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  3. Gliotem 250 Capsule 1's

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Gliotem 250 Capsule 1's, Pack of 1 Capsule
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Gliotem 250 Capsule is an anti-cancer medicine used in the treatment of brain tumours such as glioblastoma multiforme (a type of tumour that grows and spreads rapidly) in adults and malignant glioma, including glioblastoma multiforme or anaplastic astrocytoma. This medicine works by inhibiting the production of DNA (deoxyribonucleic acid-genetic material of the cell), thereby affecting cell growth and division. Common side effects include loss of appetite, anxiety, confusion, headache, vomiting, nausea, diarrhoea, constipation, muscle weakness, muscle aches, and fever.
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Composition :

TEMOZOLOMIDE-250MG

Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Gliotem 250 Capsule

Gliotem 250 Capsule belongs to a class of medicines called 'anti-cancer/ antitumor agent', used to treat specific forms of brain tumours such as glioblastoma multiforme (a type of tumour that grows and spreads rapidly) in adults and malignant glioma, including glioblastoma multiforme or anaplastic astrocytoma (a rare malignant brain tumour) in patients older than 3years. A brain tumour is an uncontrolled and unregulated proliferation of cells in the brain. 

Gliotem 250 Capsule contains Temozolomide which works by inhibiting the production of DNA (deoxyribonucleic acid-genetic material of the cell), thereby affecting cell growth and division. Thus, Gliotem 250 Capsule prevents tumours from growing.

Take Gliotem 250 Capsule as prescribed. In some cases, Gliotem 250 Capsule may cause loss of appetite, anxiety, confusion, headache, vomiting, nausea, diarrhoea, constipation, muscle weakness, muscle aches, and fever. Most of these side effects of Gliotem 250 Capsule do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Let your doctor know if you are allergic to any of the contents. Gliotem 250 Capsule is not recommended for patients with severe bone marrow depression or significant bleeding. Avoid taking Gliotem 250 Capsule if you are pregnant or breastfeeding. Both women and men using Gliotem 250 Capsule should use birth control to avoid pregnancy and fathering a child. It would be best not to drive and/or operate machines that require alertness as Gliotem 250 Capsule may cause tiredness or sleepiness.

Uses of Gliotem 250 Capsule

Treatment of Brain tumour

Have a query?

Directions for Use

• Gliotem 250 Capsule can be taken with or without food, or as directed by your doctor. To minimize potential side effects like nausea and vomiting, it is recommended to take Gliotem 250 Capsule consistently either on an empty stomach or with meals.• Gliotem 250 Capsule is usually taken once daily; however, follow your doctor's instructions regarding dosage and timing to ensure optimal effectiveness.• Swallow Gliotem 250 Capsule as a whole with a glass of water.• Do not crush, chew, or break Gliotem 250 Capsule, as this may impact absorption.

Medicinal Benefits

Gliotem 250 Capsule belongs to a class of medicines called anti-cancer/antitumor agents used to treat specific forms of brain tumours such as glioblastoma multiforme (a type of tumour that grows and spreads rapidly) in adults and malignant glioma, including glioblastoma multiforme or anaplastic astrocytoma (a rare malignant brain tumour) in patients older than 3years. It contains Temozolomide which works by binding to the DNA (deoxyribonucleic acid-genetic material of the cell) and interfering with cell growth and division. Thus, Gliotem 250 Capsule prevents tumours from growing.

How Gliotem 250 Capsule Works

Gliotem 250 Capsule contains Temozolomide which works by inhibiting the production of DNA (deoxyribonucleic acid-genetic material of the cell), thereby affecting cell growth and division. Thus, Gliotem 250 Capsule prevents tumours from growing.

Storage

• Store in a cool and dry place away from sunlight.• Keep Gliotem 250 Capsule out of the sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Gliotem 250 Capsule
  • Eat protein-rich foods like fish, poultry, eggs, and legumes.
  • Include foods with minerals and vitamins essential for hair health.
  • Join a support group to connect with others experiencing hair loss.
  • Openly discuss your feelings about hair loss.
  • Consider covering up with wigs, hats, or scarves.
  • Be patient and avoid seeking miracle cures.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • Wear compression garments like stockings, sleeves, or gloves to apply pressure and help stop fluid from building up, especially after the swelling goes down.
  • Move around and do exercises to help the fluid circulate, especially in swollen limbs. Ask your doctor for specific exercises.
  • Raise the swollen area above your heart level several times a day, even while sleeping, to help reduce swelling.
  • Gently massage the swollen area with firm but not painful pressure.
  • Keep the swollen area clean and moisturized to prevent injury and infection.
  • Reduce salt intake to help prevent fluid from building up and worsening the swelling, as advised by a doctor.
  • If the swelling does not get better after a few days of home treatment or worsens, consult your doctor right away.
  • Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
  • Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
  • Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
  • Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
  • If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
  • In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
  • Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
  • If you experience severe bleeding or bruising, seek emergency medical attention immediately.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

What if I have taken an overdose of Gliotem 250 Capsule

Do not take more than the prescribed dose of Gliotem 250 Capsule as it may cause overdose. The symptoms of overdose include unusual bleeding or bruising; red/black/tarry stools; red/dark brown/pink urine; coughing up or vomiting blood or material that looks like coffee grounds; sore throat, fever, ongoing congestion and cough, or other signs of infection. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Gliotem 250 Capsule should be taken under strict medical supervision. The doctor will regularly monitor your condition while taking Gliotem 250 Capsule. To treat your condition effectually, continue taking Gliotem 250 Capsule for as long as your doctor has prescribed. Do not stop Gliotem 250 Capsule midway under any circumstances without consulting the healthcare professional. Inform your doctor if you have an allergy to any components of Gliotem 250 Capsule. Inform your doctor before taking Gliotem 250 Capsule if you have allergic reactions, infections, lung, renal or hepatic disorders or low blood count (including neutropenia, lymphopenia, thrombocytopenia). Gliotem 250 Capsule is not recommended for patients with severe bone marrow depression or significant bleeding. Avoid taking Gliotem 250 Capsule if you are pregnant or breastfeeding. Both women and men using Gliotem 250 Capsule should use birth control to avoid pregnancy or fathering a child. Do not receive any vaccinations or immunizations without your doctor's approval while taking Gliotem 250 Capsule.

Drug-Drug Interactions

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TemozolomideClozapine
Severe
TemozolomideVoclosporin
Severe

Drug-Drug Interactions

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TemozolomideClozapine
Severe
How does the drug interact with Gliotem 250 Capsule:
Taking Gliotem 250 Capsule with clozapine may increase the risk of serious infections.

How to manage the interaction:
Although taking Gliotem 250 Capsule and clozapine together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting doctor.
TemozolomideVoclosporin
Severe
How does the drug interact with Gliotem 250 Capsule:
Taking voclosporin with Gliotem 250 Capsule, may increase the risk of serious infections.

How to manage the interaction:
Although taking Gliotem 250 Capsule and voclosporin together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting doctor.
TemozolomideThalidomide
Severe
How does the drug interact with Gliotem 250 Capsule:
Taking thalidomide with Gliotem 250 Capsule can increase the risk of blood clots.

How to manage the interaction:
Although taking Gliotem 250 Capsule and thalidomide together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, and/or pain, redness or swelling in an arm or leg. Do not stop using any medications without consulting doctor.
TemozolomideBaricitinib
Severe
How does the drug interact with Gliotem 250 Capsule:
Taking baricitinib and Gliotem 250 Capsule can increase the risk of developing serious infections.

How to manage the interaction:
Although there is an interaction, baricitinib can be taken with Gliotem 250 Capsule if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in your coughing fluid, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without talking to a doctor.
TemozolomideAdalimumab
Severe
How does the drug interact with Gliotem 250 Capsule:
Using adalimumab together with Gliotem 250 Capsule may increase the risk of serious infections.

How to manage the interaction:
Although taking Gliotem 250 Capsule and adalimumab together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting doctor.
TemozolomideLeflunomide
Severe
How does the drug interact with Gliotem 250 Capsule:
Taking Gliotem 250 Capsule with Leflunomide can increase the risk of infections.

How to manage the interaction:
Although taking Gliotem 250 Capsule and leflunomide together can result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, red or inflamed skin, body sores, pain or burning during urination, vomiting, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes. Do not stop using any medications without consulting a doctor.
TemozolomideCladribine
Severe
How does the drug interact with Gliotem 250 Capsule:
Using cladribine together with Gliotem 250 Capsule may increase the risk of serious infections.

How to manage the interaction:
Although taking Gliotem 250 Capsule and cladribine together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting doctor.
TemozolomideEtanercept
Severe
How does the drug interact with Gliotem 250 Capsule:
Taking Gliotem 250 Capsule with Etanercept can increase the risk of infections.

How to manage the interaction:
Although taking Gliotem 250 Capsule and etanercept together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting doctor.
TemozolomideFingolimod
Severe
How does the drug interact with Gliotem 250 Capsule:
Taking Gliotem 250 Capsule with Fingolimod can increase the risk of infection.

How to manage the interaction:
Although taking Gliotem 250 Capsule and fingolimod together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting doctor.
TemozolomideInfliximab
Severe
How does the drug interact with Gliotem 250 Capsule:
Taking Gliotem 250 Capsule with Infliximab can increase the risk of infections.

How to manage the interaction:
Although taking Gliotem 250 Capsule and infliximab together can result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Performing yoga may also help in improving both physical and mental health.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs in your diet.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugars.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

Gliotem 250 Capsule Substitute

Substitutes safety advice
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Alcohol

Caution

You are recommended to avoid alcohol consumption while taking Gliotem 250 Capsule. It could lead to unpleasant side effects.

bannner image

Pregnancy

Caution

Please consult your doctor if you have any concerns about this. Gliotem 250 Capsule should not be used during pregnancy unless prescribed by your doctor. Women of childbearing potential must use effective contraception during the treatment and for 6months after completion of the treatment.

bannner image

Breast Feeding

Unsafe

Gliotem 250 Capsule should not be taken during breastfeeding as it passes into the breastmilk and may harm the baby.

bannner image

Driving

Caution

Gliotem 250 Capsule may make you feel tired or sleepy. Drive and/or operate machines only if you are alert.

bannner image

Liver

Caution

If you have had a history or evidence of any liver-related diseases, please consult the doctor before using Gliotem 250 Capsule. Your doctor will weigh the benefits and potential risks before prescribing Gliotem 250 Capsule.

bannner image

Kidney

Caution

If you have had a history or evidence of any kidney-related diseases, please consult the doctor before using Gliotem 250 Capsule. Your doctor will weigh the benefits and potential risks before prescribing Gliotem 250 Capsule.

bannner image

Children

Caution

Safety and effectiveness of Gliotem 250 Capsule in paediatric patients under the age of three have not been established.

FAQs

Gliotem 250 Capsule belongs to a class of medicines called anti-cancer agents, used to treat specific forms of brain tumours such as glioblastoma multiforme (a type of tumour that grows and spreads rapidly) in adults and malignant glioma, including glioblastoma multiforme or anaplastic astrocytoma (a rare malignant brain tumour) in patients older than 3years.

Gliotem 250 Capsule works by binding to the DNA (deoxyribonucleic acid-genetic material of the cell) and interfering with cell growth and division. Thus, Gliotem 250 Capsule prevents tumours from growing.

Gliotem 250 Capsule may cause permanent infertility. Male patients should use effective contraception and refrain from fathering a child for up to three months after treatment is completed. Prior to treatment, it is recommended to seek sperm conservation advice from your doctor.

Yes, Gliotem 250 Capsule can cause neutropenia (low white blood cells count), lymphopenia (low lymphocytes count), thrombocytopenia (low platelet count). As a part of therapy, your doctor may monitor your blood profile.

Gliotem 250 Capsule may lead to hyperglycemia (Increased blood sugar). Consult your doctor if you are diabetic. Regularly monitor your blood sugar levels while taking Gliotem 250 Capsule.

The live vaccine may interact with Gliotem 250 Capsule. Do not have vaccinations or immunisations without talking to your doctor first.

Country of origin

India

Manufacturer/Marketer address

Plot No 107/108,Namli Block , Ranipool, East Sikkim 737135
Other Info - GLI1847

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Santoshini Reddy GDoctor badge

Reviewed By

Santoshini Reddy G

M Pharmacy

Last Updated

Jul 18, 2025 | 6:56 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/021029s031lbl.pdf
  2. https://www.uhs.nhs.uk/Media/UHS-website-2019/Docs/Chemotherapy-SOPs1/CNS/Temozolomide-150.pdf
  3. https://www.medicines.org.uk/emc/product/5312/smpc#gref
  4. https://www.drugs.com/drug-interactions/temozolomide-index.html

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