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compositionComposition:HALOTHANE-100%W/V
prescription
Prescription Medicine
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Hypnothane Liquid For Inhalation is a general inhalation anaesthetic used to induce and maintain general anaesthesia. It contains ' Halothane', an inhaled general anaesthetic. It acts on the brain and causes unconsciousness. Halothane puts you to sleep and maintains your unconsciousness during an operation. It stops you from knowing what happens during surgical processes and other procedures.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

HALOTHANE-100%W/V

Manufacturer/Marketer :

Neon Laboratories Ltd

Consume Type :

Inhalation

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Hypnothane Liquid For Inhalation

Hypnothane Liquid For Inhalation is an inhaled general anaesthetic used to produce and maintain unconsciousness during surgery and other procedures requiring general anaesthesia. Halothane is used less commonly in many countries today because newer inhaled anaesthetics are available, but its availability and use vary by country and healthcare setting.

This medicine acts on the brain and spinal cord to produce a controlled state of unconsciousness and reduce awareness and perception of pain during a procedure. The exact way halothane produces general anaesthesia is not fully understood. Your anaesthetist will decide whether it is appropriate based on the procedure, available anaesthetic options, and your individual health needs.

This medicine is given as a vapour that you breathe through a mask or airway device under the supervision of an anaesthetist or other appropriately trained healthcare professional. The amount is carefully adjusted throughout the procedure while your breathing, heart rate, blood pressure, oxygen levels, and other vital signs are monitored.

Some people may experience nausea, vomiting, shivering, drowsiness, or confusion while recovering from general anaesthesia. Halothane can also affect blood pressure and heart rhythm and can make the heart more sensitive to the effects of certain substances such as catecholamines. Rare but serious risks include severe liver injury and malignant hyperthermia, a dangerous reaction to certain anaesthetics.

Before receiving this medicine, tell your medical team about all medicines you take and any previous reactions to anaesthesia. Tell your anaesthetist if you have liver disease, heart or heart rhythm problems, pheochromocytoma, thyroid problems, myasthenia gravis, or a personal or family history of malignant hyperthermia. Also tell them if you are pregnant, breastfeeding, or are an older adult, as these factors may affect the choice and management of anaesthesia.

Uses of Hypnothane Liquid For Inhalation

Your anaesthetist may use Hypnothane Liquid For Inhalation for the following purposes:

  • Induction of general anaesthesia: Hypnothane Liquid For Inhalation may be used to help produce a controlled state of unconsciousness before a surgical procedure.
  • Maintenance of general anaesthesia: Hypnothane Liquid For Inhalation may be used to maintain general anaesthesia during a procedure while the anaesthesia team continuously monitors and adjusts treatment.

Key Benefits

When selected by the anaesthesia team, Hypnothane Liquid For Inhalation can help provide the controlled level of general anaesthesia needed for a surgical procedure.

  • Maintains unconsciousness: It can help keep you unconscious during surgery so the procedure can be performed without awareness.
  • Supports pain control during surgery: As part of an anaesthetic plan, it reduces the perception of painful surgical stimulation while you are unconscious.
  • Allows controlled anaesthesia: The amount delivered can be adjusted by the anaesthesia team according to your response and the requirements of the procedure.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safety.
  • Hypnothane Liquid For Inhalation will be administered by a doctor or healthcare professional.
  • Do not self-administer.

How Hypnothane Liquid For Inhalation Works

Hypnothane Liquid For Inhalation contains halothane. It is an inhaled general anaesthetic that acts mainly on the brain and spinal cord. After it is breathed into the lungs, it enters the bloodstream and reaches the central nervous system. It suppresses nervous system activity, producing unconsciousness and reducing awareness and perception of pain during surgery. The exact cellular and molecular mechanisms responsible for the anaesthetic effects of halothane are not fully understood.
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Hypnothane Liquid For Inhalation .

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Pregnancy

Caution

Hypnothane Liquid For Inhalation should be used in pregnant women only if clinically needed, and the benefits outweigh the risks. So, inform your doctor before receiving the Hypnothane Liquid For Inhalation if you are pregnant or planning for pregnancy. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

Hypnothane Liquid For Inhalation is excreted into the breast milk. Breastfeeding should be stopped for 24 hours after halothane anaesthesia.

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Driving

Unsafe

Patients should not drive or operate heavy machinery for at least 24 hours after receiving halothane.

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Liver

Caution

Caution should be exercised while using Hypnothane Liquid For Inhalation in patients with liver impairment. So, inform your doctor before receiving the Hypnothane Liquid For Inhalation if you have a liver impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Caution should be exercised while using Hypnothane Liquid For Inhalation in patients with Kidney impairment. So, inform your doctor before receiving the Hypnothane Liquid For Inhalation if you have a kidney impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Caution

Children under 18 years of age undergoing dental procedures outside the hospital are not recommended to use.

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Heart

Unsafe

Hypnothane Liquid For Inhalation should not be used if you have any heart disease, as it weakens heart muscles. Please consult the doctor if you have any concerns.

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Geriatrics

Caution

Hypnothane Liquid For Inhalation should be used with caution in elderly patients. Please consult your doctor before use.

What if I have taken an overdose of Hypnothane Liquid For Inhalation

Because Hypnothane Liquid For Inhalation is administered and continuously adjusted by trained healthcare professionals, receiving too much is unlikely. If excessive anaesthetic effects occur, the healthcare team can reduce or stop halothane and provide appropriate breathing, cardiovascular, and other supportive care while monitoring you closely.

Diet & Lifestyle Advise

  • Follow fasting instructions: Follow the exact instructions from your healthcare team about when to stop eating and drinking before your procedure. Fasting requirements can vary depending on what you consume and your individual circumstances.
  • Arrange transport home: If you are discharged on the same day, arrange for a responsible adult to take you home and follow your healthcare team's instructions about supervision after anaesthesia.
  • Rest during recovery: Anaesthesia can temporarily affect coordination, judgement, and alertness. Follow your medical team's advice about driving, operating machinery, working, or making important decisions after your procedure.
  • Resume fluids and food as advised: Start drinking and eating again when your healthcare team says it is appropriate, particularly if you have nausea after the procedure.
  • Avoid alcohol and non-prescribed sedatives: Follow your healthcare team's advice about when it is safe to resume alcohol or medicines that can cause drowsiness after anaesthesia.
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How Soon It Starts Working

The time required for Hypnothane Liquid For Inhalation to start to work: The onset of time for Hypnothane Liquid For Inhalation varies based on the individual. The time for which the effects of Hypnothane Liquid For Inhalation last: The duration of Hypnothane Liquid For Inhalation effect is unknown.

What if you forget to take Hypnothane Liquid For Inhalation

Hypnothane Liquid For Inhalation is administered by healthcare professionals during a planned procedure and is not taken on a regular schedule at home. Therefore, there is no routine dose for you to miss.

Storage

• Hypnothane Liquid For Inhalation is stored and handled by healthcare professionals in facilities where it is used for anaesthesia.

Drug Warnings

  • Mention previous anaesthetic reactions: Tell your anaesthetist about any serious reaction you or a family member has had to general anaesthesia, particularly malignant hyperthermia.
  • Discuss previous liver problems: Tell your doctor if you have liver disease or previously developed unexplained liver problems after an anaesthetic. Rare severe liver injury associated with halothane can occur even after a first exposure, although previous exposure can increase the risk.
  • Share heart conditions: Halothane can affect heart rhythm and make the heart more sensitive to catecholamines. Tell your anaesthetist if you have heart disease, an abnormal heart rhythm, or take medicines that affect your heart or blood pressure.
  • Mention adrenal or thyroid conditions: Tell your anaesthetist if you have pheochromocytoma or a thyroid disorder, as these conditions may affect cardiovascular responses during anaesthesia.
  • Provide a complete medicine list: Tell your healthcare team about all prescription medicines, over-the-counter medicines, vitamins, supplements, and herbal products you use.
  • Follow recovery instructions: Remain in the recovery area until your healthcare team considers you ready for discharge and follow their instructions about activities, food, medicines, and supervision after the procedure.

Drug-Drug Interactions

verifiedApollotooltip
  • Catecholamines and related medicines (e.g. epinephrine/adrenaline): Halothane can make the heart more sensitive to catecholamines, which may increase the risk of abnormal heart rhythms. The anaesthesia team carefully controls their use when needed.
  • Beta-blockers (e.g. propranolol, metoprolol, or atenolol): These medicines may add to effects on heart rate or blood pressure during anaesthesia. Your anaesthetist will monitor your cardiovascular response closely.
  • Bronchodilators (e.g. theophylline or aminophylline): These medicines may increase the risk of abnormal heart rhythms when used with halothane, so additional monitoring may be required.
  • Opioids and sedatives (e.g. morphine, fentanyl, diazepam, or midazolam): These medicines can add to the effects of general anaesthesia, including reduced alertness and breathing. The anaesthesia team adjusts doses and monitors you closely.
HalothaneZiprasidone
Critical
HalothaneAminophylline
Severe

Drug-Drug Interactions

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HalothaneZiprasidone
Critical
How does the drug interact with Hypnothane Liquid For Inhalation 250 ml:
Taking Hypnothane Liquid For Inhalation 250 ml with Ziprasidone can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Ziprasidone with Hypnothane Liquid For Inhalation 250 ml is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
HalothaneAminophylline
Severe
How does the drug interact with Hypnothane Liquid For Inhalation 250 ml:
Using Hypnothane Liquid For Inhalation 250 ml together with aminophylline may increase the risk of cardiac side effects such as irregular heart rhythm.

How to manage the interaction:
Although there is a possible interaction between Aminophylline and Hypnothane Liquid For Inhalation 250 ml, you can take these medicines together if prescribed by your doctor. If you experience irregular heart rhythm or any complications, it is important to contact a doctor right away. Do not stop using any medications without a doctor's advice.
HalothaneHaloperidol
Severe
How does the drug interact with Hypnothane Liquid For Inhalation 250 ml:
Co-administration of Hypnothane Liquid For Inhalation 250 ml and Haloperidol can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Co-administration of Hypnothane Liquid For Inhalation 250 ml and Haloperidol can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
HalothaneTirzepatide
Severe
How does the drug interact with Hypnothane Liquid For Inhalation 250 ml:
Tirzepatide may cause the stomach to take longer to empty, which raises the possibility of vomiting during anesthesia and the inhalation of stomach contents into the lungs.

How to manage the interaction:
Before undergoing surgery or a procedure, inform doctor if on tirzepatide treatment. Doctor may temporarily stop the treatment or take further precautions to reduce the risks.
HalothaneMoxifloxacin
Severe
How does the drug interact with Hypnothane Liquid For Inhalation 250 ml:
Using Moxifloxacin together with Hypnothane Liquid For Inhalation 250 ml can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Moxifloxacin with Hypnothane Liquid For Inhalation 250 ml can result in an interaction, but it can be taken if a doctor has advised it. If you experience dizziness, difficulty breathing, or fast or irregular heartbeat consult a doctor. Do not discontinue any medications without consulting a doctor.
HalothaneAmiodarone
Severe
How does the drug interact with Hypnothane Liquid For Inhalation 250 ml:
Coadministration of Hypnothane Liquid For Inhalation 250 ml with amiodarone may increase the risk of abnormal cardiac rhythms.

How to manage the interaction:
Although taking Hypnothane Liquid For Inhalation 250 ml with amiodarone may cause an interaction, it is safe to do so if your doctor has prescribed it. If you have a cardiac problem or electrolyte imbalances, you may be more vulnerable. If you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or a rapid heartbeat, consult a doctor . Do not stop taking any medications without visiting a doctor.
HalothaneClozapine
Severe
How does the drug interact with Hypnothane Liquid For Inhalation 250 ml:
Co-administration of Clozapine with Hypnothane Liquid For Inhalation 250 ml can increase the risk of irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Clozapine with Hypnothane Liquid For Inhalation 250 ml together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these signs - like an irregular heart rhythm, a heart condition, or prolonged diarrhea - make sure to contact a doctor right away. Other symptoms to watch out for include sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
HalothaneChloroquine
Severe
How does the drug interact with Hypnothane Liquid For Inhalation 250 ml:
Using chloroquine together with Hypnothane Liquid For Inhalation 250 ml can increase the risk of an irregular heart rhythm.

How to manage the interaction:
There may be a possibility of interaction between Hypnothane Liquid For Inhalation 250 ml and Chloroquine, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
HalothaneDisopyramide
Severe
How does the drug interact with Hypnothane Liquid For Inhalation 250 ml:
The combined use of Hypnothane Liquid For Inhalation 250 ml and Disopyramide can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Hypnothane Liquid For Inhalation 250 ml and Disopyramide can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
HalothaneCeritinib
Severe
How does the drug interact with Hypnothane Liquid For Inhalation 250 ml:
Taking ceritinib together with Hypnothane Liquid For Inhalation 250 ml can increase the risk of an irregular heart rhythm and other side effects.

How to manage the interaction:
Although there is a interaction between ceritinib and Hypnothane Liquid For Inhalation 250 ml, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • Food and drink before anaesthesia: Food does not directly interact with halothane, but eating or drinking too close to general anaesthesia can increase the risk of stomach contents entering the lungs. Follow the fasting instructions provided by your healthcare team.
  • Alcohol: Alcohol can affect the central nervous system and may alter your response to anaesthesia. Tell your anaesthetist about your alcohol use and follow their instructions before and after the procedure.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[GENERAL ANESTHETICS]

FAQs

Hypnothane Liquid For Inhalation is used for the induction and maintenance of general anaesthesia.
Hypnothane Liquid For Inhalation may affect your heart rhythm. Disturbances of the heart rhythm are very common. Your anaesthetist will quickly deal with any problems that arise during your operation.
Exposure to halothane within three months should be avoided unless there are strong reasons. Your anaesthetist will weigh the benefits and the risks.
Halothane is used less commonly in many countries today because newer inhaled anaesthetics, such as sevoflurane, desflurane, and isoflurane, are available. Its availability and use vary between countries and healthcare settings. Your anaesthetist will select an anaesthetic based on your health, the procedure, available options, and other clinical factors.
This medicine suppresses activity in the brain and spinal cord, producing unconsciousness and reducing awareness and perception of pain. The exact cellular mechanisms responsible for halothane's anaesthetic effects are not fully understood.
Follow the fasting instructions provided by your healthcare team. You may need to stop certain foods and drinks for a period before general anaesthesia to reduce the risk of stomach contents entering your lungs while you are unconscious.
General anaesthesia is intended to keep you unconscious and prevent awareness of the surgical procedure. Your anaesthesia team may use several medicines together to provide appropriate anaesthesia and pain control during surgery.
Rarely, halothane can cause serious liver injury, sometimes called halothane hepatitis. Severe liver reactions can occur even after a first exposure, particularly in adults, although previous exposure to halothane can increase the risk. Tell your doctor about liver problems or previous reactions to anaesthesia.
You will usually begin waking within a relatively short period after the anaesthetic is stopped, but recovery time varies depending on the amount and duration of anaesthesia, other medicines used, the procedure, and your individual response. Your anaesthesia team can explain what to expect for your procedure.
Nausea and vomiting can occur after general anaesthesia. Your healthcare team will assess your risk and may give anti-nausea medicines before, during, or after surgery to help prevent or treat these symptoms.
Malignant hyperthermia is a rare but serious inherited reaction to certain anaesthetic medicines, including halothane. It can cause muscle rigidity, a rapid rise in body temperature, and other dangerous changes. Tell your anaesthetist if you or a family member has had malignant hyperthermia or a serious unexplained reaction to anaesthesia.
Tell your anaesthetist about all medicines and supplements you use, allergies, previous reactions to anaesthesia, and your medical conditions. In particular, mention liver disease, heart or heart rhythm problems, pheochromocytoma, thyroid disease, myasthenia gravis, and any personal or family history of malignant hyperthermia.
Halothane has historically been used in children, but newer inhaled anaesthetics are commonly preferred in many healthcare settings today. A paediatric anaesthesia specialist will choose the most appropriate anaesthetic based on the child's health, procedure, and available options.
Do not drive or operate machinery until your healthcare team says it is safe. General anaesthesia and other medicines used during surgery can temporarily affect alertness, coordination, judgement, and reaction time. Follow the discharge instructions provided by your healthcare team.

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Country of origin

India

Manufacturer/Marketer address

140, Damji Samji Industrial Complex, Mahakali Caves Rd., Andheri(East), Mumbai-93.
Other Info - HYP0125
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