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compositionComposition:INFLIXIMAB-100MG
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Prescription Medicine
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₹24354 with coupons & bank offers*

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Infimab Injection is used in the treatment of Rheumatoid arthritis, Ankylosing spondylitis, Psoriatic arthritis, Plaque psoriasis, Crohn's disease and Ulcerative colitis. It consists of Infliximab, which works by inhibiting the TNF-α and TNF-β binding to the cell surface, thereby making the TNF cytokine inactive. This helps reduce inflammation and pain caused by various autoimmune diseases.

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Written By Dr. Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

INFLIXIMAB-100MG

Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Infimab Injection

Infimab Injection is a prescription medicine used to reduce inflammation and manage symptoms in adults and children with moderate-to-severe inflammatory conditions. It is commonly prescribed for diseases like Crohn's disease, ulcerative colitis, rheumatoid arthritis, plaque psoriasis, and certain types of spinal arthritis. By targeting the source of swelling and pain, this medication helps bring chronic symptoms under control.

This medicine is given as an intravenous infusion (a slow injection into a vein) by a healthcare professional, usually every few weeks after an initial starter phase. Because it is injected directly into the bloodstream, your food intake does not affect how the medicine works. Along with your regular medical treatments, adopting specific diet and lifestyle changes tailored to your condition can help you achieve better, more consistent results.

Like all biologic medicines, Infimab Injection can cause side effects. Some people may experience mild issues like headaches, sinus congestion, or stomach discomfort. However, because this medicine affects your immune system, it is important to watch for serious side effects like severe infections, breathing difficulties, or allergic reactions, and to contact your doctor immediately if they occur.

Before you begin treatment, it is vital to discuss your medical history with your doctor. Do not take this if you have a severe, active infection or moderate-to-severe heart failure. You must also tell your healthcare provider if you have ever had tuberculosis, hepatitis B, or a history of nervous system disorders.

This medicine can interact with other treatments, especially other biologic drugs and live vaccines, which can increase your risk of serious infections. Smoking can also reduce the effectiveness of the treatment and worsen your condition. If you are pregnant, breastfeeding, planning a family, or are an older adult, talk to your doctor or pharmacist to weigh the risks and benefits carefully.

Uses of Infimab Injection

Infimab Injection is used to treat several chronic inflammatory and autoimmune conditions by reducing abnormal immune system activity. Its approved uses include:

  • Crohn's disease: Helps reduce inflammation in the digestive tract, relieving symptoms such as abdominal pain and diarrhoea while promoting healing of the bowel lining in both adults and children.
  • Ulcerative colitis: Targets inflammation in the large intestine to help achieve and maintain remission.
  • Rheumatoid arthritis: Used together with other medicines to reduce joint pain, stiffness, and swelling while helping prevent permanent joint damage.
  • Plaque psoriasis: Helps clear moderate-to-severe psoriasis plaques, reducing redness, scaling, and discomfort.
  • Ankylosing spondylitis: Reduces inflammation in the joints of the spine, relieving chronic back pain and improving mobility.
  • Psoriatic arthritis: Controls joint pain and swelling while improving skin symptoms, making daily activities easier.

Key Benefits

Infimab Injection helps control chronic inflammation, relieve symptoms, improve daily functioning, and reduce long-term disease-related damage. Its key benefits include:

  • Provides long-term inflammation control: Targets the underlying inflammatory process to reduce flare-ups and promote healing of affected tissues.
  • Improves mobility and daily comfort: Reduces joint pain, stiffness, swelling, and other symptoms, helping you stay active and perform everyday tasks more comfortably.
  • Helps prevent disease progression: By controlling ongoing inflammation, it helps reduce long-term damage to joints, the digestive tract, skin, and other affected organs.
Side effects of Infimab Injection
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the steps to manage the medication-triggered Sinusitis (Sinus infection or Inflammation Of Sinuses):
  • Consult your doctor if you experience symptoms of sinusitis, such as nasal congestion, facial pain, or headaches, which may be triggered by your medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your sinusitis symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • If your doctor advises, you can use nasal decongestants or saline nasal sprays to help relieve nasal congestion and sinus pressure.
  • To help your body recover, get plenty of rest, stay hydrated, and engage in stress-reducing activities. If your symptoms persist or worsen, consult your doctor for further guidance.
  • Drink warm fluids such as warm water with honey, broth, soup or herbal tea to soothe sore throat.
  • Gargle with warm salt water.
  • Suck on lozenges to increase the production of saliva and soothe your throat.
  • Use a humidifier to soothe sore throat as it adds moisture to the air and makes breathing easier.
Managing Medication-Triggered Bronchitis (Inflammation of the bronchial tubes): A Step-by-Step Guide:
  • If you experience symptoms like coughing, wheezing, chest tightness, or difficulty breathing after taking medication, seek medical attention immediately.
  • Your healthcare provider will work with you to stop the medication causing the reaction, start alternative treatments, and provide supportive therapy.
  • To manage symptoms and prevent complications, follow your doctor's advice to use inhalers or nebulizers as prescribed, practice good hygiene, avoid irritants, stay hydrated, and get plenty of rest.
  • Regularly track your symptoms and report any changes or concerns to your healthcare provider.
Here are the steps to manage the medication-triggered Upper respiratory tract infection:
  • Inform your doctor about the symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids to help loosen and clear mucus from your nose, throat, and airways.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
  • Focus on eating nutrient-rich foods such as citrus fruits, spinach, ginger, garlic, turmeric, and fermented foods to improve immunity and general health.
  • Drink plenty of water to stay hydrated, and think about taking probiotics, zinc, vitamin C, and vitamin D supplements.
  • Adopt healthful practices such as leading a balanced lifestyle and remaining at home when necessary.
Here are the seven steps to manage medication-triggered Dyspnea (Difficulty Breathing or Shortness of Breath):
  • Tell your doctor immediately if you experience shortness of breath after taking medication.
  • Your doctor may adjust the medication regimen or dosage or give alternative medical procedures to minimize the symptoms of shortness of breath.
  • Monitor your oxygen levels and breathing rate regularly to track changes and potential side effects.
  • For controlling stress and anxiety, try relaxation techniques like deep breathing exercises, meditation, or yoga.
  • Make lifestyle changes, such as quitting smoking, exercising regularly, and maintaining a healthy weight.
  • Seek emergency medical attention if you experience severe shortness of breath, chest pain, or difficulty speaking.
  • Follow up regularly with your doctor to monitor progress, adjust treatment plans, and address any concerns or questions.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication.
  • Infimab Injection will be administered by a nurse or doctor.
  • Do not self-administer.

How Infimab Injection Works

Infimab Injection contains infliximab, a monoclonal antibody that helps reduce inflammation by targeting an overactive immune response. Infimab Injection works by binding to and blocking tumour necrosis factor-alpha (TNF-alpha), a protein produced by the immune system that plays an important role in inflammation. In certain inflammatory diseases, the body produces excessive amounts of TNF-alpha, causing the immune system to attack healthy tissues and leading to ongoing inflammation, pain, and tissue damage. By neutralising excess TNF-alpha, Infimab Injection helps calm the overactive immune system and interrupts the inflammatory process. This reduces inflammation, relieves symptoms, and helps prevent further damage to affected tissues and organs. Together, these actions help reduce pain, swelling, and stiffness, improve physical function, and help control chronic inflammatory conditions.
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Alcohol

Consult your doctor

It is not known if alcohol interacts with Infimab Injection. Please consult the doctor.

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Pregnancy

Caution

If you are pregnant or planning pregnancy, inform your doctor before receiving Infimab Injection. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Caution

It is not known whether Infimab Injection passes into human milk. Hence, if you are breastfeeding, inform your doctor before receiving Infimab Injection.

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Driving

Caution

Infimab Injection will be administered in the hospital setting. Hence, driving and operating machines is not recommended.

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Liver

Caution

If you have liver disease, inform your doctor before receiving Infimab Injection. Some patients using $namr have suffered significant liver issues in rare situations. Inform your doctor if you have jaundice (yellowing skin and eyes), dark brown urine discomfort (right-sided abdominal ache, extreme exhaustion (severe fatigue) as a result of a fever.

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Kidney

Caution

If you have kidney impairment, tell your doctor before taking Infimab Injection.

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Children

Safe if prescribed

Infimab Injection is not recommended in children below six years of age as safety and efficacy are not established. In children above six years of age, it will be administered by the pediatrician. Infimab Injection is used in children only for the treatment of juvenile idiopathic arthritis, paediatric Crohn’s disease, and ulcerative colitis.

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Heart

Caution

Infimab Injection should be used with caution and under medical supervision in patients with heart problems. Therefore, please consult your doctor before using Infimab Injection.

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Geriatrics

Caution

Infimab Injection should be used with caution in geriatric patients due to increased risk of age-related side effects. Therefore, please consult your doctor before giving Infimab Injection to elderly individuals.

What if I have taken an overdose of Infimab Injection

Because a trained medical professional prepares and gives this injection, an accidental overdose is highly unlikely. However, if you experience severe symptoms or suspect an error during your treatment, inform the clinic staff immediately or seek emergency medical care.

Diet & Lifestyle Advise

  • Eat an anti-inflammatory diet: Focus on whole foods, lean proteins, and omega-3 fatty acids. If you are treating Crohn's or colitis, identify your personal 'trigger foods' (like spicy dishes, high-fibre foods during flares, or caffeine) and avoid them.
  • Stay well-hydrated: Drink plenty of water, especially on the day of your infusion. Good hydration makes it easier for the nurse to find a vein and helps your body process the treatment smoothly.
  • Practice low-impact exercise: Activities like walking, swimming, or gentle yoga can help keep your joints flexible and reduce stiffness without causing excess physical stress.
  • Avoid live vaccines: Always consult your doctor before getting any immunisations, as live vaccines can be dangerous while your immune system is suppressed by this medicine.
  • Avoid smoking: Smoking can worsen inflammatory conditions, reduce the effectiveness of Infimab Injection, and increase your risk of cardiovascular complications.
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How Soon It Starts Working

The time required for Infimab Injection to start to work: The time required for Infimab Injection to show its action is not clinically established. The time for which the effects of Infimab Injection last: The duration of action for Infimab Injection is not clinically established.

What if you forget to take Infimab Injection

Since this medicine is injected by a healthcare provider at a clinic, you cannot dose yourself at home. If you miss an appointment or need to reschedule, contact your doctor's office immediately to set up your next infusion. Keeping a consistent schedule is very important to prevent your symptoms from returning.

Storage

•Store the unused vials in a refrigerator between 2°C and 8°C. Do not freeze the medicine.
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Keep Refrigerated. Do not freeze.Prepaid payment required.

Drug Warnings

  • Inspect the infusion solution: Before your infusion, ensure the solution is clear to light yellow or slightly pearly. Do not use it if it is heavily discoloured or contains large visible particles.
  • Report infusion reactions immediately: Tell your nurse or doctor straight away if you experience warmth, itching, dizziness, difficulty breathing, or any other unusual symptoms during the infusion, as the infusion may need to be slowed or temporarily stopped.
  • Complete recommended screening tests: Get tested for tuberculosis (TB) and hepatitis B before starting treatment, as Infimab Injection can reactivate dormant infections.
  • Avoid exposure to infections: Stay away from people with contagious illnesses such as influenza or chickenpox, as your immune system may be less able to fight infections.
  • Inform healthcare providers before procedures: Tell your doctor, dentist, or surgeon that you are receiving Infimab Injection before any medical or dental procedure, as your treatment schedule may need to be adjusted to reduce the risk of infection.

Drug-Drug Interactions

verifiedApollotooltip

The following medicines may interact with Infimab Injection:

  • Other biologic medicines: Using Infimab Injection together with other biologic immunosuppressants can significantly increase the risk of serious or life-threatening infections.
  • Live vaccines: Do not receive live vaccines, such as the yellow fever vaccine or the nasal spray influenza vaccine, during treatment, as they may cause serious infections.
InfliximabMelphalan
Severe
InfliximabCarmustine
Severe

Drug-Drug Interactions

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InfliximabMelphalan
Severe
How does the drug interact with Infimab Injection:
Co-administration of Infimab Injection with Melphalan can increase the serious infection.

How to manage the interaction:
There may be a possibility of interaction between Melphalan and Infimab Injection, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
InfliximabCarmustine
Severe
How does the drug interact with Infimab Injection:
When Carmustine is taken with Infimab Injection it can increase the risk or severity of developing serious infections.

How to manage the interaction:
There may be a possibility of interaction between Infimab Injection and Carmustine, but it can be taken if prescribed by a doctor. If you have any of these symptoms like fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, losing weight, or experiencing pain or burning while urinating, it's important to contact a doctor right away. Do not stop using any medications without a doctor's advice.
InfliximabClozapine
Severe
How does the drug interact with Infimab Injection:
When Clozapine is taken with Infimab Injection, it can increase the risk or severity of developing serious infections.

How to manage the interaction:
Taking Infimab Injection with Clozapine together can result in an interaction, but it can be taken if a doctor has advised it. If you're having any of these symptoms like fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor right away. Do not stop using any medications without a doctor's advice.
InfliximabFluorouracil
Severe
How does the drug interact with Infimab Injection:
Using Infimab Injection together with fluorouracil can increase the risk or severity of developing serious infections.

How to manage the interaction:
Taking Infimab Injection together with fluorouracil together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
InfliximabOxaliplatin
Severe
How does the drug interact with Infimab Injection:
Combining Infimab Injection with Oxaliplatin can increase the risk or severity of developing serious infections.

How to manage the interaction:
Co-administration of Oxaliplatin with Infimab Injection can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
InfliximabBudesonide
Severe
How does the drug interact with Infimab Injection:
Coadministration of Budesonide and Infimab Injection can increase the risk or severity of developing serious infections.

How to manage the interaction:
There may be a possibility of interaction between Budesonide and Infimab Injection, but it can be taken if prescribed by a doctor. However, if you have any of these symptoms like fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, and pain or burning when you pee, it's important to contact a doctor right away. Do not stop using any medications without talking to a doctor.
InfliximabDeflazacort
Severe
How does the drug interact with Infimab Injection:
Co-administration of Infimab Injection with Certolizumab may increase the risk of serious infections.

How to manage the interaction:
Although there is a possible interaction between Deflazacort and Infimab Injection, you can take these medicines together if prescribed by your doctor. If you have any of the symptoms like fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, and pain or burning when you urinate, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
InfliximabBasiliximab
Severe
How does the drug interact with Infimab Injection:
Combining Infimab Injection with Basiliximab can increase the risk or severity of developing infections.

How to manage the interaction:
Taking Basiliximab with Infimab Injection together can result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms like fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, and pain or burning when you pee, contact a doctor right away. Do not stop using any medications without talking to a doctor.
InfliximabNiraparib
Severe
How does the drug interact with Infimab Injection:
Taking Niraparib with Infimab Injection can increase the risk or severity of developing serious infections.

How to manage the interaction:
Taking Niraparib with Infimab Injection together can result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms like fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, and pain or burning when you pee, it's important to contact a doctor right away. Do not stop using any medications without talking to a doctor.
InfliximabVenetoclax
Severe
How does the drug interact with Infimab Injection:
When Venetoclax is taken with Infimab Injection, it can lead to or increase the risk or severity of developing serious infections.

How to manage the interaction:
Taking Infimab Injection with Venetoclax together can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience symptoms of fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in sputum, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • No clinically significant food interactions are known with Infimab Injection when used as directed.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[IMMUNOSUPPRESSANTS]

FAQs

Infimab Injection is used to treat Rheumatoid arthritis, Ankylosing spondylitis, Psoriatic arthritis, Plaque psoriasis, Crohn’s disease and Ulcerative colitis.
Infimab Injection contains Infliximab, which works by inhibiting the TNF-α and TNF-β binding to the cell surface, thereby making the TNF cytokine inactive.
Infimab Injection affects your immune system and makes you more susceptible to infections. Hence, it is not recommended for patients with active infections like tuberculosis or abnormal liver enzymes. Infimab Injection can also increase the risk of developing cancers; hence, informing your doctor if you have a history of any cancer is essential.
Yes, Infimab Injection is an immunosuppressant. It works by inhibiting the action of tumour necrosis factor-alpha (TNF-alpha), a protein that promotes inflammation and immune responses. By suppressing the immune system, Infimab Injection can help reduce inflammation and alleviate symptoms of autoimmune diseases.
Infimab Injection is a highly effective treatment for autoimmune diseases, offering many benefits that can outweigh its potential side effects. With proper medical care, you can minimize risks and maximize benefits, improving symptoms, increased mobility, and a better quality of life.
Yes, Infimab Injection can cause liver damage in some people, though it is rare. If you have pre-existing liver conditions like hepatitis, your doctor may monitor your liver function more closely during treatment. Be sure to report any symptoms, such as unexplained fatigue, yellowing of the skin or eyes (jaundice), dark urine, or pain in the upper right abdomen, as these could indicate liver problems.
While Infimab Injection can have potential effects on the heart, it's essential to note that these risks are rare and typically occur within 24 hours of starting treatment. You can minimise possible risks and ensure safe treatment by closely monitoring your heart health and promptly reporting any symptoms to your doctor.
Infimab Injection may cause common side effects such as nausea, headache, back pain, upper respiratory tract infections, vision problems, dizziness, pale skin, numbness, chest pain, rash, and injection site reactions. Most of these side effects do not require medical attention or resolve over time. However, if they persist for longer, please consult your doctor.
You can receive non-live (inactivated) vaccines, but you must avoid live vaccines while on this treatment because your immune system is less active. Talk to your doctor or pharmacist before scheduling any vaccinations.
This medicine weakens your immune system, which can allow a quiet, inactive TB infection to become active and dangerous. Your doctor must confirm you do not have TB before you start. Talk to your doctor for more information.
This medicine should only be used during pregnancy or breastfeeding if clearly needed. Because it can cross the placenta and pass into breast milk, you must talk to your doctor to weigh the benefits against the potential risks to your baby.
No, this medicine is not a cure. It is designed to manage and control your symptoms by reducing chronic inflammation, helping you achieve and stay in remission. Talk to your doctor about your long-term treatment goals.
While there is no direct interaction between this medicine and alcohol, alcohol can increase strain on your liver and worsen certain symptoms of inflammatory diseases. Talk to your doctor or pharmacist about what is safe for you.
Because this medicine lowers your body's ability to fight infections, even a mild fever can be a sign of a serious issue. Contact your doctor immediately if you develop a fever, chills, or a cough. Talk to your doctor before taking any fever-reducing medicines.
It is given as an intravenous (IV) infusion, which means it is slowly injected into a vein in your arm by a trained healthcare professional in a clinic or hospital setting. Talk to your doctor if you have questions about the infusion process.

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Country of origin

India

Manufacturer/Marketer address

SUN HOUSE, CTS No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Other Info - INF0228
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