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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Hep 25 Injection is used to prevent and treat deep vein thrombosis (blood clots in leg veins), pulmonary embolism (blood clots in the lung), stroke, Transient ischaemic attack (TIA), and heart attacks. It contains Heparin, which works by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot), preventing blood clot formation. Some people may experience haemorrhage (bleeding), thrombocytopenia (low platelets), hypersensitivity reactions, and elevations of liver enzyme (aminotransferase) levels. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition :

HEPARIN-25000IU

Manufacturer/Marketer :

Gland Pharma Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

About Hep 25 Injection

Hep 25 Injection belongs to a class of drugs called anticoagulants or blood thinners. Hep 25 Injection is primarily used to prevent and treat deep vein thrombosis (blood clots in leg veins), pulmonary embolism (blood clots in the lung), stroke, Transient ischaemic attack (TIA), and heart attacks. Deep vein thrombosis is a medical condition in which blood clots form in deep veins, usually in the legs. Pulmonary embolism is a condition in which a blood clot blocks the arteries in the lungs. A stroke is a condition where a blood clot restricts the flow of blood to your brain, causing brain cells to die and possibly resulting in permanent brain damage or death. Transient ischaemic attack (TIA) is a condition also called mini-strokes. These have similar symptoms to a stroke, but the effects usually last less than 24 hours. Heart attack is a condition where a blood clot blocks a blood vessel supplying your heart, starving it of oxygen and causing chest pain and sometimes death.

Blood clots are formed to stop bleeding that occurs due to tissue injury. Though blood clots are useful to stop bleeding, they may be harmful when abnormally formed within blood vessels as they block blood vessels and inhibit blood flow to essential organs such as the brain, heart, or lungs. Hep 25 Injection works by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot), preventing blood clot formation.

Hep 25 Injection will be administered by a healthcare professional; do not self-administer. Some people may experience haemorrhage, thrombocytopenia (low platelets), hypersensitivity reactions, and elevations of liver enzyme (aminotransferase) levels. Most of these side effects of Hep 25 Injection do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Hep 25 Injection or any other medicines, please tell your doctor. It is not known whether Hep 25 Injection harms the baby or passes into breast milk in pregnancy and breastfeeding state. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Hep 25 Injection. Hep 25 Injection is not recommended for children below 2 months of age. If you have diabetes, kidney or liver problems, bleeding problems, or are aged above 60 years, inform your doctor before taking Hep 25 Injection.

Uses of Hep 25 Injection

Hep 25 Injection is used in the prevention of blood clots. The detailed uses of Hep 25 Injection are as follows:<br/>• Prevent and treat blood clots: Hep 25 Injection helps to prevent and dissolve blood clots in conditions such as deep vein thrombosis (DVT), pulmonary embolism, and during certain medical procedures.<br/>• Anticoagulation therapy: Hep 25 Injection is often used as an anticoagulant to reduce the risk of blood clot formation and stroke.<br/>

Directions for Use

• Your doctor will determine the dosage and timing of Hep 25 Injection based on your medical condition and response to treatment.• Hep 25 Injection is administered by a qualified healthcare professional in a medical setting.• Do not self-administer it.

Medicinal Benefits

Hep 25 Injection is primarily used to prevent and treat blood clots by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot). Hep 25 Injection also reduces the risk of blood clots during surgeries (like heart surgery). Hep 25 Injection is used as an anticoagulant in blood transfusion and in a dialysis procedure.

How Hep 25 Injection Works

Hep 25 Injection works by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot), preventing blood clot formation.

Storage

Keep Hep 25 Injection out of the sight and reach of children.
Side effects of Hep 25 Injection
  • Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
  • Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
  • Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
  • Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
  • If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
  • In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
  • Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
  • If you experience severe bleeding or bruising, seek emergency medical attention immediately.

What if I have taken an overdose of Hep 25 Injection

The overdose of Hep 25 Injection is unlikely as it is administered by a doctor. Too much heparin may cause bleeding. Therefore, if you suspect any adverse reactions or unusual symptoms or more severe bleeding while on treatment with Hep 25 Injection, please inform your doctor immediately.

Drug Warnings

Use Hep 25 Injection cautiously in conditions with increased risk of bleeding. Use of name contraindicated in patients with HIT - Heparin-induced thrombosis (the abnormal formation of blood clots inside a blood vessel) and HITT (heparin-induced thrombocytopenia and thrombosis) might occur. Monitoring of blood coagulation tests like platelet count and haematocrit should be done in all patients receiving Hep 25 Injection. Patients should inform the doctor that they are receiving Hep 25 Injection before any surgery is scheduled.

Drug-Drug Interactions

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HeparinOritavancin
Critical
HeparinBazedoxifene
Critical

Drug-Drug Interactions

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HeparinOritavancin
Critical
How does the drug interact with Hep 25 Injection:
Using Hep 25 Injection with Oritavancin can make Hep 25 Injection less effective as a therapy.

How to manage the interaction:
Hep 25 Injection is not recommended within 120 hours (5 days) of taking oritavancin. Oritavancin can interfere with certain of the major coagulation tests used to assess Hep 25 Injection's effectiveness and safety, it can be taken only if prescribed by a doctor. Do not discontinue any medications without a doctor's advice.
HeparinBazedoxifene
Critical
How does the drug interact with Hep 25 Injection:
When Hep 25 Injection is taken with bazedoxifene the effects of Hep 25 Injection are reduced by bazedoxifene.

How to manage the interaction:
Taking Bazedoxifene with Hep 25 Injection is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Hep 25 Injection:
Taking Alteplase with Hep 25 Injection can increase the risk of bleeding.

How to manage the interaction:
Taking Hep 25 Injection with Alteplase is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you have unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Hep 25 Injection:
Taking Mifepristone with Hep 25 Injection can increase the risk of negative side effects.

How to manage the interaction:
Taking Hep 25 Injection with Mifepristone is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Hep 25 Injection:
Taking Tenecteplase with Hep 25 Injection can increase the risk of bleeding.

How to manage the interaction:
Taking Hep 25 Injection with Tenecteplase is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you notice unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Hep 25 Injection:
Taking Ticlopidine with Hep 25 Injection can increase the risk of bleeding.

How to manage the interaction:
Taking Ticlopidine with Hep 25 Injection is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Hep 25 Injection:
Taking Hep 25 Injection with Deferasirox can increase the risk of gastrointestinal bleeding and ulcer.

How to manage the interaction:
Taking Deferasirox with Hep 25 Injection together can result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor, if you experience stomach pain, bloating, dizziness, lightheadedness, loss of hunger, nausea, vomiting (especially with fresh or dried blood that looks like coffee grounds), and red or black, tarry stools. Do not stop taking any medications without consulting a doctor.
How does the drug interact with Hep 25 Injection:
Taking cefdinir with Hep 25 Injection may enhance the effects of Hep 25 Injection by anticoagulation(preventing blood from clotting).

How to manage the interaction:
Although taking Cefdinir and Hep 25 Injection can cause an interaction, it can be taken if a doctor has suggested it. In case you experience aby unusual effects like lightheadedness, dizziness, unusual bruising, bleeding tendencies, blood in stools or urine, consult a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Hep 25 Injection:
Taking Bivalirudin with Hep 25 Injection may increase the risk of bleeding.

How to manage the interaction:
Although taking Bivalirudin and Hep 25 Injection together can cause an interaction, it can be taken if a doctor has suggested it. However, if you have unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Hep 25 Injection:
Coadministration of Ketorolac with Hep 25 Injection can increase the risk of bleeding.

How to manage the interaction:
There may be a possibility of interaction between Ketorolac and Hep 25 Injection, but it can be taken if prescribed by a doctor. However, if you experience any unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, call a doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

ANTICOAGULANTS / ANTITHROMBOTICS. ANTICONVULSANTS
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Alcohol

Caution

You are recommended to avoid consumption of alcohol with Hep 25 Injection as it may cause severe bleeding in the stomach and harmful side effects to the liver.

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Pregnancy

Caution

Hep 25 Injection is a Category C pregnancy drug and should be given to pregnant women only if clearly needed and has more benefits than risks. Preservative-free forms are preferred in pregnant women as preservatives such as benzyl alcohol may cross the placenta.

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Breast Feeding

Caution

Hep 25 Injection should be given to breastfeeding mothers only if clearly needed and has more benefits than risks.

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Driving

Safe if prescribed

Hep 25 Injection usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Hep 25 Injection should be given with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Hep 25 Injection should be given with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Hep 25 Injection is not recommended for children below 2 months.

Have a query?

FAQs

Hep 25 Injection is used to prevent and treat deep vein thrombosis (blood clots in leg veins), pulmonary embolism (blood clots in the lung), stroke, Transient ischaemic attack (TIA), and heart attacks.

Hep 25 Injection works by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot). Thereby, preventing blood clot formation.

No, you are not recommended to take ibuprofen with Hep 25 Injection as co-administration of these two medicines may increase the risk of bleeding more easily. However, please consult a doctor before taking other medicines with Hep 25 Injection.

Yes, Hep 25 Injection may increase potassium levels in the blood (hyperkalaemia), especially when given for a long period. Therefore, it is advised to inform your doctor if you are taking any medicines that increase potassium levels in the blood.

Yes, Hep 25 Injection may cause bleeding. If you notice purple spots on the skin or unusual bruising, blood in urine, black tarry stools, unusual bleeding from gums or nose, please inform your doctor immediately as these are signs of bleeding more easily.

Yes, Hep 25 Injection may cause allergic reactions such as fever, chills, difficulty in breathing, wheezing, blue shade to the lips, swelling of lips, and eyes. It is not necessary for everyone taking Hep 25 Injection to experience an allergic reaction. However, if you notice any of these signs, please inform your doctor immediately.

Country of origin

India
Other Info - HEPI304

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