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compositionComposition:IFOSFAMIDE-1000MG+MESNA-200MG
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Prescription Medicine
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₹356 with coupons & bank offers*

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Ipoget 1 gm Injection is used in the treatment of different kinds of cancer, such as blood cancer, breast cancer, non-small cell lung cancer, ovarian cancer, testicular cancer, and pancreatic cancer. Sometimes, you may experience specific side effects such as nausea, diarrhoea, vomiting, loss of appetite, headache, dizziness, hair loss, abdominal pain, pain or redness at the injection site, fever, sore throat, and cough. Before receiving this medicine, you should inform your doctor if you are allergic to any of its ingredients or if you are pregnant or breastfeeding, and about all the medications you are taking and any pre-existing medical conditions to rule out the potential side effects.

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Written By ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

IFOSFAMIDE-1000MG+MESNA-200MG

Manufacturer/Marketer :

GLS Pharma Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Ipoget 1 gm Injection

Ipoget 1 gm Injection is a parenteral prescription medicine used to treat specific types of advanced cancers, such as certain soft tissue cancers and testicular cancer. It is a combination treatment designed both to target cancer cells and to protect your bladder from treatment-related irritation. Because it is highly specialised, it is always given under the supervision of an oncologist.

Since this medication is given as an injection, healthcare professionals will inject it in a clinical setting according to a strictly timed schedule. Staying well-hydrated and maintaining a balanced diet during your treatment cycle are essential lifestyle adjustments that help support your body and protect your kidneys. Your medical team will monitor your progress closely with regular blood and urine tests.

While receiving this treatment, you may experience common side effects like nausea, hair loss, or temporary fatigue. However, you must contact your doctor immediately if you experience serious symptoms such as blood in your urine, severe fever, or unusual bruising. Your healthcare team can provide supportive therapies to help manage these issues.

Do not take this if you have severe bladder inflammation, active urinary tract infections, or severe kidney damage. Before starting therapy, tell your doctor if you have a history of radiation therapy, liver damage, or low blood cell counts. Your medical team will evaluate these conditions to ensure the treatment is safe for you.

This medicine can interact with blood thinners and certain vaccines, which may increase your risk of bleeding or infections. Pregnant or breastfeeding women must not receive this medicine due to serious risks to the baby. Elderly individuals may require closer monitoring, particularly for kidney function and blood counts, to ensure safe use.

Uses of Ipoget 1 gm Injection

 Ipoget 1 gm Injection is used to treat certain advanced cancers and help protect the bladder during chemotherapy. The detailed uses of  Ipoget 1 gm Injection are as follows:

  • Testicular cancer:  Ipoget 1 gm Injection is used to treat advanced testicular cancer, helping to shrink tumours and prevent the spread of cancer cells when other treatments have not worked.
  • Soft tissue sarcomas: It is used in combination chemotherapy regimens to target and treat cancers that develop in muscles, fat, and other supportive tissues.
  • Bladder protection during chemotherapy: It contains a protective agent that shields the bladder lining from toxic byproducts, preventing severe irritation and bleeding.

Key Benefits

Ipoget 1 gm Injection provides important benefits by combining cancer treatment with protection against treatment-related bladder complications. The key benefits of Ipoget 1 gm Injection are as follows:

  • Cancer Treatment: Ipoget 1 gm Injection offers a dual-benefit approach to cancer therapy by combining a cancer-fighting agent with a dedicated protective agent in one treatment plan. The primary benefit is its ability to disrupt the growth of cancer cells, helping to reduce tumour size and manage advanced stages of disease effectively.
  • Bladder Protection: Additionally, this combination provides crucial real-world relief by significantly lowering the risk of severe bladder irritation and bleeding, which is a common and painful complication of this specific type of chemotherapy. By protecting your urinary system, the medication allows you to complete your prescribed treatment plan with fewer interruptions and greater comfort.
Side effects of Ipoget 1 gm Injection
  • Eat protein-rich foods like fish, poultry, eggs, and legumes.
  • Include foods with minerals and vitamins essential for hair health.
  • Join a support group to connect with others experiencing hair loss.
  • Openly discuss your feelings about hair loss.
  • Consider covering up with wigs, hats, or scarves.
  • Be patient and avoid seeking miracle cures.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Boost your immunity by including immune rich foods in your diet and always remember to stay hydrated.
  • Get sufficient sleep and manage stress which helps in improving white blood cell count.
  • Consult your doctor for an effective treatment to improve the blood cell count and get regular body check up to monitor changes in the count.
  • Try to prevent the factors that cause a decrease in the white blood cells that may lead to impaired immunity.
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
  • Staying hydrated helps prevent hematuria by increasing urine production. You should drink about eight glasses of fluid per day, and more in hot weather.
  • Avoiding smoking as it is linked to urinary tract cancers.
  • Eat berries like Cranberries, blueberries, and raspberries can help promote urinary tract health and protect against infection.
  • Taking Vitamin C can help treat urinary tract infections.
  • Avoid irritants that can contribute to hematuria.
  • Empty the bladder regularly, as it can helps in preventing hematuria.
  • Wash your hands regularly with soap and water or use a hand sanitizer to prevent the spread of infections.
  • Wear masks, gloves and other protective clothing.
  • Cover sneezes and coughs with a medical mask or tissue or your elbow.
  • Take vaccinations to enhance your immunity to specific diseases.
  • Clean your utensils, linen and surfaces regularly.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Ipoget 1 gm Injection will be administered by the doctor or healthcare professional.
  • Do not self-administer.

How Ipoget 1 gm Injection Works

Ipoget 1 gm Injection contains IFOSFAMIDE and MESNA. These two components work together to treat cancer while helping protect the urinary tract from treatment-related damage. Ifosfamide works as an anticancer agent that targets the genetic material (DNA) inside rapidly multiplying cancer cells. By damaging this DNA, it stops the cancer cells from dividing and growing, which ultimately leads to their destruction. Mesna acts as a protective shield for your urinary tract. When the anticancer agent is broken down by your body, it produces a harmful byproduct that accumulates in the bladder and can cause severe irritation and bleeding. MESNA binds to this harmful byproduct in the urine, neutralising it before it can damage your bladder lining.
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Alcohol

Unsafe

Avoid alcohol consumption while treatment with Ipoget 1 gm Injection as it may cause unpleasant side effects.

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Pregnancy

Unsafe

Ipoget 1 gm Injection is not recommended to be used in pregnancy as it may cause serious side effects. Use effective birth control measures during treatment with Ipoget 1 gm Injection and for 6 months after completing the treatment. Inform your doctor If you get pregnant while you are receiving Ipoget 1 gm Injection .

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Breast Feeding

Unsafe

Ipoget 1 gm Injection is excreted in breast milk. Ifosfamide has been demonstrated to produce significant adverse effects and tumours in animal tests. It is essential to consider the importance of the medicine to the mother before discontinuing nursing. Ifosfamide should not be taken by women who are breastfeeding.

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Driving

Caution

Some patients may experience blurred vision or dizziness after using this $ name. If you experience any of these symptoms during treatment, do not drive a vehicle or operate heavy machinery.

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Liver

Caution

There were no official investigations undertaken on patients with liver impairment. Ipoget 1 gm Injection is metabolized extensively in the liver, producing both beneficial and harmful metabolites. It should be administered with caution to patients with poor liver function.

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Kidney

Caution

There were no official studies undertaken on people with kidney impairment. The kidneys eliminate Ipoget 1 gm Injection and metabolites but may accumulate in plasma with impaired renal function. Patients with renal impairment should be continuously watched for toxicity, and dose reduction may be necessary.

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Children

Caution

Ipoget 1 gm Injection is not recommended for use in children under 12 years of age as its safety and efficacy have not been established.

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Heart

Caution

Please inform your doctor if you have heart problems before receiving Ipoget 1 gm Injection , as there is limited information available on its safety in such cases.

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Geriatrics

Caution

Please inform your doctor if you are geriatric before receiving Ipoget 1 gm Injection , as there is limited information available on its safety in this age group.

What if I have taken an overdose of Ipoget 1 gm Injection

Because medical staff administer this treatment under close supervision, an overdose is highly improbable. However, if you suspect an error or experience severe sudden symptoms during or after your infusion, notify your healthcare provider or seek immediate emergency medical attention.

Diet & Lifestyle Advise

  • Stay highly hydrated: Drink at least 2 to 3 litres of water daily, especially on treatment days, to flush your bladder and help prevent irritation.
  • Eat small, frequent meals: If you experience nausea, eating smaller portions throughout the day can help maintain your strength and nutrition.
  • Avoid bladder irritants: Limit your intake of caffeine, alcohol, and spicy foods, as these can irritate your bladder and worsen urinary side effects.
  • Practise good hygiene: Wash your hands frequently and avoid close contact with people who are sick, as your immune system may be temporarily weakened.
  • Empty your bladder often: Do not hold your urine; empty your bladder regularly, including waking up during the night if necessary, to keep the medication from sitting in your bladder.
health query

Have a query?

How Soon It Starts Working

The time required for Ipoget 1 gm Injection to start to work: The onset of time for Ipoget 1 gm Injection is clinically unknown. The time for which the effects of Ipoget 1 gm Injection last: The duration of Ipoget 1 gm Injection effect is clinically unknown.

What if you forget to take Ipoget 1 gm Injection

Since this medication is given in a clinical setting by healthcare professionals, missing a dose is unlikely. If you miss an appointment for your infusion, contact your clinic immediately to reschedule and keep your treatment plan on track.

Storage

• Store the medicine according to the storage instructions on the product label,below 25°C (77°F), away from direct light and moisture.
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Keep Refrigerated. Do not freeze.

Drug Warnings

  • Inspect the solution: If you are monitoring your infusion, ensure the fluid in the bag is clear and free of particles before it is administered.
  • Report infusion site pain: Tell your nurse immediately if you feel burning, stinging, or pain around the injection site, as this could indicate the medicine is leaking into surrounding tissues.
  • Monitor your urine colour: Check your urine regularly and report any pink or red discolouration to your doctor right away.
  • Avoid live vaccines: Do not receive any live vaccines during your treatment, as your body's ability to fight off the vaccine strain is reduced.
  • Use effective contraception: Both men and women should use reliable birth control during treatment and for several months afterwards to prevent pregnancy.

Drug-Drug Interactions

verifiedApollotooltip
  • Blood thinners: May increase your risk of bleeding when taken alongside  Ipoget 1 gm Injection .
  • Other chemotherapy drugs: Can increase the risk of bone marrow suppression and kidney strain.
  • Live vaccines: May cause severe infections due to a weakened immune system.
IfosfamideCidofovir
Critical
IfosfamideTenofovir alafenamide
Severe

Drug-Drug Interactions

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IfosfamideCidofovir
Critical
How does the drug interact with Ipoget 1 gm Injection :
Taking cidofovir with Ipoget 1 gm Injection can increase the risk of kidney problems.

How to manage the interaction:
Taking Ipoget 1 gm Injection with Cidofovir together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
IfosfamideTenofovir alafenamide
Severe
How does the drug interact with Ipoget 1 gm Injection :
The combined use of Ipoget 1 gm Injection and Tenofovir alafenamide can increase the risk of kidney problems.

How to manage the interaction:
Taking Ipoget 1 gm Injection and Tenofovir alafenamide together can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
IfosfamideBupivacaine
Severe
How does the drug interact with Ipoget 1 gm Injection :
Taking Bupivacaine and Ipoget 1 gm Injection may cause methemoglobinemia, (a condition in which the iron in the hemoglobin molecule -the red blood pigment is defective, making it unable to carry oxygen effectively to the tissues).

How to manage the interaction:
Although taking bupivacaine and Ipoget 1 gm Injection together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience symptoms such as gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
IfosfamideThalidomide
Severe
How does the drug interact with Ipoget 1 gm Injection :
Taking thalidomide together with Ipoget 1 gm Injection may increase the risk of blood clots and other complications.

How to manage the interaction:
Although taking thalidomide and Ipoget 1 gm Injection together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.
IfosfamideEtanercept
Severe
How does the drug interact with Ipoget 1 gm Injection :
When Etanercept is used with Ipoget 1 gm Injection , the likelihood or severity of infection may increase.

How to manage the interaction:
Although taking Etanercept and Ipoget 1 gm Injection together can cause an interaction, it can be taken if a doctor has suggested it. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
IfosfamideLidocaine
Severe
How does the drug interact with Ipoget 1 gm Injection :
Coadministration of Ipoget 1 gm Injection with Lidocaine can increase the risk of methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
There may be a possibility of interaction between Ipoget 1 gm Injection and Lidocaine, but it can be taken if prescribed by a doctor. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
IfosfamideTofacitinib
Severe
How does the drug interact with Ipoget 1 gm Injection :
Taking Ipoget 1 gm Injection with Tofacitinib may increase the risk of serious infection.

How to manage the interaction:
Taking Tofacitinib with Ipoget 1 gm Injection together can possibly result in an interaction, but it can be taken if your doctor has advised it. It is important to keep a close eye on your condition. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
IfosfamideCladribine
Severe
How does the drug interact with Ipoget 1 gm Injection :
Combining Cladribine with Ipoget 1 gm Injection can increase the risk of developing serious infections.

How to manage the interaction:
There may be a possibility of interaction between Ipoget 1 gm Injection and Cladribine, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
IfosfamideBaricitinib
Severe
How does the drug interact with Ipoget 1 gm Injection :
Coadministration of baricitinib and Ipoget 1 gm Injection can raise the risk of developing serious infections.

How to manage the interaction:
Although there is an interaction, baricitinib can be taken with Ipoget 1 gm Injection if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not discontinue any medication without consulting a doctor.
IfosfamideClozapine
Severe
How does the drug interact with Ipoget 1 gm Injection :
Co-administration of Ipoget 1 gm Injection with Clozapine can increase the risk of neutropenia (low levels of neutrophils in blood).

How to manage the interaction:
Taking Ipoget 1 gm Injection with Clozapine together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any signs of infection like fever, chills, or a sore throat, or experience discomfort while urinating, it's best to contact a doctor right away. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
  • No clinically significant food interactions are known with Ipoget 1 gm Injection when used as directed.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTINEOPLASTIC]

FAQs

Ipoget 1 gm Injection belongs to the group of medications called antineoplastic agents. It is used to treat blood cancer, breast cancer, non-small cell lung cancer, ovarian cancer, testicular cancer and pancreatic cancer.
Ipoget 1 gm Injection is an antineoplastic agent. It works by damaging the DNA of cancer cells, preventing their growth and spread. Mesna is used along with ifosfamide to protect the bladder from toxic side effects, particularly haemorrhagic cystitis.
Ipoget 1 gm Injection may cause diarrhoea as a common side effect. If you experience this symptom, drink plenty of fluids to stay hydrated, eat non-spicy food, get plenty of rest, and take probiotics. Do not take anti-diarrheal medicines on your own without a doctor’s advice.
Ipoget 1 gm Injection may cause nausea, diarrhoea, vomiting, loss of appetite, headache, dizziness, hair loss, abdominal pain, pain or redness at the injection site, fever, sore throat, and cough. Hair loss may be temporary, and hair usually begins to grow back after treatment is completed. Most side effects improve gradually, but contact your doctor if they are severe, persistent, or concerning.
Drinking plenty of fluids helps flush your bladder and prevents the buildup of harmful byproducts that can cause bleeding and bladder irritation. Talk to your doctor about your daily hydration goals.
No, this medication can cause serious harm to an unborn baby. It is important to use highly effective birth control during treatment. Talk to your doctor if you are pregnant or planning a pregnancy.
This medication is given as an injection or slow infusion directly into a vein by a trained healthcare professional in a clinic or hospital setting. Talk to your doctor if you have questions about your infusion schedule.
You must contact your medical team immediately if you see blood or a pink tint in your urine, or if you feel pain when urinating. This requires urgent medical evaluation. Talk to your doctor right away.
You should avoid live vaccines during your treatment as they can cause serious infections due to your lowered immune system. Always talk to your doctor before scheduling any vaccinations.
In some cases, this medication can cause temporary changes in liver function tests or lead to liver damage. Your doctor will monitor your blood work regularly during treatment. Talk to your doctor if you experience yellowing of your skin or eyes.
Some patients experience fatigue, dizziness, or nausea after their infusion, which can affect their ability to drive safely. It is best to have someone else drive you home after your appointment. Talk to your doctor about how this medicine might affect you.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Drugs.com Clinical Review Team. Mesna Oral Injection Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  2. MedlinePlus. A695034 Patient Information Monograph. Bethesda, MD: U.S. National Library of Medicine (NLM); 2025. [Accessed on 02 Jun. 2026]Check here
  3. U.S. Food and Drug Administration (FDA). 019763S017Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026]Check here
  4. MedlinePlus. A695023 Patient Information Monograph. Bethesda, MD: U.S. National Library of Medicine (NLM); 2025. [Accessed on 02 Jun. 2026]Check here
  5. Electronic Medicines Compendium (EMC). Pil.1834 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  6. Electronic Medicines Compendium (EMC). Product Summary of Product Characteristics (SmPC). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  7. Drugs.com Clinical Review Team. Ifosfamide Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here

Country of origin

India

Manufacturer/Marketer address

R-4, Khirki Main Road, Malviya Nagar New Delhi- 110 017, (India)
Other Info - IPO0012
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