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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Glimibay 2 mg Tablet is used to treat type 2 diabetes. It contains Glimepiride and Metformin, which work by decreasing the amount of glucose absorbed from the food and the amount of glucose made by the liver. It helps the pancreas produce insulin and enables the body to use it efficiently. In some cases, this medicine may cause side effects such as stomach pain, nausea, diarrhoea, vomiting, headache or a metallic taste. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Whats That

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Synonym :

GLIMEPIRIDE+METFORMIN HYDROCHLORIDE

Manufacturer/Marketer :

Ellora Pharmaceutical

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About Glimibay 2 mg Tablet

Glimibay 2 mg Tablet belongs to a class of medicines called anti-diabetic drugs used in the treatment of type 2 diabetes, especially in patients whose blood sugar levels are not controlled by diet and exercise alone.

Glimibay 2 mg Tablet contains Glimepiride and Metformin. Glimepiride helps the pancreas release more insulin, thereby lowering blood sugar levels. Metformin reduces the amount of sugar produced by the liver, slows down sugar absorption from food, and helps the body use insulin more effectively.

In some cases, Glimibay 2 mg Tablet may cause side effects like stomach pain, nausea, diarrhoea, vomiting, headache or metallic taste. Most of these side effects of Glimibay 2 mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Do not take Glimibay 2 mg Tablet if you are allergic to any of its components. Glimibay 2 mg Tablet is not recommended during pregnancy, breastfeeding and in children. Avoid alcohol consumption with Glimibay 2 mg Tablet as it may increase the risk of lactic acidosis (accumulation of lactic acid in the body).

Uses of Glimibay 2 mg Tablet

Glimibay 2 mg Tablet is used in the treatment of type 2 diabetes mellitus. The detailed uses of Glimibay 2 mg Tablet are as follows:<br/>• Management of Type 2 Diabetes: Glimibay 2 mg Tablet helps lower blood sugar levels in individuals diagnosed with type 2 diabetes.<br/>• Improvement of Insulin Sensitivity: Glimibay 2 mg Tablet enhances the action of insulin, making the body's tissues more responsive to it.<br/>• Reduction of Cardiovascular Risks: Regular use of Glimibay 2 mg Tablet can help reduce the risk of cardiovascular diseases in diabetic patients.<br/>• Control of Blood Sugar Levels Post Meals: Glimibay 2 mg Tablet assists in lowering postprandial blood sugar spikes, which is beneficial for overall diabetes management.<br/>

Directions for Use

  • Glimibay 2 mg Tablet can be taken with meals or as prescribed by the doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow Glimibay 2 mg Tablet as a whole with a glass of water.
  • Do not chew, crush or break it.

Medicinal Benefits

  • Glimibay 2 mg Tablet is indicated as an adjunct to diet and exercise to improve glycaemic control in patients with type 2 diabetes.
  • It helps manage blood glucose levels in patients with diabetes and prevents diabetes-related complications like kidney damage, eye problems, and nerve issues.
  • Glimibay 2 mg Tablet contains Glimepiride and Metformin, which work together to offer a dual-action approach for effectively managing type 2 diabetes.
  • Glimepiride stimulates cells in the pancreas that produce insulin, which helps remove sugar from the blood.
  • Metformin reduces sugar production by cells in the liver and delays sugar absorption from the intestines. Additionally, it enhances the sensitivity of muscle cells to insulin, allowing these cells to remove sugar more effectively from the bloodstream.

How Glimibay 2 mg Tablet Works

Glimibay 2 mg Tablet is a combination of two antidiabetic drugs, namely: Glimepiride and Metformin. Glimepiride works by stimulating beta cells in the pancreas that produce insulin. Thus, insulin helps to remove sugar from the blood. Metformin works by reducing the sugar production by cells in the liver and delays sugar absorption from the intestines. Also, it increases the sensitivity of muscle cells to insulin, which enables these cells to remove sugar more effectively from the blood.

Storage

Keep Glimibay 2 mg Tablet out of reach and sight of children.
Side effects of Glimibay 2 mg Tablet
  • If you experience low blood sugar levels, inform your doctor. They will assess the severity and make recommendations for the next actions.
  • Your doctor will assess your symptoms, blood sugar levels, and overall health before recommending the best course of action, which may include treatment, lifestyle modifications, or prescription adjustments.
  • Follow your doctor's instructions carefully to manage the episode and adjust your treatment plan.
  • Make medication adjustments as recommended by your doctor to prevent future episodes.
  • Implement diet and lifestyle modifications as your doctor advises to manage low blood sugar levels.
  • Monitor your blood sugar levels closely for patterns and changes.
  • Track your progress by recording your blood sugar levels, food intake, and physical activity.
  • Seek further guidance from your doctor if symptoms persist or worsen so that your treatment plan can be revised.
  • Get plenty of rest and sleep.
  • Keep your body warm.
  • Drink plenty of fluids to stay hydrated.
  • Avoid strenuous activities.
  • Maintain good hygiene to prevent flu from spreading.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

What if I have taken an overdose of Glimibay 2 mg Tablet

Take Glimibay 2 mg Tablet only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include hypoglycaemia (low blood sugar) and lactic acidosis (buildup of lactic acid in the blood). If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

  • Do not take Glimibay 2 mg Tablet if you are allergic to any of its components, if you have type 1 diabetes mellitus, diabetic ketoacidosis or diabetic coma. 
  • Inform the doctor if you have liver or kidney problems, low blood sugar, or circulation problems.
  • Glimibay 2 mg Tablet is not recommended for pregnant women as it may harm the unborn baby. Please consult a doctor if you are pregnant or planning to become pregnant. This medicine may pass into breast milk; therefore, it should be avoided in nursing mothers. 
  • Glimibay 2 mg Tablet may decrease alertness in some people. Therefore, drive only if you are alert after taking Glimibay 2 mg Tablet . 
  • Avoid alcohol consumption with Glimibay 2 mg Tablet as it may increase the risk of lactic acidosis (accumulation of lactic acid in the body).
  • Beware of symptoms of hypoglycemia (low blood sugar), which include sweating, dizziness, palpitations, shivering, intense thirst, dry mouth, dry skin, frequent urination, etc. Whenever you experience any of these symptoms, immediately consume candies, glucose biscuits, or honey/sugar. Make sure to carry these with you at all times, especially during long travels.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Glimibay 2 mg Tablet:
Co-administration of Sparfloxacin with Glimibay 2 mg Tablet can affect blood glucose levels. Both high blood glucose and, less frequently, low blood glucose have been reported.

How to manage the interaction:
Although there is a possible interaction, Glimibay 2 mg Tablet can be taken with Sparfloxacin if prescribed by the doctor. Consult the prescriber if you experience symptoms of low blood sugar such as headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat (or) symptoms of high blood sugar like increased thirst, increased hunger, and increased urination. Monitoring of blood glucose levels is advised. Do not discontinue the medications without consulting a doctor.
How does the drug interact with Glimibay 2 mg Tablet:
Taking Glimibay 2 mg Tablet with Gatifloxacin may affect blood glucose levels. Both low blood glucose and, less frequently, high blood glucose have been reported.

How to manage the interaction:
Gatifloxacin is not recommended for patients with diabetes, however, it can be taken if advised by a doctor. Consult the prescriber if you experience symptoms such as nervousness, confusion, headache, dizziness, drowsiness, tremors, nausea, hunger, weakness, perspiration, palpitation, rapid heartbeat, increased urination, increased thirst, and increased hunger. Maintaining blood glucose levels is advised. Do not discontinue the medications without consulting a doctor.
How does the drug interact with Glimibay 2 mg Tablet:
Co-administration of Leflunomide may increase the blood levels and effects of Glimibay 2 mg Tablet.

How to manage the interaction:
Although there is a possible interaction, Glimibay 2 mg Tablet can be taken with Leflunomide if prescribed by the doctor. Consult the doctor if your condition changes or you experience increased side effects. Regular monitoring of blood glucose levels is advised. Do not discontinue the medications without consulting a doctor.
How does the drug interact with Glimibay 2 mg Tablet:
Taking Glimibay 2 mg Tablet with Sulfadiazine may increase the risk of low blood sugar.

How to manage the interaction:
Although there is a possible interaction, Glimibay 2 mg Tablet can be taken with sulfadiazine if prescribed by the doctor. Consult the prescriber if you experience symptoms of low blood sugar such as headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat. Do not discontinue the medications without consulting a doctor. Do not discontinue the medications without consulting a doctor.
How does the drug interact with Glimibay 2 mg Tablet:
Taking Glimibay 2 mg Tablet with Vilazodone may increase the risk of low blood sugar.

How to manage the interaction:
Although there is a possible interaction, Glimibay 2 mg Tablet can be taken with Vilazodone if prescribed by the doctor. Consult the prescriber if you experience symptoms of low blood sugar such as headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat. Do not discontinue the medications without consulting a doctor.
How does the drug interact with Glimibay 2 mg Tablet:
Taking Glimibay 2 mg Tablet with Sibutramine may lose the weight and may leads to hypoglycemia sometimes.

How to manage the interaction:
Although there is a possible interaction, Glimibay 2 mg Tablet can be taken with sibutramine if prescribed by the doctor. The doctor may advise frequent monitoring of a blood sugar and adjustment of your diabetic regimen both during and after treatment with sibutramine. Let the doctor know if you experience symptoms of low blood glucose such as headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat. Do not discontinue the medications without consulting a doctor.
How does the drug interact with Glimibay 2 mg Tablet:
Taking Glimibay 2 mg Tablet with sunitinib may increase the risk of low blood sugar.

How to manage the interaction:
Although there is a possible interaction, Glimibay 2 mg Tablet can be taken with sunitinib if prescribed by the doctor. Consult the prescriber if you experience symptoms if low blood sugar such as headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat. Do not discontinue the medications without consulting a doctor.
GlimepirideGrepafloxacin
Severe
How does the drug interact with Glimibay 2 mg Tablet:
Co-administration of Glimibay 2 mg Tablet with Grepafloxacin can sometimes affect blood glucose levels. Both hyperglycemia (high blood glucose) and, less frequently, hypoglycemia (low blood glucose) have been reported.

How to manage the interaction:
Although there is a possible interaction between Glimibay 2 mg Tablet and Grepafloxacin, you can take these medicines together if prescribed by a doctor. If you experience any of these symptoms - low blood sugar, headache, dizziness, sleepiness, confusion, shaking, feeling hungry, weak, heart racing, high blood sugar, low blood sugar, serious infections, bleeding, feeling anxious, feeling sick or very thirsty - make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
GlimepirideAmprenavir
Severe
How does the drug interact with Glimibay 2 mg Tablet:
Co-administration of Amprenavir and Glimibay 2 mg Tablet may interfere with blood glucose control and reduce the effectiveness of Glimibay 2 mg Tablet.

How to manage the interaction:
Although taking Glimibay 2 mg Tablet and Amprenavir together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you notice any of these signs - really high or low blood sugar levels - make sure to contact a doctor right away. Do not stop using any medications without a doctor's advice.
How does the drug interact with Glimibay 2 mg Tablet:
Co-administration of Miconazole with Glimibay 2 mg Tablet may increase the blood levels and effects of Glimibay 2 mg Tablet leading to low blood glucose levels.

How to manage the interaction:
Although there is a possible interaction between Miconazole and Glimibay 2 mg Tablet, you can take these medicines together if prescribed by a doctor. However, if you experience any symptoms such as headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat Consult a doctor immediately. Do not stop using medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Do regular exercise such as cycling, walking, jogging, dancing, or swimming for a minimum of 30 minutes per day. Invest at least 150 minutes of your week in exercise.
  • Maintain a healthy body weight, as obesity is also related to the onset of diabetes.
  • Maintain a low-fat and low-sugar diet. Replace carbohydrate-containing foods with whole grains, fruits, and vegetables, as carbohydrates turn to sugars, leading to high blood sugar.
  • Avoid the consumption of alcohol and quit smoking.

Habit Forming

No

Therapeutic Class

ANTIDIABETICS
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Alcohol

Unsafe

You are recommended to avoid consumption of alcohol with Glimibay 2 mg Tablet as it may increase the risk of lactic acidosis (accumulation of lactic acid in the body).

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Pregnancy

Unsafe

Glimibay 2 mg Tablet is not recommended for pregnant women as it may harm the unborn baby. Please consult a doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Glimibay 2 mg Tablet as it may be excreted in breastmilk and cause adverse effects in the baby. Therefore, please consult a doctor before using Glimibay 2 mg Tablet if you are breastfeeding.

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Driving

Caution

Glimibay 2 mg Tablet may decrease alertness in some people. Therefore, drive only if you are alert after taking Glimibay 2 mg Tablet .

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Liver

Caution

Take Glimibay 2 mg Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Glimibay 2 mg Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Glimibay 2 mg Tablet is not recommended for children as the safety and effectiveness were not established.

Have a query?

FAQs

Glimibay 2 mg Tablet is indicated in the treatment of type 2 diabetes mellitus.

Glimibay 2 mg Tablet works by decreasing the amount of glucose absorbed from the food and the amount of glucose made by the liver. It helps the pancreas to produce insulin and helps the body use insulin efficiently.

Glimibay 2 mg Tablet may increase the risk of low blood sugar levels, especially with alcohol intake, exercise more than usual, delay or miss snacks or meals. However, if you experience any signs of low blood pressure, such as dizziness, nausea, light-headedness, dehydration or fainting, please consult a doctor.

In type 1 diabetes, the body does not produce insulin as the islet cells (insulin-producing cells) in the pancreas are destroyed completely. In type 2 diabetes, though islet cells are working, the body doesn't respond to insulin as the body becomes resistant to it.

You are not recommended to stop taking Glimibay 2 mg Tablet on your own as discontinuing Glimibay 2 mg Tablet suddenly may cause recurring symptoms or worsen the condition. However, if you experience any difficulty while taking Glimibay 2 mg Tablet , please consult your doctor so that alternative medicine may be prescribed.

You are not recommended to take Glimibay 2 mg Tablet with phenytoin as it may reduce the effect of Glimibay 2 mg Tablet and increase blood sugar levels. However, please consult a doctor before using Glimibay 2 mg Tablet with other medicines.

Include a diet rich in fruits, vegetables and whole grains like brown rice, whole wheat, oats, barley, and quinoa. Non-fat or low-fat dairy and proteins like chicken, lean meats, nuts, beans, tofu, lentils, eggs, fish, and turkey can also be included.

Cut back on foods high in sodium, alcohol, fried foods, and high-carb food and drinks like sugary drinks, drinks with added sugar, white rice and starchy vegetables.

You are advised to take Glimibay 2 mg Tablet for the duration recommended by the doctor.

Store Glimibay 2 mg Tablet at room temperature, in a dry place. Keep out of sight and reach of children.

Glimibay 2 mg Tablet may cause lactic acidosis (builds up of lactic acid in the blood). Consult the doctor if you notice symptoms of lactic acidosis like abdominal pain, vomiting, muscle cramps, difficulty breathing, reduced body temperature and heartbeat, and severe tiredness.

Glimibay 2 mg Tablet is an anti-diabetic medicine used to treat type 2 diabetes mellitus, also known as noninsulin-dependent diabetes mellitus.

Side effects of Glimibay 2 mg Tablet are stomach pain, nausea, diarrhoea, vomiting, headache or metallic taste. Most of these side effects may not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Long-term use of Glimibay 2 mg Tablet may lead to vitamin B12 deficiency. Regular monitoring of vitamin B12 levels is recommended.

You are recommended to avoid consumption of alcohol with Glimibay 2 mg Tablet as it may increase the risk of lactic acidosis (accumulation of lactic acid in the body).

Glimibay 2 mg Tablet should be swallowed as a whole with water; do not crush, break or chew it.

Regularly monitor blood glucose levels. Have your meals regularly and never miss a meal. Always carry a source of sugar and consume it if you experience low blood sugar. If you are due to undergo any tests or surgery, inform the doctor that you are taking Glimibay 2 mg Tablet . Avoid drinking alcohol.

Other medicines should be taken with Glimibay 2 mg Tablet only if prescribed by the doctor. To prevent any interactions it is advised to consult the doctor before taking other medicines during treatment with Glimibay 2 mg Tablet .

Country of origin

India

Manufacturer/Marketer address

Thanjavur, India, 613004
Other Info - GLI0348

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