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  3. Hemlibra 30 mg Injection 1's

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Hemlibra 30 mg Injection 1's, Pack of 1 Injection
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Written By ,
Reviewed By Santoshini Reddy G , M Pharmacy

Hemlibra 30 mg Injection is a Monoclonal antibody used to prevent or reduce bleeding episodes in individuals with haemophilia A, a condition caused by a missing or defective blood clotting factor. Hemlibra 30 mg Injection connects activated factor IX and factor X, promoting effective clot formation in individuals with haemophilia A. This process helps prevent and minimize bleeding episodes, including in patients with factor VIII inhibitors. The common side effects may include redness, tenderness, warmth, or itching at the injection site, joint pain and headache.

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Composition :

EMICIZUMAB-30MG

Manufacturer/Marketer :

Roche Diagnostics India Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Hemlibra 30 mg Injection

Hemlibra 30 mg Injection is used to prevent or reduce bleeding episodes in individuals with haemophilia A. Haemophilia A is a genetic bleeding disorder caused by a deficiency or absence of clotting factor VIII that impairs blood clotting ability. It leads to prolonged bleeding episodes, often following injuries or surgeries, and can cause spontaneous internal bleeding.

Hemlibra 30 mg Injection contains Emicizumab, which works by replicating the function of factor VIII, a crucial protein for blood clotting. It connects activated factor IX and factor X, promoting effective clot formation in individuals with haemophilia A. This process helps prevent and minimize bleeding episodes, including in patients with factor VIII inhibitors.

The dose and duration of treatment with Hemlibra 30 mg Injection may vary depending on your medical condition. The common side effects of Hemlibra 30 mg Injection include redness, tenderness, warmth, or itching at the injection site, as well as joint pain and headache. Most of these side effects resolve gradually over time. However, consult the doctor if any of these persist or worsen.

Inform your doctor if you are pregnant or planning pregnancy or breastfeeding before treatment with Hemlibra 30 mg Injection. Hemlibra 30 mg Injection is safe for children if prescribed by the doctor. Avoid alcohol consumption while taking Hemlibra 30 mg Injection to prevent unpleasant side effects. Hemlibra 30 mg Injection may cause dizziness; therefore, avoid driving or operating heavy machinery unless fully alert. Inform your doctor about all the medicines you are taking and about your pre-existing health conditions.

Uses of Hemlibra 30 mg Injection

Hemlibra 30 mg Injection is used to prevent or reduce bleeding episodes in individuals with haemophilia A (a genetic bleeding disorder). The detailed uses of Hemlibra 30 mg Injection are as follows:

  • Treatment of Hemophilia A:Hemlibra 30 mg Injection is used in patients with factor VIII deficiency, reducing the frequency of spontaneous bleeding episodes.
  • Prevention of Bleeding Episodes:Hemlibra 30 mg Injection helps stabilize clot formation, preventing excessive bleeding in hemophilia A patients and reduces the need for frequent factor VIII infusions, improving quality of life.

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Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Hemlibra 30 mg Injection is to be used under medical supervision. With proper training in subcutaneous injection, patients may be allowed to administer it themselves.
  • Hemlibra 30 mg Injection should not be injected into red or bruised areas.

Medicinal Benefits

Hemlibra 30 mg Injection contains Emicizumab, which belongs to a group of medications called Monoclonal antibodies. It is used to prevent or reduce bleeding episodes in individuals with haemophilia A (a genetic bleeding disorder). Hemlibra 30 mg Injection replicates the function of factor VIII, a crucial protein for blood clotting. It connects activated factor IX and factor X, promoting effective clot formation in individuals with haemophilia A. This process helps prevent and minimize bleeding episodes, including in patients with factor VIII inhibitors.

How Hemlibra 30 mg Injection Works

Hemlibra 30 mg Injection contains Emicizumab. It works by replicating the function of factor VIII, a crucial protein for blood clotting. It connects activated factor IX and factor X, promoting effective clot formation in individuals with hemophilia A. This process helps prevent and minimize bleeding episodes, including in patients with factor VIII inhibitors.

Storage

• Store in a cool and dry place away from sunlight.• Keep Hemlibra 30 mg Injection out of reach and sight of children.• Cold chain - To be stored in cold places at 2ºC to 8ºC.
Side effects of Hemlibra 30 mg Injection
  • Injection site reaction can include numbness or redness.
  • Get a physical examination, follow your doctor's instructions, if it worsens or gets swollen.
  • Apply cold compress for pain relief.
  • Practice good hygiene and keep the injection site away from heat and pressure.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the steps to manage Joint Pain caused by medication usage:
  • Please inform your doctor about joint pain symptoms, as they may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Your doctor may prescribe common pain relievers if necessary to treat joint discomfort.
  • Maintaining a healthy lifestyle is key to relieving joint discomfort. Regular exercise, such as low-impact sports like walking, cycling, or swimming, should be combined with a well-balanced diet. Aim for 7-8 hours of sleep per night to assist your body in repairing and rebuilding tissue.
  • Applying heat or cold packs to the affected joint can help reduce pain and inflammation.
  • Please track when joint pain occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • If your joint pain is severe or prolonged, consult a doctor to rule out any underlying disorders that may require treatment.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

What if I have taken an overdose of Hemlibra 30 mg Injection

There is limited experience with Hemlibra 30 mg Injection overdose. However, an accidental overdose could lead to increased blood clotting (hypercoagulability). In such cases, contact the doctor immediately and be closely monitored.

Drug Warnings

Inform your doctor if you are using factor VIII or a bypassing agent, as these may increase the risk of blood clots, particularly when combined with activated prothrombin complex concentrate (aPCC). You may need to stop using bypassing agents or adjust their dosage as instructed by your doctor. Also, inform your doctor about any pre-existing medical conditions and all medications you are taking, including over-the-counter drugs, vitamins, and herbal supplements. Let your doctor know if you are pregnant or planning to become pregnant.

Drug-Drug Interactions

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No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

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Diet & Lifestyle Advise

  • Eat a well-balanced diet by including plenty of fruits, vegetables, lean proteins, and whole grains to support overall health and maintain a healthy weight, which benefits joint health.
  • Stay active by choosing safe exercises to strengthen muscles and joints. This can help reduce the risk of bleeding. Consult a doctor or physical therapist for guidance.
  • Avoid risky activities by avoiding participating in sports or activities with a high risk of injury or bleeding.
  • Avoid alcohol as it may harm liver function and affect blood clotting.

Habit Forming

No

Therapeutic Class

MONOCLONAL ANTIBODIES

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Alcohol

Consult your doctor

The interaction of alcohol with Hemlibra 30 mg Injection is unknown. If you have any concerns, please discuss them with your doctor.

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Pregnancy

Caution

Please inform your doctor if you are pregnant or planning to become pregnant; your doctor will administer Hemlibra 30 mg Injection only if the benefits outweigh the risks. Also, women who are capable of becoming pregnant must use effective contraception during and for a minimum of 6 months after stopping treatment with Hemlibra 30 mg Injection.

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Breast Feeding

Consult your doctor

It is unknown if Hemlibra 30 mg Injection passes into breast milk. Therefore, please inform your doctor if you are breastfeeding. Your doctor decides based on the benefits and risks of Hemlibra 30 mg Injection to the mother and baby.

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Driving

Safe if prescribed

Hemlibra 30 mg Injection usually does not affect your ability to drive or operate machines.

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Liver

Consult your doctor

Please inform your doctor if you have liver impairment/liver disease before receiving Hemlibra 30 mg Injection.

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Kidney

Consult your doctor

Please inform your doctor if you have kidney impairment/kidney disease before receiving Hemlibra 30 mg Injection.

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Children

Safe if prescribed

Hemlibra 30 mg Injection is safe for children if prescribed by a doctor. The dose and duration may vary depending on the child’s weight and the severity of the child's medical condition.

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Heart

Please inform your doctor if you have heart problems before receiving Hemlibra 30 mg Injection, as there is limited information available on its safety in such cases.

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Geriatrics

Safe if prescribed

Hemlibra 30 mg Injection is generally safe for geriatric individuals. Please consult your doctor if you have any concerns.

FAQs

Hemlibra 30 mg Injection belongs to the group of medications called Monoclonal antibodies used to prevent or reduce bleeding episodes in individuals with haemophilia A, a genetic bleeding disorder caused by a clotting factor VIII deficiency.

Hemlibra 30 mg Injection contains Emicizumab. It replicates the function of factor VIII, a crucial protein for blood clotting. It connects activated factor IX and factor X, promoting effective clot formation in individuals with hemophilia A. This process helps prevent and minimize bleeding episodes, including in patients with factor VIII inhibitors.

If you use Hemlibra 30 mg Injection with a bypassing agent and if you experience confusion, weakness, vomiting, stomach or back pain, less urination, chest pain, trouble breathing, coughing blood, fast heartbeat, swelling or redness in your arms or legs, eye pain, or vision issues, contact your doctor immediately.

Hemlibra 30 mg Injection may cause common side effects like redness, tenderness, warmth, or itching at the injection site, joint pain, and headache. However, please consult your doctor if any of these side effects persist or worsen.

Country of origin

India

Manufacturer/Marketer address

Roche Diagnostics India Pvt Ltd, 501 B, Silver Utopia, Cardinal Gracious Road, Chakala Road, Andheri East, Mumbai €“ 400069
Other Info - HEM0275

Disclaimer

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Reference

  1. https://medlineplus.gov/druginfo/meds/a622046.html
  2. https://www.drugs.com/mtm/emicizumab.html
  3. https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/761083s000lbl.pdf
  4. https://www.ema.europa.eu/en/documents/product-information/hemlibra-epar-product-information_en.pdf
  5. https://www.hemlibra.com/side-effects/important-safety-information.html
  6. https://www.accessdata.fda.gov/drugsatfda_docs/nda/2017/761083Orig1s000ChemR.pdf
  7. https://www.medicines.org.uk/emc

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