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compositionComposition:AMPICILLIN-500MG
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Gercillin 500 Injection is commonly used to treat various bacterial infections. It contains ampicillin, which works against multiple types of bacteria. It inhibits the process of bacterial cell wall synthesis, which is essential for the survival of bacteria. Thus, it kills bacteria and prevents the growth of bacterial infection. Common side effects of Gercillin 500 Injection are injection site reactions, rash, vomiting, allergic reaction, vaginal itching or discharge, nausea, and diarrhoea.

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Written By Dr. Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

AMPICILLIN-500MG

Manufacturer/Marketer :

Zydus Cadila

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

NPPA :

Regulated

About Gercillin 500 Injection

Gercillin 500 Injection is an injectable antibiotic used to treat a wide variety of severe bacterial infections. Doctors typically prescribe Gercillin 500 Injection for serious conditions, such as meningitis, blood infections, and infections of the heart, lungs, or urinary tract.

Because Gercillin 500 Injection is given as an injection, it is typically received at regular intervals throughout the day to keep a steady level in your body. It is injected directly into a vein or muscle, meaning food intake does not affect how well it works. Staying well-hydrated and prioritizing rest can significantly support your body's natural recovery during your treatment course.

While using Gercillin 500 Injection, you may experience mild side effects like swelling at the injection site or mild nausea. However, you must consult your doctor immediately if you develop severe watery diarrhea, skin rashes, or difficulty breathing.

Before starting treatment, tell your healthcare provider if you have kidney disease, asthma, or a history of allergies, especially to penicillin antibiotics. Do not take this if you have had a severe allergic reaction to penicillin or similar antibiotics in the past.

Some medicines, such as gout treatments or other antibiotics, can interfere with how Gercillin 500 Injection works or increase the risk of side effects. If you are pregnant, breastfeeding, or managing health conditions as an older adult, talk to your doctor or pharmacist to ensure this treatment is safe for you.

Uses of Gercillin 500 Injection

Gercillin 500 Injection is used in the treatment of Bacterial infections. The detailed uses of Gercillin 500 Injection are as follows:

  • Severe bacterial infections: Gercillin 500 Injection helps treat life-threatening bacterial infections in the blood (septicemia) by stopping the growth of bacteria.
  • Meningitis: It targets bacteria causing dangerous swelling and inflammation around the brain and spinal cord.
  • Endocarditis: It treats bacterial infections affecting the heart valves and inner heart lining.
  • Respiratory tract infections: It helps clear severe bacterial infections in the lungs, such as severe pneumonia.
  • Urinary tract infections (UTIs): It eliminates complicated bacterial infections affecting the kidneys or bladder.
     

Key Benefits

Gercillin 500 Injection helps treat bacterial infections by eliminating the bacteria responsible for the illness. When administered by a healthcare professional, it provides effective treatment and supports a faster recovery.

Benefits may include:

  • Helps treat susceptible bacterial infections throughout the body.
  • May provide rapid antibacterial action when given by injection.
  • Helps relieve symptoms such as fever, body aches, and fatigue as the infection improves.
  • Supports faster recovery and helps restore strength and overall well-being.
  • Helps prevent the infection from spreading or becoming more severe when used as prescribed.
  • Supports complete recovery when the full course of treatment is completed.
Side effects of Gercillin 500 Injection
Managing Medication-Triggered Thrombophlebitis (Inflammation of a vein): A Step-by-Step Guide:
  • If you have symptoms such as pain, swelling, redness, or warmth in your veins after taking medication, contact your doctor right once. Share information about your symptoms, medication regimen, and medical history.
  • Your doctor will then assess your medication regimen to determine if it's contributing to the thrombophlebitis. This assessment will help identify the best course of action to manage your condition and prevent further complications.
  • Your doctor may suggest certain diet and lifestyle changes to help manage your condition. This may include increasing your intake of foods rich in omega-3 fatty acids, staying hydrated, exercising regularly, and maintaining a healthy weight. Your doctor may also advise medications to reduce inflammation, prevent blood clots, or manage pain if necessary.
  • If your condition does not improve or persists, consult your doctor and report your condition. Your doctor will assess your progress, adjust your treatment plan if necessary, and provide appropriate advice to ensure the best possible outcome.

Directions for Use

  • Your doctor will determine the dosage and frequency depending on your condition.
  • Gercillin 500 Injection will be administered by a healthcare professional.
  • Do not self-administer.

How Gercillin 500 Injection Works

Gercillin 500 Injection belongs to a group of medicines known as penicillin-class antibiotics. It works by targeting and weakening the protective outer wall that bacteria need to survive. Without this strong cell wall, the bacteria cannot hold themselves together and will burst, which ultimately kills them. By stopping the bacteria from multiplying and spreading, your body’s natural immune system can easily clear the remaining infection.
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Alcohol

Unsafe

Avoid consumption of alcohol while on treatment with Gercillin 500 Injection.

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Pregnancy

Caution

Gercillin 500 Injection should not be used when pregnancy unless clearly necessary. So, inform your doctor if you are pregnant or planning a pregnancy before receiving this medicine.

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Breast Feeding

Unsafe

Breastfeeding should be stopped while receiving Gercillin 500 Injection as it can cause side effects to newborns. Hence, inform your doctor if you are breastfeeding before receiving this medicine.

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Driving

Safe

Gercillin 500 Injection does not affect your ability to drive.

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Liver

Safe if prescribed

Gercillin 500 Injection can be safely used in case of liver disease. However, consult your doctor in case of any concerns.

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Kidney

Caution

Gercillin 500 Injection should be used under caution in patients with kidney disease. Inform your doctor if you have kidney problems. Your doctor will prescribe only if the benefits outweigh the risks. Your doctor may adjust the dose based on your health condition.

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Children

Safe if prescribed

Gercillin 500 Injection can be given safely to children, the dose will be decided by your doctor based on the age and condition of your child.

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Heart

Consult your doctor

Gercillin 500 Injection is generally safe for heart patients as it doesn’t directly affect the cardiovascular system. However, always consult your doctor to ensure it won’t interact with other medications or underlying conditions.

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Geriatrics

Caution

Geriatric patients can receive Gercillin 500 Injection safely, but kidney function should be monitored closely as aging may reduce renal clearance. Dose adjustments might be necessary to avoid toxicity and ensure effectiveness.

What if I have taken an overdose of Gercillin 500 Injection

In case of an overdose, seek immediate medical attention or contact a poison control center. Symptoms of an overdose may include muscle spasms, seizures, or extreme confusion.

Diet & Lifestyle Advise

  • Support your gut health: Antibiotics can disrupt the healthy bacteria in your stomach. Eat yogurt or consider taking a probiotic supplement a few hours after your injection to help maintain gut balance.
  • Stay well-hydrated: Drink plenty of fluids like water, clear broths, or herbal teas to help your kidneys process and flush Gercillin 500 Injection efficiently.
  • Prioritize rest: Your body needs energy to fight off a severe infection. Limit physical exertion and ensure you get adequate sleep each night.
  • Complete the full course: Even if you start feeling better, ensure you complete the entire course of treatment exactly as prescribed to prevent the infection from returning.
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How Soon It Starts Working

The time required for Gercillin 500 Injection to start to work: Gercillin 500 Injection shows its action within 3 to 5 days of administration. The time for which the effects of Gercillin 500 Injection last: The duration of Gercillin 500 Injection’s effect is clinically not established.

What if you forget to take Gercillin 500 Injection

If you miss a dose, contact your doctor or nurse right away for instructions on when to receive your next dose. Do not receive a double dose to make up for a missed one.

Storage

• Store dry powder vials of Gercillin 500 Injection at room temperature, between 20°C and 25°C (68°F to 77°F), away from direct light and moisture.

Drug Warnings

  • Inspect the solution before use: Always check the mixed liquid before administration. It should be clear and colorless to pale yellow. Do not use it if it appears cloudy or contains visible particles.
  • Rotate injection sites: If repeated injections are required, use a different injection site each time to help reduce soreness and prevent tissue damage.
  • Practice safe needle disposal: Dispose of used needles and syringes immediately in an approved sharps container. Never place needles in regular household waste.
  • Monitor for allergic reactions: Watch closely for signs of an allergic reaction, especially during the first few doses. Seek emergency medical attention if you develop hives, difficulty breathing, or swelling of the face or throat.
  • Attend regular monitoring appointments: Your doctor may recommend periodic blood tests or kidney function tests during prolonged treatment.
  • Seek immediate medical attention if: You develop difficulty breathing, wheezing, swelling of the face, lips, tongue, or throat, severe watery or bloody diarrhea, seizures, severe confusion, loss of consciousness, unusual bruising or bleeding, or a rapidly spreading skin rash.
  • Use with caution in certain patients: Gercillin 500 Injection should not be used in people with a known allergy to Gercillin 500 Injection, penicillin, or other beta-lactam antibiotics, or in those who have previously experienced a severe allergic reaction (anaphylaxis) to penicillin-class medicines. People with infectious mononucleosis (mono) may develop a widespread skin rash with Gercillin 500 Injection. Patients with severe kidney impairment may require dose adjustments and close monitoring. Individuals with a history of severe reactions to previous Gercillin 500 Injection treatment should discuss alternative antibiotics with their healthcare provider.

Drug-Drug Interactions

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  • Gout medicines (e.g., allopurinol, probenecid): Taking these medicines alongside Gercillin 500 Injection may increase antibiotic levels in the body and raise the risk of side effects, including skin rashes.
  • Anti-cancer medicines (e.g., Methotrexate): Gercillin 500 Injection may reduce the removal of methotrexate from the body, increasing the risk of methotrexate toxicity.
  • Oral contraceptives (birth control pills): Gercillin 500 Injection may temporarily reduce the effectiveness of oral contraceptives. Consider using an additional non-hormonal method of contraception during treatment and discuss this with your doctor.
AmpicillinBCG vaccine
Critical
AmpicillinCholera, live attenuated
Severe

Drug-Drug Interactions

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AmpicillinBCG vaccine
Critical
How does the drug interact with Gercillin 500 Injection:
When BCG vaccine is used with Gercillin 500 Injection, its effectiveness may be reduced.

How to manage the interaction:
Taking Gercillin 500 Injection with BCG vaccine can lead to an interaction, please consult a doctor before taking it. Do not discontinue the medication without consulting a doctor.
AmpicillinCholera, live attenuated
Severe
How does the drug interact with Gercillin 500 Injection:
Co-administration of Gercillin 500 Injection with Cholera, live attenuated together may reduce the activity of the vaccine.

How to manage the interaction:
If you are currently being treated with Gercillin 500 Injection or have been treated within the last 14 days, talk to your doctor before receiving cholera vaccine, live. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Gercillin 500 Injection:
Co-administration of Methotrexate with Gercillin 500 Injection can increase the levels and side effects of Methotrexate.

How to manage the interaction:
Although there is a possible interaction between methotrexate and Gercillin 500 Injection, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as tiredness, dizziness, fainting, unusual bleeding or bruising, chills, fever, sore throat, body pains. Consult a doctor immediately. Do not stop using medications without a doctor's advice.

Drug-Food Interactions

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  • No clinically significant food interactions are known with Gercillin 500 Injection when used as directed.     
     
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTIBIOTICS]

FAQs

Gercillin 500 Injection is used to treat bacterial infections.
Gercillin 500 Injection contains ampicillin, an antibiotic that works by interfering with the formation of the bacterial cell wall (a protective covering) that is necessary for their survival. Thereby damaging the bacterial cell wall it kills bacteria.
Yes, Gercillin 500 Injection can be used to treat lung infections caused by bacteria. Gercillin 500 Injection is an antibiotic that kills bacteria and prevents the spread of infection.
No, this is an antibiotic medication. You need to complete the full course even if you start to feel better to prevent the return of infection and resistance to Gercillin 500 Injection.
Use of Gercillin 500 Injection may lower the efficiency of birth control pills. Ask your doctor about using other contraception devices like the diaphragm, condom, spermicide, copper T, etc., with Gercillin 500 Injection.
As Gercillin 500 Injection is injectable, it can start working soon after administration. However, Gercillin 500 Injection may take a few days to kill the bacteria and prevent the further spread of infection.
Do not use anti-diarrhoeal medication until the doctor has prescribed you. You can drink plenty of fluids (electrolytes) to avoid dehydration. Besides this, you can also take prebiotics or probiotics to manage diarrhoea, as it may help increase the number of good bacteria in the intestine, which aids in digestion.
Yes, in some cases, you can inject Gercillin 500 Injection at home after receiving proper training from a healthcare professional. You must carefully follow their instructions on preparation, sterile technique, and injection site care. Talk to your doctor if you have any questions.
Do not inject Gercillin 500 Injection if it looks cloudy, discolored, or contains visible particles. This could mean Gercillin 500 Injection is contaminated or has degraded. Contact your pharmacist or healthcare provider immediately for a replacement.
No, Gercillin 500 Injection is an antibiotic and only treats bacterial infections. It will not work against viral infections like colds, the flu, or COVID-19. Using antibiotics when they are not needed can lead to antibiotic resistance. Talk to your doctor for advice.
It is highly recommended to avoid alcohol while recovering from a serious bacterial infection. Alcohol can weaken your immune system, cause dehydration, and make it harder for your body to heal while receiving Gercillin 500 Injection. Talk to your doctor for personalized advice.
The most common side effects are mild and include pain, redness, or swelling where Gercillin 500 Injection was injected, as well as mild diarrhea or nausea. If these symptoms persist or worsen, talk to your doctor or pharmacist.
Gercillin 500 Injection is generally considered safe during pregnancy when prescribed by a doctor, but it should only be used if clearly needed. Always inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding before starting this treatment. Talk to your doctor for more information.
Yes. Gercillin 500 Injection is commonly prescribed in hospitals for newborns, infants, and children with serious bacterial infections. The dose and treatment duration vary depending on the child's age, weight, and medical condition, so it should only be administered under medical supervision.

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Country of origin

INDIA

Manufacturer/Marketer address

Zydus Tower, Satellite Cross Roads,Ahmedabad €“ 380015 Gujarat, India.
Other Info - GER0154
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