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Isocold Syrup is used to treat symptoms of the common cold and allergies like sneezing, runny/stuffy nose, fever, headache, body pains, congestion, or watery eyes in children. It also helps reduce nasal congestion and sinus pressure by shrinking swollen nasal blood vessels.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

CHLORPHENIRAMINE MALEATE-2MG+PHENYLEPHRINE HYDROCHLORIDE-5MG

Manufacturer/Marketer :

Gufic Bioscience Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Isocold Syrup

Isocold Syrup is a combination medicine used to treat symptoms of the common cold, allergies, and upper respiratory tract infections in children. It helps relieve distressing symptoms like a blocked nose, runny nose, sneezing, and watery eyes. By targeting both allergy symptoms and nasal congestion, it helps your child breathe easier and rest comfortably.

This medicine is typically given to your child as directed by your doctor, usually spaced out evenly throughout the day. It can be taken with or without food, though giving it with food may help prevent mild stomach upset. Along with this medicine, keeping your child hydrated and using a humidifier can significantly improve recovery.

While taking Isocold Syrup, some children may experience mild side effects, such as sleepiness or a dry mouth. These are usually harmless and go away on their own. However, if you notice any unusual restlessness, a very fast heartbeat, or difficulty breathing, you should stop the medication and consult your doctor immediately.

Do not give this medicine to your child if they have a known allergy to similar medicines or if they are taking certain medications for neurological conditions. It is important to talk to your doctor before starting this medicine if your child has pre-existing conditions like asthma, heart problems, or thyroid disorders.

This medicine can interact with other cough, cold, or allergy preparations, which can increase the risk of accidental overdose. It should not be used alongside other sedating medicines. Since this is a pediatric formulation, it is not intended for use in pregnant, breastfeeding, or elderly individuals.

Uses of Isocold Syrup

Isocold Syrup is used in the treatment of the Common cold and Allergies. The detailed uses of Isocold Syrup are as follows:

  • Common Cold Symptoms: It effectively relieves runny nose, constant sneezing, and watery eyes caused by seasonal colds.
  • Nasal Congestion: It clears the blockage in the nasal passages, reducing stuffiness so your child can breathe more comfortably.
  • Allergic Rhinitis: It eases allergic symptoms triggered by dust, pollen, or pet dander.

Key Benefits

  • Provides quick relief from cold and allergy symptoms, helping your child feel better sooner.
  • Clears a blocked nose, making breathing easier and more comfortable.
  • Improves sleep and feeding by reducing nasal congestion and discomfort.
  • Reduces sneezing and a runny nose, helping your child stay more comfortable.
  • Helps prevent throat irritation caused by post-nasal drip.
  • Supports faster recovery by soothing irritated airways and reducing coughing episodes.
Side effects of Isocold Syrup 60 ml
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Directions for Use

  • Isocold Syrup can be taken with or without food, or as advised by a doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Check the label for directions and give the prescribed dose to your child by mouth using the dropper.
  • Shake the bottle well before each use.

How Isocold Syrup Works

This medicine contains two active ingredients that work together to relieve cold and allergy symptoms. •Chlorpheniramine is an antihistamine. It blocks a natural chemical messenger in the body called histamine, which is responsible for triggering allergy symptoms like sneezing, watery eyes, and a runny nose. •Phenylephrine is a nasal decongestant. It works by narrowing the swollen blood vessels inside your child's nasal passages. This reduces swelling and congestion, opening up the airways and making it much easier for your child to breathe through their nose.
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Alcohol

Not applicable

-

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Pregnancy

Not applicable

-

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Breast Feeding

Not applicable

-

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Driving

Not applicable

-

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Liver

Consult your doctor

If your child has a history of liver problems, please inform your doctor.

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Kidney

Consult your doctor

If your child has a history of kidney diseases, please inform your doctor.

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Children

Safe if prescribed

Use Isocold Syrup for children as advised by the doctor.

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Heart

Caution

Isocold Syrup should be avoided in children with heart problems, as Phenylephrine hydrochloride can raise blood pressure and heart rate, and Chlorpheniramine maleate may cause drowsiness or agitation. Always consult a paediatrician before use, especially if your child has any cardiac condition.

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Geriatrics

Not applicable

Isocold Syrup is specifically for children's use and is not meant for geriatric patients.

What if I have taken an overdose of Isocold Syrup

If you suspect your child has taken more than the prescribed amount of Isocold Syrup, seek immediate medical attention or contact a poison control center. Symptoms of an overdose may include extreme sleepiness, severe dizziness, restlessness, or a rapid heart rate.

Diet & Lifestyle Advise

  • Keep your child well-hydrated by offering plenty of fluids like water, warm soups, or clear broths, which help thin and loosen mucus.
  • Use a cool-mist humidifier in your child's bedroom to add moisture to the air and ease breathing during the night.
  • Elevate your child's head slightly with an extra pillow while resting (only for older children; do not use pillows for infants) to help nasal secretions drain naturally.
  • Gently clear your child's nose using saline nasal drops or a bulb syringe before administering the medicine to help them breathe easier.
  • Keep your child's environment free from known allergy triggers, such as tobacco smoke, heavy dust, strong perfumes, and pet dander.
health query

Have a query?

How Soon It Starts Working

  • The time required for Isocold Syrup to start to work: Isocold Syrup ideally shows its action within a few minutes after administration.
  • The time for which the effects of Isocold Syrup last: The duration of action for Isocold Syrup is clinically unknown.

What if you forget to take Isocold Syrup

If you miss a dose, give it as soon as you remember. However, if it is almost time for the next scheduled dose, skip the missed dose and continue with the regular schedule. Do not give a double dose to make up for a missed one.

Storage

•Store Isocold Syrup at room temperature, ideally below 30°C.

Drug Warnings

  • Always use the measuring device that comes in the package; do not guess the dose using a household teaspoon.
  • Check the liquid before each use; if you notice any unusual cloudiness, floating particles, or discoloration, do not use it and consult your pharmacist.
  • Do not use this medicine if your child is currently taking, or has taken within the last 14 days, medicines for depression known as MAO inhibitors.
  • Read the labels of all other over-the-counter cold and cough medicines carefully to ensure they do not contain overlapping active ingredients, which can lead to accidental toxicity.
  • Monitor your child closely during the first few doses, as some children may experience a paradoxical reaction where they become hyperactive or restless instead of sleepy.

Drug-Drug Interactions

verifiedApollotooltip
  • MAO Inhibitors: May lead to a severe, sudden rise in blood pressure if used together.
  • Other Antihistamines: Can increase sleepiness and the risk of dry mouth or constipation.
  • Sedatives or Sleep Medications: May cause extreme drowsiness and slowed breathing when taken together.
Chlorpheniramine + PhenylephrineFurazolidone
Critical
Chlorpheniramine + PhenylephrineIsocarboxazid
Critical

Drug-Drug Interactions

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Chlorpheniramine + PhenylephrineFurazolidone
Critical
How does the drug interact with Isocold Syrup 60 ml:
Taking Isocold Syrup 60 ml with Furazolidone can cause an increase in high blood pressure.

How to manage the interaction:
Taking Isocold Syrup 60 ml with Furazolidone is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden headaches, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sweating, lightheadedness, fainting, sudden numbness or weakness (especially on one side of the body), speech difficulties, or fever, consult a doctor immediately. It is advised to use Phenylephrine only after 14 days of stopping Furazolidone. Do not stop using any medications without a doctor’s advice
Chlorpheniramine + PhenylephrineIsocarboxazid
Critical
How does the drug interact with Isocold Syrup 60 ml:
Co-administration of Isocold Syrup 60 ml with Isocarboxazid can result in extremely high blood pressure.

How to manage the interaction:
Although taking Isocold Syrup 60 ml together with Isocarboxazid is not recommended as it can result in an interaction, it can be taken if prescribed by a doctor. However, if you develop a sudden, severe headache, blurred vision, confusion, chest pain, nausea, or vomiting, sudden numbness or weakness (particularly on one side of the body), difficulty speaking, fever, sweating, lightheadedness, or fainting, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
Chlorpheniramine + PhenylephrineSelegiline
Critical
How does the drug interact with Isocold Syrup 60 ml:
Co-administration of Isocold Syrup 60 ml with Selegiline can raise blood pressure.

How to manage the interaction:
Taking Isocold Syrup 60 ml with Selegiline is not recommended, it can be taken together if prescribed by a doctor. However, consult a doctor immediately if you experience any symptoms such as severe headache, blurred vision, confusion, fits, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and/or fainting. Do not discontinue any medications without consulting a doctor.
Chlorpheniramine + PhenylephrineMethylene blue
Critical
How does the drug interact with Isocold Syrup 60 ml:
Taking Isocold Syrup 60 ml with Methylene blue can cause an increase in high blood pressure.

How to manage the interaction:
Taking Isocold Syrup 60 ml with Methylene blue is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden headaches, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sweating, lightheadedness, fainting, sudden numbness or weakness (especially on one side of the body), speech difficulties, or fever, consult a doctor immediately. It is advised to use Phenylephrine only after 14 days of stopping Methylene blue. Do not stop using any medications without a doctor’s advice.
Chlorpheniramine + PhenylephrinePotassium citrate
Critical
How does the drug interact with Isocold Syrup 60 ml:
Co-administration of Isocold Syrup 60 ml with potassium citrate can make potassium more irritating to your upper intestine and stomach.

How to manage the interaction:
Taking Isocold Syrup 60 ml with Potassium citrate is not recommended as it can lead to an interaction, it can be taken if prescribed by a doctor. However, if you experience any symptoms such as severe stomach pain, bloating, lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
Chlorpheniramine + PhenylephrineSevoflurane
Critical
How does the drug interact with Isocold Syrup 60 ml:
Co-administration of Isocold Syrup 60 ml with Isoflurane makes phenylephrine more harmful. Additionally, phenylephrine reduces sleepiness, and chlorpheniramine and sevoflurane promote sleepiness.

How to manage the interaction:
Co-administration of Isocold Syrup 60 ml with Sevoflurane is not recommended as it can result in an interaction, but it can be taken if prescribed by a doctor. However, if you experience severe headaches, chest pain, dizziness, difficulty breathing, nausea, vomiting, blurred vision, or anxiety, consult a doctor. Do not stop using any medications without a doctor’s advice. Do not discontinue any medications without a doctor's advice.
Chlorpheniramine + PhenylephrineTranylcypromine
Critical
How does the drug interact with Isocold Syrup 60 ml:
Taking Isocold Syrup 60 ml with Tranylcypromine can increase the risk of high blood pressure.

How to manage the interaction:
Taking Isocold Syrup 60 ml with Tranylcypromine is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience severe headaches, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and fainting. Do not discontinue any medications without consulting a doctor.
Chlorpheniramine + PhenylephrinePropofol
Critical
How does the drug interact with Isocold Syrup 60 ml:
Taking Isocold Syrup 60 ml with Propofol lowers metabolism, which raises phenylephrine levels. Additionally, it can increase or decrease sleepiness when taken together.

How to manage the interaction:
Taking Isocold Syrup 60 ml with Propofol is not recommended, as it leads to an interaction, but it can be taken if prescribed by a doctor. Do not discontinue the medications without consulting a doctor.
Chlorpheniramine + PhenylephrineLinezolid
Critical
How does the drug interact with Isocold Syrup 60 ml:
Co-administration of Isocold Syrup 60 ml together with Linezolid can lead to side effects like increased blood pressure.

How to manage the interaction:
Taking Isocold Syrup 60 ml together with Linezolid is not recommended as it can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience severe headaches, chest pain, dizziness, difficulty breathing, nausea, vomiting, blurred vision, or anxiety, consult a doctor. Do not stop using any medications without a doctor’s advice.
Chlorpheniramine + PhenylephrineHalothane
Severe
How does the drug interact with Isocold Syrup 60 ml:
Co-administration of Isocold Syrup 60 ml with Halothane may increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although taking Isocold Syrup 60 ml together with Halothane can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience any symptoms like lightheadedness, fainting, irregular heartbeat, or dizziness, consult a doctor. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip

  • No clinically significant food interactions are known with Isocold Syrup when used as directed. 

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIALLERGIC]

FAQs

Isocold Syrup is used to treat the common cold and allergies.
Isocold Syrup contains Phenylephrine hydrochloride and Chlorpheniramine maleate. Phenylephrine hydrochloride is a decongestant that works by contracting and narrowing the blood vessels. Thereby providing relief from congestion and decreasing mucus production. Chlorpheniramine maleate is an antihistamine (anti-allergic drug) that works by blocking the action of histamine, a substance responsible for causing allergic reactions. It helps relieve symptoms of allergies such as sneezing, running nose, watery eyes, itching, swelling, and congestion or stiffness.
Do not stop giving Isocold Syrup to your child without consulting your doctor, as it may worsen the condition or cause recurring symptoms. Therefore, use Isocold Syrup for as long as your doctor has prescribed it, and if your child experiences any difficulty while taking Isocold Syrup, please consult your doctor.
When using Isocold Syrup, be sure to follow your doctor's advice and inform them about any medical conditions, allergies, or medications your child is taking. Do not administer more than the prescribed dose or for a longer duration.
Isocold Syrup is a medication intended for children. Note that this medication is not for adults. If your child has high blood pressure, discuss their condition with your doctor before administering it. Follow your doctor's guidance and advice to ensure the safe and effective use of Isocold Syrup for your child.
Do not use a higher dose of Isocold Syrup than your doctor recommends. Using more than the prescribed dose can lead to serious side effects and may cause harm. Always follow your doctor's instructions and take the medication as directed. If you have any concerns, consult your doctor.
Store Isocold Syrup in a cool and dry place away from sunlight, out of the sight and reach of children.
Do not give Isocold Syrup to your child with other medications for colds or allergies unless advised by the doctor. Combining medications can be risky, especially for children.
Common side effects of Isocold Syrup may include drowsiness, nervousness, headache, dizziness, insomnia (difficulty falling or staying asleep), blurred vision, constipation and dry mouth. Most of these side effects of Isocold Syrup do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
Isocold Syrup should not be given to newborns or very young infants unless specifically prescribed by a doctor. Young children may be more sensitive to the effects of cough and cold medicines. Consult your pediatrician before giving Isocold Syrup to an infant.
Yes, this medicine can be taken with or without food. However, if your child has a sensitive stomach, giving it with a meal or milk can help prevent mild stomach upset. Talk to your doctor for further guidance.
Do not give another dose immediately, as it is difficult to know how much medicine was absorbed. Giving another dose right away could cause an accidental overdose. Talk to your doctor or pharmacist for guidance on when to give the next dose.
Generally, yes, but you must carefully check the labels of both products to ensure there are no overlapping active ingredients. To keep your child safe, always talk to your doctor or pharmacist before combining medications.
Sometimes, antihistamines can cause a paradoxical reaction in young children, making them excited, restless, or hyperactive instead of drowsy. This is a known effect; if it happens, talk to your doctor.
Do not use standard kitchen spoons, as they are not accurate and can lead to under-dosing or over-dosing. Instead, visit your local pharmacy to get a calibrated oral syringe or replacement dropper. Talk to your doctor or pharmacist if you are unsure how to use it.

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Country of origin

India

Manufacturer/Marketer address

37,1St Floor, Kamala Bhavan Ii, Swami Nityanand Road, Andheri (East), Mumbai - 400 069. (India)
Other Info - ISO0282
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