Hepcinat Plus Tablet 28's

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Hepcinat Plus Tablet 28's

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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Hepcinat Plus Tablet 28's is an antiviral medicine used to treat chronic HCV (Hepatitis C virus) infection. It contains Daclatasvir and Sofosbuvir. This medicine works by blocking a key protein and enzyme in the hepatitis C virus, preventing the virus from making copies of itself and assembling new virus particles. This helps stop the spread of the virus in the body. In some cases, this medication may cause common side effects such as nausea, diarrhoea, abdominal pain, difficulty sleeping, dizziness, tiredness, headache, insomnia (sleeplessness), and joint or muscle pain. Before taking Hepcinat Plus Tablet 28's, inform your doctor if you have any allergies, are pregnant or breastfeeding, are taking any other medications, or have any pre-existing medical conditions.

Composition :

DACLATASVIR-60MG + SOFOSBUVIR-400MG

Manufacturer/Marketer :

Natco Pharma Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Hepcinat Plus Tablet 28's

Hepcinat Plus Tablet 28's belongs to a class of drugs called antivirals. It is used to treat chronic HCV (Hepatitis C virus) infection. Hepatitis C is a viral infection that causes inflammation or swelling in the liver, which can lead to severe liver damage. It is caused by the hepatitis C virus (HCV) and spreads through contact when infected blood enters the bloodstream of someone who is not infected.

Hepcinat Plus Tablet 28's contains antiviral drugs daclatasvir and sofosbuvir reduce the amount of the virus in the body, which is how they treat chronic hepatitis C (HCV). They function by preventing the activity of two proteins that are necessary for the virus to replicate.

Hepcinat Plus Tablet 28's should be taken in the dose and duration prescribed by the doctor. In some cases, Hepcinat Plus Tablet 28's may cause common side effects such as nausea, diarrhoea, abdominal pain, difficulty sleeping, dizziness, tiredness, headache, insomnia (sleeplessness), and joint or muscle pain. Typically, these side effects do not require medical attention and will subside independently. However, if they persist or become more severe, please consult your doctor.

Please inform your doctor if you are allergic to any of the ingredients in Hepcinat Plus Tablet 28's or taking any other medications. Avoid using Hepcinat Plus Tablet 28's if you are pregnant or planning to become pregnant and are not using birth control. Both you and your partner should use effective birth control methods during treatment and for 5 weeks after finishing the medication. If you become pregnant during treatment, contact your doctor immediately. Hepcinat Plus Tablet 28's is not recommended for use in children below 18 years of age, as its efficacy and safety have not been established in this age group. Also, inform your doctor if you have any pre-existing conditions, such as diabetes, hepatitis B, a history of liver transplant, heart or kidney problems, or HIV (human immunodeficiency virus) infection, before starting Hepcinat Plus Tablet 28's.

Uses of Hepcinat Plus Tablet 28's

Hepcinat Plus Tablet 28's is used in the treatment of chronic Hepatitis C virus infection. The detailed uses of Hepcinat Plus Tablet 28's are as follows:

Chronic Hepatitis C virus infection treatment:Hepcinat Plus Tablet 28's targets and inhibits viral replication proteins to treat chronic Hepatitis C virus (HCV) infection.
Liver Protection:Hepcinat Plus Tablet 28's guards against serious liver damage and lowers inflammation in the liver.

Have a query?

Directions for Use

Hepcinat Plus Tablet 28's can be taken with or without food or as advised by your doctor.
Follow your doctor's instructions on the dosage and timing of this medication.
Swallow Hepcinat Plus Tablet 28's as a whole with a glass of water.
Do not break, crush, or open it.

Medicinal Benefits

Hepcinat Plus Tablet 28's belongs to a class of drugs called 'antivirals,' primarily used to treat chronic HCV (Hepatitis C virus) infection, particularly genotype 3. It contains antiviral drugs daclatasvir and sofosbuvir, which reduce the amount of the virus in the body, which is how they treat chronic hepatitis C (HCV). They function by preventing the activity of two proteins that are necessary for the virus to replicate.

How Hepcinat Plus Tablet 28's Works

Hepcinat Plus Tablet 28's contains antiviral drugs daclatasvir and sofosbuvir, which reduce the amount of the virus in the body, which is how they treat chronic hepatitis C (HCV). They function by preventing the activity of two proteins that are necessary for the virus to replicate.

Storage

• Store in a cool and dry place away from sunlight.• Keep it out of sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Hepcinat Plus Tablet 28's

Do not exceed the prescribed dose, as it may lead to an overdose, resulting in serious side effects or poisoning. If you suspect you have taken an overdose or notice any unusual symptoms, seek medical attention from a doctor or visit a nearby hospital.

Drug Warnings

Please inform your doctor if you are allergic to any ingredients in Hepcinat Plus Tablet 28's or if you are taking any other medications, including prescription and over-the-counter (OTC) drugs, vitamins, or herbal supplements. If you are taking Hepcinat Plus Tablet 28's along with amiodarone (a medication for irregular heartbeats), you may need regular heart monitoring, as it could excessively slow your heart rate (severe bradycardia). Avoid using Hepcinat Plus Tablet 28's if you are pregnant or planning to become pregnant and are not using birth control. Both you and your partner should use effective birth control methods during treatment and for 5 weeks after finishing the medication. If you become pregnant during treatment, contact your doctor immediately. Hepcinat Plus Tablet 28's is not recommended for use in children below 18 years of age, as its efficacy and safety have not been established in this age group. If you are infected with hepatitis C, take the necessary precautions to prevent spreading the infection to others. Before starting treatment, you should be tested for current and past hepatitis B (HBV) infections, as HBV reactivation can occur in people with both HCV and HBV, especially if treated for HCV but not HBV. Additionally, inform your doctor if you have any pre-existing conditions, such as diabetes, hepatitis B, a history of liver transplant, heart or kidney problems, or HIV (human immunodeficiency virus) infection, before starting Hepcinat Plus Tablet 28's.

Drug-Drug Interactions

DaclatasvirCarbamazepine

Critical

DaclatasvirPrimidone

Critical

Drug-Drug Interactions

DaclatasvirCarbamazepine

Critical

How does the drug interact with Hepcinat Plus Tab:
When Hepcinat Plus Tab is taken with Carbamazepine, it may decrease the blood levels of Hepcinat Plus Tab, which may make Hepcinat Plus Tab less effective in treating your Hepatitis C.

How to manage the interaction:
Taking Hepcinat Plus Tab with Carbamazepine is not recommended, but it can be taken if prescribed by the doctor. However, if you experience any unusual symptoms, consult the doctor. Do not discontinue any medications without a doctor's advice.

DaclatasvirPrimidone

Critical

How does the drug interact with Hepcinat Plus Tab:
Coadministration of Hepcinat Plus Tab with primidone may decrease the blood levels of Hepcinat Plus Tab, which may make the medication less effective in treating the condition.

How to manage the interaction:
Although there is an interaction between Primidone and Hepcinat Plus Tab, they can be taken together if advised by your doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

SofosbuvirModafinil

Severe

How does the drug interact with Hepcinat Plus Tab:
Coadministration of Hepcinat Plus Tab with Modafinil may significantly reduce the blood levels of Hepcinat Plus Tab.

How to manage the interaction:
Co-administration of Modafinil with Hepcinat Plus Tab can possibly result in an interaction, but it can be taken if your doctor has advised it. If you're having symptoms of stomach pain or swelling, Fatigue, Fever, Yellowing of skin or eyes, Dark urine, loss of appetite, or nausea contact your doctor right away. Do not discontinue any medications without first consulting your doctor.

SofosbuvirPhenobarbital

Severe

How does the drug interact with Hepcinat Plus Tab:
Phenobarbital can drastically lower Hepcinat Plus Tab levels in the blood, making the medicine less effective.

How to manage the interaction:
Although taking phenobarbital with Hepcinat Plus Tab can lead to interaction, they can be taken if recommended by a doctor. Do not stop using any medications without consulting a doctor.

SofosbuvirCarbamazepine

Severe

How does the drug interact with Hepcinat Plus Tab:
Taking carbamazepine and Hepcinat Plus Tab together may possibly reduce the effects of Hepcinat Plus Tab, which may make the medication less effective.

How to manage the interaction:
Although taking carbamazepine and Hepcinat Plus Tab together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.

SofosbuvirPhenytoin

Severe

How does the drug interact with Hepcinat Plus Tab:
Using Hepcinat Plus Tab together with phenytoin may significantly reduce the blood levels of Hepcinat Plus Tab.

How to manage the interaction:
Although there is a possible interaction between Hepcinat Plus Tab and Phenytoin, you can take these medicines together if prescribed by a doctor. Doctors can recommend other options that won't cause any problems when taken together. Do not stop using any medications without a doctor's advice.

SofosbuvirRifabutin

Severe

How does the drug interact with Hepcinat Plus Tab:
Taking Rifabutin and Hepcinat Plus Tab may significantly reduce the blood levels of Hepcinat Plus Tab, which may make the medication less effective.

How to manage the interaction:
Taking Hepcinat Plus Tab with Rifabutin together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

SofosbuvirOxcarbazepine

Severe

How does the drug interact with Hepcinat Plus Tab:
Oxcarbazepine can drastically lower Hepcinat Plus Tab levels in the blood, making the medicine less effective in treating.

How to manage the interaction:
Although taking oxcarbazepine with Hepcinat Plus Tab can lead to interaction, they can be taken if recommended by a doctor. Do not stop using any medications without talking to a doctor.

DaclatasvirBosentan

Severe

How does the drug interact with Hepcinat Plus Tab:
Bosentan can lower the levels of Hepcinat Plus Tab in your blood, which could decrease its effectiveness in treating your condition.

How to manage the interaction:
Although using Bosentan and Hepcinat Plus Tab together can possibly result in an interaction, they can be taken together if advised by your doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.

DaclatasvirColchicine

Severe

How does the drug interact with Hepcinat Plus Tab:
Coadministration of colchicine with Hepcinat Plus Tab may increase the blood levels of colchicine, increasing the risk of side effects.

How to manage the interaction:
Although taking Colchicine and Hepcinat Plus Tab together may possibly result in an interaction, they can be taken together if prescribed by your doctor. However, if you experience nausea, vomiting, abdominal pain, numbness or tingling in your hands and legs, muscle pain, or weakness, contact your doctor immediately. Do not discontinue any medication without consulting your doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

Diet & Lifestyle Advise

Maintain a healthy weight through diet and exercise to support liver health.
Avoid smoking and alcohol consumption to reduce the risk of liver damage.
Consider getting vaccinated for hepatitis A and B to protect your liver health.
Follow a balanced diet rich in fruits, vegetables, fibre, and protein; avoid excessive fats and processed foods.
Monitor salt and protein intake if liver damage is severe, with guidance from your doctor or dietitian.
Avoid sharing personal items like razors or toothbrushes to prevent the spreading of hepatitis C.
Clean wounds and surfaces with household bleach to reduce transmission risks.
Use condoms during sex, especially during sex with new partners, to lower the risk of transmission.
Consult your doctor before travelling abroad to ensure necessary precautions and medication storage for hepatitis C.
Pregnancy is possible with hepatitis C, but discuss with your doctor to understand the risks and medications' effects on pregnancy.

Habit Forming

Therapeutic Class

ANTIVIRALS

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Alcohol

Consult your doctor

It is not known if Hepcinat Plus Tablet 28's interacts with alcohol. Please consult your doctor.

Pregnancy

Unsafe

Hepcinat Plus Tablet 28's should not be taken by pregnant women or by women of reproductive age who are not taking contraception. For five weeks following the completion of treatment with Hepcinat Plus Tablet 28's, the use of highly effective contraception should be maintained.

Breast Feeding

Caution

It is unknown whether Hepcinat Plus Tablet 28's passes into breast milk. Therefore, you should avoid breastfeeding while undergoing treatment with Hepcinat Plus Tablet 28's. Please consult your doctor for advice.

Driving

Caution

Hepcinat Plus Tablet 28's may cause dizziness. Do not drive or operate heavy machinery if you are not fully alert.

Liver

Caution

Hepcinat Plus Tablet 28's does not need to be dosage adjusted for patients with mild, moderate, or severe liver impairment. In patients with decompensated cirrhosis, the safety and effectiveness of this medicine have not been proven.

Kidney

Caution

It is not necessary to change the dosage of Hepcinat Plus Tablet 28's for patients with mild to moderate kidney impairment. In patients with end-stage kidney disease (ESRD) requiring hemodialysis or severe renal impairment (estimated glomerular filtration rate [eGFR] <30 mL/min/1.73 m2), the safety and dosage of sofosbuvir have not been determined.

Children

Unsafe

Hepcinat Plus Tablet 28's is not recommended for use in children below 18 years of age, as its efficacy and safety have not been established in this age group.

Heart

Hepcinat Plus Tablet 28's is generally considered safe for patients with heart problems. Consult your doctor if you have any concerns regarding it.

Geriatrics

Safe if prescribed

Hepcinat Plus Tablet 28's is generally safe for geriatric individuals. Please consult your doctor if you have any concerns.

FAQs

What is the use of Hepcinat Plus Tablet 28's?

Hepcinat Plus Tablet 28's belongs to a class of drugs called antivirals. It is used to treat chronic Hepatitis C virus (HCV) infection.

How does Hepcinat Plus Tablet 28's work?

Are there any side effects of Hepcinat Plus Tablet 28's?

Hepcinat Plus Tablet 28's may cause common side effects, such as nausea, diarrhoea, abdominal pain, difficulty sleeping, dizziness, tiredness, headache, insomnia (sleeplessness), and joint or muscle pain in some cases. These side effects are usually mild and tend to go away on their own without requiring medical treatment. However, if they persist or become more severe, please consult your doctor.

Is hepatitis C virus infection contagious?

Yes, hepatitis C virus (HCV) infection is contagious and can spread through contact with the blood of an infected person. To reduce the risk of spreading the virus, it is advised not to share personal items or needles that may have come into contact with an infected individual's blood.

Does Hepcinat Plus Tablet 28's cure Hepatitis C?

Hepcinat Plus Tablet 28's is an antiviral drug that can successfully treat Hepatitis C. However, the effectiveness of the treatment varies depending on factors such as the specific type of Hepatitis C, the degree of liver damage, any other existing health conditions, and how well the patient responds to the medication. It is essential to follow your doctor's instructions closely and keep up with regular check-ups during and after treatment to increase the chances of a successful cure.

Is it safe to use Hepcinat Plus Tablet 28's if I am being treated with amiodarone for an irregular heartbeat?

You should be cautious when using Hepcinat Plus Tablet 28's if you are currently taking or have taken amiodarone in the past few months. Contact your doctor immediately if you experience symptoms of a slow heartbeat, such as chest pain, dizziness, fainting, confusion, memory issues, fatigue, weakness, or shortness of breath. If Hepcinat Plus Tablet 28's treatment is necessary, you may need additional heart monitoring.

Can I use Hepcinat Plus Tablet 28's if I am pregnant?

No, do not use Hepcinat Plus Tablet 28's if you are pregnant or planning to become pregnant and are not using birth control. Both you and your partner should use effective birth control methods during treatment and for 5 weeks after finishing the medication. If you become pregnant during treatment, contact your doctor immediately.

Country of origin

India

Manufacturer/Marketer address

Natco House, Road No.2, Banjara Hills, Hyderabad-500 034, India

Other Info - HEP0303

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