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compositionComposition:LORAZEPAM-2MG
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Prescription Medicine
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Frezam Injection 2 ml belongs to the class of benzodiazepines. It is used in the treatment of anxiety disorder and epilepsy/fits. This medication contains lorazepam which relieves anxiety and reduces seizures by raising the gamma-aminobutyric acid (GABA), a calming chemical mediator. It also helps relax the tense muscles. Common side effects include pain, itching, swelling or redness around the injection site, drowsiness, sedation, and tiredness.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Composition :

LORAZEPAM-2MG

Consume Type :

Parenteral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Frezam Injection 2 ml

Frezam Injection 2 ml is a prescription medicine injected into the body to treat serious, continuous seizures, relieve severe acute anxiety, or produce sedation before medical procedures. It belongs to a group of medicines known as benzodiazepines, which act on the brain to produce a calming effect. Because it works rapidly, it is typically used in emergency situations or hospital settings.

Since this medicine is injected by a healthcare professional, the frequency and consistency of your treatment will be decided based on your medical condition. It is not a daily, long-term medication that you take at home. To support your recovery after receiving this medicine, it is helpful to make simple lifestyle adjustments, such as getting plenty of rest, staying hydrated, and avoiding environments with excessive noise or bright lights.

While this medicine is highly effective, it can cause common side effects such as drowsiness, dizziness, and muscle weakness. You must consult your doctor immediately if you experience serious side effects, such as unusually slow or shallow breathing, extreme sleepiness, or signs of an allergic reaction.

Before receiving this medicine, tell your doctor if you have certain health conditions. Do not take this if you have severe breathing problems, sleep apnea, a muscle weakness disorder called myasthenia gravis, or narrow-angle glaucoma. It is also not suitable for individuals with severe liver damage.

This medicine can interact dangerously with alcohol, sleeping pills, and strong pain relievers, causing extreme drowsiness or slow breathing. If you are pregnant, breastfeeding, or planning a pregnancy, talk to your doctor, as this medicine may affect your baby. Elderly individuals may be more sensitive to the effects of this medication and may require lower doses and close monitoring.

Uses of Frezam Injection 2 ml

Your doctor may prescribe Frezam Injection 2 ml to help manage the following conditions:

  • Status epilepticus (severe, continuous seizures): Frezam Injection 2 ml helps stop prolonged, life-threatening seizures quickly by calming overactive electrical activity in the brain.
  • Preanesthetic sedation: It is injected before surgery or medical procedures to relieve intense anxiety, induce sleepiness, and help you forget the stress of the procedure.
  • Acute agitation or severe anxiety: It is used in emergency situations to rapidly calm patients experiencing extreme panic, agitation, or severe anxiety.

Key Benefits

When used as directed as part of your treatment plan, this medicine may provide the following benefits:

  • Rapid relief in emergencies: Because this medicine is injected directly into a vein or muscle, it starts working within minutes. This rapid onset is crucial for stopping continuous seizures quickly, which helps prevent potential brain injury.
  • Smoother medical procedures: By inducing deep relaxation and mild forgetfulness, it helps patients undergo surgical or diagnostic procedures with significantly less anxiety and physical discomfort.
  • Effective physical and mental calming: It quickly reduces the physical symptoms of severe panic or agitation, such as a racing heart and muscle tension, allowing the patient to rest and recover safely.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of Frezam Injection 2 ml to ensure its safe and effective use.
  • Frezam Injection 2 ml will be administered by a healthcare professional in a hospital.
  • Do not self-administer this medication.

How Frezam Injection 2 ml Works

Frezam Injection 2 ml contains lorazepam, which works by enhancing the action of a natural chemical messenger in the brain called gamma-aminobutyric acid (GABA). GABA is an inhibitory neurotransmitter, which means its main job is to slow down or calm nerve activity in the central nervous system. When the medicine binds to specific receptors in the brain, it boosts GABA's calming effects. This action reduces excessive brain activity, which effectively stops seizures, relieves severe anxiety, relaxes muscles, and causes sleepiness.
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Alcohol

Unsafe

Avoid taking Frezam Injection 2 ml with alcohol as it can increase the side effects of this medicine like dizziness, drowsiness and difficulty in concentrating.

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Pregnancy

Unsafe

Frezam Injection 2 ml is considered unsafe for pregnant women. Frezam Injection 2 ml may cause harmful effects on the baby (foetus), so your doctor will weigh the benefits and potential risks before prescribing it.

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Breast Feeding

Unsafe

Frezam Injection 2 ml passes into the breast milk and may harm the baby. Avoid breastfeeding while taking Frezam Injection 2 ml.

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Driving

Unsafe

Frezam Injection 2 ml may cause sleepiness, dizziness, and drowsiness. So, it is not recommended to drive or operate machinery after taking Frezam Injection 2 ml.

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Liver

Caution

Frezam Injection 2 ml to be taken with caution, especially if you have a history of liver disease. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Frezam Injection 2 ml to be taken with caution, especially if you have a history of kidney disease. The dose may have to be adjusted by your doctor.

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Children

Unsafe

The safety and effectiveness of Frezam Injection 2 ml in children have not been established.

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Heart

Caution

Frezam Injection 2 ml should be used with caution in patients with heart conditions, as it may increase the risk of side effects. Please inform your doctor if you have any heart problems before receiving Frezam Injection 2 ml.

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Geriatrics

Caution

Frezam Injection 2 ml should be administered with caution in elderly patients due to an increased risk of side effects. Please inform your doctor before use, as the dose may need to be adjusted if required.

What if I have taken an overdose of Frezam Injection 2 ml

Since this medicine is injected by medical professionals, an overdose is rare. However, if you suspect an overdose, seek emergency medical attention immediately. Symptoms of an overdose include extreme drowsiness, severe confusion, slurred speech, slow reflexes, shallow breathing, and loss of consciousness.

Diet & Lifestyle Advise

  • Avoid Alcohol: Avoid drinking alcohol completely after receiving this medicine, as the combination can lead to dangerous breathing difficulties, severe sleepiness, or coma.
  • Limit Stimulants: Avoid drinks containing caffeine (such as coffee, tea, and energy drinks) and nicotine, as these stimulants can counteract the calming effects of the medication.
  • Avoid Falls After Injection: Ensure you have a safe environment to rest after your injection. Avoid walking unassisted, climbing stairs, or lifting heavy objects until the sedative effects have completely worn off.
  • Create a Calm Recovery Space: Keep your recovery environment quiet and dimly lit to help ease severe anxiety or recover from a seizure episode.
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How Soon It Starts Working

The time required for Frezam Injection 2 ml to start to work: Frezam Injection 2 ml ideally shows its action within a few minutes of administration. The time for which the effects of Frezam Injection 2 ml last: Frezam Injection 2 ml effect lasts for 6 to 8 hours.

What if you forget to take Frezam Injection 2 ml

Because this medicine is typically injected by a healthcare professional in a hospital as needed, it is highly unlikely that you will miss a dose. If you are on a specific injection schedule and miss an appointment, contact your healthcare provider immediately for guidance.

Storage

•Some brands may also be stored at room temperature (up to 25°C/77°F) for a limited period, typically up to 2 weeks, before use.

Drug Warnings

  • Inspect the Vial Before Use: Always inspect the vial before injection; the liquid should be clear and colourless. Do not use if the liquid is cloudy, discoloured, or contains visible particles.
  • Avoid Driving: Do not drive, operate machinery, or perform any dangerous tasks for at least 24 to 48 hours after receiving this injection, as your coordination and judgment will be temporarily impaired.
  • Report Breathing Conditions: Ensure your medical team is fully aware of your respiratory history, especially if you have asthma, chronic obstructive pulmonary disease (COPD), or sleep apnea, before you receive this injection.
  • Do Not Stop Abruptly: If you have received this medicine frequently over a long period, do not stop treatment suddenly, as this can trigger severe withdrawal symptoms. Your doctor will help you by gradually decreasing the dose.
  • Use Sterile Needles and Syringes: Make sure the healthcare provider uses a sterile, single-use needle and syringe for the injection to prevent serious infections.

verifiedApollotooltip
  • Opioid pain medicines (like codeine, tramadol, or morphine): Combining these with Frezam Injection 2 ml can cause severe drowsiness, life-threatening breathing problems, coma, or death.
  • Other central nervous system depressants (like sleeping pills, muscle relaxants, and antihistamines): These can greatly increase drowsiness and slow down your body's reactions.

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  • Alcohol: Avoid alcohol entirely, as it severely increases the risk of dangerous sedation and respiratory depression.

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Habit Forming

Yes

Therapeutic Class

[SEDATIVE-HYPNOTIC DRUGS]

FAQs

Frezam Injection 2 ml belongs to a group of medications called benzodiazepines primarily used to treat epilepsy (status epilepticus) and anxiety disorder. It may be prescribed as short-term therapy for sleeping difficulties due to anxiety. It may also be used as a sedative prior to surgery.
Frezam Injection 2 ml works by increasing levels of the chemical mediator which calms brain cells (neurons), known as gamma-aminobutyric acid (GABA), this helps relieve anxiety, stops seizures attacks (fits) and relaxes the tense muscles.
Caffeine is a stimulant that may reduce the calming effects of Frezam Injection 2 ml. So, it is advisable to avoid the intake of caffeinated beverages like coffee, tea and cola or chocolate that contain caffeine.
Elderly patients are more likely to have confusion, sleepiness or age-related health issues, which may require caution and an adjustment in the dose. So, it is better to consult a doctor if you have any concerns.
There is no clinical evidence that Frezam Injection 2 ml affects fertility in either men or women. But, if you are trying to get pregnant or having problems getting pregnant while on Frezam Injection 2 ml, consult a doctor.
Frezam Injection 2 ml is a habit-forming drug. It is not likely to be addictive if you take it for 2-4 weeks. Frezam Injection 2 ml may be habit-forming if you previously had problems with drugs or alcohol. Therefore, notify your doctor if you had problems with recreational drugs or alcohol.
Do not stop taking Frezam Injection 2 ml until instructed by your doctor. Stopping Frezam Injection 2 ml suddenly may cause side effects like confusion, depression, nervousness, sweating and diarrhoea.
No. This medicine causes significant drowsiness and slows your reflexes. You must not drive, ride a bicycle, or operate machinery for at least 24 to 48 hours after your injection. Talk to your doctor to find out when it is safe to drive again.
Dizziness is a common side effect. You should lie down immediately in a safe, comfortable place to prevent falls. Do not attempt to stand or walk without help. Talk to your doctor or nurse if the dizziness does not improve.
Yes, this medicine has a temporary effect that can cause you to forget events that happen immediately after you receive the injection. This is often helpful for reducing the stress of surgical procedures. Talk to your doctor if you have questions about this effect.
The active effects of the injection usually wear off within a few hours, but traces of the medicine can remain in your system for several days. The exact time depends on your age, liver function, and overall health. Talk to your doctor or pharmacist for more specific information.

Disclaimer

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Country of origin

India

Manufacturer/Marketer address

First Floor, House No. 860/2/FS-9, Shop No Fs-9, C.T.S. No. 178/7, 178/5, Vidharbha Premier Building 2, Empress Mall Road, Nagpur Khasa, Ghandhisagar, Nagpur-440018, Maharashtra, India
Other Info - FRE0593
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