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  1. Home
  2. Medicine

  3. Haptoket Tablet

Prescription drug
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Haptoket Tablet, Pack of 1 Tablet
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Composition :

KETOCONAZOLE-200MG

Consume Type :

ORAL

Return Policy :

Not Returnable

About Haptoket Tablet

Haptoket Tablet is indicated to treat various systemic fungal infections such as blastomycosis (infection caused by Blastomyces fungus), chromomycosis (chronic infection of the skin and subcutaneous tissue), Coccidioidomycosis (infection caused by Coccidioides fungus), paracoccidioidomycosis (infection caused by Paracoccidioides fungus) and histoplasmosis (lung infection caused by Histoplasma fungus).

Haptoket Tablet contains ketoconazole, which works by destroying fungal cell membranes that are essential for their survival. Thus, kills fungi and treats the fungal infection.

Some people may experience headache, nausea, stomach pain, and diarrhoea as side effects. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to ketoconazole or any other medicines, please tell your doctor. If you are pregnant or planning for pregnancy, inform your doctor before taking Haptoket Tablet. Avoid breastfeeding while taking Haptoket Tablet as it may be excreted in breast milk. Haptoket Tablet is not recommended for children below 2 years of age.

Uses of Haptoket Tablet

Haptoket Tablet is used in the treatment of severe fungal infections when other antifungal treatments are unsuitable or ineffective. The detailed uses of Haptoket Tablet include:

  • Treatment of systemic fungal infections: Haptoket Tablet is prescribed for serious fungal infections affecting internal organs such as the lungs, liver, or skin.
  • Management of fungal infections resistant to first-line therapy: Haptoket Tablet is used when alternative antifungal agents are not tolerated or fail to provide adequate results.
  • Destruction of fungal cell membranes: Haptoket Tablet works by disrupting the integrity of fungal cell membranes, leading to cell death and resolution of the infection.

Have a query?

Directions for Use

  • Haptoket Tablet can be taken with or without food.
  • Your doctor will decide the dose and duration depending on your condition.
  • Swallow the medicine as a whole with a glass of water.
  • Do not crush, chew, or break Haptoket Tablet as it may affect the way the medication is absorbed.

Medicinal Benefits

  • Haptoket Tablet is an antifungal used to treat severe fungal infections.
  • It is used only when other effective antifungal therapies are not available or tolerated and if potential benefits outweigh potential risks.
  • It destroys fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thus, kills fungi and treats the fungal infection.

How Haptoket Tablet Works

Haptoket Tablet contains Ketoconazole which works by destroying fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thus, kills fungi and treats the fungal infection.

Storage

• Store in a cool and dry place away from sunlight.• Keep Haptoket Tablet out of the sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Haptoket Tablet
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

What if I have taken an overdose of Haptoket Tablet

Never take more than the prescribed dose. When Haptoket Tablet is used at high doses, it may, though unlikely, result in decreased testosterone levels, sperm production, and an issue with the adrenal glands (adrenal insufficiency). Seek emergency medical help if an overdose is suspected.

Drug Warnings

  • If you are allergic to Ketoconazole or any other medicines, please tell your doctor.
  • If you are pregnant or planning for pregnancy, inform your doctor before taking Haptoket Tablet.
  • Avoid breastfeeding while taking Haptoket Tablet as it may be excreted in breast milk.
  • You are recommended to avoid alcohol consumption with Haptoket Tablet.
  • If you have a loss of appetite, tiredness, stomach pain, vomiting, yellowing of skin or eyes, dark urine, or light-coloured stools, inform your doctor immediately as they might be symptoms of hepatotoxicity (liver damage). 

Drug-Drug Interactions

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KetoconazoleDronedarone
Critical
KetoconazoleSilodosin
Critical

Drug-Drug Interactions

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KetoconazoleDronedarone
Critical
How does the drug interact with Haptoket Tablet:
When Dronedarone is taken with Haptoket Tablet, it can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Haptoket Tablet with Dronedarone is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
KetoconazoleSilodosin
Critical
How does the drug interact with Haptoket Tablet:
Coadministration of Silodosin with Haptoket Tablet may lead to side effects including extremely low blood pressure, and increased heart rate.

How to manage the interaction:
Taking Haptoket Tablet with Silodosin together is not recommended as it can result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, headache, flushing, nasal congestion, heart palpitation. Do not discontinue any medications without consulting a doctor.
KetoconazoleDofetilide
Critical
How does the drug interact with Haptoket Tablet:
When Dofetilide is taken with Haptoket Tablet, it can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Haptoket Tablet with Dofetilide is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
KetoconazoleLomitapide
Critical
How does the drug interact with Haptoket Tablet:
When Lomitapide is taken with Haptoket Tablet, it may increase the risk of side effects.

How to manage the interaction:
Taking Haptoket Tablet with Lomitapide is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. However, if you experience symptoms such as fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, vomiting, dark urine, light stools, and skin or eye yellowing, decreased hunger, consult the doctor immediately. Do not stop using any medications without talking to the doctor.
KetoconazoleNisoldipine
Critical
How does the drug interact with Haptoket Tablet:
When Nisoldipine is taken with Haptoket Tablet, it can increase the blood levels of Nimodipine which may lead to serious side effects (irregular heart rhythm, fluid retention, swelling, and extremely low blood pressure).

How to manage the interaction:
Taking Haptoket Tablet with Nisoldipine can cause an interaction, but it can be taken if prescribed by the doctor. However, if you experience irregular heart rhythm, fluid retention, swelling, and extremely low blood pressure while using these medications, consult the doctor. Do not stop using any medications without talking to a doctor.
KetoconazoleConivaptan
Critical
How does the drug interact with Haptoket Tablet:
Using conivaptan together with Haptoket Tablet may significantly increase the blood levels of conivaptan, which may increase the risk of side effects.

How to manage the interaction:
Taking Haptoket Tablet with Conivaptan is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. However, if you experience difficulty swallowing, trouble speaking, muscle weakness, trouble controlling body movements, confusion, mood changes, seizures(fits), consult the doctor immediately. Do not discontinue any medication without consulting a doctor.
KetoconazoleIsavuconazole
Critical
How does the drug interact with Haptoket Tablet:
Co-administration of Haptoket Tablet and Isavuconazole can significantly increase the blood levels of Isavuconazole, which may increase the risk of side effects.

How to manage the interaction:
Taking Isavuconazole with Haptoket Tablet is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. However, if you experience symptoms like nausea, stomach pain, headache while on therapy with these drugs, consult the doctor. Do not discontinue any medication without consulting a doctor.
KetoconazoleEplerenone
Critical
How does the drug interact with Haptoket Tablet:
Coadministration of Haptoket Tablet with Eplerenone can increase the levels of blood potassium which can lead to kidney damage and irregular heart rate.

How to manage the interaction:
Taking Haptoket Tablet with Eplerenone is not recommended as it can result in an interaction, but it can be taken if a doctor has advised it. However, if you notice any symptoms of headaches, irritation, confusion, edema (swelling caused by too much fluid accumulation), weakness, palpitations, or constipation, you should contact a doctor immediately. Do not stop using any medications without the doctor's advice.
KetoconazolePimozide
Critical
How does the drug interact with Haptoket Tablet:
When Pimozide is taken with Haptoket Tablet, it can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Haptoket Tablet with Pimozide is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
KetoconazoleRegorafenib
Critical
How does the drug interact with Haptoket Tablet:
When Regorafenib is taken with Haptoket Tablet, it can increase the levels of Regorafenib, which may lead to side effects.

How to manage the interaction:
Taking Regorafenib with Haptoket Tablet is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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KETOCONAZOLE-200MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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KETOCONAZOLE-200MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Consumption of grapefruit or its juice with Haptoket Tablet may result in side effects such as joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, dark urine, light colored stools, and yellowing of the skin or eyes. Avoid consuming grapefruit, grapefruit juice, or any supplements that include grapefruit extract while taking Haptoket Tablet.

Diet & Lifestyle Advise

  • Avoid high-risk areas such as renovated buildings, construction sites, pigeon or chick coops, and caves.
  • Wear a respiratory mask when there is a risk of exposure to spores.
  • People with a weak immune system are advised to avoid activities that involve close contact with dust or dirt including digging, yard work, and gardening.
  • Close windows and stay inside during dust storms.
  • Clean skin injuries well with soap and water to reduce the risk of developing a skin infection.

Habit Forming

No

Therapeutic Class

ANTIFUNGALS - ORAL

Haptoket Tablet Substitute

Substitutes safety advice
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Haptoket Tablet as it may increase the risk of liver damage and cause adverse effects.

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Pregnancy

Consult your doctor

Haptoket Tablet is a Category C pregnancy drug and is given to pregnant women only if the doctor thinks the benefits outweigh the risks.

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Breast Feeding

Unsafe

Haptoket Tablet may be excreted in breast milk. Therefore, it is recommended to avoid breastfeeding while taking Haptoket Tablet.

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Driving

Caution

Haptoket Tablet may cause dizziness or drowsiness. Therefore, drive only if you alert after taking Haptoket Tablet.

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Liver

Unsafe

Haptoket Tablet is contraindicated in patients with chronic or acute liver disease. Therefore, inform your doctor if you have any Liver diseases/conditions.

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Kidney

Consult your doctor

If you have any concerns regarding the use of Haptoket Tablet in patients with kiver diseases/conditions, consult a doctor.

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Children

Consult your doctor

Haptoket Tablet is not recommended for children below 2 years of age. For children above 2 years, it is recommended to use only if the doctor has determined that benefits outweigh risks.

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Heart

If you have any concerns regarding the use of Haptoket Tablet in patients with heart diseases/conditions, consult a doctor.

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Geriatrics

Caution

Haptoket Tablet should be used with caution in elderly patients. Please consult your doctor before use.

FAQs

Haptoket Tablet belongs to a class of drugs called antifungals indicated to treat various systemic fungal infections such as blastomycosis (infection caused by Blastomyces fungus), chromomycosis (chronic infection of the skin and subcutaneous tissue), Coccidioidomycosis (infection caused by Coccidioides fungus), paracoccidioidomycosis (infection caused by Paracoccidioides fungus) and histoplasmosis (lung infection caused by Histoplasma fungus).

Haptoket Tablet works by destroying fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thus, kills fungi and treats the fungal infection.

Haptoket Tablet is not recommended to treat fungal meningitis (fungal infection spreads to the brain and spinal cord) as it poorly penetrates into the cerebrospinal fluid. Therefore, inform your doctor if you have fungal meningitis so that appropriate medication may be prescribed.

You are recommended to avoid foods containing chocolate and caffeine such as cocoa beans, tea, coffee, cola and energy drinks while taking Haptoket Tablet as it may increase the adverse effects of caffeine such as drowsiness, nervousness or nausea.

You are not recommended to take Haptoket Tablet with simvastatin (lipid-lowering drug) as co-administration of these medicines may cause muscle problems. Therefore, please consult a doctor before taking Haptoket Tablet with other medicines.

No, you are not recommended to stop taking Haptoket Tablet without consulting your doctor as it may cause recurring infection. Therefore, take Haptoket Tablet for as long as your doctor has prescribed it and if you experience any difficulty while taking Haptoket Tablet, please consult your doctor.

Country of origin

India
Other Info - HA31419

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Santoshini Reddy GDoctor badge

Reviewed By

Santoshini Reddy G

M Pharmacy

Last Updated

Oct 13, 2025 | 1:22 PM IST

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Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/018533s040lbl.pdf
  2. https://www.drugs.com/mtm/ketoconazole.html
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