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compositionComposition:CANAGLIFLOZIN-100MG
prescription
Prescription Medicine
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Invokana 100 mg Tablet is used to treat type 2 diabetes in people whose sugar levels are too high and cannot be controlled by diet and exercise alone. It contains Canagliflozin, which works by inhibiting the reabsorption of glucose in the body, resulting in an increase in glucose excretion through urine. The removal of excessive glucose helps to lower the blood sugar level. Additionally, it also lowers high blood pressure due to increased diuretic effect (water loss) and reduced body weight due to a reduction in glucose availability. In some cases, you may experience urinary tract infections, changes in urination (urinating more frequently or in larger amounts, urgent need to urinate, need to urinate at night), constipation, feeling thirsty, nausea, dizziness, and nausea. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Composition :

CANAGLIFLOZIN-100MG

Manufacturer/Marketer :

Johnson & Johnson Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Invokana 100 mg Tablet

Invokana 100 mg Tablet is an oral prescription medication used to lower blood sugar levels in adults with type 2 diabetes. As a treatment that helps manage glucose levels, its primary medical purpose is to prevent serious complications associated with diabetes. It is also prescribed to reduce the risk of major cardiovascular events like heart attacks and to protect kidney health in certain individuals.

To achieve the best results, you should take Invokana 100 mg Tablet consistently once daily, preferably before your first meal of the day. It is taken orally and can be taken with or without food, but taking it before breakfast is highly recommended to manage blood sugar spikes after eating. To maximise its effectiveness, you should combine this treatment with a balanced diet, reduced sugar intake, and a regular exercise routine.

While using Invokana 100 mg Tablet , you may experience common side effects like increased urination, mild thirst, or genital yeast infections. While these are usually manageable, you must consult your doctor immediately if you face serious side effects such as severe stomach pain, persistent vomiting, or extreme dizziness, which can point to a serious metabolic issue.

Talk to your doctor before starting this medicine if you have a history of kidney disease, liver damage, low blood pressure, or a history of leg or foot amputations. Do not take this if you have type 1 diabetes, severe kidney failure, are on dialysis, or have had a severe allergic reaction to this medication in the past.

This medication can interact with other drugs like insulin, water pills, or blood pressure medicines, which may increase your risk of low blood sugar or dehydration. It is also important to limit alcohol intake and avoid smoking to protect your cardiovascular and metabolic health while on this treatment. If you are pregnant, breastfeeding, or are an older adult, you should consult your healthcare provider before taking this medicine.

Uses of Invokana 100 mg Tablet

Invokana 100 mg Tablet is used to treat type 2 diabetes mellitus and reduce cardiovascular risk. The detailed uses of Invokana 100 mg Tablet are as follows:

  • Type 2 diabetes mellitus: Invokana 100 mg Tablet helps lower blood sugar levels in adults by helping the kidneys remove excess sugar through urine.
  • Heart disease risk reduction: It helps decrease the risk of major cardiovascular events, such as heart attacks, strokes, or death, in adults who have both type 2 diabetes and established heart conditions.
  • Diabetic kidney disease: It helps slow the progression of kidney damage and reduces the risk of hospitalisation for heart failure in adults with type 2 diabetes.

Key Benefits

Invokana 100 mg Tablet helps manage blood sugar levels while providing additional protection for the heart and kidneys. By improving glucose control and supporting the health of vital organs, it contributes to better overall wellbeing and may help reduce the risk of long-term diabetes-related complications.

  • Helps Control Blood Sugar Levels: By reducing rises in blood sugar after meals, Invokana 100 mg Tablet helps maintain more stable glucose levels throughout the day. This supports effective diabetes management and may help lower the risk of complications associated with uncontrolled blood sugar.
  • Supports Heart Health: Invokana 100 mg Tablet helps reduce the risk of hospitalisation due to heart failure and supports better cardiovascular health. This may contribute to improved stamina, reduced shortness of breath, and greater comfort during everyday activities.
  • Helps Protect Kidney Function: In addition to managing blood sugar, Invokana 100 mg Tablet supports kidney health and may help slow the progression of diabetes-related kidney damage, promoting better long-term kidney function and overall health outcomes.
Side effects of Invokana 100 mg Tablet
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Drink six to eight glasses of water per day to be healthy.
  • Healthy urinary habits can help minimize pollakiuria (frequent urinating).
  • Avoid liquids containing caffeine, artificial sweeteners, and soda, as they might cause bladder discomfort.
  • Add bladder-friendly foods such as omega-3 fatty acids, blueberries, and cranberries.
Managing Medication-Triggered UTIs: A Comprehensive Approach:
  • Inform your doctor about the medication you're taking and the UTI symptoms you're experiencing.
  • Your doctor may adjust your medication regimen or consider alternative medications or dosages that may reduce the risk of UTIs.
  • Drink plenty of water (at least 8-10 glasses a day) to help flush out bacteria. Avoid sugary drinks and caffeine, which can exacerbate UTI symptoms.
  • Urinate when you feel the need rather than holding it in. This can help prevent bacterial growth and reduce the risk of UTIs.
  • Consider cranberry supplements: Cranberry supplements may help prevent UTIs by preventing bacterial adhesion.
  • Monitor UTI symptoms and report any changes to your doctor.
  • If antibiotics are prescribed, take them as directed and complete the full course.
  • High sugar intake can promote yeast growth, which is a common cause of balanoposthitis. Reduce consumption of sugary drinks, processed foods, and excessive sweets.
  • A well-balanced diet rich in fruits, vegetables, whole grains, and lean protein supports overall health and immune function, which can help prevent infections.
  • Staying well-hydrated is important for overall health and may help prevent balanoposthitis by keeping the urinary tract healthy.
  • Take warm water sitz baths, use saline baths, and use over-the-counter talcum powders.
  • Thoroughly dry the area after washing.
  • Avoid harsh soaps, detergents, and scented products in the genital area.
  • Use topical antifungal agents like bacitracin.
  • Eat a balanced diet rich in fruits, vegetables, and whole grains to support overall health.
  • Incorporate probiotic-rich foods like yogurt or kefir into your diet to promote gut health.
  • Practice good genital hygiene by washing with warm water and avoiding harsh soaps.
  • Wear loose, breathable cotton underwear to reduce moisture buildup.
  • Avoid douching and scented soaps that can disrupt natural vaginal balance.
  • Stay dry and change out of wet clothes promptly to prevent yeast growth.
  • Limit excessive sugar consumption to reduce yeast growth.
  • Consider adding antifungal foods like garlic or turmeric to your diet.
  • Reduce stress levels by practicing calming techniques such as mindfulness, meditation, or controlled breathing exercises.
  • Complete the full course of prescribed antifungal treatment to prevent recurrence.
  • Consult your doctor if you experience frequent or severe yeast infections.

Directions for Use

  • Invokana 100 mg Tablet can be taken with or without food, but it is best to take it before the first meal of the day.
  • It is usually taken once daily or as prescribed by your doctor.
  • Swallow Invokana 100 mg Tablet as a whole with a glass of water.
  • Do not crush, chew, or break it.

How Invokana 100 mg Tablet Works

Invokana 100 mg Tablet contains canagliflozin. This medication works in a unique way that does not rely entirely on your body's insulin. Under normal conditions, the kidneys filter glucose and then reabsorb much of it back into the bloodstream through a protein called sodium-glucose co-transporter 2 (SGLT2). Canagliflozin works by blocking SGLT2 in the kidney tubules, reducing the reabsorption of glucose. As a result, excess glucose is removed from the body through the urine, helping lower blood sugar levels independently of insulin. This unique pathway helps lower your blood sugar levels independently of insulin, providing a steady and reliable way to manage diabetes.
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Alcohol

Unsafe

You should avoid consuming alcohol with Invokana 100 mg Tablet as it may alter your blood sugar levels or lead to serious side effects.

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Pregnancy

Consult your doctor

Invokana 100 mg Tablet is not recommended during pregnancy. However, your doctor may prescribe it for you during pregnancy if he/she feels the benefit outweighs the risk. You should not take Invokana 100 mg Tablet without a doctor's advice.

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Breast Feeding

Consult your doctor

There is no sufficient data on how Invokana 100 mg Tablet affects breastfeeding. It is safe to seek medical advice before you start Invokana 100 mg Tablet if you are breastfeeding.

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Driving

Caution

Invokana 100 mg Tablet should not affect your ability to drive or operate machinery/tools.

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Liver

Caution

Invokana 100 mg Tablet to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Invokana 100 mg Tablet to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor depending on your renal functions. Invokana 100 mg Tablet is not recommended in severe kidney disease. Regular monitoring of kidney function tests is therefore important if you're taking Invokana 100 mg Tablet .

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Children

Caution

Invokana 100 mg Tablet is not recommended for children below 18 years of age, as the safety and effectiveness were not established.

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Heart

Consult your doctor

Invokana 100 mg Tablet is not contraindicated in heart patients. It is often prescribed to reduce the risk of cardiovascular death and hospitalisation for heart failure in adults with type 2 diabetes and established cardiovascular disease.

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Geriatrics

Consult your doctor

While Invokana 100 mg Tablet is safe to be taken by older patients, it is critical to exercise caution and monitor for potential adverse effects, such as dehydration, low blood pressure, and urinary tract infections, which are more common in older adults. Before starting dapagliflozin, it is recommended that you consult with a doctor, particularly if you are 75 or older.

What if I have taken an overdose of Invokana 100 mg Tablet

If you suspect an overdose or experience severe symptoms after taking too much of this medication, seek immediate medical attention or contact a poison control centre right away.

Diet & Lifestyle Advise

  • Drink plenty of water throughout the day to stay well-hydrated, as this medicine naturally increases fluid loss through urination.
  • Follow a balanced meal plan focusing on vegetables, lean proteins, and fibre-rich carbohydrates to help maintain stable blood sugar levels.
  • Engage in regular physical activity, such as walking, swimming, or cycling, as recommended by your doctor to help your body use insulin more effectively.
  • Take extra care of your feet by checking them daily for cuts, sores, or redness, and wear comfortable, protective footwear.

Health Queries

What medications and daily management strategies can help me live a long and healthy life with Type 2 diabetes?

Chandrakanta Jena

Chandrakanta Jena

Pharm D

Living a long, healthy life with Type 2 diabetes is entirely achievable. Commonly prescribed generic medications, like metformin, help your body use insulin better, while newer classes like SGLT2 inhibitors or GLP-1 receptor agonists also protect your heart and kidneys. For daily management, focus on a balanced diet rich in fibre, vegetables, and lean proteins while limiting processed sugars. Aim for 30 minutes of moderate activity, like brisk walking, most days. Monitoring your blood sugar as advised, staying hydrated, and attending regular check-ups with your healthcare team will keep you on the right track. With these habits, you can successfully manage your health.

What are the side effects of Invokana?

Y. Lakshmi Thulasi

Y. Lakshmi Thulasi

Pharm-D (Post baccalaureate)

Dehydration, genital/urinary infections, and frequent urination are all possible side effects of invokana. Low blood pressure, lightheadedness, or electrolyte imbalance could result from it. Monitoring is necessary because it might occasionally result in renal issues or ketoacidosis.
health query

Have a query?

How Soon It Starts Working

The time required for Invokana 100 mg Tablet to start to work: Invokana 100 mg Tablet ideally shows its action within 1 to 2 hoursafter administration. The time for which the effects of Invokana 100 mg Tablet last: The effect of Invokana 100 mg Tablet lasts for 24 hours.

What if you forget to take Invokana 100 mg Tablet

If you miss a dose, take it as soon as you remember on that day. If you do not remember until the next day, skip the missed dose and resume your regular daily schedule. Do not take two doses at the same time to make up for a missed one.

Storage

•Store Invokana 100 mg Tablet tablets at room temperature, safely between 20°C and 25°C (68°F to 77°F). •Keep the tablets in their original packaging to protect them from light and moisture.

Drug Warnings

  • Monitor your fluid intake carefully, especially during hot weather or physical exercise, to avoid severe dehydration.
  • Check your blood sugar levels regularly as directed by your healthcare team, especially during periods of stress, illness, or changes in your diet.
  • Pay close attention to genital hygiene to help reduce the risk of yeast or urinary tract infections.
  • Inform your surgeon or dentist that you are taking this medication well in advance of any scheduled surgeries, as you may need to pause treatment.
  • Always keep a quick source of sugar, like fruit juice or glucose tablets, nearby in case you experience sudden low blood sugar.
  • Do not take Invokana 100 mg Tablet unless specifically advised by your healthcare provider if you have type 1 diabetes, severe kidney failure or are receiving dialysis or had a serious allergic reaction to canagliflozin or any of its ingredients or are in the second or third trimester of pregnancy, unless your doctor determines otherwise
  • Canagliflozin has been associated with an increased risk of lower-limb amputations, particularly involving the toes, feet, or legs. Inform your doctor if you have a history of amputation, peripheral vascular disease, diabetic foot ulcers, or neuropathy. Seek medical attention promptly if you develop new foot pain, sores, ulcers, tenderness, infection, or changes in skin colour. 

Drug-Drug Interactions

verifiedApollotooltip

Drug-Drug Interactions

  • Diuretics (water pills): Taking these alongside Invokana 100 mg Tablet can significantly increase your risk of dehydration and low blood pressure.
  • Insulin or sulfonylureas: Combining these medications with Invokana 100 mg Tablet may lower your blood sugar too much, increasing the risk of hypoglycaemia.

Drug-Food Interactions

  • Taking this medication before your first meal of the day is recommended to help control the rise in blood sugar that occurs after eating.

Drug-Disease Interactions

  • Severe kidney disease: This medicine is not effective and should not be used if you have severe kidney failure or are on dialysis.
  • Low blood pressure (hypotension): This medication can lower blood pressure further due to increased fluid loss.
  • History of diabetic ketoacidosis: Individuals with a history of this serious condition may have an increased risk of developing it again.
CanagliflozinGatifloxacin
Critical
CanagliflozinMorphine
Severe

Drug-Drug Interactions

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CanagliflozinGatifloxacin
Critical
How does the drug interact with Invokana 100 mg Tablet:
Co-administration of Invokana 100 mg Tablet with Gatifloxacin may affect blood glucose levels. Both low blood glucose and, less frequently, high blood glucose have been reported.

How to manage the interaction:
Although there is a possible interaction, Invokana 100 mg Tablet can be taken with Gatifloxacin if prescribed by the doctor. Consult the prescriber if you experience symptoms such as nervousness, confusion, headache, dizziness, drowsiness, tremors, nausea, hunger, weakness, perspiration, palpitation, rapid heartbeat, increased urination, increased thirst, and increased hunger. Maintaining blood glucose levels is advised. Do not discontinue the medication without consulting a doctor.
CanagliflozinMorphine
Severe
How does the drug interact with Invokana 100 mg Tablet:
Co-administration of Morphine with Invokana 100 mg Tablet may increase the blood levels and side effects of morphine.

How to manage the interaction:
Co-administration of Morphine with Invokana 100 mg Tablet can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any symptoms like trouble breathing, feeling tired, or having a cough, dizziness, drowsiness, difficulty concentrating, impaired judgment, reaction speed, and motor coordination, make sure to contact a doctor immediately. Do not stop using any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTIDIABETICS]

FAQs

Invokana 100 mg Tablet is used to treat type 2 diabetes, also called 'non-insulin-dependent diabetes.
Invokana 100 mg Tablet is a type of medicine known as a sodium-glucose cotransporter-2 (SGLT2) inhibitor used for the treatment of type -2 diabetes. It lowers blood sugar levels by blocking the action of SGLT-2 in the kidney and removing excess sugar from your body through urination.
Take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and go back to your regular dosing schedule.
Do not stop taking Invokana 100 mg Tablet until your prescribed course is finished, even if you feel better.
Once blood sugar goes below the normal range (70mg/dl), it is called hypoglycemia or low blood sugar. If you feel your sugar level is going down and feel weak, immediately eat sugar candies. It will help to balance the blood sugar level in your body. So, it is advisable to keep sugar candies with you if you have diabetes.
Type 2 diabetes mellitus is a chronic (long-lasting) condition that keeps the body away from properly utilizing insulin. Hence, people affected with type 2 diabetes either do not produce enough insulin, or there is resistance to the action of insulin. Middle-aged or older are most likely to suffer from type 2 diabetes, so it is also known as adult-onset diabetes. The symptoms include frequent urination at night, increased thirst, slow wound healing, increased hunger, fatigue, and blurred vision.
During the treatment with Invokana 100 mg Tablet , maintain a healthy diet and do regular exercise to control blood sugar levels. Avoid skipping any dose of Invokana 100 mg Tablet , as it may cause fluctuations in your blood sugar levels. Tell your doctor about all of your medical conditions and any other medications that you are taking.
No, Invokana tablet and metformin are not the same. Though, both the medicines are used to treat Type 2 diabetes mellitus, their mechanisms of action are different.
Take Invokana 100 mg Tablet with or without food as prescribed by your doctor. Try to take it at the same time every day. Swallow it as whole with a glass of water. Do not crush, break or chew it.
Record your blood sugar levels, either daily or on a regular basis so that you can show them to your doctor on your next visit. Your doctor will examine these reports and let you know whether Invokana 100 mg Tablet is working or not.
Patients with a history of amputation are more prone to lower limb amputation. Patients with foot ulcers or sores, as well as those who have or had heart disease, are also at high risk. Additionally, patients who have or have suffered from neuropathy (nerve damage that causes numbness, tingling, and pain, usually in your hands and feet) and peripheral vascular disease (narrowing of blood vessels in feet, legs, or arms causing numbness, pain, or coldness) are also at high risk of lower limb amputation.
Invokana 100 mg Tablet usually causes loss of fat mass which typically results in weight loss. However, this may differ from person to person depending upon the doses and whether it is being used alone or with other diabetes medications.
The serious side effects of Invokana 100 mg Tablet are sudden kidney impairment, ketoacidosis (increased ketones in your blood or urine), low blood sugar, some allergic reaction, and serious urinary tract infections. Although it is rare, Invokana 100 mg Tablet may also cause a severe bacterial infection that may damage the tissue beneath the skin in the perineum (area between and around the anus and genitals). Invokana 100 mg Tablet may weaken your bones, increasing the risk of fractures, especially in the wrists, upper arms, or hands.
No, Invokana 100 mg Tablet is only approved to treat type 2 diabetes and should not be used by individuals with type 1 diabetes. Talk to your doctor.
It is best to avoid or limit alcohol, as it can increase your risk of dehydration and a dangerous medical condition called diabetic ketoacidosis. Talk to your doctor.
Because this medication increases sugar in your urine, genital yeast infections can occur. Mild cases can often be treated easily, but you should seek guidance on how to manage them. Talk to your doctor.
Yes, you may need to temporarily stop taking this medication several days before a scheduled surgery to lower the risk of ketoacidosis. Talk to your doctor.
This medication is generally not recommended during the second and third trimesters of pregnancy because it may affect the developing kidneys of the unborn child. Talk to your doctor.
Canagliflozin works in the kidney tubules by blocking the SGLT2 transporter, which helps remove excess glucose through the urine. Because its effectiveness depends on adequate kidney function, your doctor will check your kidney function using tests such as eGFR before starting treatment and during follow-up visits. Dose adjustments or treatment restrictions may be necessary if kidney function declines. Talk to your doctor.

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Country of origin

Italy

Manufacturer/Marketer address

Corporate Communications, Johnson & Johnson Private Limited., 501 Arena Space, Behind Majas Bus Depot, Off Jogeshwari Vikhroli Link Road, Jogeshwari (E), Mumbai 400 060
Other Info - INV0037
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