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compositionComposition:IDEBENONE-45MG
prescription
Prescription Medicine
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Idebest Tablet is used to treat Friedreich ataxia (neurodegenerative movement disorder) and Leber’s hereditary optic neuropathy, LHON (inherited form of vision loss). It contains Idebenone which provides the energy for the inactive cells to work normally, thereby improving lost vision in patients with LHON. Also, it helps to reduce damage to the nervous system and the heart in Friedreich ataxia.

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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Composition :

IDEBENONE-45MG

Manufacturer/Marketer :

Linux Laboratories Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Idebest Tablet

Idebest Tablet is a prescription medication used to treat vision impairment in adolescents and adults with Leber’s Hereditary Optic Neuropathy (LHON). This rare genetic condition damages the cells in the optic nerve, leading to a rapid and painless loss of eyesight. By protecting these vital nerve cells, this medicine helps maintain and potentially recover visual clarity.

For this medicine to work effectively, you must take it consistently every day as prescribed by your doctor. It is typically taken three times a day, and you should always take your doses with food to ensure your body absorbs the medication properly. Combining this therapy with specific lifestyle changes, such as avoiding smoking and eating antioxidant-rich foods, can help support your treatment results.

Most patients tolerate this medicine well, though some may experience mild side effects like diarrhoea, a runny nose, or a change in urine colour. However, you must contact your doctor immediately if you experience signs of liver damage, such as yellowing of your skin or eyes, severe stomach pain, or unusually dark urine.

Do not take this if you have moderate to severe liver damage. Before starting your treatment, tell your doctor if you have any pre-existing liver problems, kidney issues, or if you have had an allergic reaction to this medication in the past.

Certain medications may interact with Idebest Tablet , changing how it works or increasing your risk of side effects. You should also avoid drinking alcohol during treatment, as it can strain your liver and worsen eye nerve damage. If you are pregnant, planning to become pregnant, breastfeeding, or are an elderly patient, discuss the risks and benefits thoroughly with your doctor before starting.

Uses of Idebest Tablet

Idebest Tablet is used to treat vision loss associated with specific inherited disorders by protecting nerve cells and supporting visual recovery, including:

  • Leber’s Hereditary Optic Neuropathy (LHON): Idebest Tablet is used to treat visual impairment in patients with this genetic eye disorder by preventing further loss of sight and helping to restore lost vision.

Key Benefits

Idebest Tablet offers several important benefits that help preserve vision, protect optic nerve cells, and support long-term visual function, including:

  • Helps Preserve Vision: Idebest Tablet helps slow the progression of vision loss in people with Leber's Hereditary Optic Neuropathy (LHON), helping maintain useful eyesight.
  • Supports Visual Recovery: In some patients, treatment may improve visual function, making everyday activities such as reading, recognising faces, or navigating more manageable.
  • Protects Optic Nerve Cells: By supporting cellular energy production and reducing oxidative damage, Idebest Tablet helps protect the cells of the optic nerve from further injury.
  • Promotes Long-Term Eye Health: Early and continued treatment helps improve the chances of preserving optic nerve function and reducing permanent vision loss.
Side effects of Idebest Tablet
Here are the steps to manage the medication-triggered Cough:
  • Tell your doctor about the cough symptoms you're experiencing, which may be triggered by your medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your cough symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids, such as water, tea, or soup, to help thin out mucus and soothe your throat.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your cough persists or worsens, consult your doctor for further guidance.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Managing back pain as a side effect of medication requires a combination of self-care techniques, lifestyle modifications, and medical interventions. Here are the steps:
  • Talk to your doctor about your back pain and potential medication substitutes or dose changes.
  • Try yoga or Pilates and other mild stretching exercises to increase flexibility and strengthen your back muscles.
  • To lessen the tension on your back, sit and stand upright and maintain proper posture.
  • To alleviate discomfort and minimize inflammation, apply heat or cold packs to the afflicted area.
  • Under your doctor's supervision, think about taking over-the-counter painkillers like acetaminophen or ibuprofen.
  • Make ergonomic adjustments to your workspace and daily activities to reduce strain on your back.
  • To handle tension that could make back pain worse, try stress-reduction methods like deep breathing or meditation.
  • Use pillows and a supportive mattress to keep your spine in the right posture as you sleep.
  • Back discomfort can worsen by bending, twisting, and heavy lifting.
  • Speak with a physical therapist to create a customized training regimen to increase back strength and flexibility.

Directions for Use

  • Idebest Tablet should be taken with food for better absorption.
  • Follow your doctor’s recommendations on the dosage and timing of this medication to achieve optimal results.
  • Swallow Idebest Tablet as a whole with a glass of water.
  • Do not crush, chew, or break it.

How Idebest Tablet Works

Idebest Tablet contains idebenone, a medicine that helps protect the cells of the optic nerve and supports their energy production in people with Leber's Hereditary Optic Neuropathy (LHON). Idebest Tablet works by acting as an alternative carrier in the cell's energy-producing pathway. In LHON, genetic mutations damage the mitochondria, reducing the cells' ability to produce energy. Idebest Tablet bypasses the damaged part of this pathway, helping restore energy production within the cells. It also acts as an antioxidant, protecting optic nerve cells from oxidative damage and reducing further cell injury. Together, these actions help support the survival and function of optic nerve cells, which may slow vision loss and improve or stabilise vision in some people with LHON.
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Alcohol

Caution

Do not consume alcohol while taking Idebest Tablet as it may cause unpleasant side effects.

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Pregnancy

Caution

It is not known whether Idebest Tablet is safe to be used in pregnancy. Please consult your doctor before taking this medicine. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Caution

Idebest Tablet may pass into breastmilk and cause harm to your infant. So, caution should be exercised, and it is advisable to consult your doctor before using it.

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Driving

Safe if prescribed

Idebest Tablet may not affect your ability to drive.

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Liver

Caution

There is insufficient data to establish the safe use of Idebest Tablet in patients with liver disease. Please consult your doctor. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Caution

There is insufficient data to establish the safe use of Idebest Tablet in patients with kidney diseases. Please consult your doctor. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Unsafe

Idebest Tablet is not recommended for use in children below 12 years of age.

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Heart

Consult your doctor

Idebest Tablet can be used in heart patients if prescribed by the physician. Please consult your physician if you have any concerns.

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Geriatrics

Safe if prescribed

Idebest Tablet is safe for use in elderly patients if prescribed by the physician.

What if I have taken an overdose of Idebest Tablet

If you take more than your prescribed dose, seek immediate emergency medical attention or contact a poison control center. Bring the medication package with you to show the medical team.

Diet & Lifestyle Advise

  • Strictly avoid smoking: Tobacco smoke is a known trigger that accelerates vision loss in LHON by further damaging cell mitochondria. Avoid firsthand and secondhand smoke completely.
  • Avoid or minimise alcohol: Alcohol increases cellular stress and can worsen the underlying nerve damage in your eyes.
  • Eat a nutrient-dense diet: Focus on foods high in natural antioxidants, such as berries, spinach, kale, and nuts, to support overall eye and nerve health.
  • Always pair with food: Ensure every dose is taken with a fat-containing meal or snack to guarantee optimal absorption.

Health Queries

I developed traumatic optic atrophy after a road traffic accident and am worried about my vision. Are there any treatments or supportive therapies that may help protect or improve the remaining eyesight?

Vikas Singh

Vikas Singh

M Pharmacy

Traumatic optic atrophy can develop after a head or eye injury when the optic nerve becomes damaged from swelling, reduced blood supply, or direct trauma. Vision loss may remain stable in some people, while others may notice gradual changes depending on the severity of nerve injury. Once nerve fibres are significantly damaged, complete recovery can be difficult, but protecting the remaining vision is still very important. Treatment usually focuses on identifying any ongoing pressure, inflammation, or related eye problems that may worsen the damage. Doctors may advise regular eye monitoring, vitamin support if deficiencies are present, controlling diabetes or blood pressure, and refraining from smoking or alcohol, because they may additionally affect nerve health. Low-vision aids, magnifiers, brighter lighting and visual rehabilitation training can help improve daily activities and independence. Protective eyewear and fall prevention are also important if vision has been reduced significantly. Some research on nerve regeneration and stem-cell therapy is ongoing, but these treatments are still experimental. Seek urgent ophthalmology care if vision suddenly worsens, severe eye pain develops, or new neurological symptoms appear.

My family member has been diagnosed with optic neuropathy, and doctors said it may be a progressive condition with limited treatment options. We are trying to protect the remaining vision. Are there any treatments, therapies, or supportive measures that may help slow the vision loss or improve eye health?

Vikas Singh

Vikas Singh

M Pharmacy

Optic neuropathy happens when the optic nerve, which carries signals from the eye to the brain, becomes damaged. Vision loss may progress slowly or quickly depending on the cause. Some cases are due to reduced blood supply, inflammation, nutritional deficiency, genetic conditions, diabetes, infections, or pressure on the nerve. Protecting the remaining vision usually focuses on treating the underlying cause and reducing further nerve damage. Doctors may advise vitamin support, controlling blood sugar and blood pressure, stopping smoking and alcohol, protecting the eyes from strain, and managing nutritional deficiencies if present. In certain cases, steroid treatment, immune therapy, or surgery may help when inflammation or pressure is involved. Regular follow-up with a neuro-ophthalmologist is important to monitor vision changes and nerve health. Low-vision aids, brighter lighting, magnifiers, and visual rehabilitation therapy may also improve daily functioning and quality of life. Seek urgent medical attention if there is sudden major vision loss, severe eye pain, double vision, weakness, or difficulty speaking.

I am suffering from Spinocerebellar Ataxia Type 3 and want to know if there is any treatment, therapy, or cure available that may help manage the condition and improve my quality of life?

Vikas Singh

Vikas Singh

M Pharmacy

Spinocerebellar Ataxia Type 3 is a progressive neurological condition that affects balance, coordination, speech, walking, and muscle control. At present, there is no complete cure that can permanently stop or reverse the disease, but several supportive treatments may help improve daily functioning and quality of life. Symptoms often progress slowly over time, so regular care and rehabilitation are important. Management usually focuses on physiotherapy, balance training, stretching exercises, speech therapy, and occupational therapy to help maintain movement and independence for as long as possible. Doctors may sometimes prescribe medicines for stiffness, muscle cramps, tremors, sleep problems, depression, or pain, depending on individual symptoms. Nutritious food, proper sleep, emotional support, fall prevention, and assistive devices like walkers or support rails may also improve safety and comfort. Neurology follow-up is important because treatment plans often change as symptoms progress. Research on gene-targeted therapies is ongoing, although these treatments are still developing. Inform your doctor if you experience difficulty swallowing, frequent falls, breathing trouble, or rapid worsening of symptoms.
health query

Have a query?

How Soon It Starts Working

The time required for Idebest Tablet to start to work: Idebest Tablet ideally shows its action within 2 to 4 hours after administration. The time for which the effects of Idebest Tablet last: The effect of Idebest Tablet lasts for 12 hours.

What if you forget to take Idebest Tablet

If you miss a dose, take it as soon as you remember with food. If your next scheduled dose is less than 2 hours away, skip the missed dose and resume your regular schedule. Do not take a double dose to make up for a missed one.

Storage

•Store Idebest Tablet at room temperature, ideally between 15°C and 25°C.

Drug Warnings

  • Check your urine colour: Do not be alarmed if your urine turns reddish-brown; this is a harmless effect of the medicine passing through your body.
  • Monitor your liver health: Your doctor may order blood tests to check your liver function before and during your treatment. Attend all scheduled lab appointments.
  • Inspect your tablets: Always check the physical appearance of your tablets before swallowing. Do not use them if they are broken, discoloured, or show signs of moisture damage.
  • Keep a consistent schedule: Set an alarm to ensure you take your doses at evenly spaced intervals throughout the day.

Drug-Drug Interactions

verifiedApollotooltip

Idebest Tablet may interact with certain medicines, affecting how they work or increasing the risk of side effects. Inform your doctor about all prescription medicines, over-the-counter products, vitamins, and herbal supplements you are taking, including:

  • Medicines Metabolised by Liver Enzymes: May interact with medicines processed by specific liver enzymes. This can increase the levels or modify the effects of drugs like certain blood thinners, blood pressure medications, or antihistamines. Always share your complete list of medicines with your doctor.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

verifiedApollotooltip

Certain foods and beverages may affect how well Idebest Tablet is absorbed or processed by your body. To achieve the best treatment results, keep the following in mind:

  • Food: Taking this medication on an empty stomach significantly lowers its absorption. Always take it with food.
  • Grapefruit and Grapefruit Juice: Avoid consuming grapefruit or grapefruit juice, as it may interfere with how your body processes this medicine.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIOXIDANTS]

FAQs

Idebest Tablet is used to treat Friedreich ataxia and Leber’s hereditary optic neuropathy (LHON). Friedreich ataxia is a rare inherited disorder that causes difficulty walking and speech impairment. LHON is an eye disease that is an inherited genetic disorder.
Idebest Tablet contains ‘Idebenone’, which is a potent antioxidant. It works by neutralizing the free radicals in the body that cause damage to the tissues. It improves vision impairment in patients with Leber's hereditary optic neuropathy and reduces damage to the nervous system and the heart in Friedreich ataxia.
Idebest Tablet can change urine colour to reddish-brown. However, this effect is harmless and improves after discontinuation of therapy.
The common side-effects of Idebest Tablet are nasopharyngitis (cold), cough, diarrhoea, and back pain. These side effects are usually mild and temporary. However, if these side effects persist or worsen, inform your doctor immediately.
Idebest Tablet is preferably taken with food to get its maximum benefits. Take this medicine at the same time every day for the best results.
Friedreich ataxia is a rare inherited genetic condition caused by a mutation in the FXN gene. It harms the brain, spinal cord, and heart, resulting in shaky posture, trouble walking, and impaired speech.
If you take more than the prescribed dose of Idebest Tablet , you may experience increased side effects such as nausea, vomiting, diarrhea, abdominal pain, and headache. In severe cases, overdosing can lead to more serious complications. If you suspect an overdose, seek medical attention immediately.
No, you should always take Idebest Tablet with food. Food significantly increases the amount of medicine your body can absorb, making the treatment much more effective. Talk to your doctor or pharmacist if you struggle to take it with meals.
This is a very common and harmless side effect. The active substance in Idebest Tablet is naturally coloured and can tint your urine. It is not a cause for concern, but you should talk to your doctor if you also experience stomach pain or yellowing of your skin.
There is currently no absolute cure for LHON, but Idebest Tablet is clinically proven to help prevent further vision loss and can help recover some lost eyesight. Talk to your doctor for realistic expectations based on your specific case.
It is highly recommended to avoid alcohol while taking this medicine. Alcohol can increase the strain on your liver and can also directly worsen the mitochondrial damage in your optic nerves. Talk to your doctor for further guidance.
Mild diarrhoea is a common side effect of this medicine. Ensure you stay well-hydrated by drinking plenty of water. If the diarrhoea becomes severe, lasts for several days, or is accompanied by severe stomach cramps, talk to your doctor immediately.
The safety of this medicine during pregnancy has not been fully established. If you are pregnant, suspect you might be, or are planning to have a baby, talk to your doctor to weigh the benefits against potential risks before starting this treatment.
You should completely avoid smoking. Tobacco smoke is highly toxic to mitochondria, which are already struggling in patients with LHON. Smoking can severely undermine the benefits of Idebest Tablet and accelerate vision loss. Talk to your doctor if you need help quitting.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Plot no: 492, Viduthalai Nagar Extension Near JD Mahal, Pallavaram Thuraipakam Road S.Kulathur,Kovilambakkam, Chennai - 600 117
Other Info - IDE0049

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