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Written By Bayyarapu Mahesh Kumar , M Pharmacy

Gramoneg Oral Suspension is used to treat urinary tract infections (UTIs). It contains Nalidixic acid, which works by inhibiting the action of a bacterial enzyme that is essential for bacterial reproduction. In some cases, this medicine may cause side effects such as diarrhoea, dizziness, headache, nausea, or stomach pain. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Gramoneg Oral Suspension

Gramoneg Oral Suspension is used to treat urinary tract infections (UTIs) caused by bacteria. Urinary tract infection is the most common infection in humans caused by microbes. It can occur in any part of the urinary tract, such as the bladder, urethra, kidneys, or ureters.

Gramoneg Oral Suspension contains Nalixic acid, an antibiotic that works by inhibiting the action of DNA gyrase (a bacterial enzyme), which is essential for repairing and replicating bacteria's genetic material (DNA). Thus, it prevents the reproduction and repair of bacteria. Thus, it kills bacteria and clears the infection.

Take Gramoneg Oral Suspension as prescribed by your doctor. You are advised to take Gramoneg Oral Suspension for as long as your doctor has prescribed it for you based on your medical condition. Sometimes, you may experience diarrhoea, dizziness, headache, nausea, or stomach pain. Most of these side effects of Gramoneg Oral Suspension do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Please tell your doctor if you are allergic to Gramoneg Oral Suspension or any other medicines. If you are pregnant or planning for pregnancy, please inform your doctor before taking Gramoneg Oral Suspension. Avoid taking Gramoneg Oral Suspension if you are breastfeeding as it may be excreted in breastmilk and harm the baby. You are recommended to complete the full course of Gramoneg Oral Suspension as your doctor prescribes for effective results. You are advised to maintain a time gap of 2 hours between taking Gramoneg Oral Suspension and mineral supplements, vitamins with minerals or iron, sucralfate, didanosine, or antacids containing magnesium, calcium, and aluminium.

Uses of Gramoneg Oral Suspension

Gramoneg Oral Suspension is used to treat urinary tract infections. The detailed use of Gramoneg Oral Suspension is as follows:<br/>• Urinary Tract Infections (UTIs): Gramoneg Oral Suspension helps eliminate bacterial infections in the urinary system.<br/>

Directions for Use

• Gramoneg Oral Suspension can be taken with or without food as directed by the doctor. • Follow your doctor's instructions on the dosage and timing of this medication.• Use the measuring cup provided inthe pack to measure the prescribed dose and take it orally.• Shake the bottle well before each use.

Medicinal Benefits

Gramoneg Oral Suspension contains Nalidixic acid, which is a broad-spectrum antibiotic that acts against both gram-positive bacteria and gram-negative bacteria. It is mainly active against gram-negative bacteria such as E-coli, Klebsiella pneumoniae, Enterobacter species, Proteus mirabilis, Proteus vulgaris, Providencia rettgeri and Morganella morganii. Gramoneg Oral Suspension inhibits DNA gyrase (bacterial enzyme) action that is essential for repairing and replicating the genetic material (DNA) of bacteria. Thereby prevents reproduction and repair of bacteria. Thus, kills bacteria and clears the infection.

How Gramoneg Oral Suspension Works

Gramoneg Oral Suspension contains Nalixic acid, an antibiotic that works by inhibiting the action of DNA gyrase (a bacterial enzyme), which is essential for repairing and replicating bacteria's genetic material (DNA). Thus, it prevents the reproduction and repair of bacteria. Thus, it kills bacteria and clears the infection.

Storage

• Store in a cool and dry place away from sunlight.• Keep Gramoneg Oral Suspension out of reach and sight of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

If you are allergic to Gramoneg Oral Suspension or any other medicines, please tell your doctor. If you have fits, porphyria (disorder in the formation of red blood pigment), kidney or liver problems, inform your doctor before taking Gramoneg Oral Suspension. If you are pregnant or planning for pregnancy, please inform your doctor before taking Gramoneg Oral Suspension. Avoid taking Gramoneg Oral Suspension if you are breastfeeding as it may be excreted in breastmilk and harm the baby. You are recommended to drink plenty of water to flush out the bacteria. You are recommended to complete the full course of Gramoneg Oral Suspension as prescribed by your doctor for effective results. You are advised to maintain a time gap of 2 hours between taking Gramoneg Oral Suspension and mineral supplements, vitamins with minerals or iron, sucralfate, didanosine, or antacids containing magnesium, calcium, and aluminium.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Gramoneg Oral Suspension 30 ml:
Co-administration of Gramoneg Oral Suspension 30 ml with Cyclophosphamide may cause an increase in the risk of side effects.

How to manage the interaction:
Co-administration of Cyclophosphamide and Gramoneg Oral Suspension 30 ml can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like bruising or bleeding, unusual weakness, nausea, stomach pain, low fever, or loss of appetite, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Gramoneg Oral Suspension 30 ml:
Coadministration of Warfarin with Gramoneg Oral Suspension 30 ml can increase the risk of bleeding.

How to manage the interaction:
Although taking Gramoneg Oral Suspension 30 ml and Warfarin together can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not stop using any medications without consulting a doctor.
How does the drug interact with Gramoneg Oral Suspension 30 ml:
When Glimepiride is taken with Gramoneg Oral Suspension 30 ml, can sometimes affect blood glucose levels. Both hyperglycemia (high blood glucose) and, less frequently, hypoglycemia (low blood glucose) have been reported.

How to manage the interaction:
There may be a possibility of interaction between Glimepiride and Gramoneg Oral Suspension 30 ml, but it can be taken if prescribed by a doctor. It's important to monitor your blood sugar levels closely. If you experience symptoms like kidney problems, low or high blood sugar, or other concerning symptoms, contact a doctor right away. They may be able to suggest alternative medications that won't interact with a diabetes treatment. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Gramoneg Oral Suspension 30 ml:
Coadministration of Busulfan with Gramoneg Oral Suspension 30 ml can increase the risk of side effects.

How to manage the interaction:
Although there is a possible interaction between Busulfan and Gramoneg Oral Suspension 30 ml, you can take these medicines if prescribed by your doctor. Contact your doctor immediately if you notice unusual bruising, stomach discomfort, fever, or weakness. Do not stop using any medications without contacting your doctor.
How does the drug interact with Gramoneg Oral Suspension 30 ml:
Taking Gramoneg Oral Suspension 30 ml and hydrocortisone together can cause tendinitis and tendon rupture.

How to manage the interaction:
Co-administration of Gramoneg Oral Suspension 30 ml and hydrocortisone can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like pain, swelling, or inflammation of a tendon area such as the back of the ankle, shoulder, biceps, hand, or thumb, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Gramoneg Oral Suspension 30 ml:
Coadministration of repaglinide with Gramoneg Oral Suspension 30 ml can affect blood glucose levels. Both high blood glucose (hyperglycemia) and, to a lesser extent, low blood glucose (hypoglycemia).

How to manage the interaction:
Although taking Repaglinide together with Gramoneg Oral Suspension 30 ml can possibly result in an interaction, they can be taken together if prescribed by your doctor. Consult the doctor if you experience symptoms such as nervousness, confusion, headache, dizziness, drowsiness, tremors, nausea, hunger, weakness, perspiration, palpitation, rapid heartbeat, increased urination, increased thirst, and increased hunger. Maintaining blood glucose levels is advised. Do not stop using any medications without talking to a doctor.
How does the drug interact with Gramoneg Oral Suspension 30 ml:
Taking insulin aspart with Gramoneg Oral Suspension 30 ml affects blood glucose levels. Both hyperglycemia (high blood glucose) and, less frequently, hypoglycemia have been reported.

How to manage the interaction:
There could be a possible interaction between insulin aspart and Gramoneg Oral Suspension 30 ml but can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience symptoms of hypoglycemia, which include headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat, or symptoms of hyperglycemia which may include increased thirst, increased hunger, and increased urination. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Gramoneg Oral Suspension 30 ml:
Co-administration of Gramoneg Oral Suspension 30 ml with Melphalan together can increase the risk or severity of side effects.

How to manage the interaction:
Although taking Melphalan and Gramoneg Oral Suspension 30 ml together can evidently cause an interaction, it can be taken if your doctor has suggested it. However contact a doctor immediately, if you experience any symptoms such as easy bruising or bleeding, unusual weakness, nausea, stomach pain, low fever, or loss of appetite. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Gramoneg Oral Suspension 30 ml:
Taking isophane insulin with Gramoneg Oral Suspension 30 ml affects blood glucose levels, which may cause hyperglycemia (high blood sugar) and hypoglycemia (low blood sugar) less frequently.

How to manage the interaction:
Although taking Gramoneg Oral Suspension 30 ml and Isophane Insulin together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience hypoglycemia or hyperglycemia. Symptoms of hypoglycemia include headache, dizziness, drowsiness, nervousness, confusion, shaking, nausea, loss of hunger, weakness, sweating, palpitations, and rapid heartbeat. Symptoms of hyperglycemia may include increased thirst, increased hunger, and increased urination. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Gramoneg Oral Suspension 30 ml:
Taking insulin glulisine with Gramoneg Oral Suspension 30 ml affects blood glucose levels, which may cause hyperglycemia (high blood sugar) and hypoglycemia (low blood sugar) less frequently.

How to manage the interaction:
Although taking Gramoneg Oral Suspension 30 ml and Insulin glulisine together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience hypoglycemia or hyperglycemia. Symptoms of hypoglycemia include headache, dizziness, drowsiness, nervousness, confusion, shaking, nausea, loss of hunger, weakness, sweating, palpitations, and rapid heartbeat. Symptoms of hyperglycemia may include increased thirst, increased hunger, and increased urination. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid alcohol, soda, coffee, tea, and artificial sweeteners, as they may cause bladder irritation.
  • Drink plenty of water or other fluids daily while taking Gramoneg Oral Suspension to flush out the bacteria.
  • Avoid spicy foods and citrus fruits (lemons, oranges, grapefruits) as they may irritate the bladder.
  • Eat foods antioxidant-rich foods such as blueberries, cranberries, tomatoes, spinach, broccoli, and plain Greek yoghurt.
  • Take probiotics after completing the entire course of Gramoneg Oral Suspension to restore some good bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like cheese, yoghurt, kombucha, sauerkraut, and kimchi can restore the good bacteria of the intestine.
  • Include fibre-rich foods, which can be easily digested by your gut bacteria and help stimulate their growth. Thus, fibre-rich foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains such as brown rice and whole-grain bread should be included in your diet.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS
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Alcohol

Caution

The interaction of alcohol with Gramoneg Oral Suspension is unknown. Please consult a doctor before consuming alcohol while using Gramoneg Oral Suspension.

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Pregnancy

Caution

Gramoneg Oral Suspension is a category C pregnancy drug and is given to pregnant women only if the doctor thinks benefits outweigh risks. Please consult a doctor if you are pregnant.

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Breast Feeding

Unsafe

Gramoneg Oral Suspension is not recommended for breastfeeding mothers as it may be excreted in breastmilk. Please consult a doctor if you are breastfeeding.

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Driving

Safe if prescribed

Gramoneg Oral Suspension usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Take Gramoneg Oral Suspension with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Gramoneg Oral Suspension with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Gramoneg Oral Suspension is not recommended for infants below 3 months, as the safety and effectiveness were not established. However, Gramoneg Oral Suspension should be used in children below 18 years if prescribed by a doctor only.

Have a query?

FAQs

Gramoneg Oral Suspension is used to treat urinary tract infections (UTIs) caused by bacteria.

Gramoneg Oral Suspension contains Nalidixic acid, an antibiotic that works by inhibiting the action of DNA gyrase (bacterial enzyme) that is essential for repairing and replicating the genetic material (DNA) of bacteria. Thereby prevents reproduction and repair of bacteria. Thus, kills bacteria and clears the infection.

Gramoneg Oral Suspension may cause diarrhoea as a temporary adverse effect. However, if the condition persists or worsens or notices blood in stools, please consult your doctor.

You are not recommended to take Gramoneg Oral Suspension with probenecid as co-administration of these medicines may reduce the effectiveness of Gramoneg Oral Suspension and increase its adverse effects. However, please consult your doctor before taking Gramoneg Oral Suspension with other medicines.

Gramoneg Oral Suspension is not used to treat viral infections. Gramoneg Oral Suspension is an antibiotic that kills bacteria and is used to treat only bacterial infections.

You are not recommended to stop taking Gramoneg Oral Suspension without consulting your doctor as it may worsen the infection or cause recurring symptoms. Therefore, take Gramoneg Oral Suspension for as long as your doctor has prescribed it, and if you experience any difficulty while taking Gramoneg Oral Suspension, please consult your doctor.

You are not recommended to take Gramoneg Oral Suspension with warfarin as it may increase the risk of bleeding more easily. However, please consult a doctor before using Gramoneg Oral Suspension with other medicines to adjust the dose appropriately to use both medicines safely.

Country of origin

India

Manufacturer/Marketer address

SUN HOUSE, CTS No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Other Info - GRA0006

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