuts, etc.
  • Regularly do strengthening exercises to control your cholesterol levels.
  • Avoid drinking alcohol as it can affect your liver.
  • Focus on losing weight as it can help control cholesterol and maintain liver enzymes.
  • Practice yoga and meditation to improve liver functioning and overall health.
Here's a comprehensive approach to managing medication-triggered high blood pressure (hypertension):
  • Inform your doctor if you experience high blood pressure symptoms after starting a new medication or changing your medication regimen.
  • To reduce high blood pressure symptoms, your doctor may change your medication regimen or dose.
  • Monitor your blood pressure regularly to track changes and potential side effects.
  • Make lifestyle changes, such as following a healthy diet, exercising regularly, and reducing sodium intake.
  • Consider incorporating stress-reducing activities, like meditation or deep breathing exercises, into your daily routine.
  • Create a personalized plan with your doctor to manage high blood pressure, which may include additional medications, therapies, or lifestyle modifications.
  • Follow up with your doctor on a frequent basis to assess progress, change treatment plans, and address any concerns or issues.
  • Increased creatinine levels must be corrected immediately with the help of a doctor.
  • Reduce strenuous activities that can lead to muscle breakdown and production of creatinine.
  • Sleep for 7-8 hours per night to assist your body in repairing and rebuilding tissue.
  • Manage your blood pressure by implementing changes in lifestyle like losing weight, reducing stress and exercising regularly.
  • Avoid smoking and drinking alcohol.

What if I have taken an overdose of Itapro SR 400 Tablet

Do not take more than the prescribed dose of Itapro SR 400 Tablet as it may cause an overdose. If you suspect you have taken an overdose, please consult a doctor immediately.

Drug Warnings

If you are known to be allergic to Itapro SR 400 Tablet or any other medicines, please tell your doctor. Itapro SR 400 Tablet is a pregnancy category C drug and may cause harm to the unborn baby. However, if you are pregnant, planning for pregnancy, or are a nursing mother, it is advised to consult a doctor before using Itapro SR 400 Tablet. Avoid taking fentanyl (a strong opioid pain killer narcotic medicine) with Itapro SR 400 Tablet, as it may cause severe breathing problems and can even lead to death. Do not take Itapro SR 400 Tablet if you have had heart failure, as it may cause severe, life-threatening adverse effects. If you experience a yellow colour change of your eyes or skin, dark coloured urine, stomach pain, pale stools, loss of appetite, unusual tiredness, vomiting or nausea, stop taking Itapro SR 400 Tablet and consult a doctor immediately, as they might be symptoms of liver failure. If you have kidney, liver, heart, or lung problems, inform your doctor before taking Itapro SR 400 Tablet.

Drug-Drug Interactions

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ItraconazoleSimvastatin
Critical
ItraconazoleNisoldipine
Critical

Drug-Drug Interactions

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ItraconazoleSimvastatin
Critical
How does the drug interact with Itapro SR 400 Tablet:
Simvastatin's blood levels and effects may be greatly increased when combined with Itapro SR 400 Tablet.

How to manage the interaction:
Simvastatin and Itapro SR 400 Tablet may interact, but if prescribed by a doctor, they can be used together. Consult a doctor if you have side effects such unexplained pain in the muscles or tenderness, muscle weakness, fever or flu-like symptoms, or dark urine. Without consulting a doctor, never stop taking any medication.
ItraconazoleNisoldipine
Critical
How does the drug interact with Itapro SR 400 Tablet:
The blood levels and effects of nisoldipine may be greatly increased when used with Itapro SR 400 Tablet.

How to manage the interaction:
Nisoldipine and Itapro SR 400 Tablet may interact, but if prescribed by a doctor, they can be used together. Consult a physician if you have symptoms that include an irregular heartbeat, accumulation of fluid in legs or hands, or abnormally low blood pressure. Without consulting a doctor, never stop taking any medication.
ItraconazoleSolifenacin
Critical
How does the drug interact with Itapro SR 400 Tablet:
The blood levels and effects of solifenacin may be greatly increased when combined with Itapro SR 400 Tablet.

How to manage the interaction:
Solifenacin and Itapro SR 400 Tablet may interact, however, if recommended by a physician, they are safe to consume. Consult a doctor if you feel sleepy, or uneasy, have an irregular heartbeat, have blurry vision, have trouble urinating, have a dry mouth, a headache, have digestive problems, or have constipation. Without consulting a doctor, never stop taking any medication.
ItraconazoleDisopyramide
Critical
How does the drug interact with Itapro SR 400 Tablet:
Coadministration of Itapro SR 400 Tablet with Disopyramide can reduce the metabolism and increase the levels of Disopyramide in the body. This may increase the risk or severity of side effects like irregular heart rhythms.

How to manage the interaction:
Taking Itapro SR 400 Tablet with Disopyramide together is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of headaches, dizziness, irritation, confusion, chest pain or tightness, swelling, fatigue, palpitations, shortness of breath, or constipation, you should contact your doctor immediately. Do not stop using any medications without talking to your doctor.
ItraconazoleAlprazolam
Critical
How does the drug interact with Itapro SR 400 Tablet:
Alprazolam's blood levels may be significantly raised when combined with Itapro SR 400 Tablet.

How to manage the interaction:
Although combining Alprazolam and Itapro SR 400 Tablet may lead to an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you get extremely drowsy and your breathing becomes slow. Without consulting a doctor, never stop taking any medication.
ItraconazoleIsavuconazole
Critical
How does the drug interact with Itapro SR 400 Tablet:
The blood levels and effects of Isavuconazole may be significantly enhanced by taking Itapro SR 400 Tablet along with it.

How to manage the interaction:
Co-administration of Isavuconazole and Itapro SR 400 Tablet can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like nausea, vomiting, or diarrhoea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
ItraconazoleAvanafil
Critical
How does the drug interact with Itapro SR 400 Tablet:
Co-administartion of avanafil and Itapro SR 400 Tablet may considerably raise the blood levels of Avanafil.

How to manage the interaction:
Although combining avanafil and Itapro SR 400 Tablet may possibly lead to an interaction, they can be taken if prescribed by a doctor. Consult a physician if you develop any side effects, including priapism (prolonged and painful erection unrelated to sexual activity), low blood pressure, fainting, visual problems, including loss of vision, ringing in the ears, hearing loss, and low blood pressure. Without consulting a doctor, never stop taking any medication.
ItraconazoleErgotamine
Critical
How does the drug interact with Itapro SR 400 Tablet:
The blood levels and effects of ergotamine may be greatly increased when combined with Itapro SR 400 Tablet.

How to manage the interaction:
Ergotamine and Itapro SR 400 Tablet may interact, but if prescribed by a doctor, they can be used together. Consult a doctor if you experience a severe headache, shortness of breath, blurred vision, confusion, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discoloration of the fingers or toes, pale or cold skin, or chest pain or tightness. Without first consulting your doctor, never stop taking medicines.
ItraconazoleTolvaptan
Critical
How does the drug interact with Itapro SR 400 Tablet:
Co-administration of Tolvaptan and Itapro SR 400 Tablet may significantly raise Tolvaptan blood levels and effects.

How to manage the interaction:
There may be a possibility of interaction between Tolvaptan and Itapro SR 400 Tablet, but it can be taken if prescribed by a doctor. If you notice any of these signs -difficulty swallowing, trouble speaking, muscle weakness, trouble controlling body movements, confusion, mood changes, seizures, call a doctor right away. Do not stop using any medications without a doctor's advice.
ItraconazoleMethylergometrine
Critical
How does the drug interact with Itapro SR 400 Tablet:
Co-administration of Methylergometrine and Itapro SR 400 Tablet may increase the blood levels of Methylergometrine.

How to manage the interaction:
Methylergometrine and Itapro SR 400 Tablet may interact, but if prescribed by a doctor, they can be used together. Do not discontinue any medications without first consulting your doctor.

Drug-Food Interactions

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ITRACONAZOLE-400MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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ITRACONAZOLE-400MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Consuming Grapefruit, Grapefruit juice with Itapro SR 400 Tablet may impair the absorption of Itapro SR 400 Tablet, resulting in decreased antifungal effects. Avoid consuming Grapefruit and grapefruit juice with Itapro SR 400 Tablet.

Diet & Lifestyle Advise

  • Regularly change your socks and wash your feet. Avoid shoes that make your feet sweaty and hot.
  • Don't walk barefoot in wet places such as changing rooms and gym showers to prevent fungal infections.
  • Do not scratch the affected area of skin, as it can spread the infection to other body parts.
  • Avoid sharing towels, combs, bedsheets, shoes or socks with others.
  • Wash your bed sheets and towels regularly.

Habit Forming

No

Therapeutic Class

ANTIFUNGALS

Itapro SR 400 Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Avoid consumption of alcohol with Itapro SR 400 Tablet as it may increase the risk of liver problems and other adverse effects.

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Pregnancy

Unsafe

Itapro SR 400 Tablet is category C pregnancy drug and is unsafe for pregnant women as it may cause harm to the unborn baby. Therefore, inform your doctor if you are pregnant or planning for pregnancy before taking Itapro SR 400 Tablet.

bannner image

Breast Feeding

Caution

Itapro SR 400 Tablet is excreted in human milk and may harm the baby. Therefore, Itapro SR 400 Tablet is given to breastfeeding mothers only if doctor thinks benefits are greater than risks.

bannner image

Driving

Caution

Itapro SR 400 Tablet may cause dizziness, hearing loss, double or blurred vision in some people. Therefore, drive only if you alert after taking Itapro SR 400 Tablet.

bannner image

Liver

Caution

Take Itapro SR 400 Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

bannner image

Kidney

Caution

Take Itapro SR 400 Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

bannner image

Children

Unsafe

Itapro SR 400 Tablet is not recommended for children below 12 years as the safety and effectiveness were not established.

Have a query?

FAQs

Itapro SR 400 Tablet is used to treat fungal infections of the mouth, throat, toenails, fingernails or lungs. It works by inhibiting the production of ergosterol (a main component of cell membranes of fungi). Thereby killing fungi and clearing the fungal infection.

You are not recommended to take Itapro SR 400 Tablet with simvastatin as co-administration of these two medicines may cause muscle weakness, unexplained muscle pain or tenderness, dark coloured urine, fever or flu symptoms. However, please consult a doctor before using Itapro SR 400 Tablet with other medicines.

No, Itapro SR 400 Tablet is not recommended for use during pregnancy as it may cause harm to the fetus. Also, it is advised to use effective contraceptive measures while taking Itapro SR 400 Tablet and after 2 months of stopping treatment with Itapro SR 400 Tablet. However, please inform your doctor if you are pregnant, planning for pregnancy or breastfeeding before taking Itapro SR 400 Tablet.

Itapro SR 400 Tablet may cause temporary or permanent hearing loss in some people. It is not necessary for everyone taking Itapro SR 400 Tablet to experience this adverse effect. However, if you notice any changes in hearing, stop taking Itapro SR 400 Tablet and consult a doctor immediately.

You are advised to take antacids (drugs used to reduce acid in the stomach) such as omeprazole, pantoprazole and esomeprazole at least 1 hour before or 2 hours after taking Itapro SR 400 Tablet as co-administration of these medicines at the same time may reduce the effectiveness of Itapro SR 400 Tablet because antacids decrease the absorption and blood levels of Itapro SR 400 Tablet. However, please consult a doctor before taking other medicines with Itapro SR 400 Tablet.

Yes, fungal infection is a contagious skin condition which spreads from one person to another through direct skin to skin contact or by contact with contaminated soil or surfaces and infected animals. Therefore, it is recommended to avoid close direct contact until the infection is clear and avoid sharing things with the infected person as it can also spread the infection.

You are not recommended to stop taking Itapro SR 400 Tablet without consulting your doctor as it may cause recurring infection. Therefore, take Itapro SR 400 Tablet for as long as your doctor has prescribed it, and if you experience any difficulty while taking Itapro SR 400 Tablet, please consult your doctor.

Inform your doctor if you are sexually active and discuss effective contraception methods. Itapro SR 400 Tablet may reduce the effectiveness of oral contraceptive pills. Thus, you are advised to use barrier methods of contraception like condoms, if you are taking Itapro SR 400 Tablet.

Inform the doctor about your detailed medical and surgical history, if you have liver, kidney or heart disease or fits and if you are pregnant, breastfeeding or planning pregnancy. Inform your doctor if you are taking any other medicines including supplements or herbal products as Itapro SR 400 Tablet may interact with other medicines. Also, let your doctor know if you are stopping any medicine.

Itapro SR 400 Tablet contains Itraconazole, an antifungal that works by inhibiting the production of ergosterol (a main component of cell membranes of fungi). Thereby, weakens and damages the fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thus, it causes the main components of fungal cells to leak out, kill fungi, and clear the fungal infection.

Yes, you should swallow the capsule whole with a glass of water. Do not crush, chew or break it.

The side effects of Itapro SR 400 Tablet include nausea, headache, diarrhoea, stomach pain, fatigue (overtiredness), back pain, cough, and sore throat. If these side effects persist or worsen, please consult your doctor.

If you have taken overdose of Itapro SR 400 Tablet, please consult your doctor immediately.

Store Itapro SR 400 Tablet at room temperature. Protect from light and moisture. Keep out of reach and sight of children.

Country of origin

India

Manufacturer/Marketer address

Ajanta House, Charkop, Kandivli West, Mumbai 400 067, India.
Other Info - ITA0025

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Aug 6, 2025 | 11:31 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/022484s000lbl.pdf
  2. https://mims.com/malaysia/drug/info/itraconazole/patientmedicine/itraconazole%2B-%2Boral
  3. https://www.drugs.com/mtm/itraconazole.html

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