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compositionComposition:EMICIZUMAB-30MG
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Prescription Medicine
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Hemlibra 30 mg Injection is a Monoclonal antibody used to prevent or reduce bleeding episodes in individuals with haemophilia A, a condition caused by a missing or defective blood clotting factor. Hemlibra 30 mg Injection connects activated factor IX and factor X, promoting effective clot formation in individuals with haemophilia A. This process helps prevent and minimize bleeding episodes, including in patients with factor VIII inhibitors. The common side effects may include redness, tenderness, warmth, or itching at the injection site, joint pain and headache.

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Written By ,
Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Composition :

EMICIZUMAB-30MG

Manufacturer/Marketer :

Roche Diagnostics India Pvt Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Hemlibra 30 mg Injection

This injection is used regularly as a long-term preventive treatment. To get the best results, you must inject it consistently on your scheduled days, even if you do not feel any symptoms of bleeding. While this medicine works internally to help your blood clot, maintaining a healthy weight and staying active can support your joint health.

Most people tolerate this medication well, but you may experience redness, itching, or pain at the injection site, as well as headaches or joint pain. If you experience severe symptoms like sudden pain, swelling in your arms or legs, numbness, or breathing difficulties, you must contact your doctor immediately.

Before starting this medication, tell your healthcare provider if you have any other health conditions or allergies. Do not take this if you have had a severe allergic reaction to this medication or any of its ingredients in the past. Always talk to your doctor or pharmacist to ensure this treatment is safe for your specific health profile.

This medication can interact seriously with certain other clotting therapies, which can increase your risk of developing dangerous blood clots. If you are pregnant, planning to become pregnant, breastfeeding, or are an older adult, talk to your doctor to understand the risks and benefits before starting treatment.

Uses of Hemlibra 30 mg Injection

Your doctor may prescribe Hemlibra 30 mg Injection to help manage the following conditions:

  • Hemophilia A with factor VIII inhibitors: Hemlibra 30 mg Injection helps prevent or reduce the frequency of bleeding episodes in adults and children who have developed antibodies against factor VIII.
  • Hemophilia A without factor VIII inhibitors: Hemlibra 30 mg Injection is used as routine prevention to protect people who do not have factor VIII inhibitors from spontaneous bleeding.

Key Benefits

This medicine helps you manage your condition by providing steady, continuous protection against bleeding episodes. Key benefits of using Hemlibra 30 mg Injection include:

  • Fewer bleeding episodes: It significantly lowers the number of bleeding events in your muscles, joints, and organs, helping you feel more secure in your daily activities.
  • Convenient routine protection: Because it is injected under the skin at regular intervals, it offers a more flexible routine compared to frequent, time-consuming vein infusions of clotting factors.
  • Preserved joint health: Fewer bleeds into your joints mean less long-term joint damage and stiffness, helping you maintain physical mobility and comfort over time.
Side effects of Hemlibra 30 mg Injection
  • Injection site reaction can include numbness or redness.
  • Get a physical examination, follow your doctor's instructions, if it worsens or gets swollen.
  • Apply cold compress for pain relief.
  • Practice good hygiene and keep the injection site away from heat and pressure.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the steps to manage Joint Pain caused by medication usage:
  • Please inform your doctor about joint pain symptoms, as they may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Your doctor may prescribe common pain relievers if necessary to treat joint discomfort.
  • Maintaining a healthy lifestyle is key to relieving joint discomfort. Regular exercise, such as low-impact sports like walking, cycling, or swimming, should be combined with a well-balanced diet. Aim for 7-8 hours of sleep per night to assist your body in repairing and rebuilding tissue.
  • Applying heat or cold packs to the affected joint can help reduce pain and inflammation.
  • Please track when joint pain occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • If your joint pain is severe or prolonged, consult a doctor to rule out any underlying disorders that may require treatment.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Hemlibra 30 mg Injection is to be used under medical supervision. With proper training in subcutaneous injection, patients may be allowed to administer it themselves.
  • Hemlibra 30 mg Injection should not be injected into red or bruised areas.

How Hemlibra 30 mg Injection Works

Hemlibra 30 mg Injection contains emicizumab, a laboratory-made protein known as a monoclonal antibody, designed to replace a missing clotting factor. In a healthy body, clotting factors work together like a chain reaction to stop bleeding. In hemophilia A, the body is missing Factor VIII, which normally binds two other proteins (Factor IX and Factor X) together to help the blood clot. This medicine works by mimicking the action of the missing Factor VIII. It physically bridges Factor IX and Factor X together, restarting the natural clotting process. This helps your blood form stable clots and prevents bleeding, even though your body still lacks the actual Factor VIII.
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Alcohol

Consult your doctor

The interaction of alcohol with Hemlibra 30 mg Injection is unknown. If you have any concerns, please discuss them with your doctor.

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Pregnancy

Caution

Please inform your doctor if you are pregnant or planning to become pregnant; your doctor will administer Hemlibra 30 mg Injection only if the benefits outweigh the risks. Also, women who are capable of becoming pregnant must use effective contraception during and for a minimum of 6 months after stopping treatment with Hemlibra 30 mg Injection.

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Breast Feeding

Consult your doctor

It is unknown if Hemlibra 30 mg Injection passes into breast milk. Therefore, please inform your doctor if you are breastfeeding. Your doctor decides based on the benefits and risks of Hemlibra 30 mg Injection to the mother and baby.

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Driving

Safe if prescribed

Hemlibra 30 mg Injection usually does not affect your ability to drive or operate machines.

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Liver

Consult your doctor

Please inform your doctor if you have liver impairment/liver disease before receiving Hemlibra 30 mg Injection.

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Kidney

Consult your doctor

Please inform your doctor if you have kidney impairment/kidney disease before receiving Hemlibra 30 mg Injection.

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Children

Safe if prescribed

Hemlibra 30 mg Injection is safe for children if prescribed by a doctor. The dose and duration may vary depending on the child’s weight and the severity of the child's medical condition.

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Heart

Caution

Please inform your doctor if you have heart problems before receiving Hemlibra 30 mg Injection, as there is limited information available on its safety in such cases.

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Geriatrics

Safe if prescribed

Hemlibra 30 mg Injection is generally safe for geriatric individuals. Please consult your doctor if you have any concerns.

What if I have taken an overdose of Hemlibra 30 mg Injection

If you inject more than your prescribed dose, seek emergency medical attention. Keep the medication packaging with you so the healthcare providers know exactly what you took.

Diet & Lifestyle Advise

  • Engage in low-impact physical activities: Regular, gentle exercises like swimming, walking, or cycling can strengthen the muscles around your joints without putting them at high risk of injury or bleeding.
  • Maintain a healthy weight: Excess body weight puts extra stress on your weight-bearing joints, which can increase the risk of joint bleeds and long-term wear and tear.
  • Prioritise dental health: Brush and floss regularly to prevent gum disease and bleeding. Inform your dentist that you are using Hemlibra 30 mg Injection before scheduling any dental procedures.
  • Wear protective gear: Always wear helmets, knee pads, or other appropriate safety gear when participating in recreational activities to protect against accidental bumps or falls.
health query

Have a query?

How Soon It Starts Working

The time required for Hemlibra 30 mg Injection to start to work: The exact onset of time for Hemlibra 30 mg Injection is unknown. The time for which the effects of Hemlibra 30 mg Injection last: The duration of Hemlibra 30 mg Injection effect is unknown.

What if you forget to take Hemlibra 30 mg Injection

If you miss a dose, inject it as soon as you remember, provided it is before your next scheduled dose. After that, resume your normal dosing schedule. Do not inject a double dose on the same day to make up for a missed one. If you are unsure what to do, talk to your doctor or pharmacist.

Storage

• Store this medication in a refrigerator between 2°C to 8°C. Do not freeze it, and do not use it if it has been frozen.

Drug Warnings

  • Check the solution before injecting: Inspect the liquid in the vial. It should be clear to slightly yellowish. Do not use it if it is cloudy, contains visible particles, or looks discoloured.
  • Rotate your injection sites: Use a different spot for each injection (stomach, thigh, or upper arm) to keep your skin healthy and reduce irritation.
  • Avoid certain rescue therapies: Talk to your doctor about what rescue medicines to use if you experience a breakthrough bleed. Avoid using activated prothrombin complex concentrate (aPCC) while taking Hemlibra 30 mg Injection unless specifically directed, as this combination can cause dangerous blood clots.
  • Keep a treatment log: Write down the date, time, and injection site for every dose to help track your treatment compliance and share this with your healthcare team.
  • Do not rub the injection site: After injecting, you can press a clean cotton ball or gauze gently on the site if needed, but do not rub it, as this can increase irritation.

Drug-Drug Interactions

verifiedApollotooltip
  • Activated prothrombin complex concentrate (aPCC): Combining this rescue treatment with Hemlibra 30 mg Injection can lead to severe, life-threatening blood clots or damage to small blood vessels. Avoid using these together unless strictly monitored by your specialist.
  • Factor VIII concentrates: While these are generally safer than aPCC to use for breakthrough bleeding, they should still be used cautiously under your doctor’s guidance.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

verifiedApollotooltip

  • No clinically significant food interactions are known with Hemlibra 30 mg Injection when used as directed. 

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[MONOCLONAL ANTIBODIES]

FAQs

Hemlibra 30 mg Injection belongs to the group of medications called Monoclonal antibodies used to prevent or reduce bleeding episodes in individuals with haemophilia A, a genetic bleeding disorder caused by a clotting factor VIII deficiency.
Hemlibra 30 mg Injection contains Emicizumab. It replicates the function of factor VIII, a crucial protein for blood clotting. It connects activated factor IX and factor X, promoting effective clot formation in individuals with hemophilia A. This process helps prevent and minimize bleeding episodes, including in patients with factor VIII inhibitors.
If you use Hemlibra 30 mg Injection with a bypassing agent and if you experience confusion, weakness, vomiting, stomach or back pain, less urination, chest pain, trouble breathing, coughing blood, fast heartbeat, swelling or redness in your arms or legs, eye pain, or vision issues, contact your doctor immediately.
Hemlibra 30 mg Injection may cause common side effects like redness, tenderness, warmth, or itching at the injection site, joint pain, and headache. However, please consult your doctor if any of these side effects persist or worsen.
The frequency depends on your doctor's prescription. It is typically injected once a week, once every two weeks, or once every four weeks. Always follow your doctor's exact instructions.
Yes, you can travel with this medication. You should store it in a travel cooler with ice packs to keep it at the proper refrigerated temperature. Never place it in your checked luggage where it might freeze or get lost. Talk to your pharmacist for advice on travel storage.
The safety of this medicine during pregnancy is not fully established. If you are pregnant or planning to become pregnant, talk to your doctor to weigh the potential benefits against the risks to your baby.
Do not use the medication if it has been frozen, even if it thaws completely. Freezing can destroy the active protein in the medicine. Safe disposal is necessary; talk to your pharmacist if you need a replacement.
While this medicine reduces your risk of bleeding, you should still avoid high-contact or high-injury sports (like football or rugby) that could cause serious internal trauma. Talk to your doctor about safe physical activities for your condition.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. MedlinePlus. A622046 Patient Information Monograph. Bethesda, MD: U.S. National Library of Medicine (NLM); 2025. [Accessed on 02 Jun. 2026]Check here
  2. Drugs.com Clinical Review Team. Emicizumab Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  3. U.S. Food and Drug Administration (FDA). 761083S000Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026]Check here
  4. U.S. Food and Drug Administration (FDA). 761083Orig1S000Chemr [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026]Check here
  5. Electronic Medicines Compendium (EMC). Emc Summary of Product Characteristics (SmPC). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  6. Hemlibra Epar Product Information En. [Accessed on 02 Jun. 2026]Check here
  7. HEMLIBRA® (emicizumab. [Accessed on 02 Jun. 2026]Check here

Country of origin

India

Manufacturer/Marketer address

Roche Diagnostics India Pvt Ltd, 501 B, Silver Utopia, Cardinal Gracious Road, Chakala Road, Andheri East, Mumbai €“ 400069
Other Info - HEM0275
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