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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Gufilinoz Injection 300 ml is an antibiotic used in treating bacterial infections. This medicine stops the growth of infection-causing bacteria and thereby helps reduce various bacterial infections of the lungs (pneumonia) and skin. Some of the common side effects include headache, metallic taste, diarrhoea, nausea, vomiting, dizziness, constipation, indigestion and localized pain.
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Whats That

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Composition :

LINEZOLID-200MG

Manufacturer/Marketer :

Gufic Bioscience Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Gufilinoz Injection 300 ml

Gufilinoz Injection 300 ml belongs to the class of medicines called oxazolidinones used to treat bacterial infections of the lungs (pneumonia), and skin. It is also used to treat infections which are resistant to other antibiotics. Bacterial infections are caused due to the multiplication of harmful bacteria inside or on the body. Gufilinoz Injection 300 ml does not work against infections caused by the virus, including cold and flu.

Gufilinoz Injection 300 ml contains Linezolid. It treats infection by stopping the growth of infection-causing bacteria. 

Gufilinoz Injection 300 ml shows some common side-effects like thrush (fungal infection), headache, metallic taste, diarrhoea, nausea, vomiting, dizziness, constipation, indigestion and localized pain. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to consult your doctor if you experience these side effects persistently.

Inform your doctor before receiving this injection if you are pregnant or planning pregnancy. Gufilinoz Injection 300 ml passes into breastmilk and can cause diarrhoea and vomiting in infants; therefore, discontinue breastfeeding prior to and throughout the treatment. Avoid alcohol consumption while taking Gufilinoz Injection 300 ml as it may cause increased dizziness. Gufilinoz Injection 300 ml may cause dizziness and vision problems, so drive and operate machinery only if you are alert. Keep your doctor informed about your health condition and your ongoing medications to rule out any interactions.

Uses of Gufilinoz Injection 300 ml

Treatment of Bacterial infections

Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use.• Gufilinoz Injection 300 ml will be administered by the doctor or healthcare professional.• Do not self-administer.

Medicinal Benefits

Gufilinoz Injection 300 ml belongs to the class of medicines called oxazolidinones used to treat bacterial infections of the lungs (pneumonia), and skin. It is also used to treat infections which are resistant to other antibiotics. Gufilinoz Injection 300 ml contains Linezolid. It treats infection by stopping the growth of infection-causing bacteria. 

How Gufilinoz Injection 300 ml Works

Gufilinoz Injection 300 ml contains Linezolid. It treats infection by stopping the growth of infection-causing bacteria.

Storage

• Store in a cool and dry place away from sunlight.• Keep Gufilinoz Injection 300 ml out of reach and sight of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Gufilinoz Injection 300 ml

Gufilinoz Injection 300 ml is administered by a health care professional in a hospital setting. Hence, the chances of overdose are less. Overdose of Gufilinoz Injection 300 ml may cause wheezing, chest tightness, seizures, swelling of the face, lips, tongue, or throat, and severe diarrhea. Your doctor will initiate necessary measures when an overdose is suspected.

Drug Warnings

Let your doctor know before receiving Gufilinoz Injection 300 ml if you are allergic to any of its contents; Gufilinoz Injection 300 ml should not be taken if you are taking or have taken monoamine oxidase (MAO) inhibitors in the last 14 days. Inform your doctor if you have high blood pressure, overactive thyroid, phaeochromocytoma (tumour of adrenal glands), carcinoid syndrome (tumours of the hormone system), manic depression, schizophrenia, confusion or other mental problems. Inform your doctor if you have bruises or bleeding disorders, have anaemia (low red blood cells), are prone to infections, have a history of seizures, if you are on dialysis, have diarrhoea, kidney or liver problems. Consult your doctor immediately if you experience a throbbing headache, vision problems, loss of sensitivity or tingling/prickling sensation in arms and legs, persistent diarrhoea, nausea, vomiting, abdominal pain or rapid breathing. 

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Gufilinoz Injection 300 ml:
Coadministration of Entacapone with Gufilinoz Injection 300 ml might raise serotonin hormone levels in the body, affecting the brain and nerve cells.

How to manage the interaction:
Taking Entacapone with Gufilinoz Injection 300 ml is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Gufilinoz Injection 300 ml:
Using Carbamazepine with Gufilinoz Injection 300 ml can cause serotonin syndrome(a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Taking Carbamazepine and Gufilinoz Injection 300 ml together is not recommended, but it can be taken if prescribed by a doctor. However, if you experience symptoms such as confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, stomach pain, nausea, vomiting, and diarrhea, consult the doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Gufilinoz Injection 300 ml:
When Gufilinoz Injection 300 ml is taken with Sertraline, may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
taking Gufilinoz Injection 300 ml and Sertraline is not recommended, but it can be taken if prescribed by a doctor. If you notice any of these signs - like confusion, hallucination, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramps, nausea, vomiting, and diarrhoea-contact a doctor right away. Do not stop using any medications without a doctor's advice.
How does the drug interact with Gufilinoz Injection 300 ml:
Taking Gufilinoz Injection 300 ml with Methylphenidate together may increase the risk or severity of high blood pressure.

How to manage the interaction:
Taking Gufilinoz Injection 300 ml with Methylphenidate is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden and severe headaches, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and/or fainting, contact a doctor immediately. You may use methylphenidate only after you have been off Gufilinoz Injection 300 ml for at least 14 days. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Gufilinoz Injection 300 ml:
When Oxcarbazepine is taken with Gufilinoz Injection 300 ml, it can increase the risk of serotonin syndrome(a condition when your body has too much of a chemical called serotonin), further leading to side effects.

How to manage the interaction:
Taking Oxcarbazepine with Gufilinoz Injection 300 ml is not recommended, as it results in an interaction, it can be taken if advised by a doctor. However, if you experience symptoms such as confusion, hallucination (seeing or hearing things that do not exist), seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhoea, consult a doctor. Do not stop using any medications without a doctor’s advice.
How does the drug interact with Gufilinoz Injection 300 ml:
Taking Gufilinoz Injection 300 ml with Amitriptyline can increase the risk of serotonin syndrome (increased serotonin hormone).

How to manage the interaction:
Although using Gufilinoz Injection 300 ml and Amitriptyline together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have symptoms such as confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Inform a doctor if you have recently taken amitriptyline. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Gufilinoz Injection 300 ml:
Taking Rasagiline with Gufilinoz Injection 300 ml can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Gufilinoz Injection 300 ml with Rasagiline is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm, stomach cramp, nausea, vomiting, and diarrhea contact a doctor right away. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Gufilinoz Injection 300 ml:
Coadministration of Gufilinoz Injection 300 ml and Tetrabenazine can increase the risk of high blood pressure.

How to manage the interaction:
Taking Gufilinoz Injection 300 ml and Tetrabenazine together is not recommended as it can lead to an interaction, but it can be taken if a doctor advises. However, if you experience any symptoms like severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and fainting, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Gufilinoz Injection 300 ml:
Using Gufilinoz Injection 300 ml together with atomoxetine can cause high blood pressure.

How to manage the interaction:
Taking Gufilinoz Injection 300 ml with Atomoxetine is not recommended, consult a doctor before taking it. You should seek immediate medical attention if you experience sudden and severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and/or fainting. Do not stop using any medications without talking to a doctor.
How does the drug interact with Gufilinoz Injection 300 ml:
Taking Gufilinoz Injection 300 ml with Fentanyl may increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Although there is an interaction between Gufilinoz Injection 300 ml and Fentanyl, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, fever, excessive sweating, muscle pain, stomach cramps, vomiting, and diarrhoea. Do not discontinue any medications without consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Antibiotics can kill the useful bacteria in the stomach, which help in digestion. Therefore, you are advised to take foods rich in probiotics such as yoghurt/curd, kefir, sauerkraut, tempeh, kimchi, miso, kombucha, buttermilk, natto and cheese.
  • Eat fibre-rich food like whole grains, beans, lentils, berries, broccoli, peas and bananas.
  • Avoid foods rich in calcium, grapefruit and grapefruit juice as they might hinder the absorption of antibiotics.
  • Avoid consumption of alcohol and usage of tobacco.

 

Habit Forming

No

Therapeutic Class

ANTIBIOTICS
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Alcohol

Unsafe

Avoid consuming alcohol while taking Gufilinoz Injection 300 ml as it may cause increased dizziness.

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Pregnancy

Caution

There is no sufficient and rigorous research on pregnant women. However, if you are pregnant, inform your doctor. Your doctor may prescribe this medicine only if the possible benefit outweighs the potential risk to the foetus.

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Breast Feeding

Caution

If you are a breastfeeding mother, inform your doctor before receiving this medicine. Gufilinoz Injection 300 ml passes into breastmilk and can cause diarrhoea and vomiting in infants; therefore, discontinue breastfeeding prior to and throughout the treatment.

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Driving

Caution

Gufilinoz Injection 300 ml may cause dizziness and vision problems. So, drive only if you are alert.

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Liver

Caution

Long-term treatment with Gufilinoz Injection 300 ml may worsen your liver condition if you have liver problems. Dose adjustment may be needed. Please inform your doctor before taking Gufilinoz Injection 300 ml if you have liver impairment/liver disease or a history of liver conditions.

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Kidney

Caution

Gufilinoz Injection 300 ml does not require dose adjustment for kidney dysfunction as the majority of both drugs undergo nonrenal clearance. However, if you have kidney problems, inform your doctor before receiving this injection.

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Children

Safe if prescribed

Your doctor will weigh the benefits and potential risks before prescribing Gufilinoz Injection 300 ml for your children based on age and the condition of the child.

Have a query?

FAQs

Gufilinoz Injection 300 ml belongs to the class of medicines called oxazolidinones used to treat bacterial infections of the lungs (pneumonia), and skin. It is also used to treat infections which are resistant to other antibiotics.

Gufilinoz Injection 300 ml works by stopping the growth of infection-causing bacteria. Thus, it treats the infection.

Diarrhoea might be a side-effect of Gufilinoz Injection 300 ml. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you have prolonged diarrhoea with abdominal pain while on treatment with Gufilinoz Injection 300 ml, inform your doctor. Do not take anti-diarrheal medicine on your own.

Gufilinoz Injection 300 ml may cause oral or vaginal thrush or candidiasis, which is a fungal infection occurring due to the overgrowth of yeast-like fungus in the mouth/throat or vagina. Consult your doctor if the condition persists or worsens.

Gufilinoz Injection 300 ml may affect certain laboratory test results such as blood tests, blood sugar tests, and liver and kidney function tests. Inform the lab technician that you are on treatment with Gufilinoz Injection 300 ml.

Gufilinoz Injection 300 ml may cause anaemia due to a decrease in the number of red blood cells. This could also cause unexplained bleeding or bruising. Consult your doctor if you experience unexplained bleeding or bruising.

Country of origin

India

Manufacturer/Marketer address

37,1St Floor, Kamala Bhavan Ii, Swami Nityanand Road, Andheri (East), Mumbai - 400 069. (India).
Other Info - GUF0043

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