apollo
0

Welcome User

Login/Sign Up

Home
Buy Medicines
Lab Tests
Doctor Consult
Circle Membership
insurance
Blogs
Contact Us
Privacy Policy
Return & Refunds
Need Help
Terms and Conditions
  1. Home
  2. Medicine

  3. Fludabine 50 mg Injection 1's

Prescription drug
Trailing icon
Fludabine 50 mg Injection 1's, Pack of 1 INJECTION
Offers on medicine orders
All offers
axis icici
Written By Lakshmithulasi Yarragunta ,
Reviewed By Santoshini Reddy G , M Pharmacy

Fludabine 50 mg Injection is used to treat Chronic lymphocytic leukaemia. Fludabine 50 mg Injection contains Fludarabine, which works by inhibiting DNA synthesis (responsible for DNA elongation, synthesis, and repair) in cancer cells by interfering with the ribonucleotide reductase and DNA polymerase enzymes. Thus, it slows or stops the growth of cancer cells in the body. Common side effects of this medicine may include fever, chills, hair loss, depression, fatigue, vomiting, nausea, headache, cough, constipation, oedema, weakness, and pain at the injection site.

Read more

Synonym :

FLUDARABINE PHOSPHATE

Composition :

FLUDARABINE-50MG

Manufacturer/Marketer :

Dr Reddy's Laboratories Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Fludabine 50 mg Injection

Fludabine 50 mg Injection belongs to a group of anticancer medicines called purine analogue used in the treatment of chronic lymphocytic leukaemia. Leukaemia, also known as blood cancer, is a cancer of blood cells or blood-forming tissues. It causes excessive production of immature white blood cells by the bone marrow and reduces the body’s ability to fight infections. 

Fludabine 50 mg Injection contains Fludarabine, which works by inhibiting DNA synthesis (responsible for DNA elongation, synthesis, and repair) in cancer cells by interfering with the ribonucleotide reductase and DNA polymerase enzymes. Thus, Fludabine 50 mg Injection slows or stops the growth of cancer cells in the body.

Fludabine 50 mg Injection may cause certain side effects such as fever, chills, hair loss, depression, fatigue, vomiting, nausea, headache, cough, constipation, oedema, weakness, and pain at the site of injection. Most of these side effects of Fludabine 50 mg Injection do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please seek medical help. A trained healthcare professional will administer Fludabine 50 mg Injection. Hence, do not self-administer.

If you are allergic to Fludabine 50 mg Injection, inform your doctor and avoid taking it. Inform your doctor about your complete medical and medication history before starting treatment with Fludabine 50 mg Injection. Fludabine 50 mg Injection is contraindicated for pregnant women and breastfeeding women due to serious embryo-fetal toxicity. Hence, consult your doctor if you are pregnant, planning to become pregnant or breastfeeding. Let the doctor know if you have/had kidney or liver disease, hemolytic anaemia, severe bone marrow suppression, thrombocytopenia, or neutropenia before starting the treatment, as it may worsen your condition. Inform your doctor if you have received any vaccination before starting the treatment.

Uses of Fludabine 50 mg Injection

Fludabine 50 mg Injection is used in the treatment of Chronic lymphocytic leukemia. The detailed use of Fludabine 50 mg Injection is as follows:<br/>• Chronic Lymphocytic Leukemia (CLL): Fludabine 50 mg Injection is used in the treatment of chronic lymphocytic leukemia (CLL).<br/>

Have a query?

Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.• Fludabine 50 mg Injection will be administered by the doctor or healthcare professional.• Do not self-administer.

Medicinal Benefits

Fludabine 50 mg Injection contains Fludarabine, which belongs to the class of purine analogues. It works by inhibiting DNA synthesis (responsible for DNA elongation, synthesis, and repair) in cancer cells by interfering with the ribonucleotide reductase and DNA polymerase enzymes. Thus, Fludabine 50 mg Injection stops the multiplication of abnormal cells and causes the death of cancer cells.

How Fludabine 50 mg Injection Works

Fludabine 50 mg Injection contains Fludarabine, which works by inhibiting DNA synthesis (responsible for DNA elongation, synthesis, and repair) in cancer cells by interfering with the ribonucleotide reductase and DNA polymerase enzymes. Thus, Fludabine 50 mg Injection slows or stops the growth of cancer cells in the body.

Storage

• Store in a cool and dry place away from sunlight.
• Keep Fludabine 50 mg Injection out of the sight and reach of children.
• Cold chain - To be stored in cold places at 2ºC to 8ºC.
Side effects of Fludabine 50 mg Injection
  • Eat well-cooked food to minimize infection risk.
  • Practice good hand hygiene to prevent infections.
  • Avoid crowds and people with illnesses to reduce exposure.
  • Wear a mask when necessary to lower infection risk.
  • Rest adequately to support your body's healing process.
  • Stay hydrated by drinking plenty of water.
  • Regularly monitor blood cell counts for changes.
  • Seek immediate medical help if symptoms like fever, chills, or fatigue occur.
  • Consult your doctor right away if concerning symptoms arise.
  • Follow your doctor's guidance on managing myelosuppression and infection prevention.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
  • Rest well; get enough sleep.
  • Wear comfortable layers of clothes and get to a warm place.
  • Drink warm fluids like coffee, tea or hot chocolate.
  • Warm up using a blanket or heating pad.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • Wash your hands regularly with soap and water or use a hand sanitizer to prevent the spread of infections.
  • Wear masks, gloves and other protective clothing.
  • Cover sneezes and coughs with a medical mask or tissue or your elbow.
  • Take vaccinations to enhance your immunity to specific diseases.
  • Clean your utensils, linen and surfaces regularly.
Here are the steps to manage the medication-triggered Cough:
  • Tell your doctor about the cough symptoms you're experiencing, which may be triggered by your medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your cough symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids, such as water, tea, or soup, to help thin out mucus and soothe your throat.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your cough persists or worsens, consult your doctor for further guidance.

What if I have taken an overdose of Fludabine 50 mg Injection

Since Fludabine 50 mg Injection is given in a controlled medical setting by a healthcare professional, an overdose is not likely to occur. If you think there has been an overdose or experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly. Overdose of Fludabine 50 mg Injection may cause unusual bruising or bleeding, fever, chills, cough, sore throat, or other signs of infection, delayed blindness, and coma.

Drug Warnings

If you are allergic to Fludabine 50 mg Injection, inform your doctor and avoid taking it. Inform your doctor about your complete medical and medication history before starting treatment with Fludabine 50 mg Injection. Fludabine 50 mg Injection is contraindicated for pregnant women and breastfeeding women due to serious embryo-fetal toxicity. Hence, consult your doctor if you are pregnant, planning to become pregnant or breastfeeding. Let the doctor know if you have/had kidney or liver disease, haemolytic anaemia, severe bone marrow suppression, thrombocytopenia (low number of platelets), or neutropenia (low white blood cells) before starting the treatment, as it may worsen your condition. If you are about to receive any vaccinations, inform your doctor that you are taking Fludabine 50 mg Injection as it may cause infection.

Drug-Drug Interactions

verifiedApollotooltip
FludarabineThalidomide
Severe
FludarabineEtanercept
Severe

Drug-Drug Interactions

Login/Sign Up

FludarabineThalidomide
Severe
How does the drug interact with Fludabine 50 mg Injection:
Taking thalidomide together with Fludabine 50 mg Injection may increase the risk of blood clots and other complications.

How to manage the interaction:
Although taking thalidomide and Fludabine 50 mg Injection together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.
FludarabineEtanercept
Severe
How does the drug interact with Fludabine 50 mg Injection:
When Etanercept is used with Fludabine 50 mg Injection, the likelihood or severity of infection may increase.

How to manage the interaction:
Co-administration of Etanercept with Fludabine 50 mg Injection can result in an interaction, but it can be taken if a doctor has advised it. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
FludarabineCladribine
Severe
How does the drug interact with Fludabine 50 mg Injection:
Taking Cladribine with Fludabine 50 mg Injection can increase the risk of developing serious infections.

How to manage the interaction:
Co-administration of Fludabine 50 mg Injection with Cladribine can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
FludarabineBaricitinib
Severe
How does the drug interact with Fludabine 50 mg Injection:
Coadministration of baricitinib and Fludabine 50 mg Injection can raise the risk of developing serious infections.

How to manage the interaction:
Although there is an interaction, baricitinib can be taken with Fludabine 50 mg Injection if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not discontinue any medication without consulting a doctor.
FludarabineInfliximab
Severe
How does the drug interact with Fludabine 50 mg Injection:
Combining Infliximab with Fludabine 50 mg Injection can increase the risk or severity of developing serious infections.

How to manage the interaction:
There may be a possibility of interaction between Fludabine 50 mg Injection and Infliximab, but it can be taken if prescribed by a doctor. If you have any of these symptoms like fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, losing weight, and pain or burning when you pee, it's important to contact a doctor right away. Do not stop using any medications without a doctor's advice.
FludarabineClozapine
Severe
How does the drug interact with Fludabine 50 mg Injection:
Co-administration of Fludabine 50 mg Injection with Clozapine can increase the risk of neutropenia (low levels of neutrophils in blood).

How to manage the interaction:
There may be a possibility of interaction between Fludabine 50 mg Injection and Clozapine, but it can be taken if prescribed by a doctor. If you experience any symptoms such as infection, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, or pain or burning during urination, it is important to contact a doctor right away. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

Login/Sign Up

Diet & Lifestyle Advise

  • Maintain a balanced diet including fruits and vegetables rich in nutrients and low-fat proteins like lean meats, fish and poultry.
  • Drink plenty of water daily while taking the medication, as some cancer therapies may cause dehydration.
  • Exercise regularly and maintain a healthy body weight.
  • Regularly wash your hands and avoid contact with people having infections.
  • Quit smoking.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

Fludabine 50 mg Injection Substitute

Substitutes safety advice
bannner image

Alcohol

Caution

It is not known if alcohol interacts with Fludabine 50 mg Injection. Please consult the doctor.

bannner image

Pregnancy

Unsafe

Fludabine 50 mg Injection is not recommended for use in pregnancy as it may harm the foetus. Hence, if you are pregnant or planning pregnancy, inform your doctor before receiving Fludabine 50 mg Injection. You should not become pregnant while on treatment with Fludabine 50 mg Injection.

bannner image

Breast Feeding

Unsafe

Fludabine 50 mg Injection is not recommended for use in breastfeeding as it may pass into breast milk and harm your infant. If you are breastfeeding, inform your doctor before receiving Fludabine 50 mg Injection. Your doctor may suggest you stop feeding while on treatment with this medicine.

bannner image

Driving

Caution

Fludabine 50 mg Injection will be administered in a hospital setting. Hence, driving is not recommended.

bannner image

Liver

Caution

If you have a pre-existing or a history of liver disease, inform your doctor before receiving Fludabine 50 mg Injection.

bannner image

Kidney

Caution

If you have a pre-existing or a history of kidney disease, inform your doctor before receiving Fludabine 50 mg Injection. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

bannner image

Children

Consult your doctor

It is unknown whether Fludabine 50 mg Injection can be given to children or not. Therefore, consult your paediatrician if needed.

FAQs

Fludabine 50 mg Injection is used to treat Chronic lymphocytic leukemia.

Fludabine 50 mg Injection contains Fludarabine, which works by inhibiting the production of genetic material (DNA) in cancer cells by interfering with the ribonucleotide reductase and DNA polymerase enzymes.

If you are about to receive any vaccinations, it is advised to inform your doctor that you are on treatment with Fludabine 50 mg Injection as it may cause infections.

Fludabine 50 mg Injection may interfere with the normal menstrual cycle in women and may stop sperm production in men. Therefore, please consult a doctor if you plan to have a baby.

Country of origin

India

Manufacturer/Marketer address

Dr. Reddy'S Laboratories Ltd., 8-2-337, Road No. 3, Banjara Hills, Hyderabad, Telangana 500034, India
Other Info - FLU0203

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
icon image

Keep Refrigerated. Do not freeze.Prepaid payment required.

Author Details

Santoshini Reddy GDoctor badge

Reviewed By

Santoshini Reddy G

M Pharmacy

Last Updated

Jul 18, 2025 | 9:22 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://go.drugbank.com/drugs/DB01073
  2. https://medlineplus.gov/druginfo/meds/a692003.html
  3. https://www.cancerresearchuk.org/about-cancer/treatment/drugs/fludarabine
  4. https://reference.medscape.com/drug/fludara-oforta-fludarabine-342217
  5. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=cf5255cc-91fd-4132-973b-764dba142eae

Buy best Neoplastic Disorders products by

whatsapp Floating Button