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compositionComposition:ISOPRENALINE-2MG
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Prescription Medicine
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Isolin Injection 1 ml is used to treat heart failure, shock, and irregular heartbeats. It contains Isoprenaline which works by stimulating certain receptors in the heart that increase the force and strength with which the heart beats. It also promotes blood flow. In some cases, this medicine may cause side effects such as headache, dizziness, restlessness, or sweating. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

ISOPRENALINE-2MG

Manufacturer/Marketer :

Samarth Life Sciences Pvt Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Isolin Injection 1 ml

Isolin Injection 1 ml is an emergency medicine given as an injection to treat dangerously slow heart rates and heart block. It works by stimulating the heart to beat faster and with more strength, which helps restore proper blood flow throughout your body during critical cardiac events. In certain emergency situations, it may also be used to treat severe breathing problems during anaesthesia or to manage specific types of shock.

Because this medicine is given directly into a vein or muscle, it is used on an as-needed basis in emergency situations or hospital clinics, rather than on a regular daily schedule at home. There are no food requirements when receiving this injection because of how it enters the body. While recovering, resting quietly and maintaining a stable fluid balance under medical supervision are key steps that support your treatment results.

Common side effects of Isolin Injection 1 ml include a fast heart rate, headache, shaking, and feeling warm or flushed. You must let your healthcare provider know immediately if you experience chest pain, an irregular heart rhythm, or severe dizziness while receiving this medicine. Your medical team will monitor you closely to manage any such symptoms quickly.

Before you are given this medicine, talk to your doctor if you have a history of high blood pressure, diabetes, coronary artery disease, or an overactive thyroid. Do not take this if you have a very fast heart rate or heart rhythm issues caused by digitalis toxicity. Your doctor will carefully review your medical history to ensure this medication is safe for you.

This medicine can interact with certain anaesthetics, blood pressure drugs, and other heart medications, which may increase your risk of severe heart rate changes. If you are pregnant, breastfeeding, or are an older adult, consult your healthcare team as special monitoring will be required during treatment to ensure your safety.

Uses of Isolin Injection 1 ml

The following are the common conditions for which Isolin Injection 1 ml may be prescribed:

  • Dangerously slow heart rate (bradycardia): Isolin Injection 1 ml helps by increasing the heart rate to ensure your vital organs receive an adequate supply of oxygen-rich blood.
  • Heart block: Isolin Injection 1 ml helps by improving the electrical conduction in the heart, allowing the upper and lower chambers to beat in proper coordination.
  • Shock: Isolin Injection 1 ml helps in certain cases of shock (like cardiogenic shock) by strengthening the heart’s pumping action and raising blood pressure to normal levels.
  • Severe bronchospasm during anaesthesia: Isolin Injection 1 ml helps by relaxing the airway muscles, making it easier to breathe if your lungs spasm during a surgical procedure.

Key Benefits

The following benefits highlight how Isolin Injection 1 ml provides rapid cardiovascular support, improves blood circulation, and helps stabilise life-threatening conditions:

  • Provides rapid emergency support: Because it is administered directly into the bloodstream, it acts quickly to increase heart rate and improve circulation during medical emergencies.
  • Improves blood flow to vital organs: By increasing the heart's pumping efficiency, it helps ensure that the brain, kidneys, and other vital organs receive enough oxygen-rich blood.
  • Relieves symptoms of a slow heart rate: It helps reduce symptoms such as fainting, severe dizziness, weakness, and fatigue caused by dangerously slow heart rhythms.
  • Supports recovery during critical illness: By stabilising heart function and circulation, it helps maintain vital body functions while the underlying condition is being treated.
Side effects of Isolin 1ml Inj
Here are the steps to manage medication-triggered tremors or involuntary shaking:
  • Notify your doctor immediately if you experience tremors or involuntary shaking after taking medication or adjusting your medication regimen.
  • Your doctor may adjust your medication regimen or recommend alternative techniques like relaxation, meditation, or journaling to alleviate tremor symptoms.
  • Your doctor may direct you to practice stress-reducing techniques, such as deep breathing exercises, yoga, or journaling.
  • Regular physical activity, such as walking or jogging, can help reduce anxiety and alleviate tremor symptoms.
  • Your doctor may recommend lifestyle changes, such as avoiding caffeine, getting enough sleep, and staying hydrated, to help manage tremors.
  • Maintain regular follow-up appointments with your doctor to monitor tremor symptoms and adjust treatment plans as needed.
Here are the steps to manage medication-triggered Nervousness:
  • Tell your doctor immediately if you experience symptoms of Nervousness, such as anxiety, jitteriness, or an increased heart rate, after taking medication or adjusting your medication regimen.
  • Your doctor may adjust your medication regimen to alleviate symptoms of Nervousness. This can include switching to a different medication, reducing the dosage, or temporarily stopping the medication. Your doctor may also recommend alternative techniques like relaxation, mindfulness meditation, or journaling. These techniques can help reduce anxiety and Nervousness.
  • Practice stress-reducing techniques, such as deep breathing exercises, yoga, or journaling, to help manage Nervousness.
  • Engage in regular physical activity, such as walking or jogging, to help reduce anxiety and improve mood.
  • Your doctor may advise considering cognitive-behavioural therapy (CBT) or other forms of talk therapy to address underlying anxiety or Nervousness.
  • You should maintain regular follow-up appointments with your doctor to monitor nervousness symptoms, adjust treatment plans as needed, and discuss any concerns or questions.
  • Limit caffeine intake as it can increase shakiness.
  • Manage stress with relaxation techniques like meditation or yoga.
  • Regular physical activity like walking or swimming can help improve muscle coordination.
  • Get enough sleep as lack of sleep may worsen tremors.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Isolin Injection 1 ml will be administered by the doctor or healthcare professional.
  • Do not self-administer.

How Isolin Injection 1 ml Works

Isolin Injection 1 ml contains isoprenaline, a non-selective beta-adrenergic agonist that stimulates beta receptors in the heart and lungs to improve heart function and breathing during medical emergencies. It works by stimulating beta-1 receptors in the heart, increasing both the heart rate and the force of each heartbeat. This helps improve cardiac output and ensures that vital organs receive an adequate supply of oxygen-rich blood. At the same time, it stimulates beta-2 receptors in the lungs, relaxing the smooth muscles surrounding the airways. This widens the air passages, making it easier to breathe during severe bronchospasm. Together, these actions help restore an adequate heart rate, improve blood circulation, and support breathing in emergency situations requiring immediate medical intervention.
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Alcohol

Caution

The interaction of Isolin Injection 1 ml with alcohol is unknown. Please consult a doctor before consuming alcohol while using Isolin Injection 1 ml.

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Pregnancy

Caution

Isolin Injection 1 ml is given to pregnant women only if benefits are greater than risks. Please consult a doctor.

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Breast Feeding

Caution

Isolin Injection 1 ml is given to breastfeeding mothers only if benefits are greater than risks. Please consult a doctor.

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Driving

Caution

Isolin Injection 1 ml may cause dizziness in some people. So, drive only if you are alert after taking Isolin Injection 1 ml.

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Liver

Caution

Take Isolin Injection 1 ml with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Isolin Injection 1 ml with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Isolin Injection 1 ml is not recommended for children below 18 years as the safety and effectiveness were not established.

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Heart

Caution

Isolin Injection 1 ml should be administered with caution in patients with heart problems. Please inform your doctor if you have any pre-existing heart problems before receiving Isolin Injection 1 ml.

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Geriatrics

Caution

Isolin Injection 1 ml should be administered with caution in elderly patients due to an increased risk of side effects. Seek medical advice if you have any concerns.

What if I have taken an overdose of Isolin Injection 1 ml

Since this medicine is given under strict clinical supervision with continuous monitoring, an overdose is rare. If an overdose does occur, it can cause a dangerously fast heart rate, high blood pressure, or chest pain. The medical team will immediately stop the injection and provide supportive treatments to bring your heart rate back to a safe level.

Diet & Lifestyle Advise

  • Avoid strenuous physical exertion: Rest quietly as your heart recovers from the emergency condition that required this medication. Avoid heavy lifting or sudden physical strain until your doctor clears you.
  • Eliminate stimulants: Avoid consuming caffeine, energy drinks, and tobacco products, as these can excessively raise your heart rate and worsen palpitations.
  • Maintain proper hydration: Follow your doctor’s specific instructions regarding daily fluid intake to help maintain healthy, stable blood pressure during your recovery.
  • Adopt a heart-healthy diet: Once you are stable, work with your healthcare team to build a balanced diet low in sodium and saturated fats to support your long-term cardiovascular health.
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How Soon It Starts Working

The time required for Isolin Injection 1 ml to start to work: The time required for Isolin Injection 1 ml to show its action is unknown. The time for which the effects of Isolin Injection 1 ml last: The effect of Isolin Injection 1 ml lasts for 10 to 15 minutes.

What if you forget to take Isolin Injection 1 ml

Because this medication is administered by healthcare professionals in a hospital or clinical setting, a missed dose is highly unlikely. If a scheduled infusion is delayed or interrupted, your medical team will adjust the delivery rate to ensure your heart rate remains stable.

Storage

•Isolin Injection 1 ml injections must be stored at controlled room temperature, between 15°C and 30°C (59°F to 86°F). •Do not freeze this medication, and keep the vials inside their original carton to protect them from direct light.

Drug Warnings

  • Inspect the medicine before use: Always check the solution inside the vial or infusion bag before administration. It should be completely clear and colourless. Do not use the medicine if the solution appears pink, brown, cloudy, or contains any visible particles.
  • Ensure continuous heart monitoring: Your heart rhythm should be continuously monitored with an ECG machine while the infusion is running to detect any sudden or abnormal rhythm changes immediately.
  • Report injection site problems immediately: Inform your nurse or doctor if you experience burning, stinging, coldness, pain, or swelling around the injection site, as these may indicate leakage of the medicine into surrounding tissues.
  • Monitor blood sugar levels if you have diabetes: Isolin Injection 1 ml may temporarily increase blood glucose levels. Your healthcare team may need to monitor your sugar levels more frequently and adjust your diabetes treatment if required.
  • Inform your anaesthesiologist before surgery: Tell your anaesthesiologist if you have received Isolin Injection 1 ml, as certain anaesthetic gases may interact with this medicine and increase the risk of irregular heart rhythms.

Drug-Drug Interactions

verifiedApollotooltip

The following medicines may interact with Isolin Injection 1 ml and affect its safety or effectiveness. Always inform your doctor about all medications you are receiving before treatment:

  • Beta-blockers (such as metoprolol or propranolol): These medicines may block the effects of Isolin Injection 1 ml, reducing its ability to increase heart rate and improve heart function.
  • Inhaled anaesthetics (such as halothane): Using these medicines together may increase the risk of serious irregular heart rhythms during treatment.
  • Other heart stimulants or decongestants: Combining these medicines with Isolin Injection 1 ml may excessively increase heart rate, blood pressure, and strain on the heart.
IsoprenalineMifepristone
Severe
IsoprenalineHaloperidol
Severe

Drug-Drug Interactions

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IsoprenalineMifepristone
Severe
How does the drug interact with Isolin 1ml Inj:
Co-administration of Isolin 1ml Inj with mifepristone can increase the risk of irregular heart rhythms.

How to manage the interaction:
Co-administration of Isolin 1ml Inj with Mifepristone can result in an interaction, it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not discontinue any medications without consulting a doctor.
IsoprenalineHaloperidol
Severe
How does the drug interact with Isolin 1ml Inj:
Co-administration of Isolin 1ml Inj and Haloperidol can increase the risk of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Co-administration of Isolin 1ml Inj and Haloperidol can lead to an interaction, but it can be taken if your doctor advises. However, contact your doctor immediately if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting. Do not discontinue any medications without consulting your doctor.
IsoprenalineZiprasidone
Severe
How does the drug interact with Isolin 1ml Inj:
Co-administration of Isolin 1ml Inj with Ziprasidone can reduce the therapeutic effectiveness of Isolin 1ml Inj.

How to manage the interaction:
Co-administration of Isolin 1ml Inj with Ziprasidone can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
IsoprenalineClozapine
Severe
How does the drug interact with Isolin 1ml Inj:
Taking Isolin 1ml Inj and Clozapine may increase the effect of irregular heart rhythm that can be serious.

How to manage the interaction:
Taking Isolin 1ml Inj with Clozapine together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you experience any of the following symptoms, please call a doctor right away: sudden dizziness, feeling lightheaded, fainting, difficulty breathing, or heart palpitations. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

verifiedApollotooltip

No clinically significant food interactions are known with Isolin Injection 1 ml when used as directed.

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[SYMPATHOMIMETICS]

FAQs

Isolin Injection 1 ml contains Isoprenaline that works by stimulating certain receptors in the heart that increases the force and strength at which the heartbeats. Thus, it allows pumping the blood effectively around the body in conditions such as heart failure.
You are recommended to avoid excessive intake of caffeine-containing foods such as tea, chocolate, or colas with Isolin Injection 1 ml as they may increase the severity of Isolin Injection 1 ml side effects.
Isolin Injection 1 ml is not recommended for patients suffering from a rapid, irregular heartbeat as it may worsen the condition. Therefore, if you have tachyarrhythmia (rapid irregular heartbeat), inform your doctor before taking Isolin Injection 1 ml.
You are not recommended to stop taking Isolin Injection 1 ml without consulting your doctor as it may worsen the condition. Therefore, take Isolin Injection 1 ml for as long as your doctor has prescribed it, and if you experience any difficulty while taking Isolin Injection 1 ml, please consult your doctor.
No, Isolin Injection 1 ml does not have any addictive or habit-forming potential.
Isolin Injection 1 ml causes side effects such as headache, dizziness, restlessness, sweating, tremors, palpitations (the sensation that the heart is racing) and flushing (warmth and reddening of face, and neck). Please, consult a doctor immediately if any of these side effects persist longer.
Isolin Injection 1 ml is primarily used in emergency clinical settings to treat dangerously slow heart rates, specific types of heart block, and shock. It works by stimulating your heart to beat faster and pump blood more effectively. Talk to your doctor if you have questions about your treatment plan.
This medicine is administered as an injection or a continuous fluid drip (infusion) directly into a vein, or occasionally as an injection into a muscle. It is given only by trained healthcare professionals in a hospital setting where your vitals can be closely monitored. Talk to your doctor for more details.
This medicine is typically reserved for critical, life-threatening situations where the benefits outweigh potential risks to the baby. If you are pregnant, your healthcare team will carefully evaluate the clinical situation and monitor both you and your baby closely. Talk to your doctor about your health history.
If you have high blood pressure, this medication must be used with extreme caution because it can temporarily elevate your blood pressure further. Your healthcare team will closely watch your blood pressure levels during administration. Talk to your doctor if you have concerns about your blood pressure.
This medicine acts very rapidly on the heart and can cause sudden changes in your heart rate and rhythm. Continuous ECG monitoring ensures that the medical team can adjust your dose instantly to keep you safe and stable. Talk to your doctor if you want to learn more about the monitoring process.
Tell your nurse or doctor immediately if you feel pain, burning, swelling, or coldness near the injection site. This can be a sign that the medicine has leaked outside the vein, which requires prompt medical attention. Talk to your doctor or nurse if you feel any discomfort.
Yes. Isolin Injection 1 ml can interact with several medicines, especially beta-blockers (such as metoprolol), certain anaesthetics, and other heart medications. These interactions may reduce the effectiveness of Isolin Injection 1 ml or increase the risk of side effects. Make sure your healthcare team knows about all the medicines you are taking, including prescription medicines, over-the-counter products, and herbal supplements. Talk to your doctor or pharmacist for more information.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Drugs.com Clinical Review Team. Isoproterenol Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  2. Central Drugs Standard Control Organisation (CDSCO). [Accessed on 19 Mar. 2019]Check here
  3. Ministry of Health and Family Welfare. National Formulary of India (NFI) 2021. 6th ed. New Delhi, India: IPC; 2021. Clinical Drug Monographs: Isolin 2Mg Injection

Country of origin

India

Manufacturer/Marketer address

Samarth House, 168, Bangur Nagar, Off Link Road, Near Ayappa Temple & Kallol Kali Temple, Goregaon (W), Mumbai - 400 090.
Other Info - ISO0010
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