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compositionComposition:ISEPAMICIN-200MG
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Isep-200mg Injection 2ml is used to treat bacterial infections such as lower respiratory tract infections, intra-abdominal infections, urinary tract infections, skin and soft tissue infections, and septicaemia. It contains Isepamicin, which inhibits bacterial protein synthesis by binding to 30s and 50s ribosomal subunits in susceptible bacteria. Isep-200mg Injection 2ml may cause side effects such as electrolyte disturbances, ototoxicity (hearing or balance problems), and nephrotoxicity (rapid deterioration of kidney function).

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

ISEPAMICIN-200MG

Manufacturer/Marketer :

Fusion Health Care Pvt Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Isep-200mg Injection 2ml

This prescription-only, hospital-grade medicine is given as an injection, usually once or twice a day, and should be strictly administered under professional medical supervision.

Isep-200mg Injection 2ml is used to treat serious bacterial infections caused by susceptible bacteria. It works by stopping the bacteria from making essential proteins, which prevents their growth and helps eliminate the infection.

Because it is injected directly into your vein or muscle, it does not depend on food intake, so you do not need to worry about taking it with meals. To help your body recover and support your kidneys while using this medicine, it is highly recommended to drink plenty of fluids throughout the day.

While using Isep-200mg Injection 2ml, some people may experience mild side effects such as pain at the injection site, nausea, or a mild skin rash. However, you must contact your doctor immediately if you notice more serious signs, such as changes in your hearing, ringing in your ears, dizziness, or a decrease in how much you urinate.

Before starting treatment, review your medical history carefully. Who should NOT take Isep-200mg Injection 2ml: Do not receive this medicine if you have a known history of severe allergic reactions (hypersensitivity) to Isep-200mg Injection 2ml or other aminoglycoside antibiotics. It is generally avoided during pregnancy unless no safer alternative exists, as it poses risks of fetal ear and kidney toxicity.

Use with extreme caution if you have kidney impairment, hearing disorders, or neuromuscular conditions such as myasthenia gravis. Aminoglycosides can also pass into breast milk, requiring careful risk evaluation or temporary pauses in breastfeeding during treatment. 
 

Uses of Isep-200mg Injection 2ml

Isep-200mg Injection 2ml is used to treat serious bacterial infections. The detailed uses of Isep-200mg Injection 2ml are as follows:

  • Complicated urinary tract infections (UTIs): Isep-200mg Injection 2ml helps by targeting and eliminating resistant bacteria in the kidneys and bladder.
  • Severe respiratory tract infections: Isep-200mg Injection 2ml helps clear deep-seated bacterial infections in the lungs, such as severe pneumonia.
  • Blood poisoning (septicemia): Isep-200mg Injection 2ml works rapidly in the bloodstream to fight off severe, life-threatening infections where bacteria have spread into the blood.
  • Intra-abdominal infections: Isep-200mg Injection 2ml helps treat serious infections inside the abdomen when combined with other appropriate medicines.
     

Key Benefits

Isep-200mg Injection 2ml provides important benefits in the treatment of serious bacterial infections. The key benefits of Isep-200mg Injection 2ml include:

  • Rapid Action: This medicine provides rapid action against severe, hard-to-treat bacterial infections, helping you begin feeling better within a few days of starting treatment.
  • Effective for Resistant Infections: It offers a highly reliable option for infections that do not respond to standard oral antibiotics, promoting a faster pathway to recovery.
  • Symptom Relief: It helps reduce severe symptoms like high fever, body aches, and localised pain caused by spreading bacteria.
  • Direct Delivery: Because it is given directly into the vein (intravenously) or muscle (intramuscularly), the medicine reaches the infection site quickly and efficiently without having to pass through your digestive system.
     

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication.
  • Isep-200mg Injection 2ml will be administered by a healthcare professional.
  • Do not self-administer it.

How Isep-200mg Injection 2ml Works

Isep-200mg Injection 2ml contains isepamicin, an aminoglycoside antibiotic that works by binding directly to the 30S subunit of the bacterial ribosome (the part of the bacterial cell responsible for building proteins). It is particularly effective against tough Gram-negative bacteria (such as Pseudomonas aeruginosa and Enterobacteriaceae species), including resistant strains that do not respond to standard treatments. By directly killing these bacteria, Isep-200mg Injection 2ml halts the spread of the infection and allows your body's natural defence system to clear it out completely.
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Alcohol

Consult your doctor

It is not known if alcohol interacts with Isep-200mg Injection 2ml. Please consult the doctor.

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Pregnancy

Caution

Isep-200mg Injection 2ml may not be recommended during pregnancy. If you are pregnant or planning pregnancy, inform the doctor before receiving Isep-200mg Injection 2ml.

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Breast Feeding

Consult your doctor

Limited information is available. If you are breastfeeding, inform the doctor before receiving Isep-200mg Injection 2ml.

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Driving

Consult your doctor

It is unknown if Isep-200mg Injection 2ml affects your ability to drive. Drive only if you are alert.

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Liver

Caution

If you have a history of liver problems, inform the doctor before receiving Isep-200mg Injection 2ml.

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Kidney

Caution

If you have a history of kidney problems, inform the doctor before receiving Isep-200mg Injection 2ml.

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Children

Consult your doctor

Limited information is available. Please consult the doctor if you have any concerns regarding the usage of Isep-200mg Injection 2ml in children.

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Heart

Caution

Isep-200mg Injection 2ml should be used with caution in individuals with heart problems due to its potential nephrotoxic and neuromuscular side effects. A thorough cardiac and renal evaluation is essential before initiating therapy to avoid complications.

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Geriatrics

Caution

Isep-200mg Injection 2ml should be avoided in geriatric patients due to increased risks of nephrotoxicity, ototoxicity, and drug interactions. Close monitoring and alternative antibiotics are recommended to minimize adverse effects.

What if I have taken an overdose of Isep-200mg Injection 2ml

If you suspect an overdose or experience severe dizziness, hearing changes, or sudden weakness after an injection, seek immediate medical attention.

Diet & Lifestyle Advise

  • Stay well-hydrated: Drink plenty of water throughout your treatment course (unless your doctor tells you otherwise) to help protect your kidneys and flush the medicine through your system safely.
  • Avoid kidney-straining substances: Limit your intake of caffeine and avoid alcohol during treatment, as these can dehydrate your body and put extra stress on your kidneys.
  • Eat light, balanced meals: If you experience mild nausea from the injection, eat smaller, more frequent meals and avoid highly spiced or greasy foods.
  • Rest and recover: Allow your body plenty of rest while fighting off a severe bacterial infection to help your immune system work efficiently.

 

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How Soon It Starts Working

The time required for Isep-200mg Injection 2ml to start to work: Isep-200mg Injection 2ml ideally shows its action within 30 to 60 minutes after administration. The time for which the effects of Isep-200mg Injection 2ml last: The duration of action for Isep-200mg Injection 2ml is unknown.

What if you forget to take Isep-200mg Injection 2ml

Since Isep-200mg Injection 2ml is usually given by a healthcare provider, missing a dose is uncommon. However, if you are treating yourself at home and miss a dose, contact your doctor or pharmacist immediately for instructions. Do not inject a double dose to make up for a missed one.

Storage

• Store Isep-200mg Injection 2ml vials at controlled room temperature, ideally below 30°C (86°F).
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Keep Refrigerated. Do not freeze.

Drug Warnings

  • Inspect the liquid before use: Always check the vial or bag before injection. The liquid should be clear and colourless to pale yellow. Do not use it if you see particles, cloudiness, or discolouration.
  • Rotate injection sites: If you are receiving intramuscular injections, rotate the injection site each time to minimise muscle pain, bruising, or tissue damage.
  • Monitor kidney function: Your doctor may schedule regular blood tests to check your kidney function and monitor the level of the drug in your body. Make sure you do not miss these appointments.
  • Report hearing changes early: Notify your doctor immediately if you experience even minor changes in your hearing or balance; while hearing changes can occur, your healthcare team will monitor you closely to catch and manage any issues early.
  • Ensure needle safety: Always discard used needles and syringes immediately into a puncture-proof sharps container. Never recap a used needle.
     

Drug-Drug Interactions

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  • Kidney- or Hearing-Damaging Medicines: Combining Isep-200mg Injection 2ml with other medicines that can damage the kidneys or hearing (such as amphotericin B, cisplatin, or certain strong water pills like furosemide) can significantly increase the risk of kidney and ear damage.
  • Neuromuscular Blocking Agents: Using this medicine alongside neuromuscular blocking agents (muscle relaxants used during surgery) can increase the risk of severe muscle weakness and breathing difficulties.
     
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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No clinically significant food interactions are known with Isep-200mg Injection 2ml when used as directed.

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIBIOTICS]

FAQs

Isep-200mg Injection 2ml is used to treat bacterial infections.
Isep-200mg Injection 2ml works by inhibiting bacterial protein synthesis. Thereby, it helps treat bacterial infections.
Isep-200mg Injection 2ml may cause ototoxicity (hearing or balance problems). If you have hearing problems or any concerns regarding this, please consult the doctor.
Isep-200mg Injection 2ml may be used to treat lower respiratory tract infections (LRTI). However, if you have any concerns, consult the doctor.
Isep-200mg Injection 2ml is administered by a healthcare professional through an intravenous (IV) infusion or slow injection. Do not self-administer Isep-200mg Injection 2ml.
As Isep-200mg Injection 2ml is administered by the doctor, it is unlikely to use a higher than the recommended dose. The doctor will administer a suitable dose based on your medical condition.
Yes, Isep-200mg Injection 2ml is effective in treating bacterial infections such as lower respiratory tract infections, intra-abdominal infections, urinary tract infections, skin and soft tissue infections and septicaemia.
Consult the doctor if you do not get better even after completing the course of treatment of if you condition worsens during treatment with Isep-200mg Injection 2ml.
Do not discontinue Isep-200mg Injection 2ml without consulting your doctor. To treat your condition effectively, complete the duration of treatment as prescribed by the doctor.
Isep-200mg Injection 2ml may cause side effects such as electrolyte disturbances, ototoxicity (hearing or balance problems), and nephrotoxicity (rapid deterioration of kidney function). Talk to the doctor if you experience any side effects.
Do not stop the injection on your own—notify your doctor or nurse immediately so they can evaluate your symptoms and adjust your treatment safely. While hearing changes or dizziness can occur, your care team is trained to monitor and address these signs quickly to protect your hearing. Talk to your doctor.
Your doctor will order regular blood tests to check your kidney function and to measure the exact amount of the medicine in your bloodstream. This helps ensure you are receiving a safe and effective dose. Talk to your doctor.
Isep-200mg Injection 2ml is generally avoided during pregnancy due to potential risks to the developing baby, such as inner ear and kidney toxicity. Small amounts can also pass into breast milk, which may affect the infant's gut flora. If you are pregnant, planning to become pregnant, or nursing, consult your doctor to weigh the risks and discuss safer alternatives or temporary pauses in breastfeeding.
No, Isep-200mg Injection 2ml is an antibiotic that only works against bacterial infections. It will not cure viral infections such as the common cold, flu, or COVID-19. Talk to your doctor.
It is highly recommended to avoid alcohol while taking Isep-200mg Injection 2ml. Alcohol can cause dehydration, which can put additional stress on your kidneys while they are clearing the medicine from your system. Talk to your doctor.
Mild pain or redness at the injection site can sometimes occur. However, if the pain worsens, or if you notice warmth, spreading redness, or pus, contact your healthcare provider immediately, as this could indicate an infection. Talk to your doctor.

Disclaimer

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Country of origin

India

Manufacturer/Marketer address

Fusion House, Plot No. 22, H.No 8-2-350/B, Road No. 3, Banjara Hills, Hyderabad, Telangana-500034
Other Info - ISE0007
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