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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Gufipol Injection 1's is used to treat bacterial infections such as urinary tract infections, meningitis, bloodstream infections, and corneal and subconjunctival eye infections caused by susceptible organisms. It contains Polymyxin B, which destroys bacterial cell membranes and kills infection-causing bacteria. Thereby, it helps treat bacterial infections. In some cases, Gufipol Injection 1's may cause side effects such as pain at the injection site, flushing, dizziness, and diarrhoea.

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Whats That

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Synonym :

POLYMYXIN B SULPHATE

Manufacturer/Marketer :

Gufic Bioscience Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

About Gufipol Injection 1's

Gufipol Injection 1's belongs to the group of medicines called antibiotics used to treat bacterial infections such as urinary tract infections, meningitis, bloodstream infections, and corneal and subconjunctival eye infections caused by susceptible organisms.

Gufipol Injection 1's contains Polymyxin B, which works by destroying bacterial cell membranes and killing infection-causing bacteria. Thereby, it helps treat bacterial infections.

In some cases, Gufipol Injection 1's may cause side effects such as pain at the injection site, flushing, dizziness, and diarrhoea. Most of these side effects may not require medical attention and resolve gradually over time. However, consult a doctor if the side effects persist or worsen.

Let the doctor know if you are allergic to any of the components in Gufipol Injection 1's. Consult the doctor if you are pregnant or breastfeeding. Keep your doctor informed about your health condition and medications to rule out any side effects/interactions.

Uses of Gufipol Injection 1's

Gufipol Injection 1's is used in the treatment of Bacterial infections. The detailed uses of Gufipol Injection 1's are as follows:<br/>• Treat bloodstream infections: Gufipol Injection 1's is effective against septicemia caused by resistant gram-negative bacteria such as Pseudomonas aeruginosa, Klebsiella pneumoniae, and Escherichia coli.<br/>• Manage meningitis: Gufipol Injection 1's is administered intrathecally to treat bacterial meningitis, especially when caused by Pseudomonas aeruginosa or Haemophilus influenzae.<br/>• Treat urinary tract infections: Gufipol Injection 1's helps eliminate gram-negative pathogens in complicated or hospital-acquired UTIs.<br/>• Address pulmonary infections: Gufipol Injection 1's is used in cases of pneumonia and pulmonary embolism caused by multidrug-resistant gram-negative bacteria.<br/>

Directions for Use

• Gufipol Injection 1's will be administered by a healthcare professional.• Do not self-administer it.

Medicinal Benefits

Gufipol Injection 1's belongs to the group of medicines called antibiotics used to treat bacterial infections such as urinary tract infections, meningitis, bloodstream infections, and corneal and subconjunctival eye infections caused by susceptible organisms. Gufipol Injection 1's contains Polymyxin B, which works by destroying bacterial cell membranes and killing infection-causing bacteria. Thereby, it helps treat bacterial infections.

How Gufipol Injection 1's Works

Gufipol Injection 1's contains Polymyxin B, which works by destroying bacterial cell membranes and killing infection-causing bacteria. Thereby, it helps treat bacterial infections.

Storage

• Store in a cool and dry place away from sunlight.
• Keep Gufipol Injection 1's out of reach and sight of children.
• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Gufipol Injection 1's

As Gufipol Injection 1's is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. However, if you think there has been an overdose or experiencing any adverse events, get medical care right away.

Drug Warnings

Do not receive Gufipol Injection 1's if you are allergic to any of its components. Consult the doctor if you are pregnant or breastfeeding. Seek medical attention if you experience symptoms of kidney problems (unable to pass urine, change in how much urine you pass), nerve problems (weakness, irritation, feeling sleepy, blurred eyesight, change in balance, numbness or tingling around the mouth or in the arms or legs, or trouble breathing), or Clostridium difficile associated diarrhoea/CDAD (stomach pain, cramps, very loose, watery, or bloody stool). Let the doctor know if you are taking any prescription/non-prescription medicines, including supplements or herbal products.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Gufipol Inj:
Taking Everolimus and Gufipol Inj together may increase the risk of kidney problems.

How to manage the interaction:
There may be a possibility of interaction between Everolimus and Gufipol Inj, but it can be taken if prescribed by a doctor. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, swelling, difficulty breathing, bone pain, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Gufipol Inj:
Taking Adefovir dipivoxil with Gufipol Inj may increase the risk of side effects.

How to manage the interaction:
Although taking Gufipol Inj and Adefovir dipivoxil together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience nausea, vomiting, decreased hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, bone pain, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Gufipol Inj:
Taking Gufipol Inj with Pancuronium together can cause breathing problems.

How to manage the interaction:
Taking Gufipol Inj with Pancuronium together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any breathing problems, consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Gufipol Inj:
Co-administration of Gufipol Inj and Vecuronium together may cause serious breathing problems.

How to manage the interaction:
Taking Gufipol Inj with Vecuronium together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any breathing difficulty, consult the doctor. Do not stop using any medications without a doctor's advice.
Polymyxin bTubocurarine
Severe
How does the drug interact with Gufipol Inj:
Co-administration of Gufipol Inj and Tubocurarine together may cause serious breathing problems.

How to manage the interaction:
There may be a possibility of interaction between Gufipol Inj and Tubocurarine, but it can be taken if prescribed by a doctor. However, if you experience any breathing difficulty, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Gufipol Inj:
Coadministration of Amikacin with Gufipol Inj may increase the risk of severe side effects.

How to manage the interaction:
Although taking Amikacin and Polymyxin- b together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor if you experience ringing in the ears, difficulty breathing, vomiting, irregular urination, swelling, muscle pain, dizziness, or palpitation. Do not stop using any medications without talking to a doctor.
Polymyxin bCholera, live attenuated
Severe
How does the drug interact with Gufipol Inj:
Taking Gufipol Inj and Cholera together may lead to a decrease in the effectiveness of the vaccine.

How to manage the interaction:
There may be a possibility of interaction between Gufipol Inj and Cholera, live attenuated, but it can be taken if prescribed by a doctor. It is advised not to receive the cholera vaccination until at least 14 days after finishing your Gufipol Inj therapy in order to ensure an appropriate immune response. Do not discontinue any medications without a doctor's advice.
Polymyxin bBacitracin
Severe
How does the drug interact with Gufipol Inj:
Taking Gufipol Inj and Bacitracin together can increase the risk of kidney and inner ear damage

How to manage the interaction:
Although taking Gufipol Inj and Bacitracin together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience ringing in the ears, hearing loss, vertigo, nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, swelling, difficulty breathing, bone pain, muscle pain, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Gufipol Inj:
Co-administration of Gufipol Inj may increase the effects of Suxamethonium when taken in combination.

How to manage the interaction:
Co-administration of Suxamethonium with Gufipol Inj can result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without a doctor's advice.
How does the drug interact with Gufipol Inj:
Taking Tobramycin with Gufipol Inj can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between Tobramycin and Gufipol Inj, you can take these medicines together if prescribed by a doctor. However, if you experience hearing loss, ringing in the ears, difficulty breathing, nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include whole grains, fruits, and vegetables in your diet. 
  • Taking probiotics after antibiotic treatment and eating high-fibre and prebiotic foods may help reduce side effects and support digestion.
  • Exercising regularly helps in improving overall health. 
  • Rest well, and get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress.
  • Avoid processed and fried food.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS
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Alcohol

Consult your doctor

It is not known if alcohol interacts with Gufipol Injection 1's. Please consult the doctor.

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Pregnancy

Caution

The safety of polymyxin B in pregnancy has not been established. If you are pregnant or planning pregnancy, inform the doctor before receiving Gufipol Injection 1's.

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Breast Feeding

Caution

If you are breastfeeding, inform your doctor before receiving Gufipol Injection 1's. Caution is advised while administering Gufipol Injection 1's to lactating women.

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Driving

Consult your doctor

It is unknown if Gufipol Injection 1's affects your ability to drive. Drive only if you are alert.

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Liver

Consult your doctor

If you have a history of liver problems, inform the doctor before receiving Gufipol Injection 1's.

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Kidney

Caution

If you have a history of kidney problems, inform the doctor before receiving Gufipol Injection 1's.

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Children

Safe if prescribed

Gufipol Injection 1's may be safe for use in children if prescribed by the doctor.

Have a query?

FAQs

Gufipol Injection 1's is used to treat Bacterial infections.

Gufipol Injection 1's works by destroying bacterial cell membranes and killing infection-causing bacteria. Thereby, it helps treat bacterial infections.

Diarrhoea might be a side effect of Gufipol Injection 1's. Drink enough fluids and eat non-spicy food if you experience diarrhoea. Consult the doctor if the condition persists or worsens.

Gufipol Injection 1's may cause nerve problems. Consult the doctor if you experience weakness, irritation, change in balance, feeling sleepy, blurred eyesight, trouble breathing, numbness or tingling sensation in the arms and legs.

Gufipol Injection 1's will be administered by a healthcare professional. Do not self-administer.

Yes, Gufipol Injection 1's is safe when used only under the doctor’s supervision. However, it may cause pain at the injection site, flushing, dizziness, and diarrhoea while using it.

The common side effects of Gufipol Injection 1's may include pain at the injection site, flushing, dizziness, and diarrhoea. Most of these side effects may not require medical attention and resolve gradually over time. However, consult a doctor if the side effects persist or worsen.

Country of origin

India

Manufacturer/Marketer address

37,1St Floor, Kamala Bhavan Ii, Swami Nityanand Road, Andheri (East), Mumbai - 400 069. (India).
Other Info - GUF0034

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