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compositionComposition:METAXALONE-400MG
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Prescription Medicine
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Flexura 400 Tablet is used to relieve pain and discomfort caused by strains, sprains, and other muscle injuries. It contains Metaxalone which works by blocking the nerve impulses and pain sensations in the brain. In some cases, this medicine may cause side effects such as dizziness, sleepiness, upset stomach, and dry mouth. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

METAXALONE-400MG

Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Flexura 400 Tablet

Metaxalone oral tablets (Flexura 400 Tablet ) are prescribed to help relax muscles and relieve pain or discomfort caused by strains, sprains, or other acute muscle injuries. This medication works alongside rest, physical therapy, and other recovery measures to restore comfort and mobility.

To get the best results, you should take Flexura 400 Tablet consistently at the exact times prescribed by your doctor. You can take this medicine with or without food, but it is important to choose one way and do it the same time every day, as food can significantly change how much medicine your body absorbs. Combining this treatment with gentle daily stretching, staying well-hydrated, and resting the affected muscle will help speed up your recovery.

While taking Flexura 400 Tablet , you might experience mild side effects like drowsiness, dizziness, or a mild upset stomach. These usually fade as your body adjusts, but you must contact your doctor immediately if you notice rare but serious symptoms like severe skin rashes, yellowing of your eyes or skin, or extreme tiredness.

Before starting this medication, tell your doctor about your complete medical history, especially if you have a history of blood disorders. Do not take this if you have severe kidney damage or severe liver damage, as your body will struggle to process and clear the medicine safely.

You should avoid drinking alcohol while taking Flexura 400 Tablet because it can dangerously increase drowsiness and slow down your breathing. It is also important to consult your doctor if you are pregnant, breastfeeding, or an older adult, as these groups may require special monitoring or alternative options to avoid serious side effects.

Uses of Flexura 400 Tablet

Flexura 400 Tablet is used to help relax muscles and relieve pain or discomfort caused by strains, sprains, or other acute muscle injuries. The detailed uses of Flexura 400 Tablet are as follows:

  • Acute muscle spasms: Flexura 400 Tablet helps by relaxing tight, painful muscles that cramp up after a sudden injury or strain.
  • Musculoskeletal pain: Flexura 400 Tablet relieves severe discomfort associated with painful muscle and bone conditions, making daily physical therapy and movement easier.

Key Benefits

Flexura 400 Tablet helps relieve painful muscle spasms and muscle stiffness, improving comfort and supporting recovery from musculoskeletal conditions. By relaxing tight muscles, it helps restore normal movement and makes everyday activities easier.

  • Helps Relieve Muscle Pain and Spasms: By reducing painful muscle contractions and stiffness, Flexura 400 Tablet helps relieve localised muscle pain and improves overall comfort.
  • Improves Movement and Physical Function: As muscle tightness decreases, Flexura 400 Tablet helps restore flexibility and range of motion, making daily activities and physical therapy sessions more comfortable and effective.
  • Supports Recovery and Rest: By relieving muscle spasms and discomfort, Flexura 400 Tablet helps promote restful sleep and allows the body to focus on the natural healing and repair of injured muscle tissue.
Side effects of Flexura 400 mg Tablet
  • Get enough sleep. Maintain a regular sleep cycle.
  • Eat a healthy diet and exercise regularly.
  • Manage stress with yoga or meditation.
  • Limit alcohol and caffeine.
  • Avoid driving or operating machinery unless you are alert.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the steps to manage medication-triggered Nervousness:
  • Tell your doctor immediately if you experience symptoms of Nervousness, such as anxiety, jitteriness, or an increased heart rate, after taking medication or adjusting your medication regimen.
  • Your doctor may adjust your medication regimen to alleviate symptoms of Nervousness. This can include switching to a different medication, reducing the dosage, or temporarily stopping the medication. Your doctor may also recommend alternative techniques like relaxation, mindfulness meditation, or journaling. These techniques can help reduce anxiety and Nervousness.
  • Practice stress-reducing techniques, such as deep breathing exercises, yoga, or journaling, to help manage Nervousness.
  • Engage in regular physical activity, such as walking or jogging, to help reduce anxiety and improve mood.
  • Your doctor may advise considering cognitive-behavioural therapy (CBT) or other forms of talk therapy to address underlying anxiety or Nervousness.
  • You should maintain regular follow-up appointments with your doctor to monitor nervousness symptoms, adjust treatment plans as needed, and discuss any concerns or questions.
  • Manage stress by practising deep breathing, yoga or meditation.
  • Get enough sleep. Maintain a regular sleep cycle.
  • Exercise regularly. Try physical activities like walking, running, or dancing.
  • Limit stimulants like tea, coffee and alcohol.
  • Identify triggers and try managing them.
  • Take a break by scheduling time for yourself.
  • Try creative activities like writing, dancing or painting as it helps release tension.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.

Directions for Use

  • Take Flexura 400 Tablet with or without food as advised by your doctor.
  • Adhere to your doctor’s guidance regarding the dosage and timing of this medication for optimal effectiveness.
  • Swallow Flexura 400 Tablet as a whole with a glass of water.
  • Do not crush, chew, or break it.

How Flexura 400 Tablet Works

Metaxalone, the active drug in Flexura 400 Tablet , acts directly on the central nervous system (your brain and spinal cord) rather than targeting the muscles themselves. It works by slowing down nerve signals in the brain and spinal cord, which helps block the pain messages being sent from the injured muscle. This calming effect on the nervous system leads to overall muscle relaxation and a reduction in painful spasms. By decreasing this hyperactive nerve activity, Flexura 400 Tablet helps break the painful cycle of muscle spasm and restriction.
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Flexura 400 Tablet as it may increase drowsiness and other side effects.

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Pregnancy

Caution

Avoid taking Flexura 400 Tablet if you are pregnant unless prescribed by a doctor. Please consult your doctor if you have any concerns regarding this, your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

It is not known if Flexura 400 Tablet passes into the breastmilk, so it is not safe to breastfeed while taking Flexura 400 Tablet . Consult your doctor before taking Flexura 400 Tablet ; your doctor will decide whether Flexura 400 Tablet can be taken by breastfeeding mothers or not.

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Driving

Caution

Flexura 400 Tablet may cause drowsiness. Do not drive or operate machinery unless you are alert.

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Liver

Unsafe

Flexura 400 Tablet should not be used in liver patients as it is contraindicated in liver patients. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Unsafe

Flexura 400 Tablet should not be used in kidney patients as it is contraindicated in kidney patients. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Flexura 400 Tablet should not be given to children below 12 years as the safety and effectiveness were not established.

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Heart

Safe if prescribed

Flexura 400 Tablet can be used in heart patients if prescribed by the physician. Please consult your physician if you have any concerns.

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Geriatrics

Caution

Flexura 400 Tablet can be given in elderly patients with extreme caution, due to the increased risk of dizziness, drowsiness, or sudden falls.

What if I have taken an overdose of Flexura 400 Tablet

If you suspect an overdose, seek emergency medical attention immediately. Symptoms of an overdose may include severe drowsiness, shallow breathing, or loss of consciousness.

Diet & Lifestyle Advise

  • Use hot or cold packs on the painful muscle for 15–20 minutes at a time to ease tension and reduce swelling.
  • Drink plenty of water throughout the day to keep your muscles hydrated and prevent cramping.
  • Incorporate light, gentle stretching exercises only as recommended by your physical therapist to prevent your muscles from tightening up.
  • Avoid heavy lifting or sudden twisting movements that could re-injure the recovering muscle.
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How Soon It Starts Working

The time required for Flexura 400 Tablet to start to work: The time required for Flexura 400 Tablet to start to work is 1 hour after administration. The time for which the effects of Flexura 400 Tablet last: The effect of Flexura 400 Tablet lasts for 4 to 6 hours.

What if you forget to take Flexura 400 Tablet

If you miss a dose of Flexura 400 Tablet , take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Storage

• Store Flexura 400 Tablet tablets at room temperature, ideally between 20°C to 25°C (68°F to 77°F).

Drug Warnings

  • Avoid driving, operating heavy machinery, or performing dangerous tasks until you know how Flexura 400 Tablet affects you, as it can cause significant drowsiness.
  • Do not drink alcohol while taking this medicine, as it can worsen dizziness and cause severe drowsiness.
  • Watch for signs of liver problems, such as dark urine, persistent nausea, or yellowing of your skin or eyes, and report them to your doctor immediately.
  • Inform your doctor or surgeon that you are taking Flexura 400 Tablet before having any medical tests or surgeries, as it may interfere with certain lab results.
  • Do not share this medication with anyone else, even if they have similar symptoms of muscle pain.

Drug-Drug Interactions

verifiedApollotooltip
  • Medicines that cause drowsiness (e.g., sleeping pills, opioid pain relievers, antihistamines, or anti-anxiety medicines): Taking Flexura 400 Tablet together with other central nervous system (CNS) depressants may cause excessive drowsiness, dizziness, impaired coordination, slowed breathing, and, in severe cases, life-threatening respiratory depression. Your doctor may recommend avoiding these combinations or monitoring you closely.
     
MetaxaloneLeflunomide
Severe

Drug-Drug Interactions

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MetaxaloneLeflunomide
Severe
How does the drug interact with Flexura 400 mg Tablet:
Taking Flexura 400 mg Tablet with leflunomide can cause liver problems.

How to manage the interaction:
Although there is an interaction between leflunomide and Flexura 400 mg Tablet, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, and/or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip

High-fat meals: Taking Flexura 400 Tablet with a high-fat meal may increase the amount of medicine absorbed into your body, which can increase the risk of side effects such as drowsiness and dizziness. Follow your doctor's instructions regarding when and how to take this medicine.

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Therapeutic Class

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FAQs

Flexura 400 Tablet interacts with ibuprofen and may enhance side effects such as drowsiness. Always inform your doctor for the change of dose or an alternative drug of choice that may strictly be needed.
Flexura 400 Tablet may impair mental and/or physical abilities required for the performance of heavy tasks like operating machinery or driving a motor vehicle, especially when used with alcohol or other CNS depressants (sleeping pills or antianxiety pills).
The most common side effects related to Flexura 400 Tablet include upset stomach, dizziness, sleepiness and dryness in the mouth. However, these effects are not seen in all patients. If you are concerned about them or they do not go away, inform your doctor know.
You are advised to take Flexura 400 Tablet as advised by the doctor. The frequency of taking Flexura 400 Tablet will be determined by the doctor depending on your medical condition.
No, Flexura 400 Tablet is not addictive as it does not have habit-forming tendencies.
Yes, Flexura 400 Tablet is safe if taken in the dose and duration prescribed by the doctor.
Yes, Flexura 400 Tablet is gluten-free. However, refer to the package insert for more information.
Flexura 400 Tablet may not be indicated for a toothache as it is a muscle relaxant used to relieve muscle spasms, including pain and discomfort caused by strains, sprains, or other muscle injuries. Talk to the doctor if you have a toothache.
Yes, Flexura 400 Tablet may cause sleepiness as a side effect. Avoid driving and operating heavy machinery if you are sleepy.
Flexura 400 Tablet works by acting on the central nervous system to relax skeletal muscles, reducing muscle spasms and associated pain. It is used to relieve painful spasms of skeletal muscles.
Yes, Flexura 400 Tablet may cause tiredness as a common side effect. If you experience tiredness, stay hydrated, manage stress, sleep well, and cut out caffeine.
Flexura 400 Tablet is not known to cause constipation. If you experience constipation manage it with lifestyle changes like using good bowel habits, drinking plenty of water, taking fibre-rich food, and exercising regularly.
Flexura 400 Tablet is not known to cause highness when taken in prescribed doses. However, it may cause side effects such as dizziness and drowsiness. Consult the doctor if you have any concerns.
No, Flexura 400 Tablet does not contain acetaminophen. It contains metaxalone as an active ingredient which is a muscle relaxant.
Flexura 400 Tablet is not known to cause weight gain. If you notice any weight changes, manage it by exercising regularly, staying hydrated, cutting down on sugary drinks, taking a fibre-rich diet, and limiting processed food intake.
It is not safe to drive or operate machinery while taking Flexura 400 Tablet until you know how it affects you. This medication often causes drowsiness and dizziness, which can slow your reflexes. Talk to your doctor if you have concerns about your daily activities.
No, you should avoid alcohol while taking Flexura 400 Tablet . Alcohol can dangerously increase the sedative effects of this medication, leading to severe drowsiness, dizziness, and breathing problems. Talk to your doctor for more safety advice.
Yes, in rare cases, metaxalone can cause liver problems. You should contact your doctor immediately if you develop symptoms like yellowing of your skin or eyes, dark urine, or upper stomach pain. Talk to your doctor before starting this medicine if you have a history of liver issues.
No, Flexura 400 Tablet is not an anti-inflammatory drug like ibuprofen. It is a muscle relaxant that works on your nervous system to relieve muscle spasms and pain. Talk to your doctor about combining it with other pain relievers safely.
You should only take Flexura 400 Tablet during pregnancy or while breastfeeding if your doctor decides the benefits outweigh the risks. It is not fully known how this medicine affects unborn babies or if it passes into breast milk. Talk to your doctor to explore safer options.
If Flexura 400 Tablet causes extreme drowsiness, try taking it at a consistent time when you do not need to be alert, and make sure you are not taking it with a high-fat meal, which increases absorption. Never adjust your dose on your own. Talk to your doctor or pharmacist to find a solution.
Older adults may be more sensitive to the side effects of Flexura 400 Tablet , such as severe drowsiness, confusion, and an increased risk of falling. Doctors usually prescribe this medication with extra caution in older individuals. Talk to your doctor about the safest treatment options for muscle pain.

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Country of origin

India

Manufacturer/Marketer address

Sun Pharmaceutical Industries Ltd., SUN HOUSE, CTS No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Other Info - FLE0025

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