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Folbact 1.5gm Injection is used to treat various bacterial infections of the lungs, urinary tract, blood, brain and spinal cord (meningitis), skin, abdomen, bones, joints, and certain sexually transmitted infections like gonorrhoea. It helps control and clear infections, reduce symptoms, prevent bacterial spread, and support faster recovery.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Folbact 1.5gm Injection

Folbact 1.5gm Injection is an injectable combination medicine used to treat a wide variety of severe bacterial infections. It is prescribed for infections affecting the lungs, urinary tract, skin, abdomen, and bloodstream. This medicine works by targeting and destroying the bacteria causing the illness, helping you recover from severe infections.

Because this medication is given by injection or infusion, your healthcare provider will determine how often you receive it. It is highly important to receive this medicine at consistent, regularly spaced intervals to keep a steady amount in your body. To support your recovery while on this treatment, drink plenty of water, get plenty of rest, and eat simple, nutritious meals.

While using it, you may experience some common side effects like mild diarrhoea, nausea, or swelling at the injection site. However, you must contact your doctor immediately if you experience severe symptoms, such as watery or bloody diarrhoea, a high fever, or a sudden skin rash.

Before you start treatment, you should tell your doctor if you have kidney disease, liver damage, or a history of bleeding problems. Do not take this if you have ever had a severe allergic reaction to penicillin or cephalosporin antibiotics.

Let your doctor know about all other medicines you are taking, as some can interact with it and increase your risk of bleeding or kidney issues. Avoid drinking alcohol during and shortly after your treatment because it can cause a severe, uncomfortable physical reaction.

If you are pregnant, breastfeeding, or managing health conditions in your older years, talk to your doctor or pharmacist to ensure this medicine is safe for you. This medicine should be used in children only under the supervision of a paediatrician, as the dose and duration depend on the child's age, weight, and the type of infection.

Uses of Folbact 1.5gm Injection

Your doctor may recommend this medicine to help manage the following conditions:

  • Severe lung infections: It helps clear deep chest infections like pneumonia by killing the responsible bacteria.
  • Abdominal infections: It targets bacterial growth in the stomach and abdomen, helping to heal conditions like peritonitis.
  • Urinary tract infections: It treats complicated infections of the bladder and kidneys, resolving pain and irritation.
  • Skin and soft tissue infections: It controls and eliminates bacterial infections in deep skin layers, preventing them from spreading.
  • Bloodstream infections: It helps treat life-threatening blood infections, also known as sepsis, by clearing bacteria directly from the circulation.

Key Benefits

When taken consistently as directed, this medicine may provide the following health benefits:

  • Treats serious bacterial infections: Helps eliminate bacteria responsible for severe infections, supporting effective treatment and recovery.
  • Provides rapid antibiotic action: As an injectable medicine, it delivers the antibiotic directly into the body, allowing it to begin working quickly against the infection.
  • Relieves infection-related symptoms: As the infection improves, it helps reduce symptoms such as fever, pain, and tiredness, helping you feel better.
  • Supports recovery and prevents complications: By controlling the infection early, it helps reduce the risk of the infection spreading and supports a smoother recovery.
Side effects of Folbact 1.5gm Injection
  • Talk to your doctor about medicines to manage neutropenia based on the underlying cause.
  • Avoid contact with people who are sick.
  • Wash your hands regularly with soap and water.
  • Avoid unpasteurized dairy products.
  • Boost your immunity by including immune rich foods in your diet and always remember to stay hydrated.
  • Get sufficient sleep and manage stress which helps in improving white blood cell count.
  • Consult your doctor for an effective treatment to improve the blood cell count and get regular body check up to monitor changes in the count.
  • Try to prevent the factors that cause a decrease in the white blood cells that may lead to impaired immunity.
  • Stay hydrated by taking fluids like water, juices and soups etc.
  • Eat fruits and vegetables which contain vitamins.
  • Take iron rich food like dry fruits, green leafy vegetables and sea food etc.
  • Reduce intake of milk, cheese, yogurt, soy, chocolate, ice cream, Grapes, Popcorn, canned salmon, pomegranate.
  • Regular exercise like walking, jogging is helpful.
  • Inform your doctor if you experience low hematocrit symptoms such as exhaustion, weakness, or pale complexion. Your doctor will diagnose the problem and recommend appropriate treatment.
  • Increase iron intake with iron-rich foods like red meat, poultry, fish, beans, and fortified cereals.
  • Consume vitamin C-rich foods such as citrus fruits, bell peppers, and tomatoes to improve iron absorption.
  • Avoid tea and coffee since they can interfere with iron absorption.
  • Don't smoke because it lowers the creation of red blood cells.
  • Consume beetroot juice, as it is rich in iron and supports red blood cell production.
  • Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
  • Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
  • Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
  • Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
  • If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
  • In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
  • Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
  • If you experience severe bleeding or bruising, seek emergency medical attention immediately.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Folbact 1.5gm Injection will be administered by the doctor or healthcare professional.
  • Do not self-administer.

How Folbact 1.5gm Injection Works

This medicine works using a dual-action approach. Cefoperazone sodium and Sulbactam combine two active ingredients that cooperate to defeat tough bacterial infections. Cefoperazone sodium acts as the main fighter. It targets the bacteria directly by interfering with the construction of their protective outer cell walls. Without this wall, the bacteria cannot survive and eventually burst and die. Sulbactam serves as a protector. Some bacteria produce special enzymes designed to break down and destroy antibiotics, rendering them useless. This second ingredient blocks those bacterial enzymes, shielding the main fighter so it can do its job effectively. Together, they ensure the medicine remains highly active and reliable against even resistant bacteria.
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Alcohol

Unsafe

Avoid consuming alcohol while taking Folbact 1.5gm Injection as it may cause flushing, sweating, headache and a fast heart rate.

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Pregnancy

Consult your doctor

If you are pregnant, please consult your doctor; your doctor will prescribe Folbact 1.5gm Injection only if the benefits outweigh the risks.

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Breast Feeding

Caution

Folbact 1.5gm Injection may pass into breastmilk. Therefore, Folbact 1.5gm Injection should be administered with caution in breastfeeding mothers.

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Driving

Safe if prescribed

Folbact 1.5gm Injection is unlikely to affect your ability to drive.

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Liver

Consult your doctor

Please consult your doctor before taking Folbact 1.5gm Injection if you have liver impairment/liver disease.

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Kidney

Consult your doctor

Please consult your doctor if you have any concerns regarding this or if you have kidney impairment/kidney disease before taking Folbact 1.5gm Injection.

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Children

Safe if prescribed

Folbact 1.5gm Injection is safe to be used in children if recommended by a doctor. The dose may vary depending on the child's weight.

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Heart

Caution

Folbact 1.5gm Injection should be administered with caution in patients with heart problems. Therefore, please talk to your doctor before receiving Folbact 1.5gm Injection.

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Geriatrics

Caution

Folbact 1.5gm Injection should be administered with caution in elderly patients due to an increased risk of side effects.

What if I have taken an overdose of Folbact 1.5gm Injection

An overdose of this medicine is rare when given by a trained professional. If you suspect an overdose or experience severe muscle twitches, seizures, or confusion, seek immediate emergency care.

Diet & Lifestyle Advise

  • Stay well-hydrated: Drink plenty of water and other fluids to support your body's recovery and help your kidneys process the medicine.
  • Support gut health: After completing your antibiotic course, include probiotic-rich foods, such as yoghurt or kefir, to help restore the natural balance of healthy gut bacteria.
  • Avoid alcohol: Do not drink alcohol during treatment and for at least 3 days after your last dose, as it may cause a severe reaction, including flushing, nausea, vomiting, headache, and a rapid heartbeat.
  • Get adequate rest: Rest well and avoid strenuous activities to help your immune system fight the infection and support recovery.
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How Soon It Starts Working

  • The time required for Folbact 1.5gm Injection to start to work: Folbact 1.5gm Injection effect can be observed rapidly after administration.
  • The time for which the effects of Folbact 1.5gm Injection last: The duration of Folbact 1.5gm Injection’s effect is clinically not established.

What if you forget to take Folbact 1.5gm Injection

Since this medication is usually given by a healthcare provider in a clinical setting, missing a dose is unlikely. However, if you are receiving this treatment at home and miss a scheduled dose, contact your healthcare provider immediately for instructions. Do not double the dose to catch up.

Storage

• Store the dry powder vials at room temperature, below 25°C.

Drug Warnings

  • Avoid alcohol: Do not drink alcohol while taking this medicine and after your last injection, as it may cause flushing, headache, nausea, vomiting, and a rapid heartbeat.
  • Inspect the injection before use: Do not use the injection if the solution is cloudy, discoloured, or contains visible particles.
  • Use proper injection technique: If you are administering this injection at home, use a new sterile needle and syringe for each dose and rotate injection sites to help reduce skin irritation.
  • Report severe diarrhoea: Tell your doctor immediately if you develop severe, persistent, watery, or bloody diarrhoea, even if it occurs several weeks after completing treatment.
  • Inform your doctor about blood thinners: Tell your healthcare provider if you are taking blood-thinning medicines (anticoagulants), as this medicine may increase the risk of bleeding or affect blood clotting.
  • Complete the prescribed treatment: Continue using this medicine for the full course prescribed by your doctor, even if you start feeling better, to help clear the infection completely and reduce the risk of antibiotic resistance.
  • Follow up if symptoms persist: Contact your doctor if your symptoms do not improve or worsen during treatment, as your condition may need to be reassessed.

Drug-Drug Interactions

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  • Blood thinners (like warfarin): May increase the risk of bleeding. Your doctor may need to monitor your blood clotting times closely.
  • Water pills (diuretics) and other strong antibiotics (like aminoglycosides): Combining these with it may increase the strain on your kidneys.
     
Critical

Drug-Drug Interactions

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Critical
How does the drug interact with Folbact 1.5gm Injection:
When BCG vaccine is used with Cefoperazone, its effectiveness may be reduced.

How to manage the interaction:
Taking cefoperazone with BCG vaccine is not recommended, but can be taken together if prescribed by a doctor. However, consult your doctor if you experience any unusual symptoms. To ensure an adequate response to your cancer treatment, you should not receive BCG until after you complete your antibiotic therapy. Do not discontinue any medications without consulting a doctor
How does the drug interact with Folbact 1.5gm Injection:
Taking Cefoperazone and Rifampicin together may increase the risk of bleeding.

How to manage the interaction:
Although there is an interaction between cefoperazone and rifampicin, they can be taken together if prescribed by a doctor. However, if you experience vomiting, blood in your urine or stools, headache, dizziness, or weakness, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • Alcohol: Interacts severely with this medication, causing rapid heart rate, severe sweating, facial flushing, and vomiting. Avoid alcohol entirely during and after treatment.
     
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTI- BACTERIALS]

FAQs

Folbact 1.5gm Injection belongs to the group of medicines called antibiotics used to treat various bacterial infections such as respiratory tract infection, urinary tract infection, blood infection, meningitis (inflammation of the brain and spinal cord), gonorrhoea (sexually transmitted disease), skin and soft tissue infections, abdominal infections, bone and joint infections, genital tract infections, and endometritis (infection in the uterus).
Folbact 1.5gm Injection contains Cefoperazone sodium and Sulbactam. Cefoperazone sodium works by preventing the formation of bacterial cell covering, which is necessary for their survival. Thereby killing the bacteria. Sulbactam works by decreasing bacterial resistance and enhancing the activity of Cefoperazone sodium against the bacteria. Together, Folbact 1.5gm Injection helps to treat bacterial infections.
Inform your doctor if you do not feel better even after finishing the full course of treatment. If the symptoms worsen while using this medicine, consult your doctor.
Folbact 1.5gm Injection may cause Clostridium difficile-associated diarrhoea (CDAD). Treatment with antibiotics alters the normal flora, leading to overgrowth of Clostridium difficile; this causes diarrhoea. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience prolonged diarrhoea with abdominal pain, stop taking Folbact 1.5gm Injection and consult your doctor. Do not take anti-diarrheal medicine on your own.
The common side effects of Folbact 1.5gm Injection may include diarrhoea, nausea, vomiting, headache, rash, and injection site reactions. Most of these side effects of Folbact 1.5gm Injection do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.
It is given as an injection directly into a vein (intravenous) or into a large muscle (intramuscular) by a healthcare professional. Talk to your doctor if you have questions about your specific treatment plan.
No, you must avoid alcohol during treatment and for at least three days after your final dose. Alcohol can cause a severe, uncomfortable reaction including headaches, sweating, and rapid heartbeats. Talk to your doctor if you need advice on managing this.
It should only be used during pregnancy if your doctor determines it is necessary. Always inform your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding. Talk to your doctor to understand the risks and benefits.
No, it is an antibiotic and only works against infections caused by bacteria. It will not work against viral infections like the cold or flu. Talk to your doctor if you are unsure about the cause of your illness.
Some mild pain, redness, or swelling at the injection site is common and usually resolves on its own. However, if the pain becomes severe, warm to the touch, or starts oozing, contact your healthcare provider right away. Talk to your doctor if you experience any worsening discomfort.

Disclaimer

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Country of origin

INDIA

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - FOL0366
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