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compositionComposition:DICLOFENAC-50MG+DICYCLOMINE-20MG
prescription
Prescription Medicine
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Intopas Injection is used to treat Irritable bowel syndrome (IBS) and Dysmenorrhea (pain during menses periods). It contains Dicyclomine (antispasmodic) and Diclofenac (Non-steroidal anti-inflammatory disease/ pain killer), which relieves abdominal pain and cramps. It prevents sudden muscle contractions (spasms), thus reducing cramps, bloating, pain and discomfort.

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Written By Dr. Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

DICLOFENAC-50MG+DICYCLOMINE-20MG

Consume Type :

Parenteral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Intopas Injection

Intopas Injection is a prescription injection used to treat acute, severe abdominal cramps and spasms, such as those caused by kidney stones, gallstones, or severe gut issues. It combines two actions to relieve both the sharp muscle spasms and the underlying pain and inflammation. This medicine is typically injected when oral medicines are not suitable or fast relief is needed.

This injection is usually intended for short-term management of acute pain and spasms rather than long-term use. If pain continues beyond a few days or requires repeated injections, your doctor should reassess your condition and treatment plan. Since it is injected, it does not depend on food intake, but adopting gentle lifestyle habits like drinking plenty of water and avoiding greasy meals can help support your recovery.

Common side effects of Intopas Injection include dry mouth, sleepiness, blurred vision, and mild swelling or pain at the injection site. If you experience serious side effects like severe chest pain, shortness of breath, dark tarry stools, or sudden changes in urination, you should seek emergency medical help immediately.

Talk to your doctor before receiving Intopas Injection if you have a history of stomach ulcers, asthma, high blood pressure, or kidney disease. This medicine should generally be avoided in people with severe kidney impairment, unless your doctor determines that the benefits outweigh the risks. Do not take this if you have severe heart failure, active bleeding in your stomach, glaucoma, or an enlarged prostate that makes it hard to urinate.

This medication can interact with blood thinners, other pain relievers, and blood pressure medicines, increasing the risk of bleeding or kidney strain. If you are pregnant, breastfeeding, or elderly, please consult your doctor, as this injection requires extra caution in these groups.

Uses of Intopas Injection

This medicine is used to relieve severe pain and muscle spasms associated with conditions affecting the urinary tract, gallbladder, and digestive system. The detailed uses of this medicine are as follows:

  • Ureteric and renal colic: Intopas Injection helps relieve the intense pain and muscle spasms in the urinary tract caused by kidney stones.
  • Biliary colic: It helps reduce severe abdominal pain and spasms caused by gallstones blocking the bile ducts.
  • Severe gastrointestinal spasms: It relaxes the smooth muscles of the stomach and intestines, helping relieve painful abdominal cramps, spasms, and bloating associated with gastrointestinal disorders.

Key Benefits

Intopas Injection provides rapid relief from pain and muscle spasms, helping improve comfort during acute painful conditions. Its benefits include:

  • Helps provide rapid relief from severe pain and muscle spasms when administered by injection.
  • Relieves both inflammation and smooth muscle spasms, providing dual-action pain relief.
  • Helps reduce the intense pain associated with kidney stones, gallstones, and severe gastrointestinal spasms.
  • Improves comfort and mobility during acute painful episodes, supporting a smoother recovery.
  • Bypasses the digestive system when given by injection, allowing the medicine to act quickly in emergency or severe pain situations.

Directions for Use

  • Your doctor will determine the dosage and frequency depending on your condition.
  • Intopas Injection will be administered by a healthcare professional.
  • Do not self-administer.

How Intopas Injection Works

Intopas Injection contains Dicyclomine and Diclofenac. Dicyclomine: It relaxes the smooth muscles of the stomach, intestines, urinary tract, and bile ducts by blocking the action of acetylcholine, a natural chemical that triggers muscle contractions. This helps relieve painful spasms and cramping. Diclofenac: It is a non-steroidal anti-inflammatory drug (NSAID) that reduces pain and inflammation by blocking the production of prostaglandins, the chemical messengers responsible for pain, swelling, and inflammation.
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Alcohol

Unsafe

Consumption of alcohol should be avoided during treatment with Intopas Injection as it contains diclofenac which causes unpleasant side effects like gastric bleeding.

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Pregnancy

Caution

Intopas Injection should not be used when pregnancy unless clearly necessary. So, inform your doctor if you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Intopas Injection.

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Breast Feeding

Caution

Intopas Injection should not be used in nursing mothers unless clearly necessary. So, inform your doctor if you are a nursing mother. Your doctor will weigh the benefits and potential risks before prescribing Intopas Injection.

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Driving

Caution

Intopas Injection may cause dizziness, drowsiness and visual disturbances, affecting their ability to drive or operate machinery. Hence avoid driving or operating machinery after receiving Intopas Injection.

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Liver

Caution

Caution should be exercised during treatment with Intopas Injection if you have any history of Liver diseases/conditions. Depending on your LFT tests, your physician may make a dose adjustment.

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Kidney

Caution

Caution should be exercised during treatment with Intopas Injection if you have any history of kidney diseases/conditions. Depending on your RFT tests, your physician may make a dose adjustment.

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Children

Unsafe

Intopas Injection is not to be used in children below 12 years of age as the safety and efficacy for Intopas Injection are not established.

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Heart

Caution

Intopas Injection is not advised for heart patients due to increased cardiovascular risks. Always consult your doctor for safer alternatives and proper evaluation before use.

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Geriatrics

Caution

Geriatric patients should use Intopas Injection with caution due to increased risks of gastrointestinal, kidney, and heart side effects. Medical supervision and dose adjustments are essential for safe use.

What if I have taken an overdose of Intopas Injection

If you suspect an overdose, seek emergency medical attention immediately. Symptoms of an overdose may include severe dizziness, extreme drowsiness, shallow breathing, or severe stomach pain.

Diet & Lifestyle Advise

  • Stay well-hydrated: Drink plenty of water unless your doctor has advised otherwise. Adequate hydration may help support recovery, especially if you are being treated for kidney stone-related pain.
  • Avoid fatty and spicy foods: Limit greasy, fried, and highly spiced foods, as they may trigger gallbladder contractions and worsen biliary colic.
  • Eat small, frequent meals: Have smaller meals more often to reduce strain on your digestive system and help minimize abdominal cramps and spasms.
  • Avoid alcohol and smoking: Refrain from alcohol and smoking, as they can irritate the stomach lining and increase the risk of stomach irritation or bleeding while using Intopas Injection.
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How Soon It Starts Working

The time required for Intopas Injection to start to work: The exact onset time of Intopas Injection has not been clinically established. The time for which the effects of Intopas Injection last: The duration of Intopas Injection’s effect is clinically not established.

What if you forget to take Intopas Injection

Since this injection is typically given for acute pain in a clinical setting, missing a dose is rare. If you are on a scheduled regimen at home and miss a dose, inject it as soon as you remember. However, if it is almost time for your next dose, skip the missed one and continue your normal schedule. Do not double the dose to make up for a missed one.

Storage

• Store Intopas Injection according to the instructions provided on the product label or package insert. • Many formulations are stored at controlled room temperature (typically 20°C to 25°C [68°F to 77°F]), but storage recommendations may vary by manufacturer.

Drug Warnings

  • Inspect the injection before use: Check the vial or ampoule before administration. Do not use the medicine if the solution is cloudy, discolored, or contains visible particles.
  • Rotate injection sites: Change the injection site with each dose to help prevent muscle soreness, irritation, or tissue damage.
  • Avoid driving or operating machinery: Do not drive, operate machinery, or perform tasks requiring alertness or clear vision immediately after the injection, as it may cause drowsiness, dizziness, or temporary blurred vision.
  • Dispose of injection equipment safely: Never reuse needles or syringes. Dispose of all used injection equipment immediately in a puncture-resistant sharps disposal container.
  • Inform your healthcare providers: Tell your doctor, dentist, or surgeon that you are receiving Intopas Injection before undergoing any medical or dental procedures.

verifiedApollotooltip
  • Pain relievers, blood thinners, and steroids: Using Intopas Injection with other NSAIDs, blood thinners (such as warfarin), or oral corticosteroids may increase the risk of stomach irritation, ulcers, or bleeding.
  • Anticholinergic medicines and sedatives: This medicine may increase drowsiness, dry mouth, blurred vision, and other anticholinergic effects when used with other anticholinergic medicines, antihistamines, or muscle relaxants.
  • Blood pressure medicines: Intopas Injection may reduce the effectiveness of certain blood pressure medicines, including ACE inhibitors and diuretics.

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verifiedApollotooltip
  • Alcohol: Avoid alcohol while using this medicine, as it can significantly increase the risk of stomach irritation, ulcers, and gastrointestinal bleeding.

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[GASTROINTESTINAL AGENTS]

FAQs

Intopas Injection is used to treat Irritable bowel syndrome (IBS) and Dysmenorrhea (pain during menses periods).
Intopas Injection contains two medications: dicyclomine (antispasmodic) and diclofenac (nonsteroidal anti-inflammatory drugs), both of which reduce abdominal pain and cramps. Dicyclomine works by relaxing the stomach and intestinal muscles (intestine). It relieves cramps, bloating, pain, and discomfort by preventing abrupt muscle contractions (spasms). They efficiently alleviate pain when used together.
Because injectables are usually administered by a healthcare professional, there will be no missed or forgotten doses. However, if a dose is missed, inform your doctor on a priority basis.
Yes, the use of Intopas Injection can cause diarrhea in some cases. In the case of diarrhea, increase the intake of fluids like drinking plenty of water. If still, diarrhea persists, inform your doctor and do as advised.
Yes, the use of a Intopas Injection can cause dry mouth. If you feel excessively thirsty, increase fluid intake and avoid spicy and salty food.
Intopas Injection should be used with caution in patients with glaucoma (an eye condition that affects the optic nerve) as it may worsen the symptoms and be used only when prescribed by a doctor.
No, you should not stop taking Intopas Injection if your pain is relieved. Complete the duration of treatment advised by the doctor to treat your condition effectively.
Intopas Injection may cause kidney damage if used for a longer duration. Inform the doctor if you have a history of kidney disease or related conditions. Based on your renal function , the doctor may adjust the dosage accordingly.
No, you should not take higher than the prescribed dose of Intopas Injection as it may cause unpleasant side effects. However, as Intopas Injection will be administered by the doctor, it is unlikely for you to exceed the recommended dosage.
Intopas Injection should be stored in a cool and dry place away from sunlight. Keep it out of sight and reach of children.
The side effects of Intopas Injection include dizziness, nausea, diarrhoea, heartburn, vomiting, loss of appetite, sleepiness, dryness of the mouth, weakness, nervousness, and blurred vision. Consult the doctor if any of these symptoms persist or worsen.
Intopas Injection is generally not recommended during pregnancy, especially during the third trimester, as it may harm the unborn baby. Talk to your doctor to discuss safer alternatives.
It is highly advised to avoid alcohol while using Intopas Injection, as the combination can severely increase your risk of stomach irritation, ulcers, and bleeding. Talk to your doctor if you have concerns.
No, you should avoid driving or operating machinery immediately after receiving Intopas Injection, as it can cause dizziness, sleepiness, and blurred vision. Talk to your doctor about when it is safe to drive.
Mild pain or redness at the injection site is common and usually goes away on its own. However, if the swelling increases, becomes extremely painful, or shows signs of infection like pus, talk to your doctor immediately.
Intopas Injection is typically reserved for adults and is not recommended for children unless specifically prescribed and monitored by a pediatrician. Talk to your doctor for child-safe alternatives.
Yes, in some cases, Intopas Injection can cause fluid retention or affect blood pressure, especially in individuals with pre-existing heart or kidney conditions. Talk to your doctor to monitor your condition safely.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Dicyclomine [Prescribing Information]. 2011. [Accessed on 15 Apr. 2019]Check here
  2. Dicyclomine [Prescribing Information]. 2024. [Accessed on 01 March. 2025]Check here
  3. Tong J Gan. Diclofenac: an update on its mechanism of action and safety profile. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. July 2010. [Accessed on 21st May 2022].Check here
  4. NIH National Library of Medicine, National center for biotechnology information. Dicyclomine. Pubchem. [Accessed on 21st May 2022].Check here
  5. Teva Pharmaceuticals USA, Inc. Dicyclomine. Dailymed. [Revised in November 2020]. [Accessed on 21st May 2022].Check here
  6. Dexcel Ltd. Diclofenac Sodium. Dailymed. [Revised in June 2022]. [Accessed on 21st May 2022].Check here
  7. Dicyclomine Hcl Diclofenac Sodium Injection 6820409.Html. [Accessed on 02 Jun. 2026]Check here

Country of origin

India
Other Info - IN14123
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