What happen if I miss a dose of Hydrogem Capsules ?

Take the Hydrogem Capsules as soon as you can, but avoid the missed dose if it is nearly time for your next dose. Do not take two doses at one time. Get your prescription refilled before you run out of Hydrogem Capsules entirely.

What happen if I take overdose of Hydrogem Capsules ?

Immediately go to the emergency department of your nearest hospital. Be ready to tell or show what was taken, how much, and when it happened.

What should I avoid while taking this Hydrogem Capsules ?

Hydrogem Capsules may cause a risk of skin cancer. Avoid contact with sunlight or tanning beds. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outside. Do not handle Hydrogem Capsules without the protection of skin.

Can I feel dizziness with this Hydrogem Capsules ?

Hydrogem Capsules can cause dizziness and drowsiness during the first limited hours after you take it. These side effects are more expected to happen when you start taking Hydrogem Capsules or when your doctor increases your dose.

Can I stop taking Hydrogem Capsules if I feel some side effects?

Do not stop taking Hydrogem Capsules without discussing it with your doctor. Your doctor will most likely tell you to take another medicine, folic acid (a vitamin), to reduce some of the side effects of this Hydrogem Capsules . Take this Hydrogem Capsules exactly as instructed.

How many Hydrogem Capsules can I take in a day?

Hydrogem Capsules is a medication that requires careful monitoring and dosing based on your individual medical condition, weight, and other factors. Please consult your healthcare provider if you have any questions about your hydroxyurea dosage. They can provide personal guidance and ensure you're taking the correct amount.

How can you get relief from diarrhoea while on treatment with Hydrogem Capsules ?

Hydrogem Capsules can cause diarrhoea as a side effect. If you have watery or bloody diarrhoea, call your doctor. Do not use anti-diarrhea medicine unless your paediatrician tells you to.

Should I avoid any food and drinks while taking Hydrogem Capsules ?

Yes, it is recommended that you avoid certain foods and drinks while taking Hydrogem Capsules . Some substances can interact with the medication, potentially affecting its effectiveness or increasing the risk of side effects. Here are some things to avoid: alcohol, grapefruit, grapefruit juice, Foods high in tyramine (aged cheeses, cured meats, fermented foods, and certain types of beans), and excessive caffeine.

How do you cope with tiredness and weakness after starting treatment?

If you're feeling tired and weak while taking hydroxyurea, try these tips: rest when needed, eat healthy foods, drink plenty of water, and get enough sleep. Gentle exercise can also help. Discuss with your healthcare provider if you're experiencing severe fatigue or weakness that interferes with your daily activities. They may be able to adjust your treatment or recommend additional strategies.

Does Hydrogem Capsules cause hair loss?

Hydrogem Capsules can make your hair thin or fall out. This is a common side effect, but how much hair you lose can change from person to person. Sometimes, hair loss is temporary, but in rare cases, it can be permanent. If you're worried about hair loss, talk to your doctor. They can help you manage it.

I have noticed some changes in my skin after taking Hydrogem Capsules . What should I do?

If you notice any changes in your skin while taking Hydrogem Capsules , talk to your doctor. It's common to have darker skin or a rash. To protect your skin, use sunscreen, moisturize, and avoid things that might irritate it. If your skin problems are severe, see a dermatologist.

How to relieve constipation during the treatment?

If you are having trouble with constipation while taking Hydrogem Capsules , try these tips: eat more fibre, drink plenty of water, exercise regularly, and consider using over-the-counter laxatives after talking to your doctor. Avoid food that can worsen constipation, and try to go to the bathroom at the same time each day. If your constipation is severe, talk to your doctor.

What precautions should I take to reduce the chances of getting infected during treatment with Hydrogem Capsules ?

To reduce the risk of infection while taking Hydrogem Capsules , wash your hands often, avoid sick people, keep your home clean, get vaccinated, watch for signs of infection, and follow your doctor's instructions.

Hydrogem Capsules 10's

Prescription drug

MRP ₹80

(Inclusive of all Taxes)

₹12.0 Cashback (15%)

Extra 15% Off with Bank Offers

Written By Santoshini Reddy G , M Pharmacy

Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Hydrogem Capsules is used to treat head and neck cancer and sickle cell anaemia (blocking the flow of blood that causes pain and organ damage). It works by blocking an enzyme that is required for growing cells. This prevents the cancer cells from multiplying and growing. In sickle cell disease, it works by increasing fetal haemoglobin (HbF) (haemoglobin of the unborn baby) levels in red blood cells (RBCs). This helps the RBCs accept a normal shape, restores the flow of blood, and protects against problems like painful sickle cell attacks. It may cause side effects such as loss of appetite (feeling unwell and stomach upset), increased bleeding tendency, nausea, upset stomach, and vomiting.

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About Hydrogem Capsules

Hydrogem Capsules is an anticancer medicine used to treat head and neck cancer and sickle cell anaemia (blocking the flow of blood that causes pain and organ damage). Head and neck cancer is a disease including abnormal growth of the tissues of the neck and head that may also have the ability to attack or spread to other portions of the body.

In cancer, Hydrogem Capsules works by blocking an enzyme that is required for growing cells. In sickle cell disease, it works by increasing fetal haemoglobin (HbF) (haemoglobin of the unborn baby) levels in red blood cells (RBCs).

You may experience loss of appetite (feeling unwell and stomach upset), increased bleeding tendency, nausea, upset stomach, and vomiting. Most of these side effects of Hydrogem Capsules do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Take Hydrogem Capsules as prescribed by your doctor. You are advised to take Hydrogem Capsules for as long as your doctor has prescribed it for you, depending on your medical conditions. Do not chew, break, or crush the medicine. Swallow the medicine as a whole with a glass of water.

Before starting Hydrogem Capsules , please inform your doctor if you have any allergies, kidney disease, liver disease, injury to your legs, HIV or AIDS, high levels of uric acid in your blood, or treatment with chemotherapy or radiation. Hydrogem Capsules may increase the chances of other cancer. Inform your doctor about this risk. Immediately contact your doctor if you are pregnant because this Hydrogem Capsules can cause harmful effects on the unborn baby.

Uses of Hydrogem Capsules

Hydrogem Capsules is used in the treatment of head and neck cancer, blood cancer, and sickle cell anaemia. The detailed uses of Hydrogem Capsules are as follows:

Treats Head and Neck Cancer:Hydrogem Capsules is used alone or in combination with radiotherapy to treat squamous cell carcinoma (skin cancer) of the head and neck by preventing the cancer cells from growing and multiplying.
Treats Blood Cancer: Hydrogem Capsules helps slow the progression of chronic myeloid leukaemia by reducing the number of abnormal white blood cells in the bone marrow and blood.
Manages Ovarian Cancer: Hydrogem Capsules is used as part of a chemotherapy treatment to help control the growth and spread of ovarian cancer cells.
Manages Sickle Cell Anaemia: Hydrogem Capsules increases the level of fetal haemoglobin, which helps reduce the frequency of painful sickle cell attacks, the need for blood transfusion, and complications such as acute chest syndrome.

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Directions for Use

Take Hydrogem Capsules with or without food as advised by your doctor.
Hydrogem Capsules is generally taken once a day or as directed by the doctor.
Swallow Hydrogem Capsules as a whole with a glass of water.
Do not chew, crush, or break it.

Medicinal Benefits

Hydrogem Capsules belongs to a group of the class known as an antimetabolite.
It is used to treat head and neck cancer and sickle cell anaemia (blocking the flow of blood that causes pain and organ damage).
In cancer, Hydrogem Capsules works by blocking an enzyme that is required for growing cells. This prevents the cancer cells from multiplying and growing.
In sickle cell disease, it works by increasing fetal haemoglobin (HbF) (haemoglobin of the unborn baby) levels in red blood cells (RBCs).
This helps the RBCs assume a normal shape, restores blood flow, and protects against problems like painful sickle cell attacks.

How Hydrogem Capsules Works

Hydrogem Capsules works by blocking an enzyme required for cell growth. This prevents the cancer cells from multiplying and growing. In sickle cell disease, it works by increasing fetal haemoglobin (HbF) (haemoglobin of the unborn baby) levels in red blood cells (RBCs). This helps the RBCs assume a normal shape, restores blood flow, and protects against problems like painful sickle cell attacks.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Hydrogem Capsules

Do not take more than the prescribed dose of Hydrogem Capsules as it may cause an overdose. The symptoms of overdose include darkening of the skin, sores in the mouth and throat and pain, redness, swelling, and scaling on the hands and feet. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Before taking Hydrogem Capsules inform your doctor if you have any kind of infection because Hydrogem Capsules may worsen the infections.
Consult your doctor if you experience any allergy symptoms.
Inform your doctor if you have any history of kidney disease, liver disease, injury to your legs, HIV or AIDS, high levels of uric acid in your blood, or treatment with chemotherapy or radiation.
Hydrogem Capsules may increase the chances of other cancers. Inform your doctor about this risk.
Immediately contact your doctor if you are pregnant because this Hydrogem Capsules can cause harmful effects on the unborn baby.
Both women and men using this Hydrogem Capsules should use birth control to avoid pregnancy.
The use of this Hydrogem Capsules by either parent may result in birth defects.
You should not take this Hydrogem Capsules during breastfeeding; inform your doctor if you take Hydrogem Capsules .
If any powder from a damaged pill is leaked, wash it up immediately with a wet paper towel and dispose of the towel in a closed plastic bag out of reach of children.

Drug-Drug Interactions

HydroxycarbamideProcaine

Severe

HydroxycarbamideThalidomide

Severe

Drug-Drug Interactions

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HydroxycarbamideProcaine

Severe

How does the drug interact with Hydrogem Capsules:
Procaine has the potential to cause methemoglobinemia (a rare disorder in which the iron in the haemoglobin molecule (the red blood pigment) is defective, preventing it from carrying oxygen to the tissues adequately). This risk increases when used with Hydrogem Capsules, which may lead to methemoglobinemia. When taking these drugs, those who are extremely young (particularly newborns and babies), have heart or lung conditions, certain genetic predispositions, or have a glucose-6-phosphate dehydrogenase deficiencies may be more likely to develop methemoglobinemia.

How to manage the interaction:
Although taking Hydrogem Capsules and procaine together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as grey discolouration of the skin, abnormal blood colouration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.

HydroxycarbamideThalidomide

Severe

How does the drug interact with Hydrogem Capsules:
Taking thalidomide with Hydrogem Capsules may increase the risk of blood clots.

How to manage the interaction:
Although taking thalidomide and Hydrogem Capsules together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, and/or pain, redness or swelling in an arm or leg, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.

HydroxycarbamideLeflunomide

Severe

How does the drug interact with Hydrogem Capsules:
Hydrogem Capsules when used with leflunomide may raise the risk of severe infections.

How to manage the interaction:
There may be a possibility of interaction between Hydrogem Capsules with leflunomide, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhoea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not stop using any medications without a doctor's advice.

HydroxycarbamideVoclosporin

Severe

How does the drug interact with Hydrogem Capsules:
Hydrogem Capsules when used with voclosporin may raise the risk of severe infections, some kinds of cancer, including skin cancer and cancer of the lymph glands (lymphoma).

How to manage the interaction:
There may be a possibility of interaction between Hydrogem Capsules with voclosporin, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhoea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not stop using any medications without a doctor's advice.

HydroxycarbamideDeferiprone

Severe

How does the drug interact with Hydrogem Capsules:
Deferiprone can reduce white blood cell count, and taking it with other medications that might similarly influence white blood cell count or bone marrow function may raise the risk. As a result, you may be more susceptible to get serious infections.

How to manage the interaction:
Co-administration of Hydrogem Capsules with deferiprone can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhoea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.

HydroxycarbamideEtanercept

Severe

How does the drug interact with Hydrogem Capsules:
Hydrogem Capsules when used in conjunction with etanercept may raise the risk of severe infections.

How to manage the interaction:
There may be a possibility of interaction between Hydrogem Capsules with etanercept, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not stop using any medications without a doctor's advice.

HydroxycarbamideMepivacaine

Severe

How does the drug interact with Hydrogem Capsules:
Mepivacaine has the potential to cause methemoglobinemia (a rare disorder in which the iron in the haemoglobin molecule (the red blood pigment) is defective, preventing it from carrying oxygen to the tissues adequately). This risk increases when used with Hydrogem Capsules, which may lead to methemoglobinemia. When taking these drugs, those who are extremely young (particularly newborns and babies), have heart or lung conditions, certain genetic predispositions, or have a glucose-6-phosphate dehydrogenase deficiencies may be more likely to develop methemoglobinemia.

How to manage the interaction:
Although taking Hydrogem Capsules and mepivacaine together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as grey discolouration of the skin, abnormal blood colouration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.

HydroxycarbamideDidanosine

Severe

How does the drug interact with Hydrogem Capsules:
Combining Hydrogem Capsules with didanosine can have serious consequences on your liver or pancreas. Didanosine may potentially induce lactic acidosis (lactic acid buildup in the body).Lactic acidosis can develop gradually and worsen over time.

How to manage the interaction:
Co-administration of Hydrogem Capsules with didanosine can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you have any of the following symptoms while taking didanosine: strong discomfort in your upper stomach that spreads to your back, rapid heart rate, nausea and vomiting, diarrhoea, lack of appetite, low fever, dark urine, clay-colored faeces, or jaundice (yellowing of the skin or eyes), unusual muscle pain and weakness, trouble breathing, fast or uneven heart rate, stomach pain, and numbness or cold feeling in your arms or legs, contact the doctor immediately.

HydroxycarbamideAdalimumab

Severe

How does the drug interact with Hydrogem Capsules:
Hydrogem Capsules when used with Adalimumab may raise the risk of severe infections.

How to manage the interaction:
There may be a possibility of interaction between Hydrogem Capsules with adalimumab, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhoea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not stop using any medications without a doctor's advice.

HydroxycarbamideCertolizumab

Severe

How does the drug interact with Hydrogem Capsules:
Hydrogem Capsules when used with certolizumab may raise the risk of severe infections.

How to manage the interaction:
There may be a possibility of interaction between Hydrogem Capsules with certolizumab, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhoea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Take Hydrogem Capsules at the same time daily, either with or without a meal.
It is recommended to remain hydrated and drink a lot of fluids while taking Hydrogem Capsules .
Do not miss any dose and finish the course as recommended by your doctor.
Use an efficient method of birth control to prevent pregnancy while taking this Hydrogem Capsules .
Your doctor may get routine blood tests done to monitor your liver function, electrolyte levels, and blood cell count.

Habit Forming

No

Therapeutic Class

ANTIMETABOLITES

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Alcohol

Consult your doctor

The drinking of alcohol (in small amounts) does not appear to affect the safety or usefulness of Hydrogem Capsules . Taking alcohol in larger amounts causes dizziness.

Pregnancy

Unsafe

Hydrogem Capsules is not safe during pregnancy because it may cause harmful effects to the baby.

Breast Feeding

Consult your doctor

It is unknown whether Hydrogem Capsules is excreted in human milk. Please consult a doctor before using Hydrogem Capsules while breastfeeding.

Driving

Caution

Hydrogem Capsules may cause dizziness or a severe headache. Therefore, drive only if you are alert after taking Hydrogem Capsules .

Liver

Consult your doctor

If you have any concerns regarding the use of Hydrogem Capsules in patients with liver problems, please consult a doctor.

Kidney

Consult your doctor

If you have any concerns regarding the use of Hydrogem Capsules in patients with kidney problems, please consult a doctor.

Children

Unsafe

The safety and efficacy of Hydrogem Capsules have not been established in children. Therefore, it is not recommended for children.

Heart

Consult your doctor

Please inform your doctor if you have any pre-existing heart problems

Geriatrics

Consult your doctor

Limited information available for use of Hydrogem Capsules in elderly patients. Please consult your doctor.

FAQs

Country of origin

INDIA

Manufacturer/Marketer address

140, Damji Samji Industrial Complex, Mahakali Caves Rd., Andheri(East), Mumbai-93.

Other Info - HYD0082

Author Details

Written By

Santoshini Reddy G

M Pharmacy

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Dec 3, 2025 | 7:35 AM IST

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