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  3. Inonza 1 mg Injection 1's

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Inonza 1 mg Injection 1's, Pack of 1 INJECTION
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Written By Lakshmithulasi Yarragunta ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Inonza 1 mg Injection is used to treat Acute lymphocytic leukemia (ALL). It contains Inotuzumab Ozogamicin, which belongs to the class of monoclonal antibodies. It works by inhibiting the DNA and RNA transcription that is essential for cancer cell growth. This helps prevent the growth and further spread of cancerous or non-cancerous cells. Inonza 1 mg Injection may cause certain side effects, such as skin rash, fatigue, headache, decreased platelet count, nausea, vomiting, diarrhea, abdominal pain, dizziness, myalgia, and injection site reactions.

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Composition :

INOTUZUMAB OZOGAMICIN-1MG

Manufacturer/Marketer :

Pfizer Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Inonza 1 mg Injection

Inonza 1 mg Injection is an anti-cancer medicine used in the treatment of acute lymphoblastic leukemia, a blood cancer that primarily affects the blood and bone marrow. Inonza 1 mg Injection is used in the treatment of patients with relapsed or refractory B-cell precursor acute lymphoblastic leukemia (ALL).

Inonza 1 mg Injection contains Inotuzumab Ozogamicin, which belongs to the class of monoclonal antibodies. It works by inhibiting the DNA and RNA transcription that is essential for cancer cell growth. This helps prevent the growth and further spread of cancerous or non-cancerous cells.

Inonza 1 mg Injection may cause certain side effects, such as skin rash, fatigue, headache, decreased platelet count, nausea, vomiting, diarrhea, abdominal pain, dizziness, myalgia, and injection site reactions. These side effects do not require medical attention and gradually resolve over time. Inonza 1 mg Injection is a parenteral preparation. It will be administered by a trained oncologist. Do not self-administer.

Inonza 1 mg Injection should be avoided if you are allergic to it or any other components present in it. Before taking Inonza 1 mg Injection, caution should be exercised if you have/had liver/kidney disease, gastrointestinal disorders, or cardiac problems, as it may cause serious side effects or worsen such conditions. This medicine is known to cause embryo-fetal toxicity. Hence, inform your doctor if you are pregnant, planning to become pregnant or are breastfeeding before starting the treatment.

Uses of Inonza 1 mg Injection

Inonza 1 mg Injection is used in the treatment of Acute lymphocytic leukemia (ALL). The detailed use of Inonza 1 mg Injection is as follows:

  • Acute Lymphoblastic Leukemia: Inonza 1 mg Injection is used in the treatment of relapsed or refractory B-cell precursor Acute Lymphoblastic Leukemia (ALL) in adults. It specifically targets CD22-positive cancer cells, which are commonly found in B-cell ALL.

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Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication.
  • Inonza 1 mg Injection will be administered by a nurse or doctor.
  • Do not self-administer.

Medicinal Benefits

Inonza 1 mg Injection contains Dasatinib, which is used in the treatment of acute lymphoblastic leukemia (ALL). It works by binding the ADC (antibody-drug conjugate) and CD22 tumor cells containing N-acetyl-gamma-calicheamicin (cytotoxic agent) and forms the ADC-CD22 complex. This complex causes the activation of N-acetyl-gamma-calicheamicin and induces DNA breakage. Thus, it helps stop the abnormal growth of cancer cells and thus reduce the further spread to other parts of the body.

How Inonza 1 mg Injection Works

Inonza 1 mg Injection contains Inotuzumab Ozogamicin, which belongs to the class of monoclonal antibodies. It works by inhibiting the DNA and RNA transcription that is essential for cancer cell growth. This helps prevent the growth and further spread of cancerous or non-cancerous cells.

Storage

• Store in a cool and dry place away from sunlight.• Keep Inonza 1 mg Injection out of the sight and reach of children. • Cold chain - To be stored in cold places at 2ºC to 8ºC.
Side effects of Inonza 1 mg Injection
  • Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
  • Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
  • Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
  • Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
  • If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
  • In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
  • Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
  • If you experience severe bleeding or bruising, seek emergency medical attention immediately.
  • High levels of bilirubin in blood leads to yellow discolouration of skin and eyes which is a significant liver issue that needs immediate medical attention.
  • Eating a balanced diet can help manage such side effects and must be taken as a dietician suggests.
  • Exercise regularly to maintain a good metabolism in your body.
  • Avoid alcohol consumption as it can affect liver functioning and worsen if there is a yellow discolouration of the skin and eyes.
  • Prevent toxins from chemicals that can be touched and inhaled. Ensure to manage your medications carefully.
  • High levels of liver enzymes need immediate medical attention.
  • Watch your diet and consume low-fat foods, like green leafy vegetables, fish, whole grains, nuts, etc.
  • Regularly do strengthening exercises to control your cholesterol levels.
  • Avoid drinking alcohol as it can affect your liver.
  • Focus on losing weight as it can help control cholesterol and maintain liver enzymes.
  • Practice yoga and meditation to improve liver functioning and overall health.
  • Talk to your doctor about medicines to manage neutropenia based on the underlying cause.
  • Avoid contact with people who are sick.
  • Wash your hands regularly with soap and water.
  • Avoid unpasteurized dairy products.
  • Eat a balanced diet: Less liver, seafood, and red meat, and more fruits, vegetables, dairy, and whole grains. Limit sugary treats and drinks.
  • Drink alcohol in moderation: Too much beer, wine, or spirits can increase uric acid.
  • Stay hydrated: Drink plenty of water, at least 8-10 glasses daily.
  • Maintain a healthy weight and exercise regularly to reduce uric acid.
  • Manage stress with meditation or yoga.
  • Regular health checks: Monitor uric acid levels and follow up with your doctor to adjust your treatment plan.

What if I have taken an overdose of Inonza 1 mg Injection

As Inonza 1 mg Injection is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. If you think there has been an overdose or experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly.

Drug Warnings

Inonza 1 mg Injection should be avoided if you are allergic to it or any other components present in it. Before taking, inform your doctor if you have liver/kidney disease, diabetes, cardiac problems, or increased blood pressure, as the use of Inonza 1 mg Injection in these patients may cause serious side effects. This medicine is known to cause embryo-fetal toxicity. Hence, inform your doctor if you are pregnant or are planning to become pregnant before starting the treatment. Breastfeeding should be discontinued in nursing mothers during the treatment. Inonza 1 mg Injection is given in children above one year of age only if prescribed by the doctor. Inonza 1 mg Injection may cause myelosuppression, QT prolongation, hepatotoxicity, Hepatic Veno-occlusive Disease (Sinusoidal Obstruction Syndrome), and Increased Risk of Post-HSCT Non-Relapse Mortality in some patients. Hence, inform your doctor about your complete medical and medication history before receiving this medicine. Avoid alcohol consumption and smoking, which can lead to serious adverse effects.

Drug-Drug Interactions

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Inotuzumab ozogamicinMoxifloxacin
Severe

Drug-Drug Interactions

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Inotuzumab ozogamicinMoxifloxacin
Severe
How does the drug interact with Inonza 1 mg Injection:
Using Moxifloxacin together with Inonza 1 mg Injection can increase the risk of an irregular heart Rhythm.

How to manage the interaction:
Although taking Moxifloxacin and Inonza 1 mg Injection together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you notice any of these symptoms - an irregular heartbeat, dizziness, difficulty breathing- make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • After beginning your treatment, several dietary adjustments can help you control side effects.
  • Anyone suffering from a chronic illness, including cancer, should consume foods high in protein, healthy fats, whole grains, and vitamins and minerals.
  • Plant-based proteins are among the greatest meals to take during chemotherapy or other cancer treatments. They have the highest concentrations of vitamins and minerals, such as nuts, seeds, beans, and legumes.
  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.
  • Avoid fast and fried food, processed meats, refined carbs and added sugars.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

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Alcohol

Caution

Avoid consuming alcohol while on treatment with Inonza 1 mg Injection as it may cause severe side effects.

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Pregnancy

Unsafe

Inform your doctor if you are pregnant or intend to get pregnant. You should not become pregnant while receiving Inonza 1 mg Injection and for at least eight months following your last dosage. Consult your doctor about birth control techniques that will work for you. If you are a man, you and your female partner should use birth control during therapy and for at least five months following your last dosage. Call your doctor if you or your partner become pregnant while on treatment with this medicine. It may be harmful to the fetus.

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Breast Feeding

Unsafe

If you are breastfeeding, notify your doctor. Your doctor may advise you not to breastfeed during your Inonza 1 mg Injection treatment and for at least two months following the last dose.

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Driving

Caution

Inonza 1 mg Injection is administered in the hospital setting. Hence, driving is not recommended.

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Liver

Caution

If you have a pre-existing or a history of liver problems, tell your doctor before receiving this medicine. Inonza 1 mg Injection is known to cause hepatotoxicity, which may be fatal. If you have any symptoms such as yellowing of your skin or the white part of your eyes (jaundice), dark or brown (tea-coloured) urine, abdominal pain, bleeding more easily than normal, or tiredness while taking Inonza 1 mg Injection inform your doctor.

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Kidney

Caution

If you have a pre-existing or a history of kidney diseases, inform your doctor before receiving Inonza 1 mg Injection. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Unsafe

Inonza 1 mg Injection is not recommended for children as the safety and effectiveness were not established.

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Heart

Inonza 1 mg Injection should be used with caution and under medical supervision in patients with heart problems. Therefore, please consult your doctor before using Inonza 1 mg Injection.

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Geriatrics

Consult your doctor

Please consult a doctor before administering Inonza 1 mg Injection to geriatric patients. Your doctor will prescribe Inonza 1 mg Injection if the benefits outweigh the risks.

FAQs

Inonza 1 mg Injection is used to treat Acute lymphocytic leukemia (ALL).

Inonza 1 mg Injection contains Inotuzumab Ozogamicin, which works by inhibiting the DNA transcription that is essential for cancer cell growth. This helps prevent the growth and further spread of cancerous or non-cancerous cells.

Inonza 1 mg Injection is known to cause embryo-fetal toxicity; hence, it is contraindicated for use in pregnancy. A woman must have a negative pregnancy test before starting treatment with this medicine. Using effective birth control methods to prevent pregnancy while taking this medicine is better.

Country of origin

India

Manufacturer/Marketer address

The Capital, 1802, 18Th Floor , Plot No. C-70, €˜G’ Block , Bandra Kurla Complex, Bandra East , Mumbai €“ 400051
Other Info - INO0069

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Author Details

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Sep 18, 2025 | 11:51 AM IST

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Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/761040s000lbl.pdf
  2. https://besponsa.pfizerpro.com/
  3. https://medlineplus.gov/druginfo/meds/a617041.html
  4. https://www.cancerresearchuk.org/about-cancer/treatment/drugs/inotuzumab-ozogamicin
  5. https://go.drugbank.com/drugs/DB05889
  6. https://www.drugs.com/mtm/inotuzumab-ozogamicin.html

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