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Flures 20% w/v Injection 3 ml is used in eye examinations as a diagnostic agent. It contains the active ingredient fluorescein sodium, a diagnostic stain; this will assist your doctor in diagnosing diseases that affect these blood vessels, especially in elderly people and diabetics. Common side effects of Flures 20% w/v Injection 3 ml may include pain at the injection site, nausea, vomiting, redness and itching of the skin, discolouration (yellowing) of the skin and eyes, discolouration (yellowing) of the urine and abdominal discomfort.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Aurolab

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Flures 20% w/v Injection 3 ml

Flures 20% w/v Injection 3 ml is a diagnostic dye used by eye specialists to examine blood flow in the back of the eye. It helps doctors detect, assess, and monitor problems affecting the retina and its blood vessels, including changes caused by diabetes.

Flures 20% w/v Injection 3 ml travels through the bloodstream to the blood vessels in the eye. A special camera takes pictures as the dye passes through these vessels, helping your doctor identify areas where blood flow is blocked or where blood vessels are leaking.

Flures 20% w/v Injection 3 ml is given as an injection into a vein by a trained healthcare professional during an eye examination. Before the injection, eye drops are usually used to widen your pupils so the retina can be examined clearly. Pupil dilation often takes about 20–30 minutes, and the overall appointment may take around 60–90 minutes, although this can vary depending on the tests required.

Common effects include nausea and temporary yellow colouring of the skin or urine as the dye leaves the body. Serious allergic reactions are uncommon, but tell the medical team immediately if you develop difficulty breathing, hives, severe dizziness, or swelling of the face or throat.

Before the test, tell your doctor if you have previously had a severe reaction to fluorescein, or if you have asthma, severe allergies, kidney problems, or pheochromocytoma (a rare tumour of the adrenal gland). Also tell your doctor about all medicines you take and if you are pregnant, planning to become pregnant, breastfeeding, or are an older adult, as additional precautions may be needed.

Uses of Flures 20% w/v Injection 3 ml

Flures 20% w/v Injection 3 ml is used during fluorescein angiography to help doctors examine blood flow and blood vessels in the retina.

  • Retinal angiography: Flures 20% w/v Injection 3 ml helps show blood flow in the retina so your doctor can identify blocked, damaged, or leaking blood vessels.
  • Diabetic retinopathy: It helps doctors assess and monitor changes in the small blood vessels of the retina caused by diabetes.
  • Macular degeneration: It can help identify abnormal or leaking blood vessels associated with certain forms of macular degeneration and support treatment planning.

Key Benefits

Fluorescein angiography provides information about retinal blood flow that can help your doctor assess eye conditions and plan appropriate care.

  • Provides detailed blood vessel images: Flures 20% w/v Injection 3 ml makes retinal blood vessels easier to see during imaging, including areas of leakage or abnormal blood flow.
  • Helps identify changes that may need treatment: The images can help your doctor find and assess changes in the retina that may not be fully visible during a routine eye examination.
  • Supports treatment planning and follow-up: The test can help your doctor decide whether treatment is needed and monitor changes in the eye over time.

Directions for Use

  • Your doctor will decide the dosage and timing of Flures 20% w/v Injection 3 ml before the imaging procedure.
  • Flures 20% w/v Injection 3 ml will be administered by a doctor or nurse in a healthcare facility.
  • Do not self-administer.

How Flures 20% w/v Injection 3 ml Works

Flures 20% w/v Injection 3 ml contains fluorescein sodium, a dye that gives off light when exposed to a specific type of blue light. After it is injected into a vein, the dye travels through the bloodstream and reaches the blood vessels in the retina and choroid at the back of the eye. A special camera takes a series of images as the dye passes through these vessels, allowing your doctor to see areas where blood flow is abnormal or where dye leaks from damaged or abnormal blood vessels.
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Alcohol

Caution

Consumption of alcohol should be avoided.

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Pregnancy

Caution

Before taking Flures 20% w/v Injection 3 ml, tell your doctor if you are pregnant or suspect you may be pregnant. Your doctor will determine whether or not to give you this medicine.

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Breast Feeding

Caution

Avoid breastfeeding for two days after receiving fluorescein sodium since it is excreted in breast milk.

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Driving

Caution

The angiography technique dilates the pupil. Patients must refrain from driving or using machinery until their eyesight is normal.

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Liver

Caution

Limited information is available about using Flures 20% w/v Injection 3 ml in patients with liver disease. Inform your doctor before receiving the Flures 20% w/v Injection 3 ml if you have a history of liver diseases/conditions. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Inform your doctor before receiving the Flures 20% w/v Injection 3 ml if you have a history of kidney diseases/conditions. Your doctor may adjust your dose depending on your current kidney conditions. If you are on kidney dialysis, your dose may be reduced to half the recommended dose.

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Children

Unsafe

It should not be used in people under the age of 18.

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Heart

Caution

Inform your doctor before receiving the Flures 20% w/v Injection 3 ml if you have heart disease. Your doctor will prescribe only if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Limited information available about the use of Flures 20% w/v Injection 3 ml in geriatric patients. Please consult your physician.

What if I have taken an overdose of Flures 20% w/v Injection 3 ml

Flures 20% w/v Injection 3 ml is prepared and given by trained healthcare professionals, so receiving too much is unlikely. You will be monitored during the procedure. Tell the medical team immediately if you feel seriously unwell or develop symptoms such as difficulty breathing, chest discomfort, severe dizziness, or fainting.

Diet & Lifestyle Advise

  • Follow your clinic's food instructions: Your healthcare team will tell you whether you can eat normally or should avoid food for a period before the test.
  • Stay hydrated: Unless your doctor has advised you to limit fluids, drinking enough water after the test can support normal removal of the dye through the urine.
  • Bring sunglasses: Dilating eye drops can make your eyes sensitive to bright light for several hours. Sunglasses may make you more comfortable after the examination.
  • Avoid driving until your vision is clear: Pupil dilation can temporarily cause blurred vision and sensitivity to light. Wait until your vision has returned to normal before driving or doing tasks that require clear vision.
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How Soon It Starts Working

The time required for Flures 20% w/v Injection 3 ml to start to work: The onset of time for Flures 20% w/v Injection 3 ml varies based on the individual. The time for which the effects of Flures 20% w/v Injection 3 ml last: The duration of Flures 20% w/v Injection 3 ml effect is unknown.

What if you forget to take Flures 20% w/v Injection 3 ml

Flures 20% w/v Injection 3 ml is used during a planned diagnostic procedure rather than taken on a regular schedule, so there is usually no daily dose to miss. If you cannot attend your scheduled appointment, contact the clinic to arrange another appointment.

Storage

• Flures 20% w/v Injection 3 ml is usually stored and handled by the healthcare facility where the procedure is performed.
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Keep Refrigerated. Do not freeze.

Drug Warnings

  • Mention previous reactions: Tell your healthcare team if you have ever had a severe allergic reaction to fluorescein before.
  • Share your medical history: Tell your doctor if you have asthma, severe allergies, kidney problems, or pheochromocytoma (a rare tumour of the adrenal gland), as these may require additional consideration before the procedure.
  • Tell the team about your medicines: In particular, mention beta-blockers and any other prescription, over-the-counter, or herbal medicines you use.
  • Report discomfort during injection: Tell the medical team if you notice burning, pain, or swelling around the injection site. If the dye leaks outside the vein, staff can stop the injection, examine the area, and provide appropriate local care.
  • Expect temporary colour changes: Your skin or urine may temporarily appear yellow or orange as fluorescein leaves your body.
  • Plan for pupil dilation: Your pupils may take around 20–30 minutes to dilate, and the full appointment may take around 60–90 minutes depending on the examination and imaging required.

Drug-Drug Interactions

verifiedApollotooltip
  • Beta-blockers: Medicines such as propranolol, atenolol, or metoprolol are used for conditions such as high blood pressure and heart problems. Beta-blockers may make a serious allergic reaction more difficult to treat if one occurs. Tell your healthcare team if you take one of these medicines.
FluoresceinBenazepril
Severe

Drug-Drug Interactions

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FluoresceinBenazepril
Severe
How does the drug interact with Flures 20% w/v Injection 3 ml:
Taking Flures 20% w/v Injection 3 ml with benazepril may increase the risk of allergic reactions.

How to manage the interaction:
Although there is an interaction between Flures 20% w/v Injection 3 ml and Benazepril, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • Food: No specific clinically important food interaction with fluorescein sodium is expected. Follow the preparation instructions given by your clinic about eating or drinking before the procedure.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[OPHTHALMOLOGIC AGENTS]

FAQs

Flures 20% w/v Injection 3 ml is used in Eye Examination as a diagnostic agent.
Flures 20% w/v Injection 3 ml contains the active ingredient fluorescein sodium, which belongs to a class of medications known as diagnostic tools for particular eye tests such as Fluorescein angiography. Fluorescein angiography is a test that allows the blood vessels in the back of the eye to be photographed as a fluorescent dye is injected into the bloodstream. This will assist your doctor in the diagnosis of diseases that affect these blood vessels, especially in elderly people and diabetics.
If an X-ray procedure is performed within 36 hours of injection, the great visibility of particular organs, such as the kidneys, may cause misinterpretation of the results.
Your pupils are usually dilated for the test, which can temporarily blur your vision and make your eyes sensitive to light. Do not drive until your vision has returned to normal. Arrange for someone to take you home if advised by your clinic.
Your pupils usually need time to dilate before the imaging begins, often around 20–30 minutes. The full appointment may take around 60–90 minutes, although the exact time varies depending on the clinic and the imaging needed.
Fluorescein is removed mainly through the urine. Yellow or orange urine and mild yellow colouring of the skin can occur temporarily after the test and usually fade as the dye leaves your body.
You may feel a brief pinch when the needle is placed into your vein. Tell the healthcare team immediately if you develop burning, significant pain, or swelling around the injection site.
If fluorescein leaks into the tissue around the vein, you may notice pain, burning, or swelling. The healthcare team will stop the injection and examine the area. Depending on the amount of leakage and your symptoms, they may elevate the affected limb, apply a cold compress, and monitor the area until it improves.
Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding before the procedure. Your doctor will consider whether fluorescein angiography is needed and discuss the possible benefits and risks with you.
Fluorescein is a yellow-coloured dye. As it moves through your body and is removed in the urine, it can temporarily change the colour of your skin and urine. This effect usually goes away as the dye leaves your body.
Tell your eye specialist and healthcare team before the test. A history of asthma or serious allergies may increase the risk of a reaction, so your healthcare team can decide what precautions are appropriate.
Preparation instructions can vary. Follow the instructions provided by your clinic about eating and drinking before the procedure rather than fasting on your own.
Other eye-imaging tests are available, including optical coherence tomography angiography (OCT-A), which can image retinal blood vessels without injecting fluorescein, and indocyanine green angiography, which uses a different dye to examine certain blood vessels in the eye. These tests provide different types of information, so your eye specialist will recommend the option that best suits what needs to be examined.
Older adults can undergo fluorescein angiography when their doctor considers it appropriate. Tell your healthcare team about your medical conditions, kidney problems, allergies, and medicines so they can plan the procedure safely.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

No: 1 , Sivagangai Main Road, Veerapanjan, Madurai - 625 020, Tamil Nadu, India.
Other Info - FLU0616
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