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GABASAFE PLUS TABLET is a combination medicine used in the treatment of neuropathic pain and nutritional deficiencies. This medicine works by altering the nerve signals that cause pain and thereby protects nerve fibres. It helps provide a protective effect on the nerve tissues and the brain. You may experience common side effects like nausea, vomiting, diarrhoea, and stomach upset.

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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Composition :

ALPHA LIPOIC ACID-100MG+MECOBALAMIN-750MCG+PREGABALIN-75MG

Manufacturer/Marketer :

Aristo Pharmaceuticals Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About GABASAFE PLUS TABLET

GABASAFE PLUS TABLET is a prescription medication primarily used to manage chronic nerve pain, also known as neuropathic pain. This discomfort often stems from conditions like diabetes, shingles, or spinal cord injuries that damage the nervous system. By targeting the source of nerve irritation, GABASAFE PLUS TABLET helps restore physical comfort and improve daily function.

For the best results, you should take GABASAFE PLUS TABLET consistently at the same times every day as directed by your doctor. This oral medication can be taken with or without food, making it easy to fit into your daily routine. Making simple lifestyle adjustments, such as eating a balanced diet rich in essential vitamins and engaging in low-impact daily exercise like walking, can significantly enhance your recovery and nerve health.

While taking GABASAFE PLUS TABLET, you might experience mild side effects such as temporary drowsiness, dizziness, or dry mouth. However, if you notice serious symptoms like swelling in your hands or feet, unexplained muscle pain, or sudden mood changes, you must contact your doctor immediately.

Before starting GABASAFE PLUS TABLET, it is crucial to discuss your medical history with your healthcare provider, especially if you have a history of kidney disease, heart problems, or mood disorders. Do not take this medication if you have had a severe allergic reaction to any of its ingredients in the past.

Avoid drinking alcohol while taking GABASAFE PLUS TABLET because it can worsen drowsiness and dizziness, increasing your risk of falls. Additionally, talk to your doctor or pharmacist if you are pregnant, breastfeeding, or planning a pregnancy, as well as if you are an elderly individual, to ensure this medication is safe for your specific needs.

Uses of GABASAFE PLUS TABLET

GABASAFE PLUS TABLET is used to manage chronic nerve pain, also known as neuropathic pain. The detailed uses of GABASAFE PLUS TABLET are as follows:

  • Diabetic Neuropathy: GABASAFE PLUS TABLET helps relieve the burning, stabbing, or tingling pain in the hands and feet caused by high blood sugar nerve damage.
  • Postherpetic Neuralgia: It eases the persistent, sharp nerve pain that remains after an episode of shingles.
  • Fibromyalgia: GABASAFE PLUS TABLET reduces widespread musculoskeletal pain, stiffness, and chronic fatigue associated with this condition.
  • Spinal Cord Injury Pain: It helps manage chronic, deep nerve pain resulting from trauma or injury to the spine.

Key Benefits

GABASAFE PLUS TABLET helps relieve chronic nerve pain by calming irritated nerves and supporting healthy nerve function. With regular use, it reduces discomfort, improves sleep quality, and enhances your overall quality of life.

  • Relieves Nerve Pain: By targeting the underlying causes of nerve irritation, this medicine helps reduce persistent nerve pain, allowing you to move more comfortably and carry out your daily activities with greater ease.
  • Improves Sleep Quality: By calming overactive nerves, this medicine helps reduce night-time nerve pain, promoting more restful and uninterrupted sleep.
  • Supports Daily Well-Being: Better pain control and improved sleep help increase daytime energy, support natural recovery, and improve overall physical function and quality of life.
Side effects of Gabasafe Plus Tablet
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.

Directions for Use

  • Take GABASAFE PLUS TABLET with or without food, or as advised by the doctor.
  • Follow your doctor’s recommendations on the dosage and timing of this medication to achieve optimal results.
  • Swallow GABASAFE PLUS TABLET as a whole with a glass of water.
  • Do not crush, chew, or break it.

How GABASAFE PLUS TABLET Works

GABASAFE PLUS TABLET combines three active components that work together in harmony to relieve nerve pain and support nerve repair. Each ingredient targets a different aspect of nerve health to provide comprehensive relief. The first active component, pregbalin, works directly on the central nervous system. It binds to specific sites on damaged nerves, reducing the release of excess chemical messengers that transmit pain signals to the brain. This effectively dampens the sensation of pain, bringing rapid relief to burning or shooting discomfort. The second component, mecobalamin, is an essential coenzyme form of Vitamin B12. It plays a critical role in producing myelin, the protective outer coating that surrounds and insulates your nerves. By promoting myelin regeneration, this ingredient helps repair damaged nerve fibres and restores normal nerve signal transmission. The third component, alpha lipoic acid, is a powerful, naturally occurring antioxidant. It neutralises harmful free radicals that cause oxidative damage to nerve cells. By improving blood flow to the nerves and protecting them from further cellular damage, this antioxidant supports the overall healing and survival of nerve tissues.
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Alcohol

Unsafe

Avoid consumption of alcohol while taking GABASAFE PLUS TABLET as it may increase dizziness and sleepiness.

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Pregnancy

Caution

Avoid taking GABASAFE PLUS TABLET if you are pregnant unless prescribed by a doctor. Please consult your doctor if you have any concerns regarding this, your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor before taking GABASAFE PLUS TABLET; your doctor will decide whether GABASAFE PLUS TABLET can be taken by breastfeeding mothers or not.

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Driving

Caution

GABASAFE PLUS TABLET causes drowsiness, sleepiness and tiredness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

GABASAFE PLUS TABLET should not be given to children as the safety and efficacy have not been established.

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Heart

Caution

GABASAFE PLUS TABLET should be taken with caution in patients with heart problems. Therefore, please talk to your doctor before using GABASAFE PLUS TABLET.

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Geriatrics

Caution

GABASAFE PLUS TABLET should be given at a lower dose for elderly patients to minimize risks, as advised by a healthcare professional.

What if I have taken an overdose of GABASAFE PLUS TABLET

If you accidentally take more than your prescribed amount of GABASAFE PLUS TABLET, seek immediate medical attention. Symptoms of an overdose may include extreme sleepiness, confusion, agitation, or a rapid heartbeat.

Diet & Lifestyle Advise

  • Manage blood sugar levels: If you have diabetic neuropathy, closely monitor your blood glucose, as stable blood sugars prevent further nerve damage.
  • Inspect your feet daily: Since nerve pain can sometimes mask injuries, check your feet daily for cuts, blisters, or redness to avoid unnoticed infections.
  • Incorporate B-complex foods: Eat foods rich in vitamins, such as lean meats, eggs, dairy, and fortified cereals, to support natural nerve healing.
  • Stay active with low-impact exercise: Engage in gentle physical activities like swimming or cycling, which boost blood circulation to your extremities and ease nerve discomfort.
  • Avoid alcohol and smoking: Both alcohol and tobacco smoke can directly damage nerves and worsen symptoms of neuropathy.
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How Soon It Starts Working

The time required for GABASAFE PLUS TABLET to start to work: GABASAFE PLUS TABLET ideally shows its action within few hours after administration. The time for which the effects of GABASAFE PLUS TABLET last: The duration of action for GABASAFE PLUS TABLET is clinically unknown.

What if you forget to take GABASAFE PLUS TABLET

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Storage

• Store GABASAFE PLUS TABLET at room temperature, ideally between 20°C and 25°C (68°F to 77°F).

Drug Warnings

  • Avoid driving or operating machinery: Do not drive, ride a bicycle, or use power tools until you know how GABASAFE PLUS TABLET affects you, as it frequently causes drowsiness or dizziness.
  • Watch for mood changes: Pay close attention to sudden changes in your mental health, and ensure your family members are aware of the risk of mood swings or depression.
  • Avoid sudden discontinuation: Do not stop taking this medicine abruptly, as doing so can trigger withdrawal symptoms like sleep trouble, headache, nausea, or anxiety. Talk to your doctor about gradually decreasing your dose.
  • Be cautious with hot baths: Neuropathy can reduce your ability to feel extreme temperatures. Always test bathwater with your elbow or a thermometer to prevent accidental burns.
  • Limit sedative medications: Consult your doctor before taking sleep aids, muscle relaxers, or strong pain relievers, as combining them with GABASAFE PLUS TABLET can cause severe sleepiness or breathing difficulties.

Drug-Drug Interactions

verifiedApollotooltip
  • Central nervous system depressants: Combining GABASAFE PLUS TABLET with anti-anxiety medications, sleeping pills, or narcotic pain medicines can cause severe drowsiness and slow your breathing.
  • Certain diabetes medicines: Taking this medication alongside some diabetes drugs (such as pioglitazone or rosiglitazone) may increase the risk of fluid retention and weight gain.
Mecobalamin + PregabalinBuprenorphine
Severe
Mecobalamin + PregabalinTapentadol
Severe

Drug-Drug Interactions

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Mecobalamin + PregabalinBuprenorphine
Severe
How does the drug interact with Gabasafe Plus Tablet:
Using Pregabalin together with Buprenorphine causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Buprenorphine and Pregabalin together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience dizziness, drowsiness, difficulty concentrating, and impairment in judgment, reaction speed, and motor coordination, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
Mecobalamin + PregabalinTapentadol
Severe
How does the drug interact with Gabasafe Plus Tablet:
Using Tapentadol together with Pregabalin may cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Taking Pregabalin with Tapentadol can result in an interaction, it can be taken if a doctor has advised it. Contact a doctor immediately if you experience signs such as drowsiness, lightheadedness, palpitations, confusion, severe weakness, or difficulty breathing. Do not discontinue any medications without consulting a doctor.
Mecobalamin + PregabalinTramadol
Severe
How does the drug interact with Gabasafe Plus Tablet:
When Tramadol is used with Pregabalin, it may lead to side effects such as respiratory difficulties, and unconsciousness.

How to manage the interaction:
Although taking tramadol and pregabalin together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
Mecobalamin + PregabalinButorphanol
Severe
How does the drug interact with Gabasafe Plus Tablet:
Using Pregabalin together with Butorphanol causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Butorphanol and pregabalin together can result in an interaction, it can be taken if a doctor has prescribed it. If you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
Mecobalamin + PregabalinDezocine
Severe
How does the drug interact with Gabasafe Plus Tablet:
Using Pregabalin together with Dezocine causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking Dezocine and Pregabalin together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
Mecobalamin + PregabalinAlfentanil
Severe
How does the drug interact with Gabasafe Plus Tablet:
Using Pregabalin together with Alfentanil causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking Pregabalin and Alfentanil together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience dizziness, drowsiness, difficulty concentrating, and impairment in judgment, reaction speed, and motor coordination, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
Mecobalamin + PregabalinNalbuphine
Severe
How does the drug interact with Gabasafe Plus Tablet:
Using Pregabalin together with Nalbuphine causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking Nalbuphine and Pregabalin together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
Mecobalamin + PregabalinRemifentanil
Severe
How does the drug interact with Gabasafe Plus Tablet:
Using Pregabalin together with Remifentanil causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking Remifentanil and Pregabalin together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
Mecobalamin + PregabalinSodium oxybate
Severe
How does the drug interact with Gabasafe Plus Tablet:
Using Sodium oxybate together with Pregabalin may increase the risk of side effects.

How to manage the interaction:
Although taking Pregabalin with Sodium oxybate together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience drowsiness, dizziness, lightheadedness, confusion, slow or shallow breathing, and impairment in thinking, judgment, and motor coordination, consult the doctor. Do not stop using any medications without talking to a doctor.
Mecobalamin + PregabalinMethadone
Severe
How does the drug interact with Gabasafe Plus Tablet:
Using Pregabalin together with Methadone causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking methadone and pregabalin together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • Alcohol: Avoid consuming alcohol while taking GABASAFE PLUS TABLET, as it significantly increases the sedative effects, leading to severe dizziness and loss of coordination.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[MISCELLANEOUS]

FAQs

No. Do not stop taking GABASAFE PLUS TABLET suddenly, even if your pain improves or you feel well. Stopping it abruptly may cause withdrawal symptoms such as nausea, headache, anxiety, difficulty sleeping, or sweating. Continue taking GABASAFE PLUS TABLET for as long as your doctor prescribes. If treatment needs to be stopped, your doctor will gradually reduce your dose to minimize withdrawal symptoms.
Yes. GABASAFE PLUS TABLET may cause weight gain, which may be related to an increased appetite, fluid retention, or swelling in the hands and feet. Eating a balanced diet and exercising regularly may help manage weight. If you notice rapid, significant, or unusual weight gain or swelling, contact your doctor.
Yes. GABASAFE PLUS TABLET may cause drowsiness, sleepiness, or dizziness, especially when you first start treatment or your dose is increased. Avoid driving, operating machinery, or performing tasks that require alertness until you know how the medicine affects you. If these effects are severe or persistent, talk to your doctor.
GABASAFE PLUS TABLET is generally not recommended during pregnancy unless your doctor decides the benefits clearly outweigh the risks. If you are pregnant, planning to become pregnant, or breastfeeding, talk to your doctor before starting or continuing this medication.
You should avoid alcohol, as it can worsen drowsiness and dizziness. Also, avoid taking other medications that cause sleepiness, such as sleeping pills or muscle relaxants, without checking with your healthcare provider first. Talk to your doctor or pharmacist about all the substances you use.
Yes, GABASAFE PLUS TABLET is frequently prescribed to people with diabetes to treat nerve pain. However, certain diabetes medications may interact with it, potentially increasing fluid retention or swelling. Always share a complete list of your current medications with your healthcare team. Talk to your doctor to ensure your combination is safe.
GABASAFE PLUS TABLET does not cure the underlying condition causing your nerve damage, but it helps manage the pain symptoms and supports the body's natural nerve repair mechanisms. For a comprehensive treatment plan that addresses the root cause of your condition, talk to your doctor.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Mercantile Chamber, 3rd Floor, 12, J.N. Heredia Marg, Ballard Estate, Mumbai – 400 001, India.
Other Info - GAB0042

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