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  3. Hepmend Granules 5gm

Hepmend Granules 5gm, Pack of 1 Tablet
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Hepmend Granules 5gm is used to treat liver diseases. It contains L-ornithine-L-aspartate, which effectively prevents multiple liver disease mechanisms and ensures the protection, regeneration, and rejuvenation of the liver. This medicine may sometimes cause side effects such as headache, fatigue, diarrhoea, abdominal pain, and nausea. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Composition :

L ORNITHINE L ASPARTATE-3GM

Manufacturer/Marketer :

Emcure Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Hepmend Granules 5gm

Hepmend Granules 5gm is used to treat liver diseases such as acute and chronic hepatitis, chronic alcoholic liver damage, fatty liver, jaundice, liver cirrhosis, and non-alcoholic steatohepatitis (non-alcoholic fatty liver disease).

Hepmend Granules 5gm contains L-ornithine-L-aspartate, which rejuvenates the liver by increasing the rate of energy production in liver cells and decreasing ammonia levels in the blood by increasing ammonia detoxification.

In some cases, Hepmend Granules 5gm may cause side effects, such as headache, fatigue, diarrhoea, abdominal pain, and nausea. Most of these side effects do not require medical attention and will resolve gradually over time. However, consult your doctor if the side effects persist or worsen.

Let your doctor know if you are allergic to any of the contents in Hepmend Granules 5gm. Consult your doctor before taking Hepmend Granules 5gm if you are pregnant or breastfeeding. Keep your doctor informed about your health condition and medications to prevent potential interactions.

Uses of Hepmend Granules 5gm

Hepmend Granules 5gm is used as a supportive treatment in various liver diseases. The detailed uses of Hepmend Granules 5gm are as follows:

  • Manages Hepatic Encephalopathy: Hepmend Granules 5gm helps reduce elevated blood ammonia levels, a major cause of hepatic encephalopathy (a decline in brain function due to severe liver disease), by converting ammonia into urea for safe excretion.
  • Supports Fatty Liver Disease Treatment: Hepmend Granules 5gm helps manage fatty liver by protecting liver cells from damage caused by fat buildup (lipid peroxidation), improving blood flow within the liver, and reducing liver inflammation.
  • Treats Acute and Chronic Hepatitis: Hepmend Granules 5gm helps improve liver function in patients with liver inflammation caused by infections, toxins, or other factors.
  • Manages Chronic Alcoholic Liver Damage: Hepmend Granules 5gm supports liver detoxification and regeneration in individuals with liver damage due to long-term alcohol use.
  • Supports Liver Cirrhosis Treatment: Hepmend Granules 5gm is used as an adjunct therapy in chronic liver conditions such as cirrhosis (permanent scarring of the liver).

Directions for Use

  • Hepmend Granules 5gm can be taken with or without food as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow it as a whole with a glass of water.
  • Do not chew, crush or break it.

Medicinal Benefits

  • Hepmend Granules 5gm helps lower elevated ammonia levels in the bloodstream, which is crucial in managing conditions like hepatic encephalopathy, a condition caused by liver dysfunction leading to the buildup of toxins (especially ammonia) in the brain.
  • It aids the body's natural detox process by facilitating the conversion of ammonia into urea, which is then excreted in urine.
  • It contains amino acids such as ornithine and aspartic acid, which are involved in metabolic processes, particularly the urea cycle.
  • This medicine helps raise levels of arginine, an important amino acid that supports detoxification, immune function, and nitric oxide production.
  • It also offers hepatoprotective (liver-protecting) effects, especially in individuals with fatty liver disease or compromised liver function.
  • Hepmend Granules 5gm helps maintain a healthy nitrogen balance in the body by converting toxic nitrogen waste into less harmful forms.
  • By lowering ammonia levels, it may indirectly improve cognitive symptoms associated with hepatic encephalopathy, such as confusion or lethargy.

How Hepmend Granules 5gm Works

Hepmend Granules 5gm contains L-ornithine-L-aspartate, which rejuvenates the liver by increasing the rate of energy production in liver cells and decreasing ammonia levels in the blood by increasing ammonia detoxification.

Storage

• Store in a cool and dry place away from sunlight.• Keep Hepmend Granules 5gm out of reach and sight of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Hepmend Granules 5gm

Take Hepmend Granules 5gm only as prescribed by the physician. Do not exceed the recommended dose, as it might cause an overdose leading to unpleasant side effects. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

  • Do not take Hepmend Granules 5gm if you are allergic to any of its components.
  • Consult your doctor before taking Hepmend Granules 5gm if you are pregnant or breastfeeding.
  • Be cautious while driving and operating machinery, as it is unknown if Hepmend Granules 5gm interferes with your ability to drive.
  • Avoid consuming alcohol along with Hepmend Granules 5gm as it could lead to further liver damage.
  • Hepmend Granules 5gm should not be given to children unless prescribed by the doctor.
  • Inform your doctor about your health condition and the medicines you take to rule out any side effects/interactions.

Drug-Drug Interactions

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No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid alcohol consumption and quit smoking.
  • Maintain a healthy weight by exercising regularly.
  • Adopt a liver-friendly diet, including fibre-rich food.
  • Cut down on fats, sugar, and salt.
  • Avoid stress by practising yoga or meditation.
  • Exercise regularly, as it helps in reducing the accumulation of fat.

Habit Forming

No

Therapeutic Class

HEPATOPROTECTIVE AGENTS

Hepmend Granules 5gm Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Hepmend Granules 5gm as it may lead to further liver damage.

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Pregnancy

Consult your doctor

Limited information is available regarding the use of Hepmend Granules 5gm during pregnancy. Consult your doctor before taking Hepmend Granules 5gm if you are pregnant or if you have any concerns; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

Limited information is available regarding the usage of Hepmend Granules 5gm in breastfeeding mothers. Consult your doctor before taking Hepmend Granules 5gm; your doctor will decide whether Hepmend Granules 5gm can be taken by breastfeeding mothers or not.

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Driving

Caution

It is not known if Hepmend Granules 5gm interferes with your ability to drive. Be cautious while driving or operating machinery.

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Liver

Safe if prescribed

Hepmend Granules 5gm is used to treat various liver diseases. So, it is probably safe to be taken by patients with liver impairment. However, consult your doctor if you have any concerns.

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Kidney

Consult your doctor

Please consult your doctor if you have any concerns regarding the usage of Hepmend Granules 5gm in patients with kidney impairment.

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Children

Consult your doctor

Limited information is available regarding the usage of Hepmend Granules 5gm in children. Please consult your doctor.

Have a query?

FAQs

Hepmend Granules 5gm is used to treat liver diseases such as acute and chronic hepatitis, chronic alcoholic liver damage, fatty liver, jaundice, liver cirrhosis, and non-alcoholic steatohepatitis (non-alcoholic fatty liver disease).

Hepmend Granules 5gm rejuvenates the liver by increasing the rate of energy production in liver cells. It decreases ammonia levels in the blood by increasing ammonia detoxification. Â Hepmend Granules 5gm helps in treating liver disease.

Do not discontinue Hepmend Granules 5gm without consulting your doctor. To treat your condition effectually, continue taking Hepmend Granules 5gm for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Hepmend Granules 5gm.

Consult your doctor before taking levodopa with Hepmend Granules 5gm, as it might lower the efficacy of levodopa.

Diarrhoea could be a side-effect of Hepmend Granules 5gm. Drink plenty of fluids and eat non-spicy food if you experience diarrhoea. Consult your doctor if you have severe diarrhoea or if you find blood in your stools.

Hepmend Granules 5gm effectively prevents multiple liver diseases and ensures protection, regeneration, and rejuvenation of the liver. Thereby, treats liver disease and helps in the proper functioning of the liver.

Country of origin

India

Manufacturer/Marketer address

255/2, Hinjawadi, Pune - 411057, India
Other Info - HEP0267

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Aug 5, 2025 | 7:18 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.cochrane.org/CD012410/LIVER_l-ornithine-l-aspartate-people-chronic-liver-disease-and-hepatic-encephalopathy-poor-brain
  2. https://pubmed.ncbi.nlm.nih.gov/20642112/
  3. https://core.ac.uk/download/pdf/47262911.pdf

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