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  3. Hopace H 5 Capsule 10's

Prescription drug
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Hopace H 5 Capsule 10's, Pack of 10
Hopace H 5 Capsule 10's, Pack of 10
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Extra 15% Off with Bank Offers

Composition :

HYDROCHLOROTHIAZIDE-12.5MG + RAMIPRIL-5MG

Manufacturer/Marketer :

Micro Labs Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Hopace H 5 Capsule

Hopace H 5 Capsule is used to treat blood pressure. Hypertension (High blood pressure) is a condition in which the force exerted by the blood against the artery walls becomes so high that it causes health problems, such as heart disease.

Hopace H 5 Capsule contains Ramipril and Hydrochlorothiazide. Ramipril relaxes the blood vessels and improves blood flow. Hydrochlorothiazide works by increasing the amount of urine passed out from the kidneys.

Sometimes, you may experience headaches, tiredness, a slow heart rate, and nausea. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Do not take Hopace H 5 Capsule if you are allergic to any of its components. Hopace H 5 Capsule is not recommended in pregnancy and lactation. Keep your doctor informed about your health condition and medications to prevent any interactions.

Uses of Hopace H 5 Capsule

Hopace H 5 Capsule is used in the treatment of Hypertension (high blood pressure). The detailed uses of Hopace H 5 Capsule are as follows:

  • Hypertension (High Blood Pressure): Hopace H 5 Capsule controls blood pressure when single-drug therapy isn’t enough.
  • Prevention of Cardiovascular Events: Hopace H 5 Capsule lowers risk of heart attack, stroke, and heart failure.

Have a query?

Directions for Use

  • Take Hopace H 5 Capsule with or without food as advised by your doctor.
  • It is advised to take Hopace H 5 Capsule once daily in the morning; however, follow your doctor’s recommendation regarding the dosage and duration.
  • Swallow Hopace H 5 Capsule as a whole with a glass of water.
  • Do not crush, chew, or break it.

Medicinal Benefits

  • Hopace H 5 Capsule contains Ramipril and Hydrochlorothiazide, which lower and maintain healthy blood pressure levels.
  • By controlling hypertension, it helps prevent serious cardiovascular events such as heart attack, stroke, and heart failure.
  • Ramipril, an ACE inhibitor, blocks the production of angiotensin II, which relaxes and widens blood vessels to improve blood flow.
  • Hydrochlorothiazide acts as a diuretic, increasing urine output to remove extra salt and water from the body, thereby reducing fluid retention (oedema).
  • By lowering both blood pressure and fluid buildup, Hopace H 5 Capsule helps the heart pump blood more efficiently.
  • It helps relieve swelling associated with heart, liver, kidney, or lung disorders by reducing excess fluid accumulation.
  • The combined action of both ingredients maintains optimal circulation and prevents strain on the heart and arteries.

How Hopace H 5 Capsule Works

Hopace H 5 Capsule contains two medicines: Ramipril (blood pressure-lowering agent) and Hydrochlorothiazide (diuretic or water pill). Ramipril is an angiotensin-converting enzyme or ACE inhibitor that lowers high blood pressure by blocking a naturally occurring substance known as angiotensin II (which tightens your blood vessels). It allows these constricted blood vessels to relax and, therefore, helps lower high blood pressure. On the other hand, Hydrochlorothiazide (diuretic) works by increasing the amount of urine passed out from the kidneys. It effectively reduces excess fluid overload in the body and treats oedema (swelling) associated with heart, liver, kidney, or lung disease. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, both help lower high blood pressure and reduce the chances of heart attacks or strokes.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Hopace H 5 Capsule
Managing Low Blood Pressure Triggered by Medication: Expert Advice:
  • If you experience low blood pressure symptoms like dizziness, lightheadedness, or fainting while taking medication, seek immediate medical attention.
  • Make lifestyle modifications and adjust your medication regimen under medical guidance to manage low blood pressure.
  • As your doctor advises, regularly check your blood pressure at home. Record your readings to detect any changes and share them with your doctor.
  • Fluid intake plays a vital role in managing blood pressure by maintaining blood volume, regulating blood pressure, and supporting blood vessel function. Drinking enough fluids helps prevent dehydration, maintain electrolyte balance, and regulate fluid balance.
  • Take regular breaks to sit or lie down if you need to stand for long periods.
  • When lying down, elevate your head with extra pillows to help improve blood flow.
  • Avoid heavy exercise or strenuous activities that can worsen low blood pressure.
  • Wear compression socks as your doctor advises to enhance blood flow, reduce oedema, and control blood pressure.
  • If symptoms persist or worsen, or if you have concerns about your condition, seek medical attention for personalized guidance and care.
Here are the steps to manage the medication-triggered Cough:
  • Tell your doctor about the cough symptoms you're experiencing, which may be triggered by your medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your cough symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids, such as water, tea, or soup, to help thin out mucus and soothe your throat.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your cough persists or worsens, consult your doctor for further guidance.
  • Confusion is a major psychotic disorder that needs immediate medical attention.
  • Acknowledge your experience and put effort to control confusion.
  • Avoid smoking and alcohol intake as it can worsen the condition and increase your confusion.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes.
  • Talk to your dietician and consume food that can improve your mental health.
  • Always wear loose-fitting clothes which are suitable for your activity.
  • Include the diet containing fruits like watermelon, grapes, bananas and green leafy vegetables.
  • Drink plenty of water stay hydrated.
  • Avoid moving more and staying in hot sun.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

What if I have taken an overdose of Hopace H 5 Capsule

An overdose of Hopace H 5 Capsule may cause unpleasant side effects. If you suspect you have taken an overdose, please consult a doctor immediately.

Drug Warnings

  • Do not take Hopace H 5 Capsule if you are allergic to any of its components, or if you have low blood pressure (hypotension), cardiogenic shock (sudden stopping of blood flow to the heart), anuria (patients with nil urine output), or aortic stenosis (heart valve problem).
  • Inform your doctor if you have had a heart attack, diabetes, kidney disease or liver disease
  • Consult your doctor if you are pregnant, planning to get pregnant or breastfeeding.
  • Do not consume alcohol with Hopace H 5 Capsule as it may increase the risk of low blood pressure.
  • Avoid potassium supplements with Hopace H 5 Capsule as they may lead to high potassium levels in the blood
  • Let your doctor know if you are taking any other medicines, including supplements or herbal products.

Drug-Drug Interactions

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RamiprilAliskiren
Critical
HydrochlorothiazideDofetilide
Critical

Drug-Drug Interactions

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RamiprilAliskiren
Critical
How does the drug interact with Hopace H 5 Capsule:
Taking aliskiren together with Hopace H 5 Capsule may increase the risk of serious side effects such as kidney problems, low blood pressure, and high potassium levels in the blood. High levels of potassium can develop into a condition known as hyperkalemia, which in severe cases can lead to kidney problems, muscle paralysis and irregular heart rhythm.

How to manage the interaction:
Taking Hopace H 5 Capsule with Aliskiren is not recommended, but can be taken if prescribed by a doctor. However, consult your doctor if you feel nausea, vomiting, weakness, confusion, tingling in the hands and feet, a sensation of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat. You must drink enough fluids while taking these medications. It is advised to reduce the intake of foods high in potassium, including tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes. Do not discontinue any medications without a doctor's advice.
HydrochlorothiazideDofetilide
Critical
How does the drug interact with Hopace H 5 Capsule:
Taking Dofetilide and Hopace H 5 Capsule can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Combining Dofetilide and Hopace H 5 Capsule together is not recommended as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
HydrochlorothiazideCisapride
Critical
How does the drug interact with Hopace H 5 Capsule:
Taking Cisapride and Hopace H 5 Capsule can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Combining Cisapride and Hopace H 5 Capsule together is generally avoided as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, or fast or pounding heartbeats, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
RamiprilTrimethoprim
Severe
How does the drug interact with Hopace H 5 Capsule:
Taking Hopace H 5 Capsule with Trimethoprim can increase the potassium levels in the blood, increasing the risk of kidney problems.

How to manage the interaction:
Although there is an interaction between Hopace H 5 Capsule and trimethoprim, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience weakness, confusion, numbness or tingling, and uneven heartbeats. Do not stop taking any medication without consulting your doctor.
RamiprilLeflunomide
Severe
How does the drug interact with Hopace H 5 Capsule:
Taking leflunomide with Hopace H 5 Capsule can increase the risk of liver problems.

How to manage the interaction:
Although taking Hopace H 5 Capsule with Leflunomide can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
RamiprilSpironolactone
Severe
How does the drug interact with Hopace H 5 Capsule:
Using Hopace H 5 Capsule together with spironolactone may cause hyperkalemia (increase the levels of potassium in your blood).

How to manage the interaction:
Although taking spironolactone and captopril together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as weakness, confusion, numbness or tingling, and uneven heartbeat. Do not stop using any medications without consulting doctor.
RamiprilPotassium iodide
Severe
How does the drug interact with Hopace H 5 Capsule:
Taking Potassium Iodide with Hopace H 5 Capsule may significantly increase potassium levels in the blood. High levels of potassium can develop into a condition known as hyperkalemia, which in severe cases can lead to kidney problems, muscle paralysis and irregular heart rhythm.

How to manage the interaction:
Although there is a interaction between Potassium iodide and Hopace H 5 Capsule, you can take these medicines together if prescribed by a doctor. However, if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat, you should contact a doctor immediately. Avoid taking a potassium-rich diet (tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes) while taking these medications. Do not stop using any medications without talking to a doctor.
RamiprilAzilsartan medoxomil
Severe
How does the drug interact with Hopace H 5 Capsule:
Taking Azilsartan medoxomil with Hopace H 5 Capsule may cause low blood pressure, kidney function impairment, and increased potassium levels in the blood.

How to manage the interaction:
Although taking Hopace H 5 Capsule together with Azilsartan medoxomil can result in an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience vomiting, weakness, confusion, tingling in the hands and feet, or palpitations. Do not discontinue any medications without a doctor's advice.
RamiprilCandesartan
Severe
How does the drug interact with Hopace H 5 Capsule:
Taking Hopace H 5 Capsule with Candesartan may increase the risk of side effects such as low blood pressure, kidney function impairment, and a condition called hyperkalemia (high blood potassium).

How to manage the interaction:
Although taking Hopace H 5 Capsule together with Candesartan can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, consult your doctor if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat You must drink enough fluids while taking these medications. Do not stop taking any medication without consulting your doctor.
RamiprilLosartan
Severe
How does the drug interact with Hopace H 5 Capsule:
Coadministration of Hopace H 5 Capsule together with losartan may increase the risk of side effects such as low blood pressure, kidney function impairment, and a condition called hyperkalemia (high blood potassium).

How to manage the interaction:
Taking Losartan with Hopace H 5 Capsule together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat, you should contact a doctor immediately. Avoid taking a potassium-rich diet (tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes) while taking these medications. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Keep your weight under control with a body mass index (BMI) of 19.5-24.9.
  • Do regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week. Doing this can help lower your raised blood pressure by about 5 mm Hg.
  • Opt for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.
  • Limit sodium chloride (table salt) intake in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.
  • If you are taking alcohol, then only one serving for women and two servings is advisable.
  • Quitting smoking is the best strategy to lower the risk of heart disease.
  • Avoid chronic stress, as it can raise your blood pressure. Try to enjoy and spend time with your loved ones to cope with stress and practice mindfulness techniques.
  • Monitor your blood pressure daily, and if there is too much fluctuation, immediately contact your doctor.
  • Including heart-healthy omega-3 fatty acid acid-containing foods in your daily diet.
  • Use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil to lower your elevated blood pressure.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

Hopace H 5 Capsule Substitute

Substitutes safety advice
bannner image

Alcohol

Caution

Hopace H 5 Capsule may enhance the hypotensive (low blood pressure) effect if alcohol is taken along with it. For better advice, you should consult your doctor about whether you can take Hopace H 5 Capsule with alcohol.

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Pregnancy

Unsafe

The use of Hopace H 5 Capsule or any ACE inhibitors (Ramipril) is usually contraindicated during the second and third trimesters of pregnancy. It may cause harm to the developing fetus. Hence, you should always consult your doctor before using Hopace H 5 Capsule .

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Breast Feeding

Caution

Use of Hopace H 5 Capsule is not recommended during the breastfeeding stage.

bannner image

Driving

Caution

Drive with caution, Hopace H 5 Capsule may cause blurry vision, and dizziness or weariness may occur.

bannner image

Liver

Caution

Rare elevation in the liver enzymes (like bilirubin) has been observed while taking Hopace H 5 Capsule , so it must be taken with caution. If you have a history of liver diseases/conditions, the dose may have to be adjusted by your doctor.

bannner image

Kidney

Caution

Hopace H 5 Capsule to be taken with caution, especially in case of severe kidney disease. The dose may have to be adjusted by your doctor. Hopace H 5 Capsule should be given with precaution in hemodialysis conditions.

bannner image

Children

Caution

Hopace H 5 Capsule is not recommended for children. The safety and effectiveness of Hopace H 5 Capsule have not been established in children due to limited testing of this drug on children by competent authorities worldwide. If necessary, your doctor will decide whether to give Hopace H 5 Capsule or not.

FAQs

Hopace H 5 Capsule is used to treat hypertension (high blood pressure).

Hopace H 5 Capsule contains Ramipril (blood pressure-lowering agent) and Hydrochlorothiazide (diuretic or water pill). Ramipril is an angiotensin-converting enzyme or ACE inhibitor that lowers high blood pressure by blocking a naturally occurring substance known as angiotensin II (which tightens your blood vessels). It allows these constricted blood vessels to relax and, therefore, helps lower high blood pressure. On the other hand, Hydrochlorothiazide works by increasing the amount of urine passed out from the kidneys. It effectively reduces excess fluid overload in the body and treats oedema (swelling) associated with heart, liver, kidney, or lung disease. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, both help lower high blood pressure and reduce the chances of heart attacks or strokes.

Yes, Hopace H 5 Capsule can cause dizziness. It is advised to avoid driving or operating any heavy machinery while taking Hopace H 5 Capsule . In case you feel dizzy or lightheaded, it is recommended to rest for some time until you feel better.

It is advised to continue your medicine even after your blood pressure is under control or becomes normal, as blood pressure can shoot up at any time. If you have any discomfort, please consult your doctor immediately.

If you forget to take Hopace H 5 Capsule at any time, take it as soon as you remember, then continue to take it at the usual times. Do not take a double dose to make up for a forgotten dose.

No, it is a prescribed drug given by a physician to prevent specific medical conditions. Taking it on your own can cause unwanted side effects.

Yes, in some cases, Hopace H 5 Capsule may affect your serum potassium level, so consult your doctor before using potassium supplements or its salt substitutes.

Hopace H 5 Capsule should not be used if you have a history of a serious allergic reaction, including swelling of the face/lips/tongue/throat (angioedema) and an inability to pass urine. Before going outdoor in the sun, try to wear sunscreen (SPF) and avoid sunlamps and tanning booths as prolonged intake of Hopace H 5 Capsule may cause your skin to be sensitive to the sunlight.

Yes, if you have diabetes, Hopace H 5 Capsule may change your blood sugar level, so check your blood sugar regularly as directed. Tell your doctor if you have high blood sugar (hyperglycemia) symptoms like increased thirst/urination or signs of low blood sugar (hypoglycemia) such as sudden sweating, shaking, fast heartbeat, hunger, blurred vision, dizziness, or tingling hands/feet. Your doctor might adjust your dose of Hopace H 5 Capsule .

The common side effects of Hopace H 5 Capsule include headaches, tiredness, slow heart rate, and nausea. Most of these side effects gradually resolve over time; however, if they persist, please inform your doctor.

No, you should not stop treatment with Hopace H 5 Capsule even if you feel an improvement in your symptoms because high blood pressure often has no symptoms and can shoot up at any time. Continue taking it for as long as it has been advised by your doctor.

Yes, you can take Hopace H 5 Capsule every day if advised by the doctor. Just make sure to follow your doctor’s instructions regarding how long to use it. Taking it for years on your own without your doctor’s approval could be fatal.

Country of origin

India

Manufacturer/Marketer address

No. 28 Sundar Industrial Estate,N.T.Y Layout Mysore Road , Bangalore - 560026, India
Other Info - HOP0004

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Oct 16, 2025 | 12:25 PM IST

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Reference

  1. https://www.healthline.com/health/ramipril-oral-capsule
  2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/019901s060lbl.pdf
  3. https://www.nhs.uk/medicines/ramipril/
  4. https://www.sps.nhs.uk/articles/safety-in-lactation-diuretics/
  5. https://www.drugs.com/tips/hydrochlorothiazide-patient-tips

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