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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Heparex Injection 5 ml is used to prevent and treat deep vein thrombosis (blood clots in leg veins), pulmonary embolism (blood clots in the lung), stroke, Transient ischaemic attack (TIA), and heart attacks. It contains Heparin, which works by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot), preventing blood clot formation. Some people may experience haemorrhage (bleeding), thrombocytopenia (low platelets), hypersensitivity reactions, and elevations of liver enzyme (aminotransferase) levels. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Whats That

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Composition :

HEPARIN-5000IU

Manufacturer/Marketer :

Sai Parenterals Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Heparex Injection 5 ml

Heparex Injection 5 ml belongs to a class of drugs called anticoagulants or blood thinners. Heparex Injection 5 ml is primarily used to prevent and treat deep vein thrombosis (blood clots in leg veins), pulmonary embolism (blood clots in the lung), stroke, Transient ischaemic attack (TIA), and heart attacks. Deep vein thrombosis is a medical condition in which blood clots form in deep veins, usually in the legs. Pulmonary embolism is a condition in which a blood clot blocks the arteries in the lungs. A stroke is a condition where a blood clot restricts the flow of blood to your brain, causing brain cells to die and possibly resulting in permanent brain damage or death. Transient ischaemic attack (TIA) is a condition also called mini-strokes. These have similar symptoms to a stroke, but the effects usually last less than 24 hours. Heart attack is a condition where a blood clot blocks a blood vessel supplying your heart, starving it of oxygen and causing chest pain and sometimes death.

Blood clots are formed to stop bleeding that occurs due to tissue injury. Though blood clots are useful to stop bleeding, they may be harmful when abnormally formed within blood vessels as they block blood vessels and inhibit blood flow to essential organs such as the brain, heart, or lungs. Heparex Injection 5 ml works by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot), preventing blood clot formation.

Heparex Injection 5 ml will be administered by a healthcare professional; do not self-administer. Some people may experience haemorrhage, thrombocytopenia (low platelets), hypersensitivity reactions, and elevations of liver enzyme (aminotransferase) levels. Most of these side effects of Heparex Injection 5 ml do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Heparex Injection 5 ml or any other medicines, please tell your doctor. It is not known whether Heparex Injection 5 ml harms the baby or passes into breast milk in pregnancy and breastfeeding state. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Heparex Injection 5 ml. Heparex Injection 5 ml is not recommended for children below 2 months of age. If you have diabetes, kidney or liver problems, bleeding problems, or are aged above 60 years, inform your doctor before taking Heparex Injection 5 ml.

Uses of Heparex Injection 5 ml

Heparex Injection 5 ml is used in the prevention of blood clots. The detailed uses of Heparex Injection 5 ml are as follows:<br/>• Prevent and treat blood clots: Heparex Injection 5 ml helps to prevent and dissolve blood clots in conditions such as deep vein thrombosis (DVT), pulmonary embolism, and during certain medical procedures.<br/>• Anticoagulation therapy: Heparex Injection 5 ml is often used as an anticoagulant to reduce the risk of blood clot formation and stroke.<br/>

Directions for Use

• Your doctor will determine the dosage and timing of Heparex Injection 5 ml based on your medical condition and response to treatment.• Heparex Injection 5 ml is administered by a qualified healthcare professional in a medical setting.• Do not self-administer it.

Medicinal Benefits

Heparex Injection 5 ml is primarily used to prevent and treat blood clots by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot). Heparex Injection 5 ml also reduces the risk of blood clots during surgeries (like heart surgery). Heparex Injection 5 ml is used as an anticoagulant in blood transfusion and in a dialysis procedure.

How Heparex Injection 5 ml Works

Heparex Injection 5 ml works by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot), preventing blood clot formation.

Storage

Keep Heparex Injection 5 ml out of the sight and reach of children.

What if I have taken an overdose of Heparex Injection 5 ml

The overdose of Heparex Injection 5 ml is unlikely as it is administered by a doctor. Too much heparin may cause bleeding. Therefore, if you suspect any adverse reactions or unusual symptoms or more severe bleeding while on treatment with Heparex Injection 5 ml, please inform your doctor immediately.

Drug Warnings

Use Heparex Injection 5 ml cautiously in conditions with increased risk of bleeding. Use of name contraindicated in patients with HIT - Heparin-induced thrombosis (the abnormal formation of blood clots inside a blood vessel) and HITT (heparin-induced thrombocytopenia and thrombosis) might occur. Monitoring of blood coagulation tests like platelet count and haematocrit should be done in all patients receiving Heparex Injection 5 ml. Patients should inform the doctor that they are receiving Heparex Injection 5 ml before any surgery is scheduled.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Heparex Injection 5 ml:
Taking Ticlopidine with Heparex Injection 5 ml can increase the risk of bleeding.

How to manage the interaction:
Taking Ticlopidine with Heparex Injection 5 ml is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Heparex Injection 5 ml:
Taking Tenecteplase with Heparex Injection 5 ml can increase the risk of bleeding.

How to manage the interaction:
Taking Heparex Injection 5 ml with Tenecteplase is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you notice unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Heparex Injection 5 ml:
Taking Alteplase with Heparex Injection 5 ml can increase the risk of bleeding.

How to manage the interaction:
Taking Heparex Injection 5 ml with Alteplase is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you have unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
HeparinOritavancin
Critical
How does the drug interact with Heparex Injection 5 ml:
Using Heparex Injection 5 ml with Oritavancin can make Heparex Injection 5 ml less effective as a therapy.

How to manage the interaction:
Heparex Injection 5 ml is not recommended within 120 hours (5 days) of taking oritavancin. Oritavancin can interfere with certain of the major coagulation tests used to assess Heparex Injection 5 ml's effectiveness and safety, it can be taken only if prescribed by a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Heparex Injection 5 ml:
Taking Mifepristone with Heparex Injection 5 ml can increase the risk of negative side effects.

How to manage the interaction:
Taking Heparex Injection 5 ml with Mifepristone is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
HeparinBazedoxifene
Critical
How does the drug interact with Heparex Injection 5 ml:
When Heparex Injection 5 ml is taken with bazedoxifene the effects of Heparex Injection 5 ml are reduced by bazedoxifene.

How to manage the interaction:
Taking Bazedoxifene with Heparex Injection 5 ml is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Heparex Injection 5 ml:
Taking Dasatinib with Heparex Injection 5 ml can increase the risk and severity of bleeding.

How to manage the interaction:
Although there is a possible interaction between Heparex Injection 5 ml and Dasatinib, you can take these medicines together if prescribed by a doctor. However, consult a doctor, if you experience bruising, dizziness, red or black, tarry stools, severe headache, and weakness. Do not stop using any medications without a doctor's advice.
How does the drug interact with Heparex Injection 5 ml:
Sulfadiazine enhances the effects of Heparex Injection 5 ml by slowing its breakdown.

How to manage the interaction:
Co-administration of Sulfadiazine with Heparex Injection 5 ml can result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without talking to a doctor.
How does the drug interact with Heparex Injection 5 ml:
Taking Heparex Injection 5 ml with Urokinase can increase the risk of bleeding.

How to manage the interaction:
Co-administration of Heparex Injection 5 ml with Urokinase can result in an interaction, but it can be taken if a doctor has advised it. However, if you have unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Heparex Injection 5 ml:
Coadministration of Heparex Injection 5 ml and Apixaban co-administration may raise the risk of bleeding.

How to manage the interaction:
Even though combining Heparex Injection 5 ml and Apixaban may cause an interaction, it is still possible to take it if a doctor advises you to. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Without consulting a doctor, never stop taking any medications.

Drug-Food Interactions

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HEPARIN-5000IUHerbal products/medicines
Moderate

Drug-Food Interactions

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HEPARIN-5000IUHerbal products/medicines
Moderate
Common Foods to Avoid:
Garlic Pill

How to manage the interaction:
Taking Heparex Injection 5 ml along with herbs and supplements such as garlic, ginger, bilberry, danshen, piracetam, and ginkgo biloba can lead to an increased risk of bleeding Avoid taking herbs and supplements such as garlic, ginger, bilberry, danshen, piracetam, and ginkgo biloba while taking Heparex Injection 5 ml.

Habit Forming

No

Therapeutic Class

ANTICOAGULANTS / ANTITHROMBOTICS. ANTICONVULSANTS
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Alcohol

Caution

You are recommended to avoid consumption of alcohol with Heparex Injection 5 ml as it may cause severe bleeding in the stomach and harmful side effects to the liver.

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Pregnancy

Caution

Heparex Injection 5 ml is a Category C pregnancy drug and should be given to pregnant women only if clearly needed and has more benefits than risks. Preservative-free forms are preferred in pregnant women as preservatives such as benzyl alcohol may cross the placenta.

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Breast Feeding

Caution

Heparex Injection 5 ml should be given to breastfeeding mothers only if clearly needed and has more benefits than risks.

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Driving

Safe if prescribed

Heparex Injection 5 ml usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Heparex Injection 5 ml should be given with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Heparex Injection 5 ml should be given with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Heparex Injection 5 ml is not recommended for children below 2 months.

Have a query?

FAQs

Heparex Injection 5 ml is used to prevent and treat deep vein thrombosis (blood clots in leg veins), pulmonary embolism (blood clots in the lung), stroke, Transient ischaemic attack (TIA), and heart attacks.

Heparex Injection 5 ml works by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot). Thereby, preventing blood clot formation.

No, you are not recommended to take ibuprofen with Heparex Injection 5 ml as co-administration of these two medicines may increase the risk of bleeding more easily. However, please consult a doctor before taking other medicines with Heparex Injection 5 ml.

Yes, Heparex Injection 5 ml may increase potassium levels in the blood (hyperkalaemia), especially when given for a long period. Therefore, it is advised to inform your doctor if you are taking any medicines that increase potassium levels in the blood.

Yes, Heparex Injection 5 ml may cause bleeding. If you notice purple spots on the skin or unusual bruising, blood in urine, black tarry stools, unusual bleeding from gums or nose, please inform your doctor immediately as these are signs of bleeding more easily.

Yes, Heparex Injection 5 ml may cause allergic reactions such as fever, chills, difficulty in breathing, wheezing, blue shade to the lips, swelling of lips, and eyes. It is not necessary for everyone taking Heparex Injection 5 ml to experience an allergic reaction. However, if you notice any of these signs, please inform your doctor immediately.

Country of origin

India

Manufacturer/Marketer address

Plot No-39, 4th Floor, Lavanya Arcade, Jayabheri Enclave, Gachibowli, Hyderabad 500 032, Telangana State, India
Other Info - HEP0362

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