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  3. GRAVION GRANULES 5GM

GRAVION GRANULES 5GM, Pack of 1 SACHET
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Written By Lakshmithulasi Yarragunta ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
GRAVION GRANULES 5GM is used to prevent premature labour. It contains Allylestrenol which works by modulating the immune response of the pregnant women to prevent rejection of the embryo, allowing its attachment to the uterus and improving blood flow to the placenta. This medicine may sometimes cause side effects such as changes in weight, unwanted hair growth, menstrual disturbances, swelling, fever, headache, and fatigue. Inform the doctor if you are breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Composition :

ALLYLESTRENOL-5GM

Manufacturer/Marketer :

Obsearge

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About GRAVION GRANULES 5GM

GRAVION GRANULES 5GM is used to prevent premature labour. Premature labour can start before 37 completed weeks of pregnancy and can be caused by premature rupture of membranes, high blood pressure during pregnancy (pre-eclampsia) and poor diet. A miscarriage is an unexpected loss of pregnancy before 20 weeks of pregnancy. It mostly happens during the first trimester, or the first three months, of the pregnancy. 

GRAVION GRANULES 5GM contains “Allylestrenol”, a progestin (female hormones) that works by modulating the immune response of the pregnant women to prevent rejection of the embryo and allows its attachment to the uterus and improve blood flow to the placenta. GRAVION GRANULES 5GM prevents repeated miscarriage (pregnancy loss) and helps lower the risk of premature birth in pregnant women who have had a past premature delivery.

Take GRAVION GRANULES 5GM as prescribed by your doctor. You are advised to take GRAVION GRANULES 5GM for as long as your doctor has prescribed it for you. In some cases, you may experience certain common side effects, such as a change in weight, unwanted hair growth, menstrual disturbances, swelling over the body, fever, headache, and fatigue. Not everybody experiences these side effects. Most of the side effects of GRAVION GRANULES 5GM do not require medical attention and gradually resolve over time. Talk to your doctor if you feel any discomfort while taking GRAVION GRANULES 5GM.

Do not stop taking GRAVION GRANULES 5GM abruptly without your doctor’s advice, as it may cause heavy bleeding. Before starting GRAVION GRANULES 5GM, please inform your doctor if you have an allergy to GRAVION GRANULES 5GM and any medicines. Tell your doctor before using GRAVION GRANULES 5GM if you have had pre-eclampsia (high blood pressure during pregnancy), thromboembolic disorders (blood clot form in the blood), diabetes, depression, or epilepsy. GRAVION GRANULES 5GM may cause dizziness, so be cautious while driving and operating machinery. GRAVION GRANULES 5GM is not recommended for use in children. Inform your doctor if you are breastfeeding before taking GRAVION GRANULES 5GM. Inform your doctor about all medicines you are taking and about your health condition to rule out any unpleasant side effects.

Uses of GRAVION GRANULES 5GM

Treatment of Recurrent Miscarriage and premature labour.

Directions for Use

• GRAVION GRANULES 5GM can be taken with or without food as advised by your doctor.• Follow your doctor's instructions on the dosage and timing of this medication.• Swallow GRAVION GRANULES 5GM as a whole with a glass of water.• Do not crush, break, or chew it.

Medicinal Benefits

GRAVION GRANULES 5GM contains “Allylestrenol” which is a progestin (female hormones) which is used in pregnant women who have a recurrent and threatened miscarriage (abortion) and pregnant women who have delivered a baby too early (preterm) in the past. It works by modulating the immune response of the pregnant women to prevent rejection of the embryo and allow its attachment to the uterus, and improve blood flow to the placenta.  It also relaxes uterus muscles, thereby preventing premature labour. GRAVION GRANULES 5GM prevents repeated miscarriage and helps lower the risk of premature birth in pregnant women who have had a past premature delivery. Also, GRAVION GRANULES 5GM is used to treat intrauterine growth retardation (unborn baby is not growing at a normal rate), amenorrhoea (absence of menstrual periods due to lack of progesterone), irregular menses cycle, and premenstrual syndrome (symptoms include mood swings, tender breasts, food cravings, fatigue, irritability and depression that women can experience in the weeks before their menses period). On the other hand, GRAVION GRANULES 5GM is effective in the treatment of hot flashes in postmenopausal women and benign prostatic hyperplasia (noncancerous increase in the size of the prostate gland) in men.

How GRAVION GRANULES 5GM Works

GRAVION GRANULES 5GM contains â€œAllylestrenol”, a progestin (female hormones) that works by modulating the immune response of the pregnant women to prevent rejection of the embryo and allows its attachment to the uterus and improve blood flow to the placenta. GRAVION GRANULES 5GM prevents repeated miscarriage (pregnancy loss) and helps lower the risk of premature birth in pregnant women who have had a past premature delivery.

Storage

Keep GRAVION GRANULES 5GM out of the sight and reach of children.

What if I have taken an overdose of GRAVION GRANULES 5GM

Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

You should not take GRAVION GRANULES 5GM on your own without a doctor's advice. Before starting GRAVION GRANULES 5GM, please inform your doctor if you have an allergy to any medicines. Do not take GRAVION GRANULES 5GM if you have unusual vaginal bleeding that is not related to your pregnancy, liver disease, severe hypertension (high blood pressure), history of cancer of the breast, uterus or vagina. Tell your doctor before using GRAVION GRANULES 5GM if you have had preeclampsia (high blood pressure during pregnancy), thromboembolic disorders (blood clot form in the blood), diabetes, depression, epilepsy. Do not stop taking GRAVION GRANULES 5GM abruptly without your doctor’s advice as it may cause heavy bleeding. Let your doctor know if you are a breastfeeding mother. Your doctor will weigh the benefits and any potential risks before prescribing them to you. GRAVION GRANULES 5GM is not recommended for children younger than 16 years old. GRAVION GRANULES 5GM can cause dizziness and drowsiness. Use caution while driving a motor vehicle as dizziness or drowsiness may occur.

Diet & Lifestyle Advise

  • Eat a healthy and balanced diet rich in vegetables, fruits, whole grains for reduced risk of preterm delivery.

  • Try to include heart-healthy omega 3 fatty acid containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil and coconut oil.

  • Prefer more whole foods and grains instead of processed ones. Avoid the intake of processed foods, foods high in sugar and fat.

  • Avoid stress as it can increase the chances of preterm delivery. Try to enjoy and spent time with your loved ones to cope with stress and practice mindfulness techniques.

  • Do regular physical activity and yoga, it keeps you fit and helps improve blood circulation and regulates oxygen supply, thereby improve the chances of carrying your baby full term.

  • Quitting smoking is the best strategy to lower the risk of premature delivery.

  • Keep your weight under control.

  • Try to avoid alcohol as it can affect your stomach and intestine and limit the absorption of the important nutrients required by your body.

Habit Forming

No

Therapeutic Class

HORMONES
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Alcohol

Caution

There is not enough scientific data available for GRAVION GRANULES 5GM interaction with alcohol, hence it is best to consult a doctor.

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Pregnancy

Safe if prescribed

Safe if prescribed.

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Breast Feeding

Caution

Please consult your doctor before using GRAVION GRANULES 5GM during breastfeeding. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

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Driving

Caution

It is advised to drive with caution after taking GRAVION GRANULES 5GM as it may interfere with driving capabilities. It can make you feel drowsy.

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Liver

Caution

GRAVION GRANULES 5GM should be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

GRAVION GRANULES 5GM should be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Unsafe

GRAVION GRANULES 5GM is not indicated for use in children. Safety and effectiveness in pediatric patients less than 16 years of age have not been established.

Have a query?

FAQs

GRAVION GRANULES 5GM belongs to the category of a synthetic progesterone female hormone called progestin used to prevent premature labour.

GRAVION GRANULES 5GM contains Allylestrenol is a progestin (female hormone) that helps in maintaining pregnancy by promoting the attachment of the embryo to lining of the womb and improving blood flow to the placenta. It also relaxes the uterus muscles thereby preventing premature labor and repeated miscarriage.

Yes, GRAVION GRANULES 5GM is used to prevent the habitual miscarriage and regular abortion. Your doctor will decide whether you should continue or stop taking GRAVION GRANULES 5GM. Do not take medication of your own or self medicate.

No, GRAVION GRANULES 5GM is not a contraceptive. It should not be used as an effective form of birth control to prevent pregnancy.

Yes, GRAVION GRANULES 5GM may cause weight gain. It can be due to water retention. If you feel that you are gaining a lot of weight while taking GRAVION GRANULES 5GM, please consult your doctor.

GRAVION GRANULES 5GM should be taken in the dose and duration as prescribed by the doctor.

You should stop using GRAVION GRANULES 5GM and tell a doctor before using GRAVION GRANULES 5GM if you have uncontrolled high blood pressure (hypertension), unusual vaginal bleeding, liver disease, liver cancer, jaundice during pregnancy, circulation problems or bleeding problems, stroke, blood clot problems, breast cancer, uterus/cervix/vaginal cancer.

The common side effects of GRAVION GRANULES 5GM include changes in weight, unwanted hair growth, menstrual disturbances, swelling over the body, fever, headache, and fatigue. Most of the side effects of GRAVION GRANULES 5GM do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.

Feeling depressed after taking GRAVION GRANULES 5GM is not a common side effect, but it may occur in some individuals due to hormonal changes. GRAVION GRANULES 5GM is a synthetic hormone that may cause fluctuations in certain hormone levels, leading to mood changes such as irritability, anxiety, and depression. If you continue to feel depressed, please consult your doctor.

Natural progesterone plays a key role in regulating the menstrual cycle (the monthly process in which a woman's body prepares for pregnancy), preparing the uterus for pregnancy, supporting early pregnancy, preventing lactation during pregnancy, and maintaining a healthy hormonal balance. It also helps reduce the risk of uterine cancer, promotes bone health, and supports mood stability.

Country of origin

India

Manufacturer/Marketer address

101-102 Aditya Tower, District Centre, Laxmi Nagar, Delhi : 110092, India
Other Info - GRA0179

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Author Details

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:49 AM IST

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Reference

  1. https://www.mims.com/india/drug/info/allylestrenol?type=full&mtype=generic
  2. https://www.researchgate.net/publication/322739835_Oral_Allylestrenol_A_Pregnancy-supporting_Progestogen
  3. https://www.lybrate.com/medicine/allylestrenol

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