Apollo
logo
Select Delivery Location
compositionComposition:RALTEGRAVIR-400MG
prescription
Prescription Medicine
info
Best Price

₹10 with coupons & bank offers*

View

Isentress 400mg Tablet belongs to the class of antiretroviral drugs used in the treatment of HIV infection. This medicine work by inhibiting the replication of HIV by blocking DNA integration into new cells. Common side effects include dizziness, headache, diarrhoea, nausea, vomiting, rashes, and feeling weak.

Read more
Written By Dr. Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
OffersOffers & Discounts

Get Free delivery (₹99) with circle icon

Join Circle
coupon
Get Extra 18% Off with Coupons
coupon
Extra 10% Off with Bank Offers
bank offer
bank offer
bank offer

More about the Product

Composition :

RALTEGRAVIR-400MG

Manufacturer/Marketer :

Msd Pharmaceutical Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

NPPA :

Regulated

About Isentress 400mg Tablet

Isentress 400mg Tablet is an antiviral medicine used to treat Human Immunodeficiency Virus (HIV-1) infection in both adults and children. It is prescribed as part of a combination therapy with other antiretroviral medications to help control the virus. By lowering the amount of HIV in your body, this medicine helps your immune system stay strong and work more effectively.

To achieve the best results, you must take Isentress 400mg Tablet consistently every single day at the exact times recommended by your doctor. You can take this oral tablet with or without food, making it easy to incorporate into your daily routine. Adopting a nutrient-rich diet, exercising regularly, and getting enough rest can also support your overall immune health while taking this treatment.

While taking Isentress 400mg Tablet , some people may experience common, mild side effects such as headaches, trouble sleeping, or nausea. However, it is vital to contact your healthcare provider immediately if you experience severe symptoms like unexplained muscle pain, a persistent skin rash, or signs of liver damage.

Before starting your treatment, tell your doctor if you have a history of liver disease, hepatitis, or any muscle conditions. Do not take this medicine if you have had a severe allergic reaction to any of its active or inactive ingredients in the past.

Some medications, like certain antacids containing aluminium or magnesium, can interfere with how your body absorbs Isentress 400mg Tablet and make it less effective. If you are pregnant, planning to become pregnant, breastfeeding, or are an older adult, consult your doctor or pharmacist to ensure this medicine is safe for you.

Uses of Isentress 400mg Tablet

Isentress 400mg Tablet is used in the treatment of HIV infection. The detailed uses of Isentress 400mg Tablet are as follows:

  • HIV-1 Infection: Isentress 400mg Tablet helps by stopping the virus from multiplying in your body, which lowers your viral load and helps your immune cells recover.
  • Post-Exposure Prevention (PEP): Doctors may prescribe Isentress 400mg Tablet in combination with other antiretroviral medicines to help prevent HIV infection after a possible exposure.

Key Benefits

Isentress 400mg Tablet helps control HIV by reducing the amount of virus in the body, allowing the immune system to function more effectively.

Benefits may include:

  • By reducing the amount of HIV in your body, Isentress 400mg Tablet helps protect and maintain CD4 (helper T) cells, which play an important role in defending your body against infections.
  • When taken consistently as part of combination antiretroviral therapy, it helps keep HIV under control and reduces the risk of disease progression.
  • The ability to take this tablet with or without food makes it easier to stay on track with your daily treatment plan, giving you more freedom in your everyday schedule.
  • When taken consistently as prescribed as part of combination antiretroviral therapy, it helps support long-term health and improves the effectiveness of HIV treatment.
Side effects of Isentress 400mg Tab 60s
  • Break down of muscles tissue leads to muscle weakness and it can be managed by eating often.
  • Observe your movements and understand why the muscle is weakening and breaking down.
  • Regularly do strengthening exercises to improve blood flow throughout the body and reduce weakness.
  • Sleep well and give enough rest to your body.
  • Take a balanced diet, quit smoking and intake of alcohol.
  • Practice yoga and meditation to improve inner strength and stay healthy.

Directions for Use

  • Isentress 400mg Tablet can be taken with or without food.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Chew the medicine completely before swallowing.
  • Do not crush or break the medicine.

How Isentress 400mg Tablet Works

Isentress 400mg Tablet belongs to a class of medicines known as integrase inhibitors. To replicate and spread, the HIV virus must insert its own genetic material into the DNA of your healthy immune cells. It relies on a specific protein called integrase to complete this insertion process. This medicine works by binding to and blocking this integrase protein. Without the help of this protein, the virus is unable to merge its genetic code with your cells, which stops it from making new copies of itself. This process helps lower the amount of virus in your blood and protects your immune cells from damage.
bannner image

Alcohol

Unsafe

It is not recommended to use alcohol with Isentress 400mg Tablet . Please consult your doctor if you have any concerns.

bannner image

Pregnancy

Consult your doctor

Limited information available for use of Isentress 400mg Tablet in pregnant women. Please consult your doctor regarding the risks and benefits for use of Isentress 400mg Tablet .

bannner image

Breast Feeding

Consult your doctor

Limited information available for use of Isentress 400mg Tablet in breastfeeding mothers. Please consult your doctor regarding the risks and benefits for use of Isentress 400mg Tablet .

bannner image

Driving

Unsafe

Isentress 400mg Tablet may cause tiredness and dizziness, which may affect your ability to drive. Do not drive if you experience any side effects after using Isentress 400mg Tablet .

bannner image

Liver

Caution

Exercise caution before using Isentress 400mg Tablet in case of liver disease as it can derange liver enzymes. Please consult your doctor to address any concerns.

bannner image

Kidney

Caution

Exercise caution before using Isentress 400mg Tablet in case of kidney disease. Please consult your doctor to address any concerns.

bannner image

Children

Caution

Isentress 400mg Tablet is not recommended for use in children below two years as the safety and effectiveness have not been established. In children above 2 years of age, the paediatrician will decide the dose based on the severity of the condition and the body weight.

bannner image

Heart

Caution

Exercise caution before using Isentress 400mg Tablet in case of heart problems. Please consult your doctor if you have any concerns.

bannner image

Geriatrics

Consult your doctor

Please consult a doctor if you have any concerns regarding the use of Isentress 400mg Tablet in elderly patients.

What if I have taken an overdose of Isentress 400mg Tablet

If you accidentally take too much of this medicine, seek immediate medical attention or contact your local poison control centre right away.

Diet & Lifestyle Advise

  • Avoid magnesium and aluminium antacids: Do not take antacids containing aluminium or magnesium close to your dose of Isentress 400mg Tablet , as they can bind with the medicine in your stomach and reduce its absorption. If you require antacids, ask your doctor or pharmacist for a safe alternative.
  • Eat a balanced, nutrient-dense diet: Focus on whole foods, lean proteins, fruits, and vegetables to keep your immune system strong and help your body manage the treatment.
  • Stay consistent with medical checkups: Attend all your scheduled blood tests and doctor appointments so your healthcare team can monitor your viral load and liver health.
  • Practice safe sex: Continue to use barrier methods such as condoms during sexual activity to protect your partners, even though consistent use of your medication lowers the risk of transmission.
health query

Have a query?

How Soon It Starts Working

The time required for Isentress 400mg Tablet to start to work: The time required for Isentress 400mg Tablet to show its action is clinically not established. The time for which the effects of Isentress 400mg Tablet last: The duration of action for Isentress 400mg Tablet is clinically unknown.

What if you forget to take Isentress 400mg Tablet

If you miss a dose, take it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and resume your regular schedule. Do not take two doses at the same time to make up for a missed one.

Storage

• Store Isentress 400mg Tablet tablets at room temperature, specifically between 68°F to 77°F (20°C to 25°C).

Drug Warnings

  • Inform your healthcare team: Tell all of your healthcare providers, including your dentist and any surgeons, that you are taking Isentress 400mg Tablet before receiving any treatment.
  • Monitor for new symptoms: Watch closely for signs of new infections, such as fever, chills, or swollen lymph nodes, as your recovering immune system may begin responding to previously hidden infections. Report these symptoms to your doctor promptly.
  • Do not share your medicine: Never share your medicine with anyone else, even if they have the same medical condition.
  • Keep an updated medicine list: Keep an up-to-date list of all prescription medicines, over-the-counter drugs, vitamins, and herbal supplements you take, and share it with your doctor at every visit.
  • Check before starting new medicines: Some medicines, including antacids containing aluminium or magnesium, can reduce how well Isentress 400mg Tablet works. Always check with your doctor or pharmacist before starting any new prescription, over-the-counter medicine, or supplement.

Drug-Drug Interactions

verifiedApollotooltip
  • Antacids (e.g., aluminium, magnesium): May significantly decrease the amount of Isentress 400mg Tablet your body absorbs, making the antiviral treatment less effective.
  • Antibiotic (e.g., rifampin): This antibiotic can speed up how your body processes Isentress 400mg Tablet , lowering its levels in your blood and reducing its ability to fight the virus.
RaltegravirMagnesium hydroxide
Severe

Drug-Drug Interactions

Login/Sign Up

How does the drug interact with Isentress 400mg Tab 60s:
Co-administration of Calcium carbonate may interfere with the absorption of Isentress 400mg Tab 60s and reduce its effectiveness.

How to manage the interaction:
Taking Calcium carbonate with Isentress 400mg Tab 60s should be avoided. Consult the doctor if you have any concerns, the doctor may recommend alternatives that do not interact with Isentress 400mg Tab 60s. Do not discontinue the medication without consulting a doctor.
RaltegravirMagnesium hydroxide
Severe
How does the drug interact with Isentress 400mg Tab 60s:
Taking magnesium hydroxide with Isentress 400mg Tab 60s may make the Isentress 400mg Tab 60s less effective.

How to manage the interaction:
Taking Magnesium hydroxide with Isentress 400mg Tab 60s together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult your doctor if you experience any unusual symtopms. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
  • No clinically significant food interactions are known with Isentress 400mg Tablet when used as directed.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

Login/Sign Up

Habit Forming

No

Therapeutic Class

[ANTIRETROVIRAL AGENTS]

FAQs

Isentress 400mg Tablet belongs to the group of medicines called antiretroviral agents used to treat HIV infection.
Isentress 400mg Tablet works by inhibiting the replication of viral DNA and by preventing it from being integrated in the human body.
No. Do not stop taking Isentress 400mg Tablet without talking to your healthcare provider, even if your viral load becomes undetectable. An undetectable viral load does not mean HIV has been cured. Stopping treatment can allow the virus to multiply again and may affect your treatment. Continue taking Isentress 400mg Tablet exactly as prescribed and speak with your doctor before making any changes.
No, Isentress 400mg Tablet is not a protease inhibitor. It is a human immunodeficiency virus integrase strand transfer inhibitor (HIV-1 INSTI), which works by blocking the virus from integrating into the DNA of new cells. In contrast, protease inhibitors are a different class of drugs that target the protease enzyme and prevent the virus from maturing correctly, making them non-infectious.
Isentress 400mg Tablet may cause side effects in some individuals. Commonly reported side effects include nausea, tiredness, insomnia, headache, and dizziness. These side effects are usually mild and temporary, often subsiding as your body adjusts to the medication. However, if you experience persistent, severe, or worsening side effects, please consult your doctor promptly for proper evaluation and guidance.
Yes, you can take Isentress 400mg Tablet with or without food. Taking it with a meal is completely safe and may help if you have a sensitive stomach. Talk to your doctor or pharmacist if you have questions about how to take your medication.
No, Isentress 400mg Tablet does not cure HIV, but it helps manage the virus so your immune system can stay strong and fight off other infections. This allows you to live a healthier and longer life. Talk to your doctor for more information on managing your health.
Take the missed dose as soon as you remember, unless it is almost time for your next dose. If your next dose is close, skip the missed one and continue your normal schedule; never double your dose. Talk to your doctor or pharmacist if you miss multiple doses.
You should avoid taking antacids that contain aluminium or magnesium at the same time as Isentress 400mg Tablet , as they can stop the medicine from working correctly. Talk to your doctor or pharmacist about safe alternatives for treating acid reflux.
There is no direct interaction between alcohol and Isentress 400mg Tablet , but heavy alcohol use can put extra stress on your liver. Since your liver processes this medication, it is best to limit your alcohol consumption. Talk to your doctor about what is safe for you.
If you are pregnant, planning to become pregnant, or breastfeeding, your healthcare provider will decide whether Isentress 400mg Tablet is the right treatment for you. Continuing effective HIV treatment during pregnancy is important because keeping your viral load low helps protect your health and reduces the risk of passing HIV to your baby. Treatment decisions should always be made together with a healthcare professional who has experience managing HIV during pregnancy. Do not stop or change your HIV medicines without medical advice.
Yes, in rare cases, Isentress 400mg Tablet can cause muscle weakness, pain, or tenderness. If you experience unexpected muscle issues without an obvious cause, seek medical care right away. Talk to your doctor if you experience these symptoms.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Plot No. -810, Sector - 3 , Industrial Area , Pthampur Dist. Dhar - 454 775 (M.P.) India
Other Info - ISE0003
whatsapp Floating Button
Buy Now
Add to Cart