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compositionComposition:GLYCOPYRROLATE-2MG
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Prescription Medicine
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Gcolate 2mg Tablet is used to treat peptic ulcers in adults and children above 12 years. It is also used to treat severe drooling caused by certain neurologic disorders (cerebral palsy) in children 3 to 16 years of age. It contains Glycopyrrolate, which decreases stomach acid and saliva production. In some cases, it may cause dry mouth, vomiting, flushing, headache, and nasal congestion. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

GLYCOPYRROLATE-2MG

Manufacturer/Marketer :

Icon Life Sciences

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Gcolate 2mg Tablet

Gcolate 2mg Tablet is an oral prescription medication used to treat peptic ulcers by reducing stomach acid production. It is also commonly prescribed to help manage excessive drooling in patients with certain neurological conditions. This medicine helps dry up bodily secretions to relieve discomfort and protect delicate tissues.

To get the most benefit, you must take Gcolate 2mg Tablet consistently at the exact times prescribed by your doctor. It is typically taken two to three times a day, always on an empty stomach at least one hour before or two hours after eating. Making dietary adjustments, such as avoiding spicy foods and caffeine, can also help support your digestive health while using this medicine.

While taking this medication, you may experience mild side effects like a dry mouth, slightly blurred vision, or mild constipation. These are common reactions as your body adjusts, but you must consult your doctor immediately if you experience severe symptoms like difficulty urinating, a very fast heartbeat, or extreme dizziness.

Before starting Gcolate 2mg Tablet, you should talk to your doctor about your complete medical history, especially if you have high blood pressure, heart disease, or thyroid problems. Do not take this if you have narrow-angle glaucoma, severe bowel blockages, myasthenia gravis, or urinary retention.

This medicine can interact with alcohol, which may increase drowsiness, and with certain other medications that also cause dryness or sleepiness. It is important to discuss these risks with your healthcare provider, particularly if you are pregnant, breastfeeding, or an older adult, as some individuals may require a lower or gradually increasing dose.

Uses of Gcolate 2mg Tablet

Gcolate 2mg Tablet is used to reduce the activity of certain glands and secretions in the body. It may be prescribed for conditions involving excess stomach acid, saliva production, or sweating, including:

  • Peptic ulcers: Gcolate 2mg Tablet helps reduce stomach acid levels to assist in healing painful sores in the stomach lining.
  • Excessive drooling: Gcolate 2mg Tablet helps decrease saliva production in individuals with neurological conditions that cause swallowing difficulties.
  • Excessive sweating: Gcolate 2mg Tablet helps control severe, generalised sweating by blocking the sweat glands' chemical triggers.
     

Key Benefits

By reducing excessive secretions in different parts of the body, Gcolate 2mg Tablet provides several important benefits, including:

  • Targeted acid reduction: By lowering stomach acid, this medicine provides relief from burning pain, allowing your digestive tract to heal comfortably.
  • Effective drooling control: It significantly reduces excess saliva, which prevents skin irritation around the mouth and improves daily social comfort.
  • Reduced excessive sweating: It helps manage severe sweating, making daily physical tasks easier and reducing skin dampness and discomfort.
     

Directions for Use

  • Gcolate 2mg Tablet can be taken on an empty stomach, at least 1 hour before and 2 hours after food, as advised by the doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow Gcolate 2mg Tablet as a whole with a glass of water.
  • Do not chew, crush, or break it.

How Gcolate 2mg Tablet Works

Gcolate 2mg Tablet contains glycopyrrolate, an anticholinergic medicine that helps reduce the production of certain body secretions and relaxes smooth muscles in the digestive system. Gcolate 2mg Tablet works by blocking the action of acetylcholine, a natural chemical messenger in the body. Acetylcholine normally signals the glands to produce secretions such as saliva, sweat, and stomach acid. By blocking these signals, Gcolate 2mg Tablet helps reduce the production of these fluids. It also relaxes the smooth muscles of the digestive tract, which can help relieve symptoms associated with certain gastrointestinal conditions. Together, these actions help reduce excessive saliva production, decrease stomach acid secretion, and improve symptoms related to digestive system disorders.
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Alcohol

Caution

It is not known if alcohol interacts with Gcolate 2mg Tablet. Please consult your doctor.

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Pregnancy

Caution

Consult your doctor before taking Gcolate 2mg Tablet if you are pregnant; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor before taking Gcolate 2mg Tablet if you are breastfeeding; your doctor will decide whether Gcolate 2mg Tablet can be taken by breastfeeding mothers or not.

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Driving

Caution

Gcolate 2mg Tablet may cause sleepiness and blurred vision. Do not drive or operate machinery unless you are alert.

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Liver

Caution

If you have liver problems, please inform your doctor before taking this medicine.

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Kidney

Caution

If you have kidney problems, please inform your doctor before taking this medicine.

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Children

Safe if prescribed

It should be given only if prescribed by the doctor, and the dose and duration must be followed exactly as directed.

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Heart

Caution

Exercise caution while taking Gcolate 2mg Tablet if you any cardiac problems.

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Geriatrics

Caution

Gcolate 2mg Tablet should be used with caution in elderly patients due to the risk of other adverse effects.

What if I have taken an overdose of Gcolate 2mg Tablet

If you suspect an overdose, seek immediate medical attention or contact a poison control centre. Symptoms of an overdose may include severe dry mouth, extreme thirst, blurred vision, fast heart rate, or hot, dry skin.

Diet & Lifestyle Advise

  • Stay hydrated: Drink plenty of water throughout the day to help manage dry mouth, but take small sips rather than gulping.
  • Prevent overheating: Since this medicine decreases sweating, avoid hot baths, saunas, and intense exercise in hot weather to prevent heat stroke.
  • Eat fibre-rich foods: To prevent constipation, gradually increase your intake of high-fibre foods like vegetables, fruits, and whole grains, if permitted by your doctor.
  • Care for your mouth: Use sugarless candy, gum, or ice chips to relieve dry mouth, and maintain good oral hygiene to prevent cavities.
     
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How Soon It Starts Working

  • The time required for Gcolate 2mg Tablet to start to work: The time required for Gcolate 2mg Tablet to start to work is 30 to 60 minutes after administration.
  • The time for which the effects of Gcolate 2mg Tablet last: The effect of Gcolate 2mg Tablet lasts for 6 to 8 hours.

What if you forget to take Gcolate 2mg Tablet

Take the missed dose as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and resume your regular schedule. Do not take a double dose to make up for a missed one.

Storage

Store Gcolate 2mg Tablet at controlled room temperature, ideally between 20°C and 25°C (68°F to 77°F). • Keep the bottle tightly closed to protect the tablets from moisture and direct light.

Drug Warnings

  • Use Caution When Driving or Operating Machinery: Avoid driving or operating machinery until you know how this medicine affects your vision and alertness.
  • Avoid Excessive Heat Exposure: Limit your time in direct hot sun, as you may sweat less and be more prone to heat exhaustion.
  • Monitor Your Heart Rate: Check your pulse regularly and let your doctor know if you notice an unusually fast or irregular heartbeat.
  • Maintain Good Dental Care: Inform your dentist that you are taking this medicine, as chronic dry mouth can increase the risk of tooth decay and gum disease.
     

Drug-Drug Interactions

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Gcolate 2mg Tablet can interact with medicines that have anticholinergic effects or medicines that depend on normal stomach function for absorption, including:

  • Anticholinergic Medicines: Combining Gcolate 2mg Tablet with other anticholinergic drugs may increase side effects such as severe dry mouth, constipation, blurred vision, and difficulty urinating.
  • Certain Antidepressants: Some antidepressants can enhance the anticholinergic effects of Gcolate 2mg Tablet, increasing the risk of unwanted side effects.
  • Cold and Allergy Medicines: Certain over-the-counter cold medicines may contain ingredients that increase anticholinergic effects when taken together.
  • Other Oral Medications: Gcolate 2mg Tablet may reduce the absorption of medicines that require rapid dissolution in the stomach, potentially affecting their effectiveness.
     
GlycopyrrolatePotassium citrate
Critical

Drug-Drug Interactions

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GlycopyrrolatePotassium citrate
Critical
How does the drug interact with Gcolate 2mg Tablet:
Co-administration of Gcolate 2mg Tablet with Potassium citrate can increase the risk or severity of ulcers, bleeding, and other gastrointestinal injury.

How to manage the interaction:
Taking Gcolate 2mg Tablet with Potassium citrate together is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience severe abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, and/or black, tarry stools, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Gcolate 2mg Tablet:
Taking Gcolate 2mg Tablet with Potassium chloride can increase the risk or severity of ulcers, bleeding, and other gastrointestinal injury.

How to manage the interaction:
Taking Gcolate 2mg Tablet with Potassium chloride together is not recommended as it can possibly result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, and/or black, tarry stools, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Gcolate 2mg Tablet:
Coadministration of Gcolate 2mg Tablet with Zonisamide can increase the risk or severity of Zonisamide side effects like increased body temperature and decreased sweating especially in warm weather.

How to manage the interaction:
Taking Gcolate 2mg Tablet with Zonisamide together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience dizziness, drowsiness, fatigue, increased heart rate, fever, or excessive sweating, contact a doctor immediately. Make sure to hydrate yourself during warm weather or after exercise. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Gcolate 2mg Tablet:
Coadministration of Gcolate 2mg Tablet with Topiramate can increase the risk or severity of side effects like increased body temperature and decreased sweating.

How to manage the interaction:
Taking Gcolate 2mg Tablet with Topiramate together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience drowsiness, dizziness, lightheadedness, fever, chills, or decreased sweating, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip

Food can interfere with the absorption of Gcolate 2mg Tablet and may reduce how well the medicine works, including:

  • Food: Taking Gcolate 2mg Tablet with food can significantly reduce its absorption and effectiveness. It should be taken on an empty stomach as directed by your doctor.
     
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTICHOLINERGICS]

FAQs

Gcolate 2mg Tablet is used for the treatment of Peptic ulcers, Drooling (excessive salivation).
Dry mouth could be a side effect of Gcolate 2mg Tablet. Limiting caffeine intake, avoiding smoking, and drinking water regularly, chewing sugar-free gum/candy might stimulate saliva, thereby preventing drying of the mouth.
Do not stop taking Gcolate 2mg Tablet on your own. You are advised to take Gcolate 2mg Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. Do not be hesitant to speak with your doctor if you experience any difficulty while taking Gcolate 2mg Tablet.
Gcolate 2mg Tablet may cause sweating less, especially in children, leading to overheating and heat stroke. Avoid doing things that may cause you to overheat, such as exercising. Consult your doctor if you notice hot, red skin, fast, weak pulse, fast, shallow breathing, fever, or decreased alertness.
Gcolate 2mg Tablet decreases stomach acid and saliva production by blocking the activity of a certain natural substance in the body.
No, you should take Gcolate 2mg Tablet on an empty stomach, usually at least one hour before or two hours after meals, to ensure the medicine works effectively. Talk to your doctor or pharmacist if you have questions about your dosing schedule.
Some people may experience drowsiness, dizziness, or blurred vision while taking Gcolate 2mg Tablet. Avoid driving or performing tasks that require clear vision and alertness until you know how the medicine affects you. Talk to your doctor if these symptoms persist.
Gcolate 2mg Tablet works by blocking the chemical signals that stimulate your sweat glands, which can help reduce excessive sweating. Talk to your doctor or pharmacist to see if this is appropriate for your condition.
Dry mouth is a common effect of Gcolate 2mg Tablet. You can manage it by chewing sugar-free gum, sucking on ice chips, or drinking water frequently. Talk to your doctor or pharmacist if the dryness becomes severe or painful.
It is best to avoid alcohol while taking Gcolate 2mg Tablet. Alcohol can worsen side effects like drowsiness, dizziness, and blurred vision. Talk to your doctor for personalised advice.
The safety of Gcolate 2mg Tablet during pregnancy is not fully established. If you are pregnant, planning to become pregnant, or breastfeeding, talk to your doctor or pharmacist before starting this medicine to weigh the risks and benefits.
For oral tablets, Gcolate 2mg Tablet typically begins to work within one hour of taking it, and its effects can last for several hours. Talk to your doctor or pharmacist to understand what to expect based on your specific treatment plan.

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Country of origin

India
Other Info - GC66369
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