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Hamostat 250mg Injection is used to treat excessive bleeding caused by the rapid breakdown of blood clots after surgery. It contains aminocaproic acid, which prevents the breakdown of blood clots. This medicine may cause side effects such as nausea, vomiting, stomach pain or cramping, diarrhoea, headache, dizziness, confusion, pain or redness at the site of injection, blurred or decreased vision, anxiety, ringing in the ears, and swelling of the arms, hands, feet, or lower legs. Inform your doctor if you are allergic to any medicines or have any pre-existing medical conditions before starting Hamostat 250mg Injection.

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Written By ,
Reviewed By Praneetha Akunuri , M.Pharmacy
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More about the Product

Manufacturer/Marketer :

Samarth Life Sciences Pvt Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Hamostat 250mg Injection

Hamostat 250mg Injection is a specialised medicine prescribed to treat and control excessive bleeding in the body. While oral tablets and syrups exist for outpatient management, this article focuses on the parenteral (intravenous injection or infusion) form. It is primarily used when blood clots break down too quickly, leading to severe blood loss during or after major surgical procedures or due to specific bleeding disorders. By helping the body hold onto its natural seals, this medicine plays a critical role in preventing dangerous complications from bleeding.

Because this medicine is delivered directly into a vein, it is typically given in a hospital or clinical setting by a healthcare provider. The frequency and duration of your treatment will depend entirely on your specific medical condition and how well your body responds. During your recovery, your doctor may suggest simple lifestyle modifications, such as avoiding strenuous movements, to help support your healing process.

While this medicine is highly effective, some people may experience mild side effects like an upset stomach, stuffy nose, or slight dizziness. These symptoms are usually temporary and go away as your body adjusts to the medicine. However, if you notice any severe reactions, such as intense muscle pain or difficulty breathing, you must inform your healthcare provider immediately.

Before you receive this medicine, it is vital to discuss your complete medical history with your doctor. Talk to your doctor if you have kidney disease, heart issues, or a history of blood clotting problems. Do not receive this if you have an active blood clotting disorder, such as disseminated intravascular coagulation (DIC), unless you are simultaneously being treated with heparin under strict medical supervision.

This medicine can interact with other substances, including certain prescription drugs that promote clotting, which may increase your risk of unwanted blood clots. It is also important to avoid smoking and limit alcohol during your treatment, as these can affect your blood vessels and overall circulation. If you are pregnant, planning to breastfeed, or are caring for an elderly patient, talk to your doctor to ensure this treatment is safe and appropriate.

Uses of Hamostat 250mg Injection

Hamostat 250mg Injection is used to control excessive bleeding in certain medical conditions and after some surgical procedures. The detailed uses of Hamostat 250mg Injection are as follows:

  • Severe bleeding after heart surgery: Hamostat 250mg Injection helps by stabilising formed blood clots, preventing excessive blood loss during or immediately after complex cardiac procedures.
  • Bleeding control after prostate surgery: Hamostat 250mg Injection helps reduce post-operative bleeding in the urinary tract by protecting delicate clotting seals from breaking down too quickly.
  • Managing systemic bleeding disorders and haemophilia: Hamostat 250mg Injection helps control acute bleeding episodes in individuals with haemophilia or conditions where the body naturally breaks down clots too quickly.
  • Reversing clot-dissolving medicines: It is used to control severe bleeding caused by overactivity or overdose of thrombolytic (clot-busting) therapies.

Key Benefits

Hamostat 250mg Injection provides important benefits by helping control excessive bleeding and supporting recovery after major medical procedures. The key benefits of Hamostat 250mg Injection are as follows:

  • Rapid Bleeding Control: The primary benefit of Hamostat 250mg Injection is its ability to rapidly and safely control heavy bleeding, providing vital peace of mind during major surgeries. By keeping blood loss to a minimum, it helps protect your vital organs and stabilises your blood pressure during critical medical procedures.
  • Supports Recovery: Additionally, this medicine helps speed up your overall recovery by reducing the need for repeated blood transfusions. By keeping your natural blood clots intact, it allows surgical wounds and damaged tissues to heal more efficiently, helping you get back on your feet sooner.
Side effects of Hamostat 250mg Injection 20ml
  • Reduce salt intake to minimize fluid buildup.
  • Use compression stockings, sleeves, or gloves.
  • Gently massage the affected area towards the heart.
  • Protect the swollen area from injury and keep it clean.
  • Use lotion or cream to keep the skin moisturized.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Managing Medication-Triggered malaise (Feeling Unwell): A Step-by-Step Guide:
  • If you experience persistent or severe malaise (a general feeling of discomfort, illness, or unease) after taking medication, seek medical attention immediately.
  • Inform your doctor about the medication you're taking and the symptoms you're experiencing.
  • Your treatment plan may be modified, which may include adjusting the dosage, substituting with an alternative medication, or discontinuing the medication. Additionally, certain lifestyle changes may be recommended to help manage symptoms.
  • To manage malaise symptoms, follow your doctor's advice, such as getting plenty of rest, staying hydrated, and practicing stress-reducing techniques.
  • Track your symptoms regularly and report any changes or concerns to your healthcare provider to ensure the malaise is managed effectively.
  • If you experience or encounter any severe allergic reaction, stop using medication and consult the doctor right away.
  • Tell your doctor about the allergic reaction, including the medication taken and any symptoms experienced.
  • Your doctor will evaluate the severity of the reaction and determine the best course of action.
  • To ensure a full recovery, follow your doctor's advice, attend scheduled follow-up appointments, and undergo recommended tests to monitor progress and adjust treatment as needed.
  • Injection site reaction can include numbness or redness.
  • Get a physical examination, follow your doctor's instructions, if it worsens or gets swollen.
  • Apply cold compress for pain relief.
  • Practice good hygiene and keep the injection site away from heat and pressure.
  • Exercising regularly helps lower the risk of heart problems.
  • Maintain a healthy diet, including vegetables and fruits.
  • Rest well; get enough sleep.
  • Manage stress with yoga and meditation.
  • Limit alcohol and smoking.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Hamostat 250mg Injection is administered by the doctor or healthcare professional.
  • Do not self-administer.

How Hamostat 250mg Injection Works

Hamostat 250mg Injection stops excessive bleeding by protecting fibrin clots, your body's natural seals, from breaking down too early during surgery or bleeding disorders. As a synthetic lysine analogue, aminocaproic acid competitively inhibits plasminogen activators and plasmin, preventing these clot-dissolving enzymes from breaking down seals prematurely so injured blood vessels can heal undisturbed.
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Alcohol

Consult your doctor

Hamostat 250mg Injection may interact with alcohol, increasing the risk of dizziness. Please consult the doctor before using Hamostat 250mg Injection if you consume alcohol.

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Pregnancy

Consult your doctor

Hamostat 250mg Injection should be used during pregnancy only if necessary. If you are pregnant or planning to become pregnant, please consult your doctor before using Hamostat 250mg Injection.

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Breast Feeding

Caution

It is unknown whether aminocaproic acid passes into breast milk. Therefore, consult your doctor if you are a breastfeeding mother. Your doctor will prescribe Hamostat 250mg Injection only if the benefits outweigh the risks.

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Driving

Consult your doctor

Do not drive or operate machinery during treatment with Hamostat 250mg Injection, as it may cause blurred vision or dizziness.

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Liver

Consult your doctor

Please consult your doctor if you have any pre-existing history of liver diseases before using Hamostat 250mg Injection.

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Kidney

Consult your doctor

Please consult your doctor if you have any pre-existing history of kidney diseases before receiving Hamostat 250mg Injection.

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Children

Consult your doctor

Hamostat 250mg Injection is not recommended for children below 12 years and should not be given to newborns. Please consult a doctor before administering Hamostat 250mg Injection to children.

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Heart

Caution

Please consult your doctor if you have any pre-existing history of heart disease before receiving Hamostat 250mg Injection.

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Geriatrics

Consult your doctor

Hamostat 250mg Injection should be used in the elderly only if advised by a doctor, as dose adjustment may be required.

What if I have taken an overdose of Hamostat 250mg Injection

In case of a suspected overdose, seek emergency medical care immediately. Symptoms of an overdose may include severe lightheadedness, fainting, sudden numbness, or signs of a new blood clot in your lungs or limbs.

Diet & Lifestyle Advise

  • Stay Hydrated: Stay well-hydrated by drinking plenty of water, as this helps your kidneys safely clear the medicine from your body.
  • Avoid Strenuous Activities: Avoid strenuous exercises, heavy lifting, or contact sports while recovering to minimise the risk of accidental bruising or internal bleeding.
  • Eat Iron-Rich Foods: Incorporate iron-rich foods, such as leafy green vegetables, beans, and lean meats, into your meals to help your body naturally recover from blood loss.
  • Avoid Certain Pain Relievers: Do not take over-the-counter pain relievers like aspirin, ibuprofen, or naproxen without consulting your doctor first, as these medicines affect platelet function and increase bleeding risks.
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How Soon It Starts Working

The time required for Hamostat 250mg Injection to start to work: The effect of Hamostat 250mg Injection can be observed from 1 to 72 hours after administration. The time for which the effects of Hamostat 250mg Injection last: Hamostat 250mg Injection effect usually lasts for approximately 3-4 hours.

What if you forget to take Hamostat 250mg Injection

Because this medicine is typically given by medical professionals in a hospital, it is highly unlikely that you will miss a dose. If you are receiving this treatment at home and miss a scheduled infusion, inject it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed one and return to your regular schedule. Do not take a double dose to make up for a missed one. If you are unsure what to do, talk to your doctor or pharmacist.

Storage

• Store Hamostat 250mg Injection injection at controlled room temperature, typically between 20°C and 25°C (68°F to 77°F).
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Keep Refrigerated. Do not freeze.

Drug Warnings

  • Inspect the Vial: Always visually inspect the liquid vial before use; do not inject the medicine if it looks cloudy, is discoloured, or contains visible floating particles.
  • Give the Injection Slowly: Ensure the injection is given slowly, as a rapid infusion can cause a sudden, dangerous drop in your blood pressure or trigger an irregular heartbeat.
  • Report Muscle Symptoms: Tell your doctor immediately if you develop sudden, unexplained muscle pain or weakness, as this medicine can occasionally cause muscle tissue damage.
  • Watch for Blood Clots: Remain vigilant for any signs of blood clots, such as sudden chest tightness, coughing, or localised leg swelling, and seek immediate emergency care if they occur.
  • Attend Follow-Up Appointments: Keep all follow-up medical appointments and complete any scheduled blood or urine tests so your doctor can monitor your kidneys and clotting levels safely.

Drug-Drug Interactions

verifiedApollotooltip
  • Blood-Clotting Factor Concentrates: Avoid taking this medicine alongside blood-clotting factor concentrates or anti-inhibitor coagulant complexes, as combining these treatments can severely increase your risk of developing dangerous blood clots.
  • Estrogen-Containing Products: Combining this medicine with oral contraceptives or hormone replacement therapy (HRT) can additively increase the risk of blood clots. 
     
Aminocaproic acidCarfilzomib
Severe

Drug-Drug Interactions

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Aminocaproic acidCarfilzomib
Severe
How does the drug interact with Hamostat 250mg Injection 20ml:
Coadministration of Hamostat 250mg Injection 20ml and Carfilzomib can increase the risk of developing blood clots.

How to manage the interaction:
Co-administration of Carfilzomib with Hamostat 250mg Injection 20ml can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any symptoms, such as chest pain, shortness of breath, redness or swelling in an arm or leg, or weakness, contact a doctor right away. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • No clinically significant food interactions are known with Hamostat 250mg Injection when used as directed.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTIFIBRINOLYTIC AGENTS]

FAQs

Hamostat 250mg Injection is used to treat excessive bleeding caused by the rapid breakdown of blood clots, which can occur during surgery, in bleeding disorders, or in certain cancers.
Hamostat 250mg Injection contains aminocaproic acid as its active ingredient, which works by preventing the breakdown of blood clots. It inhibits plasmin, a substance that dissolves clots, helping in the control of excessive bleeding.
No, Hamostat 250mg Injection is not habit-forming. Please contact a doctor if you have any concerns.
Hamostat 250mg Injection causes side effects such as nausea, vomiting, stomach pain or cramping, diarrhoea, headache, dizziness, confusion, pain or redness at the site of injection, blurred or decreased vision, anxiety, ringing in the ears, and swelling of the arms, hands, feet, or lower legs. Contact a doctor if these side effects persist or worsen.
You are recommended not to stop taking Hamostat 250mg Injection even if you feel better, as you may experience unwanted side effects. Therefore, continue to take Hamostat 250mg Injection for the prescribed duration as advised by your doctor.
Hamostat 250mg Injection should be stored at temperatures not exceeding 25°C. Do not freeze. Keep it protected from light and out of reach of children.
This medicine is given as an injection or a slow infusion directly into a vein. Because it is a parenteral treatment, it is typically given by a trained healthcare professional in a clinic or hospital setting. Talk to your doctor for more details about your administration schedule.
Yes, because this medicine stops the natural breakdown of blood clots, it can occasionally cause unwanted clots to form inside your blood vessels. Your medical team will monitor you closely to reduce this risk. Talk to your doctor if you have a history of blood clots.
Contact your doctor immediately if you experience unusual or severe muscle pain, tenderness, or weakness. In rare instances, this medicine can cause muscle damage that requires prompt medical evaluation. Talk to your doctor right away if you notice these symptoms.
Yes, but your doctor will need to monitor you very closely. Because your kidneys clear this medicine from your body, kidney disease can cause the drug to build up, which may require your doctor to adjust your dose. Talk to your doctor about your kidney health before treatment.
This medicine should only be used during pregnancy if your doctor determines that the clinical benefit is absolutely necessary and outweighs any risks. If you are pregnant, planning to become pregnant, or breastfeeding, talk to your doctor before starting this treatment.
Injecting this medicine too rapidly into your vein can cause sudden, serious side effects, such as a sharp drop in blood pressure, a slow heart rate, or an irregular heart rhythm. For your safety, healthcare providers will always give this infusion slowly. Talk to your doctor if you have concerns.
You should avoid taking common pain relievers like aspirin, ibuprofen, or naproxen while using this medicine unless your doctor explicitly says it is safe. These pain relievers affect platelet function and can make it harder to control your bleeding. Talk to your doctor or pharmacist for safe alternatives.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Samarth House, 168, Bangur Nagar, Off Link Road, Near Ayappa Temple & Kallol Kali Temple, Goregaon (W), Mumbai - 400 090.
Other Info - HAM0003
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