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Fivederm Cream is used to treat skin infections caused by microorganisms like bacteria and fungi. It kills and inhibits the growth of infection-causing microorganisms, effectively clearing the infection and relieving symptoms. It also inhibits the release of chemicals that cause symptoms like itchiness, redness, and swelling. As a result, this medicine reduces the inflammation caused by these infections. Even if your symptoms go away, you should continue to use this medicine for the duration prescribed; otherwise, they may return.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

About Fivederm Cream

Fivederm Cream is a topical combination medicine prescribed to treat certain mixed or complicated skin infections involving fungi and bacteria, along with inflammation. It is formulated to help clear up localised skin issues while relieving uncomfortable symptoms like itching, redness, and swelling. Your doctor will determine the exact duration of your treatment based on the type and severity of your skin condition.

For the best results, you must apply this medicine consistently at the same times every day as directed by your doctor. Always apply this medication to clean, dry skin, and wash your hands immediately before and after application. To help the medication work effectively, keep the affected area clean, dry, and exposed to air when possible, and avoid wearing tight, synthetic clothing that traps moisture.

Most patients tolerate this medicine well, but you may experience mild local reactions such as temporary burning, stinging, dryness, or redness at the application site. If you experience severe skin irritation, blistering, or signs of a serious allergic reaction, stop using the cream and contact your doctor immediately. If your skin condition does not improve or gets worse within the prescribed treatment period, consult your doctor.

Talk to your doctor before starting this medicine if you have thin or fragile skin, poor blood circulation, or viral skin infections like shingles, chickenpox, or herpes. Do not use this medicine if you have a known allergy to any of its active components. Because it contains clobetasol propionate, a super-high-potency steroid, it should generally not be used for more than 2 consecutive weeks unless specifically directed and monitored by a doctor. It should also be used with particular caution on the face, skin folds, and in children.

Avoid mixing this medicine with other medicated creams, ointments, or cosmetic products on the same area of skin without checking with your pharmacist first. If you are pregnant, planning to become pregnant, breastfeeding, or managing skin conditions in elderly individuals, consult your doctor to ensure this product is safe for your specific situation.

Uses of Fivederm Cream

Fivederm Cream is used in the treatment of skin infections. The detailed uses of Fivederm Cream are as follows:

  • Mixed skin infections: Treats skin conditions where both fungal and bacterial organisms are present simultaneously.
  • Inflammatory skin diseases: Relieves severe swelling, redness, and itching associated with conditions like eczema, psoriasis, and dermatitis when complicated by infection.
  • Resistant fungal infections: Clears up stubborn fungal infections, such as ringworm or athlete's foot, that have become inflamed or secondary to bacterial overgrowth.

Key Benefits

Fivederm Cream provides rapid, multi-action relief from uncomfortable skin symptoms associated with infection and inflammation. The following are the benefits of this medication:

  • Because it contains multiple active ingredients, it targets the infection from different angles, reducing the need to buy and apply several different creams throughout the day.
  • Quickly reduces inflammation and itching, helping prevent scratching of the affected area.
  • Helps protect the skin barrier from further damage and reduces the risk of spreading the infection or causing deep, painful scars.
  • Helps the skin heal more comfortably, allowing you to return to your normal daily activities without distraction.

Directions for Use

  • Fivederm Cream is typically applied 2-3 times daily.
  • Use it as directed by your doctor or as per the instructions on the label.
  • It is for external use only.
  • Clean and dry the affected skin area. Apply Fivederm Cream directly onto the affected area and gently massage it in.
  • Wash your hands before and after applying the medicine, unless your hands are the affected area.
  • If Fivederm Cream comes in contact with eyes, nose, or mouth, rinse with water immediately.

How Fivederm Cream Works

Fivederm Cream combines five distinct active agents to address infection and inflammation: Ketoconazole: It is an antifungal medicine that interferes with the production of ergosterol, an important component of the fungal cell membrane, thereby killing the fungi. Tolnaftate: It is an antifungal medicine that interferes with fungal growth and is used against certain superficial fungal skin infections. Clobetasol propionate: It is a super-high-potency topical corticosteroid. It reduces inflammation, redness, swelling, and itching by decreasing the activity of inflammatory chemicals in the skin. Neomycin: It is an antibiotic that stops bacteria from producing the essential proteins they need to grow and multiply, helping your body clear the bacterial infection. Iodochlorhydroxyquinoline: It is an antimicrobial medicine that provides broad-spectrum defence against various microbes on the skin surface. Together, these ingredients work in harmony to clear up mixed infections and soothe irritated skin.
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Alcohol

Caution

It is not known whether Fivederm Cream interacts with alcohol. However, as a precautionary measure, cut down the consumption of alcohol.

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Pregnancy

Caution

There are no competent and well-controlled pregnancy studies. Please seek medical advice from your doctor. Your doctor will only provide a prescription if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor; there has been no significant research on the use of Fivederm Cream in breastfeeding/nursing moms.

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Driving

Safe

Fivederm Cream has no or negligible influence on the ability to drive or use machines.

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Liver

Caution

Limited information is available about using Fivederm Cream in patients with liver disease. If you have any concerns about utilising Fivederm Cream in patients with liver disease, please visit your doctor. Only if the benefits outweigh the risks will your doctor prescribe.

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Kidney

Caution

Limited information is available about using Fivederm Cream in patients with kidney impairment. If you have any concerns about utilising Fivederm Cream in patients with kidney impairment, please approach your doctor. Your doctor will only provide a prescription if the benefits outweigh the risks.

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Children

Caution

Limited information was available about the use of Fivederm Cream in paediatric patients. Please seek medical advice. Your doctor will prescribe only if the benefits exceed the dangers.

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Heart

Safe if prescribed

Fivederm Cream generally doesn’t affect the heart since it’s applied externally. However, if you have severe heart problems or are on multiple medications, it’s best to consult your doctor before use.

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Geriatrics

Safe if prescribed

Fivederm Cream is generally safe for geriatric use when applied as directed. However, older adults should use it cautiously and under medical supervision to avoid side effects like skin thinning or irritation.

What if I have taken an overdose of Fivederm Cream

This medicine is for topical use only. If you or someone else accidentally swallows this cream, or if it is applied excessively over very large areas of broken skin, seek immediate medical attention or contact your local poison control centre.

Diet & Lifestyle Advise

  • Keep skin clean and dry: Gently clean the affected area and keep it dry, as excess moisture can encourage fungal and bacterial growth.
  • Wear breathable clothing: Choose loose-fitting clothes made from breathable fabrics such as cotton to reduce friction and prevent sweat from building up.
  • Use separate personal items: Use a separate towel for the affected area and avoid sharing towels, clothing, or personal care items with others.
  • Wash fabrics regularly: Wash clothes, bedsheets, and towels frequently using hot water when suitable for the fabric to help remove fungi and bacteria.
  • Avoid scratching the skin: Do not scratch or pick at the healing area, as this can introduce bacteria and slow the recovery process.
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Have a query?

How Soon It Starts Working

The time required for Fivederm Cream to start to work: The time required for Fivederm Cream to show its action is unknown. The time for which the effects of Fivederm Cream last: The duration of action for Fivederm Cream is unknown.

What if you forget to take Fivederm Cream

If you forget to apply this medicine, apply it as soon as you remember. However, if it is almost time for your next scheduled application, skip the missed application and continue with your regular schedule. Do not apply a double amount of cream to make up for a missed dose.

Storage

• Store this medicine at room temperature, ideally between 15°C and 30°C (59°F to 86°F).

Drug Warnings

  • Use on sensitive areas only if advised: Do not apply this medicine to your face, underarms, or groin unless your doctor specifically tells you to use it there.
  • Avoid contact with the eyes, nose, and mouth: Keep the cream away from these areas. If it accidentally gets into them, rinse thoroughly with plenty of cool water.
  • Do not cover the treated area: Avoid airtight dressings, plastic wraps, or tight diapers over the treated skin unless your doctor specifically advises you to do so. Covering the skin can increase steroid absorption and raise the risk of side effects.
  • Check the tube before use: Make sure the tube is sealed and the cream looks and smells normal. Do not use it if the seal is broken or if the colour or smell has changed.
  • Use only for the prescribed duration: Do not use this medicine for longer than your doctor recommends. Long-term use of strong steroid creams can cause skin thinning, stretch marks, and other lasting skin changes.
  • Use in children only if prescribed: Do not use this medicine in children under 12 years unless a paediatrician or dermatologist specifically advises it. Children can absorb more steroid through their skin and may have a higher risk of side effects affecting the whole body.
  • Tell your doctor about pregnancy or breastfeeding: Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. If you are advised to use this medicine while breastfeeding, do not apply it to the breast or nipple area where the baby could swallow it.
  • Tell your doctor about antibiotic allergies: Inform your doctor if you have previously had an allergic or skin reaction to neomycin or similar antibiotics such as gentamicin, tobramycin, amikacin, or kanamycin.

Drug-Drug Interactions

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  • Other topical treatments: Avoid using other topical steroid creams, prescription skin ointments, or strong exfoliating cosmetics on the same area of skin while using this medicine, as this can increase the risk of severe skin irritation or excessive steroid absorption.

No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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  • No clinically significant food interactions are known with Fivederm Cream when used as directed.     
     
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTI- INFECTIVES]

FAQs

Fivederm Cream is used to treat skin infections.
Fivederm Cream contains Ketoconazole, Tolnaftate, Clobetasol Propionate, Neomycin, and Iodochlorhydroxyquinoline. It inhibits the growth and multiplication of bacteria and fungi, making it an effective treatment for your skin infection.
Fivederm Cream should not be used for longer durations unless prescribed by a doctor. If your condition does not improve despite using Fivederm Cream for 2-4 weeks, consult your doctor; he/she may prescribe you an alternate medicine.
Yes, the presence of Iodochlorhydroxyquinoline in Fivederm Cream may cause yellow stains on hair, clothes, skin, and nails. As a result, it is recommended to apply Fivederm Cream with caution and avoid contact with clothing, as the stain may not be erased even with bleaching.
Yes, Fivederm Cream can be used on the face if prescribed by the doctor. However, do not apply Fivederm Cream directly on the face. Take the required quantity of Fivederm Cream onto your finger and gently massage it onto the affected face areas.
To treat your condition effectually, continue using Fivederm Cream for as long as your doctor has prescribed it. Do not hesitate to speak with your doctor if you experience difficulty using Fivederm Cream.
No, you should not use this medicine to treat acne. This medication contains a strong steroid that can actually worsen acne, cause skin thinning, and trigger other skin issues on the face. Talk to your doctor for appropriate acne treatments.
You should consult your doctor before using this medicine while breastfeeding. If your doctor advises you to use it, ensure the cream is not applied to your breast area to prevent the baby from accidentally swallowing the medicine. Talk to your doctor for personalised advice.
It is best to avoid applying makeup, cosmetics, or other skin products directly over this medicine, as they can interfere with how the medication is absorbed and irritate your skin. If you must use other products, apply them at a different time of day. Talk to your doctor or pharmacist.
If your skin condition does not improve or gets worse after a week of consistent use, contact your doctor for reassessment rather than extending treatment yourself. If the diagnosis is incorrect, the steroid component can sometimes mask or worsen an infection.
No, you should not use this medicine on infants or babies for diaper rash. The clobetasol component is a super-high-potency steroid and is not recommended for children under 12 years of age. Absorption can also increase under a diaper or other covering. Talk to your doctor for safe alternatives.
No, you should never share this medicine with anyone else, even if they have similar symptoms. It is a prescription medicine containing a very potent steroid, and similar-looking rashes can have different causes. Talk to your doctor or pharmacist.
Because this medicine is applied topically to the skin, alcohol is not expected to have a direct interaction with the topical medicine when it is used as prescribed. However, alcohol can sometimes worsen overall body inflammation and dry out your skin, which may affect healing. Talk to your doctor if you have concerns.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

SCO 6-7-8, 1st Floor, Madhya Marg, Sector 9D, Chandigarh 160009
Other Info - FIV0016
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