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compositionComposition:FLUCONAZOLE-200MG
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Prescription Medicine
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Fluconazole 200 mg/100 ml I.V. is an antifungal medication used i the treatment of fungal and yeast infections. This medicine works by stopping the enzyme that is responsible for fungal growth and leading to the death of the microbes. Common side effects include headache, diarrhoea, nausea, stomach upset, dizziness, and stomach pain.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
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More about the Product

Composition :

FLUCONAZOLE-200MG

Manufacturer/Marketer :

3M India Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Fluconazole 200 mg/100 ml I.V.

Fluconazole 200 mg/100 ml I.V. is an injectable medication used to treat serious fungal infections throughout the body. It is prescribed for severe conditions such as yeast infections in the bloodstream, throat, or the linings of the brain and spinal cord. Doctors use this medicine to target and clear these deep-seated infections quickly and effectively.

Since this medication is delivered directly into a vein, it is typically given once a day at a highly consistent time to keep steady levels in your body. It is injected directly into the bloodstream, meaning its absorption is not affected by food. Eating a nutrient-rich, balanced diet and resting well can further support your immune system during your recovery.

While using Fluconazole 200 mg/100 ml I.V., you may experience mild side effects like nausea, headaches, or stomach upset. However, you must contact your doctor immediately if you experience signs of liver damage, such as yellowing of your skin or eyes, dark urine, or severe abdominal pain.

Before starting treatment, tell your doctor if you have kidney disease, liver disease, or a history of heart rhythm problems. Do not take this if you are allergic to similar antifungal medicines or if you are taking specific medications that can affect your heart rhythm.

This medicine can interact with several drugs, including certain blood thinners and diabetes medications, which can lead to unsafe side effects. Let your doctor know if you drink alcohol regularly, and consult your healthcare provider if you are pregnant, breastfeeding, or caring for an elderly patient.

Uses of Fluconazole 200 mg/100 ml I.V.

Fluconazole 200 mg/100 ml I.V. is used to treat and prevent serious fungal infections by eliminating the fungi responsible for the infection and preventing them from spreading further in the body:

  • Systemic candidiasis: Fluconazole 200 mg/100 ml I.V. helps clear severe yeast infections that have spread into the bloodstream or major organs.
  • Cryptococcal meningitis: This medication helps treat dangerous fungal infections affecting the membranes surrounding the brain and spinal cord.
  • Esophageal candidiasis: It helps resolve painful yeast infections in the throat and food pipe when swallowing pills is difficult or ineffective.
  • Fungal infection prevention: It helps protect vulnerable patients, such as those undergoing bone marrow transplants, from developing life-threatening fungal overgrowths.

Key Benefits

Fluconazole 200 mg/100 ml I.V. helps control serious fungal infections quickly while providing reliable treatment for patients who cannot take oral medicines.

  • Rapid treatment of severe infections: Intravenous administration delivers the medicine directly into the bloodstream, allowing it to begin fighting the fungal infection without relying on absorption through the digestive system.
  • Relieves infection-related symptoms: Helps reduce symptoms such as fever, pain, inflammation, and discomfort as the fungal infection comes under control.
  • Suitable when oral treatment is not possible: Provides an effective treatment option for patients who are unable to swallow tablets or capsules because of illness or medical procedures.
  • Reduces the risk of complications: By treating or preventing invasive fungal infections promptly, it helps lower the risk of infection spreading to vital organs and supports a smoother recovery.
Side effects of Fluconazole 200 mg/100 ml I.V.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Fluconazole 200 mg/100 ml I.V. will be administered by the doctor or healthcare professional.
  • Do not self-administer.

How Fluconazole 200 mg/100 ml I.V. Works

Fluconazole 200 mg/100 ml I.V. contains fluconazole, an antifungal medicine that helps treat fungal infections by stopping the growth and spread of fungi. Fluconazole 200 mg/100 ml I.V. works by blocking an enzyme that fungi need to produce ergosterol, an essential component of their protective cell membrane. Without enough ergosterol, the fungal cell membrane becomes weak and damaged, preventing the fungi from growing and multiplying. This allows the body's immune system to eliminate the remaining fungal cells and clear the infection. Together, these actions help treat fungal infections, relieve associated symptoms, and prevent the infection from spreading further.
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Alcohol

Caution

It is advisable to avoid or limit the intake of alcohol while on treatment with Fluconazole 200 mg/100 ml I.V..

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Pregnancy

Consult your doctor

Please consult your doctor if you are pregnant or are planning to conceive before starting Fluconazole 200 mg/100 ml I.V..

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Breast Feeding

Caution

Fluconazole 200 mg/100 ml I.V. should be used with caution and only under a doctor's advice if you are a lactating mother. Please seek medical advice for more information.

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Driving

Caution

Fluconazole 200 mg/100 ml I.V. may sometimes cause dizziness or other side effects that may affect your mental ability to drive. Hence do not drive or operate machinery if you are not mentally alert.

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Liver

Consult your doctor

Let your doctor know if you have any history of liver diseases when you are prescribed Fluconazole 200 mg/100 ml I.V..

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Kidney

Consult your doctor

Let your doctor know if you have any history of kidney diseases when you are prescribed Fluconazole 200 mg/100 ml I.V..

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Children

Caution

Fluconazole 200 mg/100 ml I.V. should be given to children only when prescribed by a doctor. The doctor decides the right dose for a child based on his/her age and weight.

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Heart

Caution

Fluconazole 200 mg/100 ml I.V. should be used with caution in patients with heart problems. Therefore, please consult your doctor before using Fluconazole 200 mg/100 ml I.V..

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Geriatrics

Caution

Fluconazole 200 mg/100 ml I.V. should be used with caution in elderly patients due to an increased risk of side effects. It is important to consult a healthcare professional before use.

What if I have taken an overdose of Fluconazole 200 mg/100 ml I.V.

If you receive too much of this medicine, you may experience severe confusion, hallucinations, or unusual physical movements. If you suspect an overdose, seek emergency medical attention or contact a poison control centre immediately.

Diet & Lifestyle Advise

  • Limit sugar intake: Yeast and fungi thrive on sugars, so reducing sugary snacks and refined carbohydrates can help support your treatment.
  • Stay well-hydrated: Drinking plenty of water helps your kidneys process and clear the medication safely from your body.
  • Support your gut health: Ask your doctor if taking a high-quality probiotic is appropriate for you, as clearing a fungal infection can sometimes affect your natural balance of microflora.
  • Maintain strict hygiene: Keep injection sites clean and dry, and practice good personal hygiene to prevent secondary bacterial infections.
health query

Have a query?

How Soon It Starts Working

The time required for Fluconazole 200 mg/100 ml I.V. to start to work: The time required for Fluconazole 200 mg/100 ml I.V. to show its action is unknown.

The time for which the effects of Fluconazole 200 mg/100 ml I.V. last: The duration of action for Fluconazole 200 mg/100 ml I.V. is unknown.

What if you forget to take Fluconazole 200 mg/100 ml I.V.

Because this medicine is usually given by a healthcare professional, a missed dose is highly unlikely. However, if you are managing your treatment at home and miss a scheduled dose, contact your doctor or nurse immediately for advice. Do not inject a double dose to make up for a missed one.

Storage

• Store Fluconazole 200 mg/100 ml I.V. at room temperature, ideally between 20°C and 25°C (68°F to 77°F).

Drug Warnings

  • Inspect the liquid: Always check the solution before use; it should be clear and colourless. Do not inject it if you see particles, cloudiness, or discolouration.
  • Do not mix medications: Never mix other drugs in the same IV bag or line with Fluconazole 200 mg/100 ml I.V. unless explicitly instructed by a pharmacist.
  • Watch the injection site: Check the IV site daily for redness, swelling, pain, or leaking, and report any irritation to your nurse or doctor immediately.
  • Dispose of needles safely: Always place used needles and infusion lines directly into a puncture-resistant sharps container immediately after use.
  • Monitor liver and kidney function: If you are on a long-term course of this medication, make sure to attend all scheduled blood test appointments so your doctor can monitor your organs.

Drug-Drug Interactions

verifiedApollotooltip

The following medicines may interact with Fluconazole 200 mg/100 ml I.V.:

  • Heart rhythm medications: Medicines such as erythromycin, quinidine, or pimozide may increase the risk of serious heart rhythm abnormalities when used with Fluconazole 200 mg/100 ml I.V..
  • Blood thinners: Fluconazole 200 mg/100 ml I.V. can increase the effect of medicines such as warfarin, raising the risk of bruising and bleeding.
  • Oral diabetes medicines: Medicines such as glipizide or glyburide may increase the risk of low blood sugar when taken with Fluconazole 200 mg/100 ml I.V..
FluconazoleLomitapide
Critical
FluconazoleAstemizole
Critical

Drug-Drug Interactions

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FluconazoleLomitapide
Critical
How does the drug interact with Fluconazole 200 mg/100 ml I.V. 200 mg/100 ml I.V.:
When Lomitapide is taken with Fluconazole 200 mg/100 ml I.V., may increase the blood levels of lomitapide.

How to manage the interaction:
Taking Fluconazole 200 mg/100 ml I.V. with Lomitapide together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark-colored urine, light-colored stools, and yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
FluconazoleAstemizole
Critical
How does the drug interact with Fluconazole 200 mg/100 ml I.V. 200 mg/100 ml I.V.:
When Astemizole is taken with Fluconazole 200 mg/100 ml I.V., the body's ability to break down Astemizole may be reduced.

How to manage the interaction:
Taking Fluconazole 200 mg/100 ml I.V. with Astemizole can lead to an interaction, please consult a doctor before taking it. Do not discontinue the medications without of consulting a doctor.
FluconazoleErythromycin
Critical
How does the drug interact with Fluconazole 200 mg/100 ml I.V. 200 mg/100 ml I.V.:
Taking Fluconazole 200 mg/100 ml I.V. with Erythromycin can increase the risk of heart rhythm problems.

How to manage the interaction:
Taking Fluconazole 200 mg/100 ml I.V. with Erythromycin together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
FluconazoleEliglustat
Critical
How does the drug interact with Fluconazole 200 mg/100 ml I.V. 200 mg/100 ml I.V.:
When Eliglustat and Fluconazole 200 mg/100 ml I.V. are taken together, Fluconazole 200 mg/100 ml I.V. can significantly increase the blood levels of eliglustat.

How to manage the interaction:
Taking Fluconazole 200 mg/100 ml I.V. with Eliglustat together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, shortness of breath, slow heart rate, weak pulse, or heart palpitations. Do not discontinue any medications without consulting a doctor.
FluconazoleBosutinib
Severe
How does the drug interact with Fluconazole 200 mg/100 ml I.V. 200 mg/100 ml I.V.:
Taking bosutinib with Fluconazole 200 mg/100 ml I.V. can increase the blood levels of bosutinib. This can increase side effects such as nausea, vomiting, abdominal pain, and diarrhea.

How to manage the interaction:
Although there is a possible interaction, Fluconazole 200 mg/100 ml I.V. can be taken with Bosutinib if prescribed by the doctor. However, consult your doctor if you experience fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting a doctor.
FluconazoleDeflazacort
Severe
How does the drug interact with Fluconazole 200 mg/100 ml I.V. 200 mg/100 ml I.V.:
Co-administration of Fluconazole 200 mg/100 ml I.V. with Deflazacort can increase the levels of Deflazacort in the body.

How to manage the interaction:
Taking Fluconazole 200 mg/100 ml I.V. with Deflazacort together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience symptoms like muscle weakness, excessive growth of facial or body hair, or sudden dizziness, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
FluconazoleBuspirone
Severe
How does the drug interact with Fluconazole 200 mg/100 ml I.V. 200 mg/100 ml I.V.:
When used with Fluconazole 200 mg/100 ml I.V. with Buspirone may result in sleepiness, lightheadedness, irregular heart rate, depression, unusual thoughts or behavior, or loss of coordination.

How to manage the interaction:
Co-administration of Buspirone with Fluconazole 200 mg/100 ml I.V. can lead to an interaction, it can be taken if recommended by a doctor. Do not discontinue any medications without consulting a doctor.
FluconazoleFentanyl
Severe
How does the drug interact with Fluconazole 200 mg/100 ml I.V. 200 mg/100 ml I.V.:
Co-administration of fentanyl and Fluconazole 200 mg/100 ml I.V. may significantly increase the blood levels and effects of fentanyl.

How to manage the interaction:
Although taking Fentanyl together with Fluconazole 200 mg/100 ml I.V. can result in an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor if you have dizziness, fainting, confusion, excessive sleepiness, and/or shortness of breath. Do not stop taking any medication without consulting a doctor.
FluconazoleAmisulpride
Severe
How does the drug interact with Fluconazole 200 mg/100 ml I.V. 200 mg/100 ml I.V.:
Taking Amisulpride with Fluconazole 200 mg/100 ml I.V. may increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although there is a possible interaction, Amisulpride can be taken with Fluconazole 200 mg/100 ml I.V. if prescribed by the doctor. Consult the doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations during treatment with these medications. Do not discontinue any medications without consulting a doctor.
FluconazoleColchicine
Severe
How does the drug interact with Fluconazole 200 mg/100 ml I.V. 200 mg/100 ml I.V.:
Coadministration of colchicine with Fluconazole 200 mg/100 ml I.V. may increase the blood levels of colchicine, increasing the risk of serious side effects.

How to manage the interaction:
Although taking Colchicine and Fluconazole 200 mg/100 ml I.V. together may result in an interaction, they can be taken together if a doctor prescribes it. However, contact a doctor immediately if you experience nausea, vomiting, abdominal pain, numbness or tingling in your hands and legs, muscle pain, or weakness. Do not discontinue any medication without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • No clinically significant food interactions are known with Fluconazole 200 mg/100 ml I.V. when used as directed.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIFUNGALS]

FAQs

Fluconazole 200 mg/100 ml I.V. belongs to the class of medicines called 'antifungals' used to treat a broad range of infections caused by fungi and yeast.
Fluconazole 200 mg/100 ml I.V. works by killing the fungus/yeast and preventing its growth by inhibiting the fungal cell membrane formation. Thus, it treats fungal infections.
Co-administration of terfenadine (anti-histamine), cisapride (antacid) with Fluconazole 200 mg/100 ml I.V. is not recommended. However, consult your doctor before taking Fluconazole 200 mg/100 ml I.V. with other medicines.
Fluconazole 200 mg/100 ml I.V. may not be suitable for some people who have a weakened immune system, diabetes, cancer, or low blood magnesium or potassium levels. However, seek a doctor's advice before using Fluconazole 200 mg/100 ml I.V. if you have a previous medical history.
Diarrhoea could be a side effect of Fluconazole 200 mg/100 ml I.V.. Drink plenty of fluids and eat non-spicy food if you experience diarrhoea. Consult your doctor if your condition does not improve or if it worsens.
This medicine is generally not recommended during pregnancy, especially in high doses, as it may harm the unborn baby. However, your doctor may still prescribe it if the benefit outweighs the risk in a life-threatening situation. Talk to your doctor about your options.
The injection is used for severe, deep-seated infections, or when a patient cannot swallow pills due to severe nausea or throat pain. It ensures that 100% of the medication enters the bloodstream immediately. Talk to your doctor to understand why this form was chosen for you.
It is highly recommended to avoid alcohol while using this medicine. Both alcohol and this drug can strain your liver, and combining them increases the risk of liver damage. Talk to your doctor or pharmacist if you have concerns.
The duration of your treatment depends entirely on how well your body responds and the type of infection being treated. Severe infections may require several weeks of therapy. Talk to your doctor about your specific treatment timeline.
If you experience pain, swelling, redness, or warmth around the injection site, notify your healthcare provider or nurse right away. These could be signs of localised irritation or infection. Talk to your doctor immediately if you notice these symptoms.
No, this medication is strictly an antifungal treatment and will not work against viruses, bacteria, or common colds. Using it inappropriately can lead to ineffective treatment. Talk to your doctor if you suspect a different type of infection.
This medication can occasionally cause dizziness or headaches in some patients. You should avoid driving or operating machinery until you know exactly how the medicine affects you. Talk to your doctor if you experience these side effects.

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Reference

  1. Drugs.com Clinical Review Team. Fluconazole Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  2. National Health Service (NHS). Fluconazole - NHS Medicines Reference Guide. London, UK: NHS; 2025. [Accessed on 02 Jun. 2026]Check here
  3. DailyMed Database. Fdadrugxsl.Cfm Clinical Monograph. Bethesda, MD: National Library of Medicine; 2025. [Accessed on 02 Jun. 2026]Check here
  4. Fluconazole Fluconazole. 2014. [Accessed on 29 Mar. 2019]Check here
  5. Diflucan 150 Capsules - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2021 [Accessed on 17 November 2021]Check here
  6. DIFLUCAN Tablets/Oral Suspension USP [Internet]. Accessdata.fda.gov. 2021 [Accessed on 17 November 2021]Check here
  7. Diflucan 150 Capsules - Patient Information Leaflet (PIL) - (emc) [Internet]. Medicines.org.uk. 2021 [Accessed on 17 November 2021]Check here

Country of origin

India

Manufacturer/Marketer address

3M India Ltd, Concorde Block, Ub City, #24, Vittal Mallya Road, Bangalore, Karnataka - 560001 India.
Other Info - FLU0012
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