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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Frusenex 100 Tablet belongs to the class of loop diuretics. It is used to treat Oedema (swelling) and hypertension (high blood pressure). This medicine contains frusemide, which works by reducing the excess fluid levels in the body and thus reducing swelling. Common side effects include frequent urination, feeling thirsty, dry mouth, headache, nausea or vomiting, headache, confusion, and dizziness.

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Composition :

FRUSEMIDE-100MG

Manufacturer/Marketer :

Geno Pharmaceuticals Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Frusenex 100 Tablet

Frusenex 100 Tablet  is used to treat high blood pressure, heart failure, and oedema (a fluid build-up in the body). Hypertension or high blood pressure is a chronic condition in which the force exerted by the blood against the artery wall is high. If the blood pressure is high, it is harder for the heart to pump. As a result, it leads to heart disease, irregular heartbeat, and other complications. Oedema may occur in cases of high blood pressure, where body fluids get trapped in the tissues of the hands, arms, feet, ankles, and legs, leading to swelling.

Frusenex 100 Tablet works by increasing the amount of urine passed out from the kidneys. It effectively reduces excess fluid levels in the body and treats oedema (swelling) associated with heart, liver, kidney, or lung disease. This reduces the workload on the heart and makes the heart more efficient at pumping blood throughout the body. Thus, it helps lower high blood pressure, reducing the chances of a heart attack or stroke.

You can take Frusenex 100 Tablet with food or without food. It should be swallowed whole with a glass of water. Do not chew, bite, or break it. Your doctor will advise you on how often you take medication based on your medical condition. Sometimes, you may experience dehydration, headache, nausea, or dizziness. Most of these side effects of Frusenex 100 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist, contact your doctor.

Try not to stop taking this medication on your own. Let your doctor know about this, as it may cause a rise in blood pressure and can increase the risk of heart disease and stroke. Inform your doctor if you have kidney, liver, or heart disease. If you are pregnant or breastfeeding, please tell your doctor so that the dosage of Frusenex 100 Tablet can be prescribed accordingly. Please tell your doctor if you have had an allergic reaction to Frusenex 100 Tablet or any other medicine in the past. Reducing the amount of table salt (sodium chloride) in your food often relieves the swelling of the body.

Uses of Frusenex 100 Tablet

Frusenex 100 Tablet is used in the treatment of high blood pressure, heart failure, and oedema (fluid build-up). The detailed uses of Frusenex 100 Tablet are as follows:<br/>• Treatment of High Blood Pressure (Hypertension): It helps lower blood pressure by reducing fluid in the body, easing the heart's workload.<br/>• Treatment of Heart Failure: It reduces fluid retention, improves heart function, and reduces symptoms like swelling and shortness of breath.<br/>• Treatment of Oedema (Fluid Build-Up): It helps remove excess fluid from the body, reducing swelling in areas like the legs, feet, and ankles.<br/>

Directions for Use

  • Frusenex 100 Tablet can be taken orally with or without food, or as directed by your physician.
  • It is best to avoid taking this medication within 4 hours of your bedtime to prevent having to get up to urinate.
  • Swallow the tablet whole with a full glass of water; do not crush, chew, or break it.

Medicinal Benefits

When you take Frusenex 100 Tablet , the blood vessels in your body will be relaxed, which will help lower the blood pressure. Also, it relaxes the blood vessels and helps improve blood flow. It helps lose excess fluids from the body by increasing urine production. This reduces the workload on the heart and makes the heart more efficient at pumping blood throughout the body. Thus, it helps lower high blood pressure, reducing the chances of a heart attack or stroke. In addition, this relieves oedema and enables you to carry out your daily activities more efficiently.

How Frusenex 100 Tablet Works

Frusenex 100 Tablet works by increasing the amount of urine passed out from the kidneys. It effectively reduces excess fluid levels in the body and treats oedema (swelling) associated with heart, liver, kidney, or lung disease. This reduces the workload on the heart and makes the heart more efficient at pumping blood throughout the body. Thus, it helps lower high blood pressure, reducing the chances of a heart attack or stroke.

Storage

• Store in a cool and dry place away from sunlight.
• Keep out of sight and reach of children.
• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Frusenex 100 Tablet
  • Consume controlled amounts of salt to raise sodium levels.
  • Eat fresh fruits like apples, berries, oranges, mangoes, and bananas.
  • Include fresh vegetables like broccoli, sweet potatoes, beets, okra, spinach, peppers, carrots, and edamame.
  • Choose frozen vegetables without added butter or sauce.
  • Drink electrolyte beverages like sports drinks or electrolyte solutions to replenish sodium and other electrolytes.
  • Avoid excessive salt intake, but allow for controlled increases as needed.
  • Monitor and manage underlying health conditions that may contribute to hyponatremia.
  • Let your doctor know if you experience symptoms such as fatigue, weakness, muscle cramps, or respiratory depression. Hyperchloremia may cause these.
  • Hyperchloremia is a condition in which the blood has an excessive level of chloride ions, which can disrupt the body's acid-base balance and lead to various complications.
  • Your doctor will thoroughly evaluate to determine if your medication is causing the hyperchloremia.
  • If your medication is found to be the cause, your doctor may adjust your medication regimen or switch you to alternative medicines.
  • To manage hyperchloremia, focus on consuming a balanced diet that is low in chloride-rich foods. Include potassium-rich foods like bananas, leafy greens, and sweet potatoes to help balance electrolyte levels.
  • Adopting a healthy lifestyle can help manage your condition. Aim for regular physical activity, stress-reducing techniques, and adequate sleep to help your body recover.
  • Regular monitoring and follow-ups with your doctor are crucial to managing your condition. Schedule check-ups as recommended by your doctor to monitor your symptoms and adjust your treatment plan as needed.
  • Talk to your doctor about oral potassium supplements.
  • Eat potassium rich foods such as bananas, avocados, oranges, dark leafy greens, beans and peas, fish, spinach, milk and tomatoes.
  • Drink plenty of water to eliminate uric acid.
  • Avoid purine-rich foods such as red meat, organ meats, certain seafood (sardines, anchovies) and too much alcohol.
  • Regularly do low impact exercises like swimming or walking.
  • To reduce pain and swelling, apply ice packs to the affected area.
  • Take rest and avoid activities that strain the affected joint.
  • Elevate the affected joint to encourage fluid drainage.
  • Aim for weight loss and maintain a healthy body weight to reduce the risk of gout.

What if I have taken an overdose of Frusenex 100 Tablet

Do not take more than the prescribed dose of Frusenex 100 Tablet as it may cause an overdose. The symptoms of overdose include heavy sweating, feeling very thirsty or hot, extreme weakness, fainting, or hot and dry skin. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Frusenex 100 Tablet should not be given to people allergic to Frusenex 100 Tablet , have low blood pressure (less than 90 mm of Hg), have had a heart attack, kidney disease, or liver disease, are pregnant women, or are planning to get pregnant or breastfeeding women. Besides this, it is contraindicated in low blood pressure (hypotension), cardiogenic shock (sudden stopping of blood flow to the heart), and aortic stenosis (heart valve problem). Frusenex 100 Tablet can pass into breast milk, but its effect on the baby is unknown. So, it is better to tell your doctor if you take Frusenex 100 Tablet and are breastfeeding.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Frusenex 100 Tablet:
Taking Ziprasidone with Frusenex 100 Tablet can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Ziprasidone with Frusenex 100 Tablet is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, weakness, tiredness, drowsiness, confusion, muscle pain, cramps, dizziness, nausea, or vomiting. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Frusenex 100 Tablet:
Concomitant administration of diclofenac and Frusenex 100 Tablet may decrease the therapeutic efficacy of Frusenex 100 Tablet and adversely affect renal function.

How to manage the interaction:
There may be a possible interaction between diclofenac and Frusenex 100 Tablet, but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience symptoms like nausea, dizziness, irregular heartbeats, altered blood pressure, tingling. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Frusenex 100 Tablet:
Co-administration of Frusenex 100 Tablet may interfere with blood glucose control and lower the effectiveness of Glimepiride.

How to manage the interaction:
Although there is a possible interaction, glimepiride can be taken with Frusenex 100 Tablet if prescribed by the doctor. Regular monitoring of blood glucose levels is advised. Do not discontinue the medications without consulting a doctor.
How does the drug interact with Frusenex 100 Tablet:
Taking Frusenex 100 Tablet with Tobramycin can increase the risk of hearing loss and kidney problems.

How to manage the interaction:
Although there is a possible interaction between Tobramycin and Frusenex 100 Tablet, you can take these medicines together if prescribed by your doctor. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Frusenex 100 Tablet:
Coadministration of Amikacin with Frusenex 100 Tablet can increase the risk of developing kidney disorder and other side effects.

How to manage the interaction:
Although taking amikacin and Frusenex 100 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience ringing in the ears, irregular urination, muscle cramps, vomiting, or weakness, consult the doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Frusenex 100 Tablet:
Coadministration of Streptomycin and Frusenex 100 Tablet may increase the risk or severity of hearing or kidney problems.

How to manage the interaction:
There may be a possibility of interaction between Streptomycin and Frusenex 100 Tablet, but it can be taken if prescribed by a doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, hearing difficulty, swelling, body aches, increased or decreased urination, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Frusenex 100 Tablet:
Combining Tizanidine and Frusenex 100 Tablet can lower your blood pressure.

How to manage the interaction:
Taking Tizanidine and Frusenex 100 Tablet together can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like headache, dizziness, lightheadedness, fainting, and changes in pulse or heart rate, contact your doctor immediately. Avoid driving or operating hazardous machinery until you know how the medications affect you, use caution when getting up from a sitting or lying position, and do not discontinue any medications without consulting your doctor.
FurosemideTirzepatide
Moderate
How does the drug interact with Frusenex 100 Tablet:
Frusenex 100 Tablet may decrease the effectiveness of tirzepatide thereby causing the increase in blood glucose levels.

How to manage the interaction:
Close blood glucose monitoring is recommended when on treatment with Frusenex 100 Tablet.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Keep your weight under control with a BMI of 19.5-24.9.
  • Regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week, can help lower your raised blood pressure by about 5 mm of Hg.
  • Opt for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.
  • Limit your daily sodium chloride (table salt) intake to 2300 mg per day, or less than 1500 mg, which is ideal for most adults.
  • If you are taking alcohol, then only one serving for women and two for men is advisable.
  • Quitting smoking is the best strategy to lower the risk of heart disease.
  • Avoid chronic stress, as it can raise your blood pressure. To cope with stress, try to enjoy and spend time with your loved ones and practice mindfulness techniques.
  • Try to include heart-healthy omega-3 fatty acid-containing food and drinks in your daily diet. You can also use low-fat cooking oils like olive oil, soybean oil, canola oil, and coconut oil to help lower your elevated blood pressure.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES
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Alcohol

Caution

You are recommended not to consume alcohol while using Frusenex 100 Tablet to avoid unpleasant side effects.

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Pregnancy

Caution

Frusenex 100 Tablet should not be used in pregnancy unless necessary. Your doctor will weigh the benefits and potential risks before prescribing Frusenex 100 Tablet to you. Please consult your doctor.

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Breast Feeding

Caution

Frusenex 100 Tablet should not be used in breastfeeding unless necessary. Your doctor will weigh the benefits and potential risks before prescribing Frusenex 100 Tablet . Please consult your doctor.

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Driving

Caution

Driving after taking Frusenex 100 Tablet is not recommended as it may occasionally cause drowsiness.

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Liver

Caution

Frusenex 100 Tablet to be taken with caution if you have a history of liver diseases/conditions. Your doctor may adjust the dose depending on your current liver condition.

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Kidney

Caution

Frusenex 100 Tablet to be taken with caution if you have a history of kidney diseases/conditions. Your doctor may adjust the dose depending on your condition.

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Children

Caution

Frusenex 100 Tablet can be used in children if prescribed by a doctor. The dose of this medicine will be decided by your doctor based on your child's age and body weight.

Have a query?

FAQs

Frusenex 100 Tablet is used to treat high blood pressure, heart failure, and oedema (a build-up of fluid in the body).

Frusenex 100 Tablet works by increasing the amount of urine from the kidneys. It effectively reduces excess fluid levels in the body and treats oedema (swelling) associated with heart, liver, kidney, or lung disease. This reduces the workload on the heart and makes the heart more efficient at pumping blood throughout the body. Thus, it helps lower high blood pressure, reducing the chances of a heart attack or stroke.

Oedema or Edema is a medical term for fluid retention. The affected area begins to swell as a result of oedema. If it does not go away, please see your doctor right away.

Your symptoms may improve before the problem is completely cured. However, it is suggested that you complete the entire course of treatment even if you feel better.

Yes, Frusenex 100 Tablet is contraindicated to any of the components of Frusenex 100 Tablet in people with known allergies. It should be avoided in people with severe kidney or liver impairment and with anuria (reduction or absence of urine).

No, you are advised to inform your doctor and monitor your blood pressure for at least two weeks before stopping the medicine. Depending on your current blood pressure readings, your doctor may lower your medication dosage and not recommend discontinuing it.

Frusenex 100 Tablet can be safely taken as long as your doctor prescribes it. Conditions such as high blood pressure are lifelong, and one should not abruptly discontinue them without discussing them with a doctor.

No, gout due to Frusenex 100 Tablet is very rare. However, it can increase uric acid levels.

There is no evidence that Frusenex 100 Tablet reduces fertility in men or women. However, if you are a woman trying to get pregnant, talk to your doctor first.

Frusenex 100 Tablet is used to treat high blood pressure, heart failure, and oedema (a fluid build-up in the body).

As your body loses water, you may experience slight weight loss while taking Frusenex 100 Tablet . However, Frusenex 100 Tablet is not used to treat weight loss.

Frusenex 100 Tablet may decrease blood pressure by reducing excess fluid in the body. This decreases the volume of blood circulating and lowers the pressure on blood vessel walls. It also helps to relax blood vessels, contributing to improved blood flow.

Frusenex 100 Tablet may cause an increase in uric acid levels in the blood by reducing its renal excretion. It inhibits the active transport of uric acid in the renal tubules, leading to decreased elimination of uric acid in urine. This may result in the build-up of uric acid in the bloodstream, potentially raising uric acid levels in the blood. Consult the doctor if you have gout/high uric acid levels.

Frusenex 100 Tablet may cause a decrease in potassium levels by increasing the excretion of potassium through urine. It inhibits sodium reabsorption in the kidneys, leading to enhanced potassium loss in the urine.

The side effects of Frusenex 100 Tablet include headache, dehydration, nausea, or dizziness. Consult the doctor if any of these side effects persist or worsen.

Frusenex 100 Tablet should be taken orally with or without food as recommended by the doctor. Swallow Frusenex 100 Tablet as a whole with water. Do not chew, crush or break it.

The best time to take Frusenex 100 Tablet can be determined by the doctor based on your medical condition. However, it is recommended to avoid taking Frusenex 100 Tablet within 4 hours of your bedtime to prevent the need to get up during the night to urinate.

Both furosemide and torasemide belong to the group of medications called loop diuretics used to treat high blood pressure and oedema caused by underlying liver, kidney, or lung diseases. However, both are different medications and your doctor will decide which medicine is suitable for you based on your condition.

It is generally recommended to drink water normally while taking Frusenex 100 Tablet . A good guideline is to drink enough water to avoid feeling thirsty for extended periods and to increase fluid intake when exercising and during hot weather. Passing pale, clear urine is a sign that you're staying properly hydrated.

Frusenex 100 Tablet is not known to cause weight gain, in contrast, it may cause weight loss due to its diuretic effects, as it helps remove excess fluid from the body. However, if you notice any weight changes, limit carbs intake, cut back on sugary drinks, exercise regularly, eat a fibre-rich diet and stay hydrated.

Do not take too much of Frusenex 100 Tablet as it may cause dizziness, headaches, a pounding or irregular heartbeat, and fainting. You may also experience increased urination and feeling of thirst. Consult the doctor immediately if you have exceeded the recommended dose or experience any of these symptoms.

Avoid foods high in salt, such as processed foods and ready to eat meals. It is not recommended to consume alcohol while taking Frusenex 100 Tablet to avoid unpleasant side effects. Eat healthy food and exercise regularly. Manage stress by doing meditation and quit smoking.

Country of origin

India

Manufacturer/Marketer address

Geno Pharmaceuticals Pvt. Ltd., Pharmaceutical Complex, Tivim Industrial Estate, Karaswada, Mapusa, Goa - 403 526
Other Info - FRU0008

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