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  3. Fonyl 4gm Injection

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Fonyl 4gm Injection, Pack of 1 Injection
Fonyl 4gm Injection, Pack of 1 Injection
Fonyl 4gm Injection, Pack of 1 Injection
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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Fonyl 4gm Injection is an antibiotic medicine, used in the treatment of bacterial infections of bones and joints, heart, lungs, central nervous system, stomach, blood, skin, and tissues below the skin, bacterial meningitis, complicated urinary tract infections. This medicine works by stopping the growth of bacteria and thereby helps reduce various bacterial infections. It will be administered by the doctor in hospital.
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Synonym :

FOSFOMYCIN SODIUM

Composition :

FOSFOMYCIN-4GM

Manufacturer/Marketer :

Glenmark Pharmaceuticals Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Fonyl 4gm Injection

Fonyl 4gm Injection belongs to a class of drugs called antibiotics used in the treatment of bacterial infections. Fonyl 4gm Injection is used to treat bacterial meningitis (infection of membranes protecting the brain and spinal cord), complicated urinary tract infections, bacterial infections of bones and joints, heart, lungs, central nervous system, stomach, blood, skin, and tissues below the skin. Bacterial infection is a condition in which harmful bacteria grow in the body and cause infection. It can infect any part of the body and multiply very quickly.

Fonyl 4gm Injection contains Fosfomycin which works by inhibiting the formation of the bacterial cell walls (a protective covering) that is necessary for their survival. Thereby killing bacteria. Also, Fonyl 4gm Injection decreases the attachment of bacteria to cells lining the urinary bladder.

Fonyl 4gm Injection will be administered by a healthcare professional. Do not self-administer. You may sometimes experience gastrointestinal disturbances, taste disturbances, or injection site reactions. Most of these side effects of Fonyl 4gm Injection do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. 

If you are allergic to Fosfomycin or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, please inform your doctor before taking Fonyl 4gm Injection. Fonyl 4gm Injection could be used in children if prescribed by a doctor; the dose depends on the child’s age and weight. If you have experienced diarrhoea after receiving or taking antibiotics, inform your doctor before taking Fonyl 4gm Injection. If you have kidney problems or are undergoing dialysis, inform your doctor as the dose may be reduced. 

Uses of Fonyl 4gm Injection

Treatment of Bacterial infections

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Directions for Use

• Fonyl 4gm Injection is administered only by qualified healthcare professionals, usually through intravenous infusion in a hospital or clinic setting.• This medication must not be self-administered, as it requires careful dosing, preparation, and monitoring.• It is important to complete the full course of treatment as prescribed, even if symptoms improve, to prevent recurrence or resistance.

Medicinal Benefits

Fonyl 4gm Injection contains Fosfomycin, a broad-spectrum antibiotic that kills gram-negative and gram-positive bacteria that grow aerobically (in the presence of oxygen) and anaerobically (in the absence of oxygen). Bacterial meningitis (infection of the membranes that protect the brain and spinal cord), complicated urinary tract infections, bacterial infections of bones and joints, heart, lungs, central nervous system, stomach, blood, skin, and tissues beneath the skin are all treated with Fonyl 4gm Injection. Fosfomycin should be used only when other antibiotics have failed or are ineffective. Fonyl 4gm Injection prevents bacterial cell wall formation (a protective covering required for survival). Bacteria are thus killed. Additionally, Fonyl 4gm Injection reduces the attachment of bacteria to the cells lining the urinary bladder.

How Fonyl 4gm Injection Works

Fonyl 4gm Injection contains Fosfomycin which works by inhibiting the formation of the bacterial cell walls (a protective covering) that is necessary for their survival. Thereby killing bacteria. Also, Fonyl 4gm Injection decreases the attachment of bacteria to cells lining the urinary bladder.

Storage

• Store in a cool and dry place away from sunlight.• Keep Fonyl 4gm Injection out of reach and sight of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Fonyl 4gm Injection
  • Regularly brush and floss your teeth.
  • Rinse your mouth with water and baking soda a solution to neutralize acid in the mouth. This makes your food taste as it should.
  • Drink plenty of water or non-caffeinated drinks to prevent dry mouth which may lead to altered taste.
  • Try ginger, peppermint, fruit or green teas, lemonade, ginger ale or fruit juice to help mask unpleasant tastes.
  • Try sucking on sugar-free ice pops or ice cubes to prevent dry mouth.
  • Talk to your doctor about oral potassium supplements.
  • Eat potassium rich foods such as bananas, avocados, oranges, dark leafy greens, beans and peas, fish, spinach, milk and tomatoes.
  • Red rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
  • Use a warm compress on the affected area to help reduce discomfort.
  • Elevate the affected limb above heart level.
  • Remove the IV catheter (if applicable) and reinsert at a different site.
  • Consult your healthcare provider if symptoms are severe or persist.

What if I have taken an overdose of Fonyl 4gm Injection

Fonyl 4gm Injection is administered by a healthcare professional in a hospital setting. Hence, the chances of overdose are less. Overdose of this medicine may cause hearing loss and metallic taste. Your doctor may take immediate necessary action if an overdose is suspected.

Drug Warnings

If you are allergic to Fosfomycin or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, please inform your doctor before taking Fonyl 4gm Injection. Fonyl 4gm Injection may be used with caution in children if prescribed by a doctor; the dose depends on the child’s age and weight. If you had diarrhoea previously after receiving or taking antibiotics, inform your doctor before taking Fonyl 4gm Injection. If you have kidney problems or are undergoing dialysis, inform your doctor, as the dose may be reduced. 

Drug-Drug Interactions

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FosfomycinBCG vaccine
Severe
FosfomycinBalsalazide
Severe

Drug-Drug Interactions

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FosfomycinBCG vaccine
Severe
How does the drug interact with Fonyl 4gm Injection:
When BCG vaccine is used with Fonyl 4gm Injection, its effectiveness may be reduced.

How to manage the interaction:
Taking Fonyl 4gm Injection with the BCG vaccine can lead to an interaction, please consult a doctor before taking it.
FosfomycinBalsalazide
Severe
How does the drug interact with Fonyl 4gm Injection:
Fonyl 4gm Injection may reduce the effect of balsalazide when taken orally.

How to manage the interaction:
If you are supposed to take Fonyl 4gm Injection and Balsalazide together, your doctor may adjust the dose or monitor you more frequently to use both medications safely.
FosfomycinCholera vaccines
Severe
How does the drug interact with Fonyl 4gm Injection:
Co-administration of the Cholera vaccine with Fonyl 4gm Injection may reduce the activity of the Cholera vaccine.

How to manage the interaction:
If you are currently being treated with Fonyl 4gm Injection or have been treated within the last 14 days, inform your doctor before receiving cholera vaccine, live. Avoid receiving cholera vaccine, live until at least 14 days after you complete your antibiotic therapy to ensure adequate vaccine response.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Take probiotics after completing the full course of Fonyl 4gm Injection in order to restore some healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like cheese, yoghurt, kombucha, sauerkraut and kimchi can help restore the intestine's good bacteria. 

  • Include fibre-rich foods, as they can be easily digested by your gut bacteria, which helps stimulate their growth. Thus, fibre-rich foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains such as whole-grain bread and brown rice should be included in your diet. 

  • Maintain a low-sodium diet as Fonyl 4gm Injection in injection form may increase sodium levels in the blood.

  • Make sure you drink plenty of water or other fluids daily while you are taking Fonyl 4gm Injection.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS

Fonyl 4gm Injection Substitute

Substitutes safety advice
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Alcohol

Caution

The interaction of alcohol with Fonyl 4gm Injection is unknown. Hence, avoid or limit alcohol consumption while on treatment with Fonyl 4gm Injection.

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Pregnancy

Safe if prescribed

Fonyl 4gm Injection is considered safe to be used in pregnancy. However, if you are pregnant, inform your doctor before receiving Fonyl 4gm Injection. Your doctor prescribes this medicine if the benefits outweigh the risks.

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Breast Feeding

Safe if prescribed

Small amounts of Fonyl 4gm Injection are excreted in human milk. Therefore, it is given to breastfeeding mothers only if the doctor thinks the benefits are greater than the risks.

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Driving

Caution

Fonyl 4gm Injection may cause weakness or confusion in some people. Therefore, avoid driving if you notice any of these symptoms after taking Fonyl 4gm Injection.

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Liver

Caution

Please consult a doctor if you have a history of liver diseases/conditions.

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Kidney

Caution

Take Fonyl 4gm Injection with caution, especially if you have a history of kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Fonyl 4gm Injection may be used with caution in children if prescribed by a doctor, and the dose depends on the child’s age and weight.

FAQs

Fonyl 4gm Injection belongs to a class of drugs called antibiotics used in the treatment of bacterial infections. Fonyl 4gm Injection is used to treat bacterial meningitis (infection of membranes protecting the brain and spinal cord), complicated urinary tract infections, bacterial infections of bones and joints, heart, lungs, central nervous system, stomach, blood, skin, and tissues below the skin.

Fonyl 4gm Injection contains Fosfomycin, which inhibits the formation of the bacterial cell wall (a protective covering) necessary for survival. Thereby killing bacteria. Also, Fonyl 4gm Injection decreases the attachment of bacteria to cells lining the urinary bladder.

Fonyl 4gm Injection may cause taste disturbances as a temporary side effect. However, if the condition persists or worsens, please inform your doctor.

If you are undergoing dialysis or have kidney problems, inform your doctor before receiving Fonyl 4gm Injection so that the dose may be adjusted.

Fonyl 4gm Injection may cause diarrhoea as a rare side effect. However, if the condition persists or worsens with fever or severe stomach pain, please consult a doctor immediately, as these might be signs of large intestine infection.

You are not recommended to take blood thinner while receiving Fonyl 4gm Injection as co-administration of these two medicines may alter the blood thinner's ability to prevent blood from clotting. However, please consult your doctor before taking other medicines while receiving Fonyl 4gm Injection.

The side effects of Fonyl 4gm Injection include injection site reactions, taste disturbances and gastrointestinal disturbances. If these side effects persist or worsen, please consult your doctor.

Fonyl 4gm Injection is a broad-spectrum antibiotic which affects and damages the cell wall (covering of bacteria) synthesis. Thereby, it kills the infection causing bacteria. Additionally, Fonyl 4gm Injection prevents the attachment of bacteria to superficial cells of urinary bladder, hence preventing infection.

The dosing schedule is decided by your doctor and the dose depends on bacteria causing the infection, site and severity of the infection. Your doctor will consider your body weight, age, and status of kidney function while deciding the dose and duration.

As Fonyl 4gm Injection is eliminated by the kidneys, the time for which Fonyl 4gm Injection stays in the body depends upon how well kidney functions. In healthy adults, about 80-90% of the total medication injected is excreted by kidneys within 10 hours following a single injection into the veins. The medicine may remain for a longer time in the body if the patient has kidney dysfunction.

Country of origin

India

Manufacturer/Marketer address

Glenmark Pharmaceuticals Limited, B/2, Mahalaxmi Chambers, 22, Bhulabhai Desai Road, Mumbai – 400 026.
Other Info - FON0016

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 7:01 AM IST

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Reference

  1. https://www.medicines.org.uk/emc/product/11249/smpc
  2. https://ec.europa.eu/health/documents/community-register/2020/20200609148048/anx_148048_en.pdf
  3. https://www.ciplamed.com/content/crifos-4-gm-injection

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