Apollo
logo
Select Delivery Location
prescription
Prescription Medicine
info

Fotrex Combikit Tablet 24+4's is used to treat rheumatoid arthritis, psoriatic arthritis, juvenile idiopathic arthritis, psoriasis, and cancer. It contains Methotrexate and Folic acid, which work by reducing inflammation and preventing cancer cell growth. In some cases, this medicine may cause side effects such as nausea, vomiting, diarrhoea, fatigue, dizziness, headache, loss of appetite, and stomach upset. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

Read more
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
OffersOffers & Discounts

Get Free delivery (₹99) with circle icon

Join Circle
coupon
Get Extra 18% Off with Coupons
coupon
Extra 10% Off with Bank Offers
bank offer
bank offer
bank offer

More about the Product

Manufacturer/Marketer :

Alena Lifesciences Llp

Consume Type :

Oral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Fotrex Combikit Tablet 24+4's

Fotrex Combikit Tablet 24+4's is an oral medicine prescribed to treat severe inflammatory conditions, including rheumatoid arthritis and severe psoriasis. It helps manage these conditions by calming an overactive immune system and slowing down rapid cell growth. This medicine is designed to control chronic symptoms and prevent long-term damage to your joints and skin.

Unlike daily medications, Fotrex Combikit Tablet 24+4's must be taken on a strict weekly schedule as directed by your doctor. It can be taken with or without food, but taking your dose after a meal can help reduce potential stomach upset. To get the best results from your treatment, it is important to stay well-hydrated and follow a balanced diet rich in fresh vegetables and lean proteins.

While this medicine is highly effective, some patients may experience mild side effects like nausea, fatigue, or temporary hair thinning. You should contact your doctor immediately if you experience serious side effects, such as signs of infection, breathing difficulties, or yellowing of your skin or eyes. Regularly monitoring your health with blood tests is an essential part of this treatment.

Before starting Fotrex Combikit Tablet 24+4's, tell your doctor about your complete medical history, especially if you have liver, kidney, or lung conditions. Do not take this if you are pregnant, planning to become pregnant, breastfeeding, or have severe liver damage or pre-existing low blood counts. It is crucial to use reliable contraception while taking this medication.

This medicine can interact with several other substances, including alcohol, which significantly increases your risk of liver damage. It can also interact with certain pain relievers and antibiotics, so you must discuss all your current medications with your healthcare provider. Elderly individuals may be more sensitive to side effects and may require a gradually increasing dose under close medical supervision.

Uses of Fotrex Combikit Tablet 24+4's

Fotrex Combikit Tablet 24+4's is used in the treatment of severe inflammatory conditions such as rheumatoid arthritis, psoriasis, and psoriatic arthritis. The detailed uses of Fotrex Combikit Tablet 24+4's are as follows:

  • Rheumatoid arthritis: Fotrex Combikit Tablet 24+4's helps reduce swelling, pain, and stiffness in the joints, while protecting them from progressive, permanent damage.
  • Severe psoriasis: Fotrex Combikit Tablet 24+4's treats severe, widespread skin plaques by slowing down the rapid overproduction of skin cells.
  • Psoriatic arthritis: Fotrex Combikit Tablet 24+4's helps manage both the joint inflammation and painful skin symptoms associated with this condition.

Key Benefits

Fotrex Combikit Tablet 24+4's offers targeted relief for chronic inflammatory conditions, helping you maintain a better quality of life. By addressing the root cause of inflammation, it provides the following key benefits:

  • Reduces joint swelling and tenderness, making it easier to perform daily activities with greater comfort and mobility.
  • Helps reduce the size, redness, and itching of severe psoriasis plaques, promoting healthier-looking skin.
  • Slows the progression of joint damage, helping protect your bones and cartilage over the long term.
  • The addition of folic acid helps protect healthy cells in your body, reducing common treatment-related side effects such as mouth sores and nausea.
Side effects of Fotrex Combikit Tablet 24+4's
  • Boost your immunity by including immune rich foods in your diet and always remember to stay hydrated.
  • Get sufficient sleep and manage stress which helps in improving white blood cell count.
  • Consult your doctor for an effective treatment to improve the blood cell count and get regular body check up to monitor changes in the count.
  • Try to prevent the factors that cause a decrease in white blood cells which may lead to impaired immunity.
  • Eat protein-rich foods like fish, poultry, eggs, and legumes.
  • Include foods with minerals and vitamins essential for hair health.
  • Join a support group to connect with others experiencing hair loss.
  • Openly discuss your feelings about hair loss.
  • Consider covering up with wigs, hats, or scarves.
  • Be patient and avoid seeking miracle cures.

Directions for Use

  • Take Fotrex Combikit Tablet 24+4's with or without food, or as advised by a doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow the medicine as a whole with a glass of water.
  • Do not crush, break, or chew it.

How Fotrex Combikit Tablet 24+4's Works

Fotrex Combikit Tablet 24+4's contains two active components that work together to treat your condition while minimising side effects. Methotrexate: It is an immunosuppressant that targets rapidly dividing cells. In conditions like rheumatoid arthritis and psoriasis, your immune system is overactive and attacks healthy tissues, causing rapid cell buildup. Methotrexate calms this immune response and slows down the rapid production of inflammatory cells in your joints and skin. Because methotrexate targets fast-growing cells, it can also affect normal, healthy cells in your body, such as those in your mouth and digestive tract.
bannner image

Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Fotrex Combikit Tablet 24+4's. It could lead to increased dizziness and drowsiness.

bannner image

Pregnancy

Unsafe

Fotrex Combikit Tablet 24+4's is not recommended and unsafe in pregnancy. It can affect and harm the developing baby. You are advised to get a pregnancy test done before starting Fotrex Combikit Tablet 24+4's. You should get a negative pregnancy test for sure before using Fotrex Combikit Tablet 24+4's. Also, please use reliable forms of birth control if you are undergoing treatment with Fotrex Combikit Tablet 24+4's to avoid pregnancy.

bannner image

Breast Feeding

Unsafe

Fotrex Combikit Tablet 24+4's is excreted into the breast milk and is not recommended during breastfeeding. Please consult your doctor before taking Fotrex Combikit Tablet 24+4's if you are a breastfeeding mother.

bannner image

Driving

Caution

Fotrex Combikit Tablet 24+4's may sometimes make you feel dizzy. Do not drive or operate machinery if you are not mentally alert and focused.

bannner image

Liver

Caution

Let your doctor know if you have any history of liver disease before taking Fotrex Combikit Tablet 24+4's. Your dosage may be adjusted in case of liver impairment.

bannner image

Kidney

Caution

Let your doctor know if you have any history of kidney disease before taking Fotrex Combikit Tablet 24+4's. Your dosage may be adjusted in case of renal impairment.

bannner image

Children

Caution

Fotrex Combikit Tablet 24+4's may be given to children for psoriasis treatment. However, it should not be used by children under three years of age, as efficacy and safety have not been established.

bannner image

Heart

Caution

Fotrex Combikit Tablet 24+4's should be taken with extreme caution in patients with heart disease. Please consult your physician.

bannner image

Geriatrics

Safe if prescribed

Fotrex Combikit Tablet 24+4's is safe for use in elderly patients if prescribed by the physician.

What if I have taken an overdose of Fotrex Combikit Tablet 24+4's

If you or someone else accidentally takes more than the prescribed dose of Fotrex Combikit Tablet 24+4's, or takes it daily instead of weekly, seek emergency medical attention or contact a poison control centre immediately. An overdose can lead to severe complications affecting your blood cells and digestive system.

Diet & Lifestyle Advise

  • Stay hydrated: Drink at least 8 to 10 glasses of water daily. Staying well-hydrated helps your kidneys flush out the medication efficiently, reducing the risk of kidney strain.
  • Avoid alcohol entirely: Combining alcohol with this medicine significantly increases the risk of severe liver damage. It is safest to avoid all alcoholic beverages during your treatment.
  • Limit caffeine intake: Avoid drinking large amounts of coffee, black tea, or energy drinks, especially on the days you take your methotrexate dose, as caffeine can reduce the effectiveness of the treatment.
  • Practice strict sun safety: This medicine can make your skin highly sensitive to sunlight. Wear a broad-spectrum sunscreen (SPF 30 or higher), protective clothing, and a wide-brimmed hat whenever you go outdoors.
  • Maintain excellent oral hygiene: Use a soft-bristled toothbrush and rinse your mouth regularly with water to prevent and soothe mild mouth sores.
health query

Have a query?

How Soon It Starts Working

The time required for Fotrex Combikit Tablet 24+4's to start to work: The time required for Fotrex Combikit Tablet 24+4's to show its action is unknown. The time for which the effects of Fotrex Combikit Tablet 24+4's last: The duration of action for Fotrex Combikit Tablet 24+4's is clinically unknown.

What if you forget to take Fotrex Combikit Tablet 24+4's

If you miss your scheduled dose of Fotrex Combikit Tablet 24+4's, do not take a double dose to make up for the missed one. Because this medicine is taken on a strict weekly schedule, missing a dose requires careful handling. Talk to your doctor or pharmacist immediately to get specific advice on when to take your next dose.

Storage

•Store Fotrex Combikit Tablet 24+4's at controlled room temperature, between 20°C and 25°C (68°F to 77°F). •Keep the tablets in their original container or blister pack to protect them from direct light and moisture. Do not store them in humid environments like bathroom cabine

Drug Warnings

  • Use a calendar: Always mark your dosing days clearly on a calendar to avoid taking this weekly medication on consecutive days, which can cause severe toxicity.
  • Verify your schedule: Double-check your prescription bottle before taking each dose to make sure you are taking the correct tablet on the correct day.
  • Use highly effective birth control: Both men and women must use reliable contraception during treatment and for at least six months after stopping, as this medicine can cause severe birth defects.
  • Avoid live vaccines: Do not receive live vaccines (such as the shingles, measles, or yellow fever vaccines) while taking this medicine, as your immune system may be too weak to handle them safely.
  • Keep your blood test appointments: You must complete all scheduled routine blood tests so your doctor can regularly check your liver damage markers, kidney function, and blood cell counts.

Drug-Drug Interactions

verifiedApollotooltip
  • Nonsteroidal Anti-inflammatory Drugs (e.g., ibuprofen, naproxen): Pain relievers can slow down the removal of methotrexate from your body, increasing the risk of severe side effects.
  • Certain Antibiotics (e.g., penicillin, trimethoprim): These medicines can raise methotrexate levels in your blood, increasing its toxicity.
  • Proton Pump Inhibitors (e.g., omeprazole): Acid-reducing medications can delay the clearance of methotrexate from your system.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

Login/Sign Up

Drug-Food Interactions

verifiedApollotooltip
  • Alcohol: Drinking alcohol while on this medication significantly raises the risk of severe liver damage.
  • Caffeine: Consuming large amounts of coffee, tea, or colas can interfere with how well methotrexate works to control your symptoms.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

Login/Sign Up

All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIRHEUMATICS]

FAQs

Fotrex Combikit Tablet 24+4's is used to treat rheumatoid arthritis, psoriatic arthritis, juvenile idiopathic arthritis, psoriasis, and cancer.
Fotrex Combikit Tablet 24+4's contains Methotrexate and Folic acid. Methotrexate acts as an immunosuppressant by suppressing the overactive immune system that causes inflammation. It also interferes with DNA synthesis and slows the growth of rapidly dividing cells, helping treat autoimmune conditions such as rheumatoid arthritis, psoriasis, psoriatic arthritis, and certain cancers. Folic acid helps replace the folic acid depleted by methotrexate, reducing side effects without affecting its effectiveness.
Diarrhoea might be a side-effect of Fotrex Combikit Tablet 24+4's. Drink lots of fluids and eat foods rich in fibre if you experience diarrhoea. If you find blood in your stools (tarry stools) or experience excess diarrhoea, consult your doctor. Do not take anti-diarrhoeal medicine on your own.
Fotrex Combikit Tablet 24+4's should be used with caution if you have a medical history of liver or kidney diseases, lung diseases (pulmonary fibrosis), alcohol use, suppressed immune system, blood cell/bone marrow disorders, gastrointestinal diseases (peptic ulcer, ulcerative colitis) and active infections (including chickenpox).
Yes. Methotrexate in Fotrex Combikit Tablet 24+4's suppresses the immune system to reduce inflammation. It can also lower white blood cell counts (leukopenia), making you more susceptible to infections. Avoid close contact with people who have active infections and consult your doctor immediately if you develop fever, sore throat, breathlessness, jaundice, or unexplained bleeding or bruising.
The primary component, methotrexate, is a powerful medicine that is highly effective when taken once weekly. Taking it daily can lead to severe, life-threatening toxicity. Always follow your doctor's exact weekly schedule. Talk to your doctor if you are confused about your dosing calendar.
No, you should not take this medicine if you are pregnant or planning to conceive. It can cause severe birth defects or pregnancy loss. Both men and women must use effective contraception during treatment and for several months afterwards. Talk to your doctor about safe family planning options.
Methotrexate blocks folic acid inside cells to stop inflammation, but this can also affect your healthy cells. Taking folic acid on non-methotrexate days helps protect your healthy cells, reducing side effects like mouth sores and nausea without stopping the medicine from working. Talk to your doctor for a personalised schedule.
Taking this medication daily instead of weekly is a medical emergency. Seek immediate emergency medical attention or contact a poison control centre right away, even if you do not feel sick. Talk to your doctor immediately if you make a dosing mistake.
No, you should completely avoid alcohol during your treatment. Both alcohol and methotrexate are processed by the liver, and combining them greatly increases your risk of developing severe liver damage. Talk to your doctor or pharmacist if you need help managing this lifestyle change.
You can safely receive inactive vaccines, such as the standard flu shot. However, you must avoid live vaccines (like the shingles or yellow fever vaccines) while taking this medicine, as your weakened immune system may not react safely to them. Talk to your doctor before scheduling any vaccination.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

1102 KAILAS CORPORATE LOUNGE PREM. CHS. LTD.VEER SAVARKAR MARG, VIKROLI PARKSITE, VIKROLI WEST Mumbai, Maharashtra, India - 400079
Other Info - FOT0018
whatsapp Floating Button
Buy Now
Add to Cart