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compositionComposition:CASPOFUNGIN-50MG
prescriptionPrescription Medicine

Gcaspo-50 Combipack Injection 1's is used to treat fungal infections. It contains Caspofungin, which inhibits the formation of a fungal cell wall component required for the fungus to continue living and growing. When fungal cells are exposed to Caspofungin, their cell walls become partial or faulty, making them fragile and unable to grow. As a result, fungal cells get killed, or their growth is minimized.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

CASPOFUNGIN-50MG

Manufacturer/Marketer :

Glee Biotech Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Gcaspo-50 Combipack Injection 1's

Gcaspo-50 Combipack Injection 1's belongs to the class of medicines known as 'antifungals' used to treat various fungal infections. A fungal infection is caused when a fungus invades and affects any body part.

Gcaspo-50 Combipack Injection 1's contains Caspofungin, which inhibits the formation of a fungal cell wall component required for the fungus to continue living and growing. When fungal cells are exposed to Caspofungin, their cell walls become partial or faulty, making them fragile and unable to grow. As a result, fungal cells get killed, or their growth is minimized.

A qualified healthcare professional will administer Gcaspo-50 Combipack Injection 1's. In some cases, you may experience certain common side effects, such as injection site reactions, headaches, dizziness, nausea, vomiting, diarrhoea, stomach pain, tremors, sweating, high blood pressure, difficulty sleeping and swelling of the hands, ankles, or feet. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Before taking Gcaspo-50 Combipack Injection 1's, inform your doctor about your medical condition, sensitivities, and medications. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Do not use any other medicines with Gcaspo-50 Combipack Injection 1's without a doctor's recommendation. Gcaspo-50 Combipack Injection 1's may cause dizziness; therefore, avoid driving vehicles or operating machinery until you return to normal. Avoid the consumption of alcohol while on Caspofungin therapy.

Uses of Gcaspo-50 Combipack Injection 1's

Gcaspo-50 Combipack Injection 1's is used to treat serious fungal infections. The detailed uses of Gcaspo-50 Combipack Injection 1's are as follows:

  • Treats invasive candidiasis: Gcaspo-50 Combipack Injection 1's is used for yeast infections in the blood, stomach, lungs, and oesophagus.
  • Manages certain resistant fungal infections: Gcaspo-50 Combipack Injection 1's is given when other antifungal treatments have failed or are not suitable.
  • Used in immunocompromised patients: Gcaspo-50 Combipack Injection 1's helps treat serious fungal infections in people with weakened immune systems.

Key Benefits

Gcaspo-50 Combipack Injection 1's is an antifungal agent, a medicine used to treat several fungal infections. It can be used to treat fungal infections that other drugs have failed to treat. It is also used to treat serious fungal infections in persons who have a reduced immune system. Gcaspo-50 Combipack Injection 1's works by killing or preventing fungi or yeast by inhibiting an enzyme in fungi responsible for its membrane formation. As a result, fungal cells get killed, or their growth is minimized.

Side effects of Gcaspo-50 Combipack Injection
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
Managing Medication-Triggered Flushing (Reddening of the skin): A Step-by-Step Guide:
  • Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
  • Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
  • Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
  • Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
  • Eat foods rich in vitamin C, beta-carotene, and antioxidants, such as citrus fruits, orange vegetables, and berries.
  • Include healthy fats like fatty fish, avocados, and nuts in your diet.
  • Drink plenty of water and limit sun exposure to maintain skin hydration and protect against damage.
  • Practice stress management and relaxation techniques like deep breathing exercises, progressive muscle relaxation, and meditation.
  • Limit or avoid processed foods, sugary drinks, and excessive alcohol to prevent premature aging.
  • Consult a dermatologist if you experience significant changes in skin colour.
  • Chest pain may last for a while and needs immediate medical attention as it is a significant health issue to be attended to.
  • Take rest and refrain from doing physical activity for a while, and restart after a few days.
  • Try applying an ice pack to the strained area for at least 20 minutes thrice a day. Ice pack thus helps reduce inflammation.
  • Sit upright and maintain proper posture if there is persistent chest pain. • Use extra pillows to elevate your position and prop your chest up while sleeping.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safety.
  • Gcaspo-50 Combipack Injection 1's will be administered in the hospital setting by a trained healthcare professional.
  • Do not self-administer.

How Gcaspo-50 Combipack Injection 1's Works

Gcaspo-50 Combipack Injection 1's contains Caspofungin, which inhibits the formation of a fungal cell wall component required for the fungus to continue living and growing. When fungal cells are exposed to Caspofungin, their cell walls become partial or faulty, making them fragile and unable to grow. As a result, fungal cells get killed, or their growth is minimized.
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Alcohol

Caution

Avoiding alcohol is recommended to rule out any possibility of side effects.

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Pregnancy

Caution

Gcaspo-50 Combipack Injection 1's is generally not recommended in pregnancy. Your doctor may prescribe this medicine if the benefit to the mother outweighs the potential risk to the fetus.

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Breast Feeding

Caution

If you are breastfeeding, please inform your doctor. It is not known if Gcaspo-50 Combipack Injection 1's passes into breastmilk. Your doctor may advise you to stop breastfeeding before starting the treatment with Gcaspo-50 Combipack Injection 1's.

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Driving

Caution

Gcaspo-50 Combipack Injection 1's may cause dizziness; therefore, avoid driving vehicles or operating machinery until you return to normal.

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Liver

Caution

Inform your doctor before receiving the Gcaspo-50 Combipack Injection 1's if you have had a liver impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Inform your doctor before receiving the Gcaspo-50 Combipack Injection 1's if you have had a kidney impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Safe if prescribed

Please consult your doctor. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Heart

Caution

Inform your doctor before receiving the Gcaspo-50 Combipack Injection 1's if you have a heart disorder. Your doctor will prescribe only if the benefits outweigh the risks.

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Geriatrics

Safe if prescribed

Gcaspo-50 Combipack Injection 1's is generally safe for elderly patients. However, please consult your doctor if you have any concerns.

What if I have taken an overdose of Gcaspo-50 Combipack Injection 1's

Gcaspo-50 Combipack Injection 1's is administered in a hospital setting under the supervision of your doctor or medical personnel. Thus, an overdose is quite improbable. While in the hospital, you will be constantly monitored to ensure that any unpleasant side effects are handled.

Diet & Lifestyle Advise

  • It is advisable to follow a candida diet during fungal infections. This diet excludes sugar, gluten, certain dairy products, and alcohol. Switch to low-sugar fruits, non-starchy vegetables and gluten-free foods. A very high sugar or high-carbohydrate diet may increase the count of Candida in some people.
  • Create a well-balanced and healthy diet that includes vegetables, fruits, whole grains, legumes, omega-3-rich foods, and lean protein sources.
  • Limit or avoid alcohol consumption.
  • Quitting smoking is the best strategy to lower the risk of any disease.
  • Avoid sharing towels, combs, bedsheets, shoes or socks with others.
  • Wash your bedsheets and towels regularly.

Have a query?

How Soon It Starts Working

The time required for Gcaspo-50 Combipack Injection 1's to start to work: The effect of Gcaspo-50 Combipack Injection 1's starts within a few hours of administration. The time for which the effects of Gcaspo-50 Combipack Injection 1's last: The duration of Gcaspo-50 Combipack Injection 1's effect is unknown.

What if you forget to take Gcaspo-50 Combipack Injection 1's

As this medicine is administered in a hospital by your healthcare professional, the chances of missing a dose are less. However, if you have any concerns, contact your doctor.

Storage

• Store in a cool and dry place away from sunlight. • Keep Gcaspo-50 Combipack Injection 1's out of reach and sight of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

It is recommended not to use Gcaspo-50 Combipack Injection 1's if you are allergic to any component present, so inform your doctor about your sensitivities with medicines and foods. Also, let your doctor know about your medical condition and the medications you are currently using. Do not use any other drugs with Gcaspo-50 Combipack Injection 1's without a doctor’s recommendation. Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Drug-Drug Interactions

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Drug-Drug Interactions: Gcaspo-50 Combipack Injection 1's is known to interact with other antifungals (e.g. Ketoconazole), anticonvulsant medications (e.g. Carbamazepine, Phenytoin) and HIV medications (Efavirenz, Nelfinavir).

Drug-Food Interactions: No major interactions were found or established.

Drug-Disease Interactions: No major interactions were found or established.

Drug-Drug Interactions

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How does the drug interact with Gcaspo-50 Combipack Injection:
Taking Rifampicin in combination with Gcaspo-50 Combipack Injection may make Gcaspo-50 Combipack Injection less effective.

How to manage the interaction:
There may be a possibility of interaction between Gcaspo-50 Combipack Injection and Rifampicin, but it can be taken if prescribed by a doctor. Contact your doctor if your symptoms do not improve. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Gcaspo-50 Combipack Injection:
Coadministration of ketoconazole with Gcaspo-50 Combipack Injection may raise the risk of liver damage.

How to manage the interaction:
Although taking Ketoconazole and Gcaspo-50 Combipack Injection together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you have any of the following symptoms: fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, fatigue, lack of appetite, nausea, vomiting, abdominal pain, dark urine, light stools, and/or yellowing of the skin or eyes, consult a doctor. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Gcaspo-50 Combipack Injection:
Using nevirapine together with Gcaspo-50 Combipack Injection may cause Gcaspo-50 Combipack Injection to be less effective.

How to manage the interaction:
Although there is a possible interaction between Gcaspo-50 Combipack Injection and Nevirapine, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Gcaspo-50 Combipack Injection:
Leflunomide can cause liver problems, and combining it with other drugs, such as binimetinib, can raise the risk.

How to manage the interaction:
There may be a possibility of interaction between Leflunomide and Gcaspo-50 Combipack Injection, but it can be taken if prescribed by a doctor. If you have any of these symptoms, contact your doctor right away. These symptoms include liver problems, fever, rash, itching, loss of appetite, dark urine, stomach pain, unusual bleeding or bruising, feeling tired, and yellowing of the skin or eyes. Do not stop using any medications without a doctor's advice.
How does the drug interact with Gcaspo-50 Combipack Injection:
Co-administration of Dexamethasone with Gcaspo-50 Combipack Injection may cause Gcaspo-50 Combipack Injection to be less effective.

How to manage the interaction:
Although there is a possible interaction between Gcaspo-50 Combipack Injection and Dexamethasone, you can take these medicines together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Gcaspo-50 Combipack Injection:
Coadministration of Phenytoin and Gcaspo-50 Combipack Injection may decrease the blood levels of Gcaspo-50 Combipack Injection, which may make Gcaspo-50 Combipack Injection less effective.

How to manage the interaction:
Although taking Phenytoin and Gcaspo-50 Combipack Injection together can result in an interaction, it can be taken if your doctor has prescribed it. If your infection gets worse or if your symptoms don't go away, it is advised to consult a doctor. Without consulting a doctor, never stop taking any drugs.
CaspofunginFosphenytoin
Severe
How does the drug interact with Gcaspo-50 Combipack Injection:
Coadministration of Gcaspo-50 Combipack Injection and Fosphenytoin can reduce the levels of Gcaspo-50 Combipack Injection in the body. This can lead to low treatment outcomes.

How to manage the interaction:
Although there is a possible interaction between Gcaspo-50 Combipack Injection and Fosphenytoin, you can take these medicines together if prescribed by your doctor. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Gcaspo-50 Combipack Injection:
Taking Gcaspo-50 Combipack Injection and Efavirenz together reduces the levels and effectiveness of Gcaspo-50 Combipack Injection.

How to manage the interaction:
Although taking Gcaspo-50 Combipack Injection and Efavirenz together can evidently cause an interaction, it can be taken if your doctor has suggested it. Do not stop using any medications without a doctor's advice.
How does the drug interact with Gcaspo-50 Combipack Injection:
Taking carbamazepine and Gcaspo-50 Combipack Injection together may result in decreasing the effects of Gcaspo-50 Combipack Injection.

How to manage the interaction:
Although taking carbamazepine and Gcaspo-50 Combipack Injection together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIFUNGALS]

FAQs

Gcaspo-50 Combipack Injection 1's is used to treat Fungal infections.

Gcaspo-50 Combipack Injection 1's contains Caspofungin, which inhibits the formation of a fungal cell wall component required for the fungus to continue living and growing. When fungal cells are exposed to Caspofungin, their cell walls become partial or faulty, making them fragile and unable to grow.

Gcaspo-50 Combipack Injection 1's is not suitable for patients with known hypersensitivity to any components present in Gcaspo-50 Combipack Injection 1's.

Gcaspo-50 Combipack Injection 1's is unlikely to interfere with your contraception, including the combination pill or emergency contraception. For further information, seek medical advice from your healthcare professional.

Yes, fungal infection is a contagious skin condition that spreads from one person to another through direct skin-to-skin contact or by contact with contaminated soil or surfaces and infected animals. Therefore, avoiding close direct contact until the infection is clear and avoiding sharing things with the infected person is recommended, as it can also spread the infection.

No, you can continue to eat and drink normally while taking Gcaspo-50 Combipack Injection 1's unless instructed by the doctor.

No, Gcaspo-50 Combipack Injection 1's is not an antibiotic. It belongs to the class of medicines called antifungals.

Gcaspo-50 Combipack Injection 1's is administered as a slow intravenous injection, usually once a day, by a qualified healthcare professional. The injection is given over about one hour. The dosage and treatment duration will be determined by your doctor based on your specific condition. Do not self-administer.

Gcaspo-50 Combipack Injection 1's targets fungal infections. It works by inhibiting the growth of the fungi, helping to treat conditions like candidemia (bloodstream infection) and invasive aspergillosis (serious infection by aspergillus fungus, in the lungs).

Gcaspo-50 Combipack Injection 1's is effective when used as per the dosage and duration recommended by a doctor. Do not self-medicate.

Gcaspo-50 Combipack Injection 1's causes side effects such as injection site reactions, headache, dizziness, chills, nausea, vomiting, diarrhoea, stomach pain tremor, high blood pressure, swelling of hands, ankles, or feet and difficulty sleeping. Please, consult a doctor if these persist for longer durations.

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Country of origin

India

Manufacturer/Marketer address

315, 3rd Floor, SAS Towers, Medicity, Sector 38, Gurugram, Haryana 122018
Other Info - GCA0017
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